The Neurostimulation Podcast

Non-Invasive Deep Brain Stimulation: The Promise of Transcranial Focused Ultrasound with Dr. Samuel PichardoIn this episode, Dr. Michael Passmore sits down with Dr. Samuel Pichardo, biomedical engineer and researcher at the University of Calgary and the Hotchkiss Brain Institute, to explore one of the most exciting frontiers in neuromodulation: transcranial focused ultrasound stimulation (TUS/tFUS).Dr. Pichardo's lab is at the cutting edge of ultrasound neuromodulation — investigating how low-intensity pulsed ultrasound can precisely target deep brain structures non-invasively, with lasting effects on neural activity.What We Cover:What is transcranial focused ultrasound (TUS)? How it differs from TMS and tDCS, and why its ability to penetrate to deep brain structures makes it uniquely powerfulThe physics of neuromodulation: How pulsed ultrasound bursts at low frequencies (e.g., ~250 kHz) can produce neuromodulatory effects lasting 30–60 minutes after a single session — and why the underlying mechanism is still an active area of researchPulse repetition frequency (PRF): Key findings from Dr. Pichardo's lab comparing 10 Hz, 100 Hz, and 1000 Hz PRF — and why 100 Hz produced the strongest and most sustained inhibitory effectThe skull barrier: Why lower ultrasound frequencies are used to overcome skull attenuation, and the challenges this creates for precision targetingPilot clinical study — essential tremor and Parkinson's disease: Targeting the ventral intermediate nucleus (VIM) of the thalamus non-invasively, and what the results showed: significant tremor reduction in essential tremor patients, and a promising but less robust trend in Parkinson's patientsThe multi-focus targeting strategy: How Dr. Pichardo's team addressed the precision-vs.-accuracy tradeoff using phased array transducers to enlarge the treatment envelopeBabelBrain: The open-source, cross-platform (Mac, Windows, Linux) software tool developed by Dr. Pichardo's lab that integrates MRI/CT imaging data to model acoustic intensity, thermal effects, and safety parameters — a turnkey solution for TUS researchers worldwideThe future of the field: Which neuropsychiatric conditions are most likely to benefit first — including refractory depression, OCD, PTSD, and addiction — and why Dr. Pichardo believes depression may become the "poster child" indication for TUS in the next few yearsNomenclature: Why the field still hasn't settled on a consistent acronym (TUS, tFUS, LIFU, FUS) — and why that's okayKey Takeaways:Focused ultrasound can reach deep brain targets non-invasively with millimeter precision — something no other non-invasive technology can currently matchThe neuromodulatory effects are real, reproducible, and growing in clinical promise, but replication studies and sham-controlled trials are still essentialBabelBrain is freely available as an open-source tool for research labs worldwideThe field is at an inflection point, with rapid growth in FDA applications and commercial investmentLinks & Resources:Dr. Pichardo's lab at the University of Calgary / Hotchkiss Brain Institute https://www.neurofus.ca/BabelBrain (open-source TUS planning software) https://proteusmrighifu.github.io/BabelBrain/Pulse repetition frequency study (PRF paper from the Pichardo lab) https://pubmed.ncbi.nlm.nih.gov/38621645/VIM thalamic TUS pilot study (essential tremor & Parkinson's) https://pubmed.ncbi.nlm.nih.gov/8109299/Focused Ultrasound Neuromodulation Symposium, Paris (July) https://www.itrusst.com/fun26The Neurostimulation Podcast is hosted by Dr. Michael Passmore, clinical associate professor in the Department of Psychiatry at the University of British Columbia. The content shared is for educational purposes only and is not intended as medical advice. Always consult your healthcare provider regarding your specific health needs.If you enjoyed this episode, please like, subscribe, and share with anyone who might find it valuable. Drop your questions and comments below — and tune in next time for another journey into the cutting edge of neuroscience and clinical neurostimulation.

Episode Summary In this episode, Dr. Michael Passmore is joined by two guests who bring both clinical expertise and lived experience to the topic of nervous system dysregulation. Together, they explore why anxiety is far more body-based than most people realize, and how a lesser-known technology called Cranial Electrotherapy Stimulation (CES) may offer real relief for anxiety, insomnia, trauma, and chronic pain. Guests Tauna Young, Psychiatric Nurse Practitioner and founder of NeuroVana Calm — a company focused on expanding access to CES therapy. Tauna has years of clinical experience helping patients struggling with anxiety, insomnia, PTSD, and nervous system dysregulation. Cara Maxfield, entrepreneur and content creator who speaks openly about navigating trauma recovery, anxiety, panic attacks, chronic pain, and the real-world challenges of managing mental health while parenting and running a business. Topics Covered What nervous system dysregulation actually is and how it shows up in the body Why anxiety is a physical, physiological experience — not a character flaw or weakness The fight-or-flight response: when a protective mechanism becomes miscalibrated The connection between trauma, body memory, and emotional triggers What Cranial Electrotherapy Stimulation (CES) is and how it works How CES stimulates the thalamus and vagus nerve to induce a calm brain state Research comparing CES to experienced meditators' brainwave states CES FDA clearance (since 1979) and its safety profile vs. medications Clinical applications: anxiety, insomnia, PTSD, chronic pain, fibromyalgia Why CES remains largely unknown in mainstream medicine How to use CES: loading phase, daily use, and situational use Combining CES with CBT, psychotherapy, exposure therapy, and medication Cara's first-hand account of using CES during a panic attack Practical tips for regulating your nervous system Key Takeaways Anxiety is a nervous system state, not a personal weakness The body and brain are deeply interconnected — what affects one affects the other CES is portable, discreet, safe, and can be used anywhere — even the dentist CES has a 67% success rate (≥50% improvement) vs. ~45–55% for SSRIs, with far fewer side effects Tools like CES work best as part of a broader toolkit alongside therapy and lifestyle strategies Everyone has trauma to some extent — normalizing that conversation is key to healing Resources & Links 🌐 NeuroVana Calm: NeuroVanaCalm.com 📖 Free eBook from Tauna Young: A deeper dive into the science of CES — available at NeuroVanaCalm.com 📚 The Body Keeps the Score by Bessel van der Kolk (referenced in episode) https://a.co/d/0bkbVqsp Connect & Subscribe If you enjoyed this episode, please share it with someone who might benefit, leave a review, and subscribe so you never miss an episode. Drop your questions and topic ideas in the comments — your feedback shapes future episodes. The Neurostimulation Podcast is an independent educational project by Dr. Michael Passmore. All content is for educational purposes only and is not medical advice. Always consult your healthcare provider.

Episode Show NotesGuest: Dr. Ayla WolfDuration: ~48 minutesEpisode DescriptionDr. Ayla Wolf shares her personal journey from sustaining multiple concussions to becoming a leading expert in concussion recovery. She challenges the outdated "rest in a dark room" advice and explains why persistent post-concussion syndrome requires an individualized, integrative approach combining neuroscience, functional neurology, and holistic therapies.Timestamps0:10 - IntroductionWelcome and episode overview1:00 - Guest IntroductionMeet Dr. Ayla Wolf - clinician, researcher, and author2:51 - Dr. Wolf's Personal StoryHow multiple concussions changed her career path7:31 - The Turning PointMaking the radical decision to return to school and study brain injuries8:41 - What Happens After a ConcussionUnderstanding the brain's metabolic crisis and energy deficit19:32 - Understanding Functional NeurologyHow this approach differs from traditional assessments25:23 - Acupuncture and Cerebral Blood FlowThe role of holistic therapies in concussion recovery28:34 - Why Rest Isn't Always BestDebunking the "dark room" myth and understanding gradual return to activity31:56 - Dysautonomia ExplainedThe autonomic nervous system and its role in persistent symptoms43:35 - The Concussion Breakthrough BookA comprehensive guide for those feeling stuck in recovery47:14 - Closing Thoughts & ResourcesHow to learn more and connect with Dr. WolfKey TakeawaysMost concussions heal within weeks, but 30% of people develop persistent symptomsProlonged rest beyond 48-72 hours can create maladaptive neuroplasticityFunctional neurology provides individualized treatment based on comprehensive testingDysautonomia (autonomic nervous system dysfunction) is common after concussionRecovery requires integrative approaches addressing multiple brain systems simultaneouslyAcupuncture can improve cerebral blood flow through the trigeminovascular systemResources MentionedDr. Wolf's website: https://www.lifeafterimpact.com/Book: The Concussion Breakthrough: Discover The Missing Pieces to Recoveryhttps://a.co/d/0bCKi38bPodcast: Life After Impact: The Concussion Recovery Podcasthttps://podcasts.apple.com/us/podcast/life-after-impact-the-concussion-recovery-podcast/id1790456849Organization: Healing Response Acupuncture and Functional Neurologyhttps://www.healingresponseneuro.com/Guest BioDr. Ayla Wolf is an associate professor at the Carrick Institute and founder of Healing Response Acupuncture and Functional Neurology. With over 20 years of experience working with complex neurological cases, she specializes in traumatic brain injury, chronic migraine, dysautonomia, and vestibular disorders. Her work combines neuroscience, functional neurology, and holistic therapies to help patients with persistent post-concussion syndrome.

