EPISODE · May 16, 2025 · 22 MIN
MDS Pathophysiology and the Role of Immune Dysfunction (with Dr Shahram Kordasti)
from EHA Unplugged · host European Hematology Association
In this episode, prof. Kirsten Gronbaek and dr. Shahram Kordasti discuss the role of immune dysfunction in MDS. With the improving understanding of complex pathophysiology of MDS, the major role of the immune system in this process is becoming increasingly apparent. Listen to dr. Kordasti discuss the multifactorial interactions between the malignant clones and the inflammatory environment, manifesting in elements of autoimmunity and elements of autoinflammation in MDS. As the complexity of immunophenotypes observed in MDS is being unraveled, the need to include immunophenotypic factors in the prognostic scores is growing. Tune in to hear dr. Kordasti’s and prof. Gronbaek’s thoughts on the future of prognostication, the more comprehensive approach for patient stratification designed to predict therapy responses and the future of immunotherapy in MDS.Host: Prof Kirsten GronbaekGuest: Dr Shahram KordastiLearn MoreWhat did you think of this podcast? Share your opinions with us in this short feedback survey.https://forms.monday.com/forms/d02e52896815eef59ecae09fb74dd78f?r=use1Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: [email protected] to receive the EHA Educational Updates via https://eha.news/subscribe
What this episode covers
In this episode, prof. Kirsten Gronbaek and dr. Shahram Kordasti discuss the role of immune dysfunction in MDS. With the improving understanding of complex pathophysiology of MDS, the major role of the immune system in this process is becoming increasingly apparent. Listen to dr. Kordasti discuss the multifactorial interactions between the malignant clones and the inflammatory environment, manifesting in elements of autoimmunity and elements of autoinflammation in MDS. As the complexity of immunophenotypes observed in MDS is being unraveled, the need to include immunophenotypic factors in the prognostic scores is growing. Tune in to hear dr. Kordasti’s and prof. Gronbaek’s thoughts on the future of prognostication, the more comprehensive approach for patient stratification designed to predict therapy responses and the future of immunotherapy in MDS.Host: Prof Kirsten GronbaekGuest: Dr Shahram KordastiLearn MoreWhat did you think of this podcast? Share your opinions with us in this short feedback survey.https://forms.monday.com/forms/d02e52896815eef59ecae09fb74dd78f?r=use1Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: [email protected] to receive the EHA Educational Updates via https://eha.news/subscribe
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MDS Pathophysiology and the Role of Immune Dysfunction (with Dr Shahram Kordasti)
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