Monoclonal Antibodies for Covid to Cancer to Osteoarthritis, Asthma and more. What they are & How they work

Send us Fan MailSummary:  In this episode we discuss monoclonal antibodies (the generic drug name ends in -mab), how do they work, and why can antibodies be used for so many different indications?  These indications include being used as an antiviral (against Covid till the virus mutated), a cancer treatment, against many autoimmune diseases, asthma, osteoarthritis, organ rejection and many other conditions.  Drugs made from living organisms are called biologics - these monoclonal antibodies fall into this category and are specifically targeted therapies that represent a powerful, new and evolving tool in medicine.          Topics Covered:·      Monoclonal Antibody (-mab) – big molecule 01:23·      Antigen 02:30·      Mab Production (Biologic) 03:15·      Mab Uses 04:10·      Targeted Therapy 04:40·      Desired Effect & Collateral Damage 05:30·      Prednisone 06:05·      Rheumatoid Arthritis & Inflammatory Bowel Disease 07:19·      Specificity 07:55·      Infection Risk 08:24·      MD Discussion/Shared Decision Making 09:40·      Positive, Informed and Following Up 10:30·      Insulin and Monoclonal Antibody – Injection 11:00·      Small Molecule Targeted Immunotherapy (-ib) 13:57·      Rinvoq (upadacitinib) 15:15·      JAK Inhibitors 16:23Questions and comments to  [email protected]