Episode #43: Rewiring the Dyslexic Brain: How Neuroplasticity Can Transform Reading Struggles with Dr. Rebecca TroyGuest: Dr. Rebecca Troy, EdDEducational neuroscientist, dyslexia expert, and national board certified teacherEpisode Summary:Dyslexia affects millions of children and adults worldwide, but modern neuroscience reveals something hopeful: the brain is remarkably plastic and capable of reorganizing itself when given the right training. In this episode, Dr. Rebecca Troy shares over 20 years of expertise helping struggling readers through neuroplasticity-based interventions.Timestamp Highlights:0:10Introduction to the episode2:16Dr. Troy's personal story and background2:30Family history with dyslexia4:01Overview of Dr. Troy's program for parents4:19Redefining dyslexia: Not a permanent deficit7:03The power of daily 10-15 minute practice at home8:15Shortcomings in traditional reading instruction12:42Early warning signs for parents (ages 3-5)15:08How neuroplasticity rewires the dyslexic brain17:35The emotional impact of reading struggles23:55Next steps for concerned parents25:42Understanding phonemic awareness34:39Final message of hope for struggling readersKey Topics Discussed:What dyslexia really is: an underdevelopment in brain connectivity, not a permanent deficitHow neuroplasticity research shows the brain can rewire itself to read like typical readersEarly warning signs parents should watch for (ages 3-5)Why phonemic awareness is the foundation for reading successThe critical importance of early identification and interventionHow daily 10-15 minute structured practice at home can transform outcomesThe emotional impact of unrecognized reading strugglesDyslexia's common overlap with ADHD (40% of cases) and other conditionsHidden strengths in dyslexic brains: spatial reasoning, creativity, and entrepreneurshipWhy the traditional education system needs to shift its approachKey Takeaways:Dyslexia is not permanentBrain imaging studies show that with targeted training, struggling readers can develop the same neural pathways as typical readersParent-led intervention worksDaily practice at home is more effective than weekly clinical sessions due to increased repetition and lower stressEarly intervention is criticalScreening at ages 3-5 can prevent years of academic struggle and emotional traumaThe crawl-walk-run approachExecutive function and phonemic awareness must be developed before phonics-based reading instructionResources Mentioned:Dr. Troy's dyslexia discovery workshops (monthly screenings)PTO Reconnect Therapy programVisualize - New company using playcraft to develop spatial reasoning and creativity strengths in dyslexic children (launching at South by Southwest)Book mentioned: "Teach Your Child to Read in 100 Easy Lessons"Guest Bio:Dr. Rebecca Troy is an educational neuroscientist with a doctorate in education and a neuroscience research focus on reading disabilities. As a national board certified teacher in early and middle literacy, she's spent over 20 years developing practical, neuroplasticity-based interventions that help struggling readers. Her work has been featured in Psychology Today, Women's Journal, and Voyage New York. Dr. Troy is passionate about equipping parents with tools to support children with learning differences and is currently involved in launching Visualize, a company focused on developing dyslexic strengths through play.Connect with Dr. Rebecca Troy: https://www.drrebeccatroy.comAbout This Podcast:The Neurostimulation Podcast explores the science of the brain, innovative treatments, and practical tools to help people unlock their cognitive and emotional potential. Hosted by Dr. Michael Passmore, psychiatrist and clinical associate professor in the Department of Psychiatry at the University of British Columbia.

From Molecules to Meaning: A Scientist's Journey Through Neuroscience and Ancient Wisdom with Dr. José Ángel Moreno Cabezuelo - #42Episode SummaryIn this fascinating episode, Dr. José Ángel Moreno Cabezuelo—molecular biologist, genetic engineering lead at CyanoCapture, and author of "Heartbeats of Consciousness"—shares his unique journey from studying cyanobacteria to exploring the intersection of neuroscience, ancient philosophy, and human consciousness. This conversation bridges hardcore science with timeless wisdom, offering practical insights for living with greater presence, purpose, and meaning.Show Notes with Timestamps[00:00 - 10:04] Opening & Pre-show conversation (can be trimmed)[10:04 - 01:41] Introduction to the Neurostimulation PodcastWelcome and podcast missionInformation about educational purposes and medical disclaimer[01:51 - 03:25] Introducing Dr. José MorenoBackground in molecular biology and genetic engineering at CyanoCapture, OxfordPublished work in Plant Physiology, Microbiology Spectrum, Current Opinion in MicrobiologyIntroduction to his book "Heartbeats of Consciousness"[03:25 - 08:11] Dr. Moreno's Scientific JourneyWorking with cyanobacteria since 2016The surprising fact: half of Earth's oxygen comes from ocean organisms, not forestsMoving from Spain to the UK to develop genetic engineering toolboxCurrent work producing insulin and other compounds in cyanobacteria[08:11 - 13:27] The Birth of "Heartbeats of Consciousness"The gap between knowing how life works and knowing how to live wellWhy current books force a choice between rigorous science and engaging storytellingCreating a hybrid: fiction with scientific rigorThe heartbeat exercise: feeling the invisible protagonist of life[13:27 - 16:31] The Characters: Fania and PaulaFania's story: trauma, resilience, and becoming "antifragile"Paula's journey: scientific curiosity meets emotional anxietyThe hourglass metaphor for living in the present moment[16:31 - 22:38] Three Transformative Scientific IdeasWe Are Literally Light: Biophotons and brain illumination at death (University of Calgary research)Distributed Intelligence: The "second brain" in our gut (500 million neurons, 80-90% of body's serotonin), the heart's 40,000 neuronsNeuroplasticity: The brain's ability to change at any age[22:38 - 26:17] Pleasure vs. HappinessWhy having more comfort hasn't reduced anxiety and depressionDopamine (pleasure) vs. serotonin (happiness)Ancient wisdom meets modern neuroscienceThe firefly metaphor: we are meant to shine and connect[26:17 - 31:30] The Book's Personal JourneyProcessing the loss of his father through writingThe ten promises (decalogue)Being "unbreakable": protecting inner peace from external circumstances[31:30 - 40:30] Connecting Ancient Wisdom with Modern NeuroscienceBuddhist teachings on suffering and desire (2,500 years old)Stoicism and controlling our responsesTaoist Wu-Wei: flowing with lifeHow neuroscience is confirming ancient philosophical insightsDiscussion of psychedelic-assisted therapy and Ram Dass[40:30 - 43:30] Practical ApplicationsUsing metaphors to make science accessibleThe importance of cold exposure and hormetic stressThe problem with endless phone scrolling and dopamine dysregulationBenefits of handwriting vs. typing for brain connectivity[43:30 - 47:40] Love, Clarity, and ConnectionWhy "love" is taboo in academic/clinical settingsLove as the unifying force in science and lifeClarity as an act of loveEverything is connected: from cyanobacteria to consciousness[47:40 - 49:11] Closing Thoughts & ResourcesFinal reflections on the conversationWhere to find Dr. Moreno's work and bookEncouragement to check out "Heartbeats of Consciousness"Key TakeawaysScience and ancient wisdom are converging on the same truths about human wellbeingWe are literally beings of light (biophotons) with distributed intelligence throughout our bodiesNeuroplasticity means we can change at any age—we're not condemned to be who we've beenHappiness comes from giving and purpose, not from pleasure and consumptionThe present moment (the sand falling through the hourglass) is where our attention belongsResourcesBook: "Heartbeats of Consciousness: A Bridge Between Science, Mind, and Soul"https://www.amazon.ca/Heartbeats-Consciousness-Between-Science-Understanding/dp/1919385908Website: drjoseangelmoreno.comConnect: Links to Dr. Moreno's social media and content in episode descriptionThe Neurostimulation Podcast explores the fascinating world of neuroscience, clinical neurostimulation, and evidence-based interventional mental health. Hosted by Dr. Michael Passmore.

