Neuroplasticity, Aging, and Hope: Dr. David Blake’s Latest Research Explained - #25 - June 14, 2025

Exploring Deep Brain Stimulation & Cognitive Function with Dr. David Blake | Neurostimulation PodcastJoin Michael Passmore, clinical associate professor in Psychiatry at the University of British Columbia, as he hosts Dr. David Blake, professor of neuroscience and regenerative medicine at Augusta University. In this episode, they delve into Dr. Blake's groundbreaking research on deep brain stimulation (DBS) and its effects on aging, cognitive function, and neuroplasticity. They discuss the latest findings presented at the 2025 Brain Stimulation Conference in Kobe, Japan, exploring the impact of DBS on neurotrophic markers in cerebrospinal fluid. This fascinating conversation unravels the potential of DBS in treating age-related cognitive decline, Alzheimer's disease, and broader applications such as Parkinson's disease and other neurocognitive disorders. Tune in to discover how Dr. Blake's interdisciplinary approach could revolutionize neurotherapeutics.Blake Lab: https://www.augusta.edu/mcg/dnrm/faculty/blakelab.phpCortical acetylcholine response to deep brain stimulation of the basal forebrain - Brain Stimulation Jan/Feb 2025 (Open access full text)https://www.brainstimjrnl.com/article/S1935-861X(24)00979-3/fulltextIntermittent stimulation of the basal forebrain improves working memoryin aged nonhuman primates Jan/Feb 2025 (Abstract) https://www.brainstimjrnl.com/article/S1935-861X(24)00735-6/fulltextSynchron: https://synchron.comECoG (Electrocorticography): https://en.wikipedia.org/wiki/Electrocorticography#:~:text=Electrocorticography%20(ECoG)%2C%20a%20type,activity%20from%20the%20cerebral%20cortex.00:00 Introduction to the Neurostimulation Podcast01:11 Sponsor and Guest Introduction01:43 Deep Brain Stimulation Research Overview04:04 Discussion with Dr. David Blake06:27 Dr. Blake's Research and Findings22:10 Future Directions and Applications40:14 Brain-Computer Interfaces and Neuromodulation45:10 Advice for Aspiring Neuroscientists48:54 Conclusion and Farewell