Title:"Thriving with ADHD: Understanding Neurodivergence with Kit Slocum"Show Notes:In this episode, I sit down with Kit Slocum, Neurodiversity Lead and Learning Experience Designer at FLOWN, to explore ADHD, neurodivergence, and what it really means to design work and lives that support attention rather than assault it.Kit brings a unique combination of academic training in behavioral neuroscience, lived experience with ADHD, and years of coaching neurodivergent professionals worldwide. We discuss why distraction isn't a moral failing, how our nervous systems respond to modern overstimulation, and practical tools for regulation and focus.Key Topics:The "life on hard mode" experience of neurodivergenceWhy focus is a nervous system issue, not a willpower problemThe Energy Regulation Matrix tool for managing burnoutShame, masking, and late-stage ADHD diagnosisFinding vocational alignment with neurodivergent traitsThe neurodiversity paradigm vs. the pathology paradigmParallels between ADHD coaching and ketamine-assisted psychotherapyThe power of community in neurodivergent spacesResources Mentioned:FLOWN body doubling platform: flown.comKit's ADHD Mastery Program (6-week gamified course) https://flown.com/adhd-focus-program Energy Regulation Matrix tool https://drive.google.com/file/d/1FIiYB9Nd-LXi-eoMyRxApsRC594MPqwD/view?usp=sharingEnergy Regulation How-To https://drive.google.com/file/d/1VjX6yTaC9ZbBhFW3burM5cu6wwoLeWSQ/view?usp=sharingIkigai diagram for career alignment https://drive.google.com/file/d/1V2FxreSqzYrAYpBr2lM-UKg3xcGkfYOA/view?usp=sharingBook: Quiet: The Power of Introverts by Susan Cain https://a.co/d/fRHtUAhPsychedelic Science Conference (Denver) https://www.psycon.org/event/denver-colorado-2026/Connect with Kit:LinkedIn: Kit SlocumFLOWN: flown.comNext ADHD Mastery Program: March 2026Key Takeaway:Attention isn't about forcing yourself to become something you're not—it's about understanding your nervous system and designing your life accordingly.

Episode TitleFear, Purpose, and the Pursuit of Meaning: An Emergency Medicine Physician's Philosophy on LifeGuestDr. Dana Cowles - Board-certified emergency medicine physician with dual academic background in biology and philosophyEpisode SummaryDr. Dana Cowles shares his unique perspective on fear, trauma, and finding purpose through his experiences in emergency medicine and philosophy. From surviving a traumatic car accident at age 12 to working the front lines in emergency rooms, Dr. Cowles challenges conventional wisdom about happiness and offers a compelling framework for building resilience through purpose rather than comfort.Key Topics DiscussedPersonal Trauma & TransformationSurviving a serious car accident at age 12 that shaped his worldviewHow trauma taught him that helplessness, not fear, is the real enemyThe importance of building skillsets throughout life to face uncertaintyThree Types of FearAnticipatory Fear (the "what ifs") - Requires making a plan and trusting itContemporary Fear (immediate crisis) - Demands slowing down and paying attentionRetrospective Fear (PTSD) - Needs reframing into prospective planningEmergency Medicine InsightsThe reality of ER work vs. TV portrayalsRisk stratification over definitive diagnosisThe mantra: "Aviate, Navigate, Communicate" (borrowed from aviation)Why the only unforgivable mistake is telling someone they're safe when they're notThe Happiness MythHow Freud, Bernays, and modern marketing created the "happiness on demand" cultureWhy the opposite of depression is purpose, not happinessThe historical shift from "worthy life" to "euphoric happiness"How consumer culture exploits our pursuit of happinessWhat People Really NeedSecurity (knowing everything will be okay)Affirmation (knowing you're a good person)Purpose over comfortPhilosophy & MeaningEnergy transformation as life's purpose (potential to kinetic energy)Why building, growing, and developing matters more than tearing downThe importance of having plans for life's uncertaintiesWhy "the only thing to fear is fear itself" is wrongHealthcare & SocietyHow medicine has wrongly treated fear and anxiety as diseasesThe unintended consequences of COVID lockdowns (telling 90% of people they weren't "essential")Concerns about AI replacing human purposeThe importance of maintaining purpose regardless of automationMemorable Quotes"The real enemy is helplessness. We need to build a skillset throughout our lifetime to be able to face helplessness.""The opposite of depression is purpose, and purpose is what keeps you up and going.""Everything in life comes at a cost. You need to know that cost and be willing to pay it, or you're gonna accrue interest.""The only people who are truly fearless are thoughtless or careless.""Stop talking to me about what you're against. I want to know what you're for.""I don't believe in good people or bad people. I believe people do good things and people do bad things."Trigger WarningThis episode contains discussions of trauma, death, violence, and graphic medical situations that some listeners may find disturbing.Resources & LinksDr. Dana Cowles's Website https://cowlesemergencyservices.com/For Healthcare ProfessionalsIf you're a healthcare worker, first responder, or caregiver struggling with unresolved trauma, please reach out for support. You're not alone, and help is available.

From the Dojo to the Bedside: How Martial Arts is Revolutionizing Dementia Care with Ben Couch - Episode #39Guest: Ben Couch, Founder of ElumenEd and Eastern ErgonomicsHost: Dr. Michael Passmore, Clinical Associate Professor, Department of Psychiatry, University of British ColumbiaEpisode Length: ~1 hourEpisode SummaryIn this fascinating conversation, martial artist and healthcare educator Ben Couch shares how 40+ years of martial arts training is transforming dementia care and caregiver safety. Ben discusses his innovative Eastern Ergonomics program, which applies ancient martial arts principles—balance, efficiency, breath, and mindful presence—to patient transfers and caregiving. He also opens up about his personal journey after his mother's Alzheimer's diagnosis and how it deepened his understanding of care.Key Topics DiscussedBen's Background40+ years in martial arts (black belts in 8 disciplines, 7th degree in karate)20+ years as National Director of Training at Watermark Retirement CommunitiesFounded ElumenEd to bring Eastern Ergonomics to healthcare facilities nationwidePersonal experience with mother's Alzheimer's diagnosis in 2022The Problem with Traditional Ergonomics TrainingPatient transfers have been the #1 cause of healthcare worker injuries for decadesTraditional training focuses on "dots" without connecting the transitional movementsAnnual compliance training often fails to create meaningful changeInjuries cost $40,000-$120,000 per nurse to replaceMartial Arts Principles Applied to CaregivingMental Preparation:Posture and breathing as foundation for presence and safetyTaking a pause before each transfer to be fully present"New heart every day" mindset to avoid autopilot modeConnection between body posture and mental statePhysical Techniques:Moving from center of gravity rather than arm strength"Hands always push" principle (using triceps/lats instead of biceps/deltoids)Triangulation of balance—avoiding weak points in stanceSoftness, flow, and minimal effort from Tai Chi and Japanese JujitsuPrinciple-based rather than position-based trainingCommunication and DignityShifting from doing something "to" someone → "for" someone → "with" someoneThe person receiving care is the teacher, guiding the caregiverMaintaining presence and listening, even with advanced dementiaTreating every transfer as a mutual, collaborative experiencePersonal InsightsBen's mother's musical awakening after moving to exceptional memory careThe importance of not accepting that "life is over" after an Alzheimer's diagnosisHow martial arts practice helped Ben manage depressionThe parallel between martial arts training and caregiving excellenceVision for the FutureGoal: Remove transfer injuries from the #1 spot for the first time everReduce turnover and burnout among caregiversFree up budget resources for meaningful resident programsChallenge healthcare assumptions about what's possibleBring more presence and continuous improvement to all aspects of careKey Quotes"Everybody has a plan until you get punched in the face." — Mike Tyson (referenced by Ben about his mother's diagnosis)"In the beginner's mind, there are endless possibilities. In the expert's mind, there are very few." — Shunryu Suzuki"You're not ever gonna be good, but you're gonna be better." — Ben on continuous improvement"The person who we are assisting...is the one who should be teaching us. They teach us their movement and then we respond to that.""It's not over when you get this diagnosis...do we act that way?"Resources MentionedElumenEd — Ben's company offering Eastern Ergonomics trainingEastern Ergonomics — Ben's innovative caregiver training programBook: I Heard There Was a Secret Chord by Daniel Levitin (on music and brain health)Who Should ListenNurses, CNAs, and direct care staffHealthcare administrators and risk managersDementia care professionalsPhysical therapists and occupational therapistsFamily caregiversAnyone interested in innovative approaches to healthcare and injury preventionConnect with Ben Couchhttps://easternergonomics.com/https://www.youtube.com/@elumenEdGet Ben's free eBook that covers some fundamentals of the Eastern Ergonomics program. You can also book a time to talk about the benefits of bringing Eastern Ergonomics to your facility.Subscribe & ShareIf you enjoyed this episode, please subscribe to the Neurostimulation Podcast and share it with colleagues in healthcare, caregiving, or anyone interested in innovative approaches to dementia care.Disclaimer: This podcast is for educational purposes only and is not intended as medical advice or a substitute for professional medical guidance.

The Cave You Fear to Enter - Memory Reconsolidation and Emotional Healing with Dr. Brian Desroches - Episode #38Guest: Dr. Brian Desroches, PhD - Psychotherapist, Author, Clinical CoachRelease Date: January 10, 2026Episode SummaryIn this transformative conversation, Dr. Brian Desroches shares how a personal breakthrough in 2015 fundamentally changed his understanding of emotional healing after more than 20 years of clinical practice. Moving beyond traditional "overcome and manage" approaches, Brian introduces listeners to the neuroscience of memory reconsolidation - a process that allows us to update emotional learnings at the synaptic level rather than simply coping with symptoms.Key Topics DiscussedThe 2015 Paradigm ShiftBrian's 10-year struggle with writing procrastination despite extensive therapyHis breakthrough experience with memory reconsolidation at a workshopHow shame and inadequacy became neurologically linked to writing in his brainThe immediate and lasting transformation that followedUnderstanding Emotional LearningHow the brain acquires implicit emotional knowledge in the first 7 years of lifeWhy these learnings feel true in the present moment even when formed decades agoThe difference between explicit trauma memories and implicit emotional patternsHow the brain's predictive process creates protective but maladaptive behaviorsMemory Reconsolidation ExplainedThe brain as a learning, predicting, and adapting processWhat prediction errors (or "prediction corrections") are and why they matterThe five-step process for creating lasting changeWhy insight alone doesn't lead to transformationReframing Self-SabotageWhy "getting in your own way" is actually your brain protecting youThe car analogy: one foot on gas, one on brakeMoving from "what's wrong with me?" to "what did I learn?"Understanding triggers as protective mechanisms, not character flawsThe Role of CompassionWhy compassion is the gateway to self-loveHolding space for the parts of ourselves that learned to protect usThe grief that often accompanies discovering what's really driving our patternsJoseph Campbell's wisdom: "The cave you fear to enter holds the treasure you seek"Practical ApplicationsWhy you must be in an "activated state" for change to occurHow to identify the real threat your brain is predictingThe importance of embodied experience vs. intellectual understandingNavigating systemic changes when you transformMemorable Quotes"It is not a character flaw. The brain is doing its job that it was designed to do - it just doesn't need to do it anymore because it's doing it based on past history that doesn't exist.""When you touch into an emotional learning, it feels true. The emotional brain doesn't know time. You may have learned that 40 years ago, but when it gets activated today, it feels true today.""The cave you fear to enter holds the treasure that you seek. When you land upon an emotional learning, your thinking brain will judge it as irrational, as illogical. But to your emotional brain, it does make sense."About Dr. Brian DesrochesDr. Brian Desroches has over 30 years of clinical experience as a psychotherapist and holds a PhD in Pastoral Counseling and Psychology. Originally from Windsor, Ontario, he now practices in Seattle, Washington. Beyond his therapy practice, Brian consults with dental professionals worldwide, helping them navigate difficult patient interactions and lead complex organizations. His latest book, Living a Trigger Free Life, translates cutting-edge neuroscience into accessible, practical guidance for lasting emotional transformation.ResourcesBook: Living a Trigger Free Life by Dr. Brian DesrochesWebsite: https://a.co/d/bDgsLtCPractice Location: Seattle, WashingtonRelated Concepts MentionedMemory reconsolidationImplicit vs. explicit memoryEmotional learningEMDR (Eye Movement Desensitization and Reprocessing)Internal Family SystemsNeuroplasticityPrediction error/correctionBilateral auditory stimulationFor CliniciansThis episode offers valuable insights for mental health professionals looking to move beyond symptom management toward root-cause transformation. Dr. Desroches' approach integrates neuroscience research with clinical practice in a way that honors both the science and the deeply human experience of healing.Next Episode: Another exciting journey into the cutting edge of neuroscience, neurostimulation, and interventional mental health.Subscribe to never miss an episode and help us reach more curious minds!

Beyond Chemical Imbalance: New Frontiers in Psychiatry with Dr. Theodore Henderson - #37In this episode of the Neurostimulation Podcast, host Mike welcomes Dr. Theodore Henderson, a pioneering psychiatrist and neuroscientist whose work is reshaping the field of mental health. Dr. Henderson challenges the traditional "chemical imbalance" model of psychiatric disorders, advocating for a more nuanced understanding rooted in neuroimaging, neuroplasticity, and the biology of inflammation.Key Topics Discussed:Dr. Henderson’s Journey: From a background in neurobiology and radiology to psychiatry, and how questioning the status quo led him to innovative treatments.Moving Beyond Chemical Imbalance: Why the serotonin hypothesis is outdated, and how new research points to neuroplasticity and mitochondrial health as central to mental wellness.Neuroimaging and Diagnosis: The role of SPECT scans in identifying brain dysfunction, traumatic brain injury, and differentiating between psychiatric conditions.Infrared Light Therapy (Photobiomodulation): How Dr. Henderson’s research has advanced the use of infrared light to stimulate brain repair, neuroplasticity, and recovery from conditions like depression, chronic fatigue syndrome, and traumatic brain injury.Ketamine and Synergistic Treatments: The science behind ketamine’s effects on neuroplasticity, and how combining it with infrared therapy can yield powerful results.Neuroinflammation and Viral Triggers: Insights into how chronic fatigue, depression, and even some cases of Parkinson’s and Alzheimer’s may be linked to viral infections and neuroinflammation.Long COVID: Dr. Henderson’s approach to treating long COVID symptoms, including fatigue and brain fog, with antiviral therapies and infrared light.Personalized Psychiatry: The importance of moving away from a “cookbook” approach to mental health, and embracing individualized, biomarker-driven diagnostics and treatments.Future Directions: The promise of next-generation transcranial magnetic stimulation (TMS), ongoing research collaborations, and the need for broader access to innovative therapies.Actionable Insights:Clinicians: Consider neuroinflammatory and viral contributions to psychiatric symptoms; basic blood tests and antibody panels can be informative.Patients: There is hope beyond standard medications—emerging therapies may offer new avenues for recovery.Resources:Dr. Henderson’s book: Brighter Days Ahead (link in show notes)Dr. Henderson’s clinic and contact information (link in show notes)Connect with Dr. Henderson:https://neuro-luminance.com/about/https://neuro-luminance.com/brighter-days-ahead/If you’re interested in the future of mental health treatment, from infrared laser therapy to the role of neuroinflammation, this episode is essential listening.

The Neurostimulation Podcast #36: How Adenosine Bridges Rapid Antidepressant Therapies – Insights from Ketamine and ECT ResearchHost: Dr. Michael Passmore, Clinical Associate Professor, UBC PsychiatryEpisode Summary: In this episode, Dr. Passmore explores groundbreaking research revealing how adenosine—a natural brain chemical—may be the key link between two of the fastest-acting antidepressant treatments: ketamine and electroconvulsive therapy (ECT). The discussion covers:The science behind adenosine’s role in mood regulation and how both ketamine and ECT trigger rapid antidepressant effects via adenosine pathways.Key findings from a recent Nature study using mouse models, including the necessity and sufficiency of adenosine A1 and A2A receptors for treatment response.The implications for clinical practice, including the potential impact of caffeine (which blocks adenosine) on treatment outcomes.Why standardizing caffeine intake may be important for patients undergoing ketamine or ECT therapy.The importance of translating preclinical findings into human studies and the need for further research.Key Takeaways:Adenosine may act as a “common language” for rapid antidepressant effects in both ketamine and ECT.Caffeine could potentially interfere with these treatments by blocking adenosine receptors—patients and clinicians should be aware of this variable.The research is preclinical (in mice), but it lays the groundwork for future human studies and smarter, more targeted therapies.Resources & Links:Extended data, figures, and the full research paper are linked in the show notes.For more information, check the episode’s resource section.Disclaimer:This podcast is for educational purposes only and does not constitute medical advice. Always consult your healthcare provider for personal medical guidance.Connect & Share:If you enjoyed this episode, please like, subscribe, and share with friends or colleagues who might benefit. Join the conversation in the comments—your feedback helps shape future episodes!Stay curious, and tune in next time for more insights into neuroscience, clinical neurostimulation, and interventional mental health.Contact:Questions, ideas, or feedback? Leave a comment or reach out via the podcast’s contact channels.

Transforming Mental Health: The Power of Neurostimulation and Innovative Therapies with Sam PetersonIn this episode of the Neurostimulation podcast, host Dr. Michael Passmore interviews Sam Peterson, a former army bomb technician and co-founder of Patriot Power Up, who now leads Mind Spa Denver. Sam shares his personal journey from battling PTSD and traumatic brain injury (TBI) to pioneering innovative mental health therapies. He explains the neurobiology of trauma, the impact of neuroinflammation, and the effectiveness of treatments like Ketamine, transcranial magnetic stimulation (TMS), and hyperbaric oxygen therapy in providing rapid relief and promoting neuroplasticity. The discussion highlights the importance of innovative, individualized approaches to mental health care for veterans, first responders, and trauma survivors, aiming to revolutionize treatment protocols and improve lives.https://www.mindspadenver.com/00:00 Introduction to Sam Peterson and His Mission01:48 Sam's Journey from Battlefield to Mental Health Advocate03:03 Understanding the Neurobiology of Trauma04:39 The Role of Inflammation in Mental Health12:36 Innovative Treatments at Mind Spa Denver22:55 Success Stories and Future Vision27:17 Challenges and Opportunities in Mental Health Care36:13 Conclusion and Final Thoughts

Exploring tACS: Current Research and Future Potentials in NeuropsychiatryIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore hosts Dr. Osama Elyamani, a psychiatrist and neuroscientist. They discuss the emerging applications of transcranial alternating current stimulation (tACS) in psychiatry, including its potential as a research tool and therapeutic intervention. They delve into the science of brain oscillations, the clinical evidence surrounding tACS, and future prospects in the field. Particular attention is given to the distinctions between tACS, TMS, and tDCS, as well as the limitations and safety considerations of these neurostimulation techniques. The conversation also touches on the significance of symptom-based approaches in psychiatric treatment and the potential for tACS to aid in diagnosing and treating disorders like depression and schizophrenia. Dr. Elyamani provides insights into ongoing research, future directions, and offers advice for young researchers entering the field.Dr. Osama Elyamany (PhD) is currently a postdoctoral researcher and resident psychiatrist at the Centre of Psychiatry at Justus Liebig University Giessen.He is working on research projects investigating brain oscillations in psychiatric disorders using EEG and fMRI, aiming to develop targeted therapies through pharmacological substances and neurostimulation techniques like tACS and TMS.Email Address: [email protected]: https://www.ukgm.de/ugm_2/deu/ugi_psy/ugi_psy_team.phpLinkedIn: https://www.linkedin.com/in/osama-elyamany/00:00 Introduction and Guest Welcome01:39 Dr. Elyamani's Background and Research Focus02:54 Understanding Brain Oscillations and tACS07:31 Comparing tACS with Other Neurostimulation Techniques11:12 Potential Therapeutic Applications of tACS20:42 Challenges and Future Directions in tACS Research35:20 Safety and Practicality of tACS41:10 Closing Remarks and Future Outlook

Neurostimulation Podcast – Chapter 8: Stimulation Parameters and Their ReportingHost: Dr. Michael Passmore, Clinical Associate Professor, UBCEpisode Overview: In this episode, Dr. Passmore unpacks Chapter 8 of the "Practical Guide to Transcranial Direct Current Stimulation (tDCS)" textbook, focusing on the critical role of stimulation parameters and the importance of transparent reporting in tDCS research and clinical practice.Key Topics Covered:What are stimulation parameters in tDCS?Electrode size, shape, material, and placement (montage)Current intensity, polarity, and densityDuration and ramping protocolContextual factors (e.g., task during stimulation, number of sessions)Why reporting parameters matters:Ensures reproducibility and comparability of studiesPrevents misinterpretation of results due to hidden variablesBuilds trust and transparency in the fieldChallenges in the parameter space:Vast combinations of settings make standardization difficultInter-individual variability (e.g., skull thickness, brain anatomy) affects outcomesPractical guidelines for reporting:Use standardized coordinate systems for placementReport all relevant details, including tolerability and side effectsTreat parameter reporting as a checklist for every study or clinical reportThe bottom line:Parameters are the "recipe" for tDCSSmall differences can lead to big changes in outcomesTransparent, consistent reporting is essential for scientific progress and patient safetyNotable Quotes:“Without the full recipe, you can’t reproduce the results.”“The details aren’t just technicalities—they are the science.”Next Episode Teaser:A look ahead to Chapter 9: How computational modeling helps make sense of the complex parameter space and moves the field toward personalized dosing.Call to Action:Share the episode with colleagues or anyone interested in neurostimulation.Leave comments, questions, or topic suggestions for future episodes.Thank you for listening to the Neurostimulation Podcast!

Neurostimulation Podcast – Aug 30, 2025Guests: Professor Bernhard Hommel & Professor Lorenza ColzatoHost: Dr. Michael PassmoreEpisode Overview:In this episode, Dr. Passmore is joined by Professors Hommel and Colzato to discuss their recent research on metacontrol—the brain’s ability to balance persistence and flexibility—and how it can be modulated using paired anodal tDCS and methylphenidate. The conversation explores the implications of reducing cortical noise, the significance of the aperiodic EEG exponent, and the potential for individualized, biomarker-guided neurostimulation treatments.Key Topics:Definition and importance of metacontrol in cognitive functionThe spectrum between persistence and flexibility in the brainIndividual variability in cognitive control and its clinical relevanceThe study: combining anodal tDCS over the right inferior frontal cortex with methylphenidateFindings: reduction in cortical noise during task processing, indexed by a rise in the aperiodic EEG exponent (especially at fCZ)Implications for ADHD, OCD, and other disorders affecting attention and cognitive controlThe need for replication and standardization before clinical applicationCultural differences in treatment approaches (pharmacological vs. neurostimulation)The future of personalized, feedback-driven neurostimulation and neurofeedbackTakeaways:Metacontrol is a modifiable brain function, not just an abstract concept.Combined tDCS and methylphenidate can reduce cortical noise during tasks, with the aperiodic exponent as a promising EEG marker.The path to clinical application will require safety, individualization, and further research.Links & Resources:Study in Brain Stimulation Journal:https://www.brainstimjrnl.com/article/S1935-861X(25)00081-6/fulltextAdditional lab content and resources:https://www.bernhard-hommel.eu/enThe Metacontrol Lab YouTube channelhttps://www.youtube.com/@metacontrol-2024Disclaimer:This episode is for educational purposes only and does not constitute medical advice. Do not attempt brain stimulation or drug-device combinations outside of supervised clinical research.Connect:If you enjoyed this episode, please like, subscribe, and leave your questions or comments below. Let us know what topics you’d like to hear about in future episodes!

Show Notes: The Neurostimulation Podcast – Episode #30 with Dr. Jennifer RodgerGuest: Dr. Jennifer Rodger, Professor at the University of Western Australia and Head of the Brain Plasticity Research Group at the Perron InstituteRelease Date: August 2, 2025Episode Overview:In this episode, host Michael Passmore sits down with Dr. Jennifer Rodger, a leading neuroscientist whose lab is pioneering research into the mechanisms and safety of low-intensity, repetitive transcranial magnetic stimulation (rTMS), especially in the developing brain.Dr. Rodger shares her unique journey from biochemistry to neuroscience, her initial skepticism about TMS, and how her team’s animal model research is helping to unravel the effects and potential of rTMS in both clinical and research settings. The conversation covers:The challenges and breakthroughs in miniaturizing TMS coils for animal studiesKey findings from recent studies on rTMS in adolescent mice, including effects on brain plasticity and behaviorThe translational bridge between animal research and human clinical applications, especially for youth and neurodevelopmental disordersThe importance of safety, evidence-based innovation, and publishing negative results in scientific researchThe future of tailored neurostimulation protocols and the need for collaboration across labs and disciplinesKey Takeaways:rTMS shows promise for treating neuropsychiatric conditions in youth, but careful, long-term research is essential to ensure safety and efficacy.Animal models provide valuable insights into the mechanisms and potential risks of neurostimulation, especially during critical developmental windows.Publishing negative results is crucial for scientific progress and helps guide future research directions.The field of neurostimulation is rapidly evolving, with opportunities for more personalized and integrated treatment approaches.Resources & Links:Dr. Rodger’s lab and research group: https://brainplasticitylab.org/ https://www.perroninstitute.org/research/research-groups/jennifer-rodger/https://www.perroninstitute.org/research/our-focus-areas/brain-plasticity/Recent publications and studies discussed:Our first low intensity rTMS paper is:Rodger J, Mo C, Wilks T, Dunlop SA, Sherrard RM. Transcranial pulsed magnetic field stimulation facilitates reorganization of abnormal neural circuits and corrects Behavioral deficits without disrupting normal connectivity. FASEB J. 2012 Apr;26(4):1593-606. https://pubmed.ncbi.nlm.nih.gov/22223750/Description of miniaturised coil design:Tang AD, Lowe AS, Garrett AR, Woodward R, Bennett W, Canty AJ, Garry MI, Hinder MR, Summers JJ, Gersner R, Rotenberg A, Thickbroom G, Walton J, Rodger J. Construction and Evaluation of Rodent-Specific rTMS Coils. Front Neural Circuits. 2016 Jun 30;10:47. https://pubmed.ncbi.nlm.nih.gov/27445702/An exhaustive recent review of low intensity rTMS:Moretti J, Rodger J. A little goes a long way: Neurobiological effects of low intensity rTMS and implications for mechanisms of rTMS. Curr Res Neurobiol. 2022 Feb 23;3:100033. https://pubmed.ncbi.nlm.nih.gov/36685761/The work exploring rTMS and endogenous brain activity:Poh EZ, Green C, Agostinelli L, Penrose-Menz M, Karl AK, Harvey AR, Rodger J. Manipulating the Level of Sensorimotor Stimulation during LI-rTMS Can Improve Visual Circuit Reorganisation in Adult Ephrin-A2A5-/- Mice. Int J Mol Sci. 2022 Feb 22;23(5):2418. https://pubmed.ncbi.nlm.nih.gov/35269561/The recent paper about rTMS in adolescent mice is:Tomar M, Pow JJ, Penrose-Menz MA, Beros JL, Miljevic A, Meloni B, Rodger J. Low intensity rTMS in adolescent mice affects visuomotor behaviour with no impact on visual topography. Brain Stimul. 2025 May-Jun;18(3):965-974. https://pubmed.ncbi.nlm.nih.gov/40306617/NB: All research involving animal models was conducted with institutional research ethics board review and approval. Additional reading on rTMS and neurostimulation: https://www.mayoclinic.org/tests-procedures/transcranial-magnetic-stimulation/about/pac-20384625https://my.clevelandclinic.org/health/treatments/17827-transcranial-magnetic-stimulation-tmsConnect with Us:If you enjoyed this episode, please like, subscribe, and leave a review. Share your questions or comments below, and check out the show notes for links to Dr. Rodger’s work and related resources.Stay tuned for more conversations at the intersection of neuroscience, innovation, and clinical practice!The Neurostimulation Podcast – Exploring the science, therapies, and future of brain health.

Deep Dive into tDCS Methodology: Key Considerations and Protocol DesignsIn this episode of The Neurostimulation Podcast, we review chapter seven of the Practical Guide to Transcranial Direct Current Stimulation (tDCS), which focuses on the methodological considerations for selecting tDCS protocols and devices. We discuss important factors such as electrode size and placement, stimulation intensity and duration, and the timing of tDCS sessions. The episode also covers the decision-making framework for clinicians, population-specific adjustments, and the comparison between clinic-based and home-based device use. The role of behavioral tasks during tDCS and the importance of methodological rigor in tDCS research and clinical practice are emphasized. Listeners are encouraged to understand the crucial elements of proper tDCS setup to ensure effective and replicable results.00:00 Introduction to Chapter Seven Review01:17 Importance of Methodology in tDCS01:57 tDCS Decision Matrix02:44 Defining Research and Therapy Goals03:25 Key Variables in Protocol Design05:11 Standalone vs. Adjunctive tDCS06:16 Population-Specific Considerations07:41 Clinic-Based vs. Home-Based Device Use09:13 Session Frequency and Repetition10:39 Integration with Behavioral Tasks11:15 Final Thoughts and Conclusion

Neurostimulation Podcast – Chapter 6: tDCS Safety – Myths, Evidence, and Best PracticesEpisode Overview:In this episode, host Dr. Michael Passmore explores Chapter 6 of the "Practical Guide to Transcranial Direct Current Stimulation: Principles, Procedures, and Applications." The focus is on the safety of tDCS (transcranial direct current stimulation), addressing common myths, reviewing the latest research, and outlining best practices for both clinical and home use.Key Topics Covered:Introduction to tDCS safety and the framework for evaluationDistinction between adverse events and adverse effectsReview of evidence from over 33,000 tDCS sessions and 1,000+ individualsInsights from animal studies and their relevance to human safetyRisk assessment protocols in both animal and human studiesSafety considerations for vulnerable populations (children, stroke survivors, epilepsy, individuals with implants)Home use of tDCS: evidence, compliance, and telehealth supervisionDebunking common myths about tDCS safety:Myth 1: tDCS hasn’t been tested long enoughMyth 2: tDCS is dangerous for older adultsMyth 3: tDCS can cause permanent brain damageCommon mild side effects and how to prevent themReal-world safety guidelines and recommendations for practitioners and researchersThe importance of ongoing vigilance, ethics, and future directions in tDCS safety researchTakeaway Message:When applied responsibly and following evidence-based protocols, tDCS is one of the safest forms of neuromodulation available today. Home use is safe under supervision, and vulnerable groups can be included with tailored protocols. Ongoing research and monitoring will continue to refine best practices.Resources & Links:"Practical Guide to Transcranial Direct Current Stimulation: Principles, Procedures, and Applications"For questions, comments, or topic suggestions, leave a comment below or reach out via the podcast’s contact page.Connect with Us:Don’t forget to like, subscribe, and leave a review! Share this episode with colleagues, patients, or anyone interested in the science and safety of tDCS.Stay Curious, Stay Informed!

Aging with Independence and Innovation: Jennifer Cain Birkmose on the Future of Senior CareIn this episode of the Neurostimulation Podcast, host Michael Passmore discusses senior care innovations with guest Jennifer Cain Birkmose. Jennifer, a pioneering entrepreneur and global health leader, co-founded Viva Valet, a concierge-style service aimed at helping seniors live independently at home for as long as possible. The platform offers comprehensive services including in-home adjustments, technology integration, and safety checks. The episode touches on Jennifer’s methodologies, such as using ethnographic research and involving seniors in beta testing, to ensure user-friendly design. Additionally, Jennifer shares insights from her role as a UN advisor on aging and technology and emphasizes the importance of respect, agency, and social connections in senior care. The conversation concludes with a vision for the future of aging, highlighting the expected societal shifts as the senior population grows.Check out Jennifer's senior's care & support services at Viva Valet https://www.vivavalet.com00:00 Introduction to the Neurostimulation Podcast01:38 Meet Jennifer Cain Birkmose: Innovator in Senior Services04:26 The Viva Valet Platform: Revolutionizing Senior Independence06:25 Challenges and Solutions in Senior Care11:16 User Experience and Technology Integration27:00 Combating Fraud and Ensuring Safety for Seniors33:55 Global Advocacy and Future Directions38:24 Understanding Customer Needs and Bridging Gaps38:46 Resources and Initiatives at Viva Valet39:43 Global Aging and Cultural Commonalities40:24 The Importance of Agency and Independence44:04 Aging with Reverence and Play45:19 Improv and Its Impact on Older Adults54:48 Future Predictions for Aging by 203501:01:55 Closing Remarks and Final Thoughts01:08:13 Podcast Outro and Call to Action

Understanding tDCS: Neurophysiological Insights and Clinical Applications | Neurostimulation PodcastIn this episode of the Neurostimulation Podcast, hosted by Michael Passmore, we delve into Chapter 5 of the 'Practical Guide to Transcranial Direct Current Stimulation.' The episode explores how tDCS modulates neurophysiological and functional outcomes. We discuss the neurophysiological principles behind tDCS, including various methods like TMS, EEG, fMRI, and PET for measuring its effects. The importance of state-dependent neuromodulation and personalized treatment through computational modeling is also highlighted. Finally, the episode examines the clinical implications of tDCS in conditions like stroke recovery, depression, and Alzheimer's disease. Tune in to understand how tDCS is shaping neuroscience and clinical practices.00:00 Introduction to the Neurostimulation Podcast00:47 Exploring Chapter Five of the tDCS Textbook01:52 Understanding Neurophysiological Outcomes02:34 Tools for Measuring tDCS Effects03:41 Regional and Network Effects of tDCS05:16 State-Dependent Neuromodulation06:36 Modeling and Personalized Treatment07:23 Connecting Brain Changes to Behavior08:19 Challenges and Clinical Implications09:07 Conclusion and Future Directions

Exploring Advanced Applications of tDCS: Beyond the BrainIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore continues exploring transcranial direct current stimulation (tDCS) based on 'The Practical Guide to Transcranial Direct Current Stimulation.' He discusses the expansion of DC-based neuromodulation beyond traditional brain applications to the spinal cord and cerebellum. The episode covers three primary targets of DC stimulation: tDCS, cerebellar DC stimulation, and transcutaneous spinal DC stimulation (tsDCS). Additionally, Dr. Passmore delves into electrode setup, clinical applications, home-based treatments, and the challenges and future directions of this evolving field. Tune in to learn about the potential transformative impacts of these techniques on neurological and psychiatric care.00:00 Introduction to the Neurostimulation Podcast01:17 Exploring DC-Based Neuromodulation02:34 Understanding Electrode Design and Placement03:27 tDCS: The Most Researched Form of DC Neurostimulation04:14 Cerebellar DC Stimulation: Beyond Motor Control06:07 Spinal Cord Stimulation: tsDCS Applications07:08 Home-Based Applications and Safety Considerations08:11 Clinical Applications and Case Highlights09:05 Challenges and Future Directions in DC Neuromodulation11:04 Conclusion and Final Thoughts

Exploring Deep Brain Stimulation & Cognitive Function with Dr. David Blake | Neurostimulation PodcastJoin Michael Passmore, clinical associate professor in Psychiatry at the University of British Columbia, as he hosts Dr. David Blake, professor of neuroscience and regenerative medicine at Augusta University. In this episode, they delve into Dr. Blake's groundbreaking research on deep brain stimulation (DBS) and its effects on aging, cognitive function, and neuroplasticity. They discuss the latest findings presented at the 2025 Brain Stimulation Conference in Kobe, Japan, exploring the impact of DBS on neurotrophic markers in cerebrospinal fluid. This fascinating conversation unravels the potential of DBS in treating age-related cognitive decline, Alzheimer's disease, and broader applications such as Parkinson's disease and other neurocognitive disorders. Tune in to discover how Dr. Blake's interdisciplinary approach could revolutionize neurotherapeutics.Blake Lab: https://www.augusta.edu/mcg/dnrm/faculty/blakelab.phpCortical acetylcholine response to deep brain stimulation of the basal forebrain - Brain Stimulation Jan/Feb 2025 (Open access full text)https://www.brainstimjrnl.com/article/S1935-861X(24)00979-3/fulltextIntermittent stimulation of the basal forebrain improves working memoryin aged nonhuman primates Jan/Feb 2025 (Abstract) https://www.brainstimjrnl.com/article/S1935-861X(24)00735-6/fulltextSynchron: https://synchron.comECoG (Electrocorticography): https://en.wikipedia.org/wiki/Electrocorticography#:~:text=Electrocorticography%20(ECoG)%2C%20a%20type,activity%20from%20the%20cerebral%20cortex.00:00 Introduction to the Neurostimulation Podcast01:11 Sponsor and Guest Introduction01:43 Deep Brain Stimulation Research Overview04:04 Discussion with Dr. David Blake06:27 Dr. Blake's Research and Findings22:10 Future Directions and Applications40:14 Brain-Computer Interfaces and Neuromodulation45:10 Advice for Aspiring Neuroscientists48:54 Conclusion and Farewell

Exploring Remote Neurostimulation in Multiple Sclerosis: A Conversation with Drs. Charvet and PilloniIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore from the University of British Columbia engages with Dr. Leigh Charvet and Dr. Giuseppina Pilloni, who break down their research on remotely supervised transcranial direct current stimulation (RS-tDCS). Their discussion focuses on the feasibility, safety, and real-world applications of home-based neurostimulation treatments for multiple sclerosis (MS), targeting symptoms like fatigue and hand dexterity. They also explore broader implications for the future of personalized and accessible neurorehabilitation and explain the mechanisms and potential of tDCS as a complementary treatment option, extending to areas like depression and addiction. The episode underscores the promise of integrating therapy into the home, providing valuable insights for clinicians, researchers, and individuals living with neurological disorders.NYU Langone Clinical tDCS Service Programhttps://nyulangone.org/care-services/tdcs-program?cid=sem_google&sem_campaign_id=22139905662&sem_ad_group_id=&sem_creative_id=&gad_source=1&gad_campaignid=22139906628&gbraid=0AAAAAC9qk2v7bAhjNaz7bDanP8kgj4JsH&gclid=CjwKCAjwo4rCBhAbEiwAxhJlCTSji-MZmNiT9pziGg86R4hb7Mst8JAEHawsJKYB3-vob28tdL4D0RoC2B0QAvD_BwEClinical Research Study: HRV-Guided tDCS: Integrating a Biomarker for Clinical Utility https://clinicaltrials.med.nyu.edu/clinicaltrial/2591/hrv-guided-tdcs-integrating-biomarker/Clinical Research Study: Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosishttps://clinicaltrials.gov/study/NCT06901687?cond=multiple%20sclerosis%20&intr=tDCS&rank=1NYU Langone’s Neuromodulation Lab https://med.nyu.edu/research/charvet-lab/Publications https://med.nyu.edu/research/charvet-lab/publications00:00 Introduction to the Neurostimulation Podcast02:06 Today's Episode: Remote Supervised tDCS for MS03:38 Meet the Experts: Dr. Charvet and Dr. Pilloni04:24 Dr. Charvet's Journey in Neurostimulation06:18 Dr. Pilloni's Background and Research08:30 The Importance of Remote Neurostimulation11:05 Study Design and Methodology13:11 Results and Implications of the Study21:18 Challenges and Future Directions26:50 Exploring Integrated Markers for Treatment Guidance28:12 The Role of Biomarkers in Depression Studies30:16 Mechanistic Studies and Brain Perfusion Insights33:01 Broad Activation and Neuroplasticity34:09 tDCS as a Complementary Treatment37:09 Challenges and Safety in Home-Based tDCS41:12 Accessibility and Future Directions44:57 Cannabis Use and Neurostimulation47:52 Closing Thoughts and Future Prospects51:12 Final Remarks and Podcast Wrap-Up

Neurostimulation Podcast: Self-Care for Caregivers with Jenny LytleWelcome to the Neurostimulation Podcast! In this episode, we explore the intersection of neuroscience, clinical neurostimulation, and self-care for caregivers. Host Michael welcomes Jenny Lytle, an experienced hospice nurse and author of 'Self-Care Isn't Selfish.' They discuss Jenny's journey to prioritizing self-care, her BECOMING method, and practical tips to avoid burnout. This episode is perfect for healthcare professionals, caregivers, and anyone interested in improving their mental and emotional well-being.https://www.selfcareisntselfish.com/00:00 Introduction to the Neurostimulation Podcast01:44 Meet Jenny Lytle: A Journey of Self-Discovery03:00 The Importance of Self-Care for Caregivers05:18 Balancing Caregiving and Self-Care12:01 The BECOMING Method: Personalized Self-Care18:13 Jenny's Book: Self-Care Isn't Selfish20:43 Personal Reflections and Lessons Learned24:54 Honoring a Loved One's Memory25:12 Balancing Caregiving and Self-Care26:11 Practical Self-Care Tips27:36 The Power of Gratitude29:47 Inspiration from Hospice Care32:08 Faith and Spirituality in Self-Care40:49 The Journey of Becoming45:48 Resources and Final Thoughts48:38 Podcast Conclusion

Deep Dive into Transcranial Direct Current Stimulation (tDCS)In this episode of the Neurostimulation podcast, Dr. Michael Passmore, clinical associate professor from the University of British Columbia, delves into the intricacies of Transcranial Direct Current Stimulation (tDCS). The discussion covers the basic mechanisms of tDCS, its applications in modulating brain function, and the biological underpinnings of its acute and long-term effects. Dr. Passmore explains how tDCS influences neuronal activity, neuroplasticity, and even the microarchitecture of brain tissue. The episode also explores the clinical implications of tDCS, the importance of personalized treatment, and future research directions aiming to improve the precision and effectiveness of this neuromodulation tool.00:00 Introduction to the Neurostimulation Podcast01:32 Exploring tDCS: Basics and Mechanisms03:28 Acute Effects of tDCS04:45 Long-term Effects and Neuroplasticity05:59 Beyond Neurons: Microarchitecture and Network Effects07:27 Personalized Treatment and Clinical Implications08:24 Future Directions and Conclusion09:44 Closing Remarks and Next Episode Teaser

Exploring Cutting-Edge Neurostimulation Techniques with Dr. David PlevinIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore talks with Dr. David Plevin, an accomplished psychiatrist and PhD candidate at the University of Adelaide, about his pioneering work in clinical neurostimulation. They delve into various topics, including transcranial magnetic stimulation (TMS), theta burst TMS, and electroconvulsive therapy (ECT). Dr. Plevin sheds light on his systematic reviews and research on predictors of treatment response in depression, while also sharing his unique insights on addiction psychiatry and personalized medicine. The discussion expands to explore the potential applications of neurostimulation for substance use disorders and its future in both psychiatric and non-psychiatric treatments. Tune in for a thought-provoking conversation that promises both clinical insights and philosophical reflections on the future of brain-based therapies.https://researchers.adelaide.edu.au/profile/david.plevinDr. Plevin et al's Systematic Review https://www.sciencedirect.com/science/article/pii/S3050529124000849https://www.tmsjournal.org/article/S3050-5291(24)00084-9/pdfTrial comparing standard rTMS with TBS at 80% and 120% https://pubmed.ncbi.nlm.nih.gov/34332155/00:00 Introduction to the Neurostimulation Podcast00:34 Meet Dr. David Plevin02:28 The Journey to Psychiatry and Neurostimulation04:03 Personalized Medicine and TMS04:35 The Evolution of TMS and ECT06:02 Exploring Theta Burst Stimulation13:33 Predictors of TMS Response22:13 Combining TMS with Other Treatments35:46 Addiction Psychiatry and Neurostimulation45:07 The Future of TMS and Neurostimulation47:46 Conclusion and Farewell

Understanding Autism with Sam Mitchell: Breaking Stigmas and Advocating for Change | Neurostimulation PodcastJoin us on the Neurostimulation Podcast as host Michael Passmore talks with Sam Mitchell, the inspiring leader of Autism Rocks and Rolls, about breaking the stigma around autism. Diagnosed with autism at the age of four, Sam shares his journey, the motivation behind his platform, and his mission to prove that those on the autism spectrum are not broken and don't need to be fixed. They dive into how society can better support individuals with autism, the importance of structure and routine, and the power of community. Additionally, Sam discusses his podcast, his passion for wrestling, and his plans for the future. This episode is a must-watch for anyone interested in autism advocacy and the incredible potential of individuals on the spectrum.https://autismrocksandrolls.com/00:00 Introduction to the Neurostimulation Podcast01:08 Sponsor and Guest Introduction02:49 Sam Mitchell's Journey with Autism03:58 Understanding Autism Spectrum10:10 Challenges and Stereotypes22:03 Building Community and Advocacy29:47 Future Projects and Closing Remarks

Exploring tDCS: Unveiling the Power of Transcranial Direct Current StimulationWelcome to the Neurostimulation Podcast, hosted by Michael Passmore, clinical associate professor at the University of British Columbia. In this episode, we delve into the world of transcranial direct current stimulation (tDCS) as outlined in chapter two of the 'Practical Guide to Transcranial Direct Current Stimulation.' Learn about the biophysics behind tDCS, its non-invasive nature, and how it affects neuronal activity. We break down the intricate details of how tDCS works, its application, key parameters, and emerging technologies like HD tDCS. We also touch on its historical background, ongoing research, potential clinical applications, and its promising future in mental health, rehabilitation, and more. This episode provides a comprehensive guide for anyone interested in understanding the subtle power and extensive promise of tDCS.00:00 Introduction to the Neurostimulation Podcast02:05 Exploring Transcranial Direct Current Stimulation (tDCS)03:06 The Essence of tDCS: Simplicity with Subtle Power04:58 Understanding the Physics of Electrical Current Flow06:56 Neuronal Polarization and Plasticity08:49 Acutely vs. After Effects of tDCS11:40 Dosing tDCS: Key Parameters13:55 Modeling, Personalization, and HD tDCS15:17 Historical Roots of Electrical Stimulation16:34 Mechanistic Nuances and Open Questions17:41 Real World Potential and Clinical Applications19:21 Conclusion and Recap

Exploring Leadership and Mental Health in Healthcare with Dr. Jessica Tighe | Neurostimulation PodcastIn this episode of the Neurostimulation Podcast, Michael Passmore, a clinical associate professor in the Department of Psychiatry at the University of British Columbia, hosts Dr. Jessica Tighe. Dr. Tighe, an executive coach with a PhD in Psychology, shares her extensive expertise in coaching and leadership, especially in high-stress environments like healthcare. The episode delves into strategies for stress management, team cohesion, servant leadership, and the importance of self-care and mental health. Dr. Tighe also discusses the impact of childhood trauma on healthcare professionals and offers practical advice for fostering a healthy and effective work environment. Join us for this enlightening conversation packed with actionable insights and advice on improving organizational effectiveness and personal well-being.https://www.soulutionsforhealth.com/https://www.facebook.com/profile.php?id=100083854606821https://www.linkedin.com/in/jesseca-tighe-426623141/00:00 Introduction to the Neurostimulation Podcast01:31 Introducing Dr. Jessica Tighe03:05 Dr. Tighe's Journey and Expertise05:04 Challenges in Healthcare Leadership09:14 Balancing Work and Personal Life19:13 Effective Communication and Boundaries28:45 Building Cohesive Teams29:54 Managing Through Text vs. Meetings30:44 Creating Safe Spaces in Healthcare31:08 Leadership and Emotional Support33:11 Mental Health and Childhood Trauma34:20 Personal Growth and Coping Mechanisms42:29 Servant Leadership Defined48:59 Self-Care and Boundaries for Leaders53:01 Conclusion and Final Thoughts

Unraveling the Secrets of Elastin: Its Impact on Health and Aging with Douglas MulhallJoin host Michael Passmore in this episode of the Neurostimulation Podcast as he discusses the fascinating world of elastin with biotech entrepreneur and author Douglas Mulhall. They delve into the importance of elastin fiber in the human body, its role in various health conditions, and how it differs from collagen. Douglas highlights groundbreaking research in elastin therapies aimed at reversing arterial damage, healing wounds, and preventing calcification. This educational podcast aims to provide listeners with a comprehensive introduction to elastin and its critical functions in maintaining vitality and health. Note: This episode is for educational purposes only and not intended as medical advice.Douglas' latest book: https://www.amazon.ca/Discovering-Nature-Longevity-Restoring-targeting/dp/1738926737Douglas' first book: https://www.amazon.ca/Our-Molecular-Future-Nanotechnology-Intelligence/dp/157392992100:00 Introduction to the Neurostimulation Podcast01:34 Meet Douglas Mulhall: Biotech Entrepreneur and Author02:46 Understanding Elastin: A General Introduction05:41 The Role of Elastin in the Human Body13:00 Factors Affecting Elastin Degradation26:17 Innovative Treatments and Research on Elastin38:01 Conclusion and Final Thoughts

Overcoming Traumatic Brain Injury: Insights and Strategies with Kelly TuttleIn this episode of the Neurostimulation podcast, host Michael sits down with Kelly Tuttle, an expert in traumatic brain injury (TBI) and author of 'After the Crash'. Kelly shares her personal journey through TBI, the challenges she faced, and the strategies that helped her heal. She provides valuable insights into symptoms like neuro fatigue, light and sound sensitivity, and the importance of holistic care involving sleep, nutrition, and mindfulness. Kelly also emphasizes the significance of journaling for symptom management and offers practical advice on how patients can advocate for their own recovery. Tune in to learn about her five pillars of recovery and hear inspiring messages of hope and resilience for anyone suffering from TBI.00:00 Introduction and Guest Welcome00:59 Kelly's Traumatic Brain Injury Journey03:28 Challenges and Symptoms Post-Injury04:36 Path to Recovery and New Career05:29 Writing the Book: After the Crash10:06 Strategies for Healing and Coping13:11 The Importance of Sleep and Other Pillars of Recovery15:27 Invisible Injuries and Social Impacts19:53 Managing Specific TBI Symptoms27:04 Holistic Approach to TBI Recovery27:19 The Puzzle of Healing: Integrating Specialists28:05 The Power of Journaling and Symptom Tracking28:39 Stressless Medical Sheet: A Gift for Listeners30:04 Maximizing Doctor Visits with Preparedness31:47 Messages of Hope and Encouragement34:14 The Role of Creativity in Healing38:46 Managing Pain and Lifestyle Factors42:36 The Importance of Sleep and Mental Health44:06 Behavioral Aspects and Therapy45:06 Where to Find More About Kelly Tuttle

Enhancing Sexual Health Through Neurostimulation and Lifestyle: A Conversation with Dr. Anne TruongIn this episode of the Neurostimulation Podcast, host Dr. Michael Passmore speaks with Dr. Anne Truong, a physician specializing in pain management, sexual health, and longevity. The conversation delves into the importance of sexual health, the societal taboos surrounding it, and how it is intertwined with overall health and wellness. Dr. Truong shares personal insights and professional experiences, emphasizing the role of lifestyle factors such as diet, exercise, sleep, and stress management in improving sexual function. She also explains the concept of biologics and how they can be used to heal and rejuvenate the body. The discussion aims to destigmatize sexual dysfunction and highlight practical ways to optimize health.00:00 Introduction to the Neurostimulation Podcast01:25 Meet Dr. Anne Truong: Expertise and Background02:36 The Importance of Sexual Health03:06 Dr. Truong's Personal Journey and Approach08:52 Four Pillars of Sexual Health24:48 The Role of Biologics in Healing27:41 Conclusion and Final Thoughts

Revolutionizing Neuroscience: An In-Depth Chat with Steven ZellerJoin host Michael Passmore, Clinical Associate Professor at the University of British Columbia, on the Neurostimulation Podcast as he delves into the world of brain-computer interfaces (BCIs) with entrepreneur Steven Zeller. Explore how Zeller's passion for biotech and neuroscience is driving innovations in BCIs, AI, and space exploration. Understand the ethical considerations, FDA regulations, and the future potential of these technologies. Zeller also shares his personal journey, discussing resilience, entrepreneurial challenges, and the mindset needed to achieve success.00:00 Introduction to the Neurostimulation Podcast01:30 Conversation with Stephen Zeller: An Entrepreneur's Journey05:12 The Entrepreneurial Mindset and Overcoming Challenges15:19 Technological Innovations and Future Prospects23:57 Brain-Computer Interfaces: Current State and Future Potential32:08 Exploring Deep Brain Stimulation32:29 Innovative Approaches in Neuroscience33:19 Breakthroughs in Communication for ALS Patients40:53 Ethical Considerations in BCI and AI43:18 The Future of Brain-Computer Interfaces55:06 Resilience in Entrepreneurship01:01:35 Closing Thoughts and Reflections01:02:19 Podcast Outro and Next Steps

Exploring Brain Health and Development with Dr. Rebecca Jackson | The Neurostimulation PodcastWelcome to The Neurostimulation Podcast! Join Michael Passmore, Clinical Associate Professor of Psychiatry at the University of British Columbia, as he welcomes Dr. Rebecca Jackson, an expert in brain function, development, and mental well-being. In this episode, Dr. Jackson shares her journey from childhood fascination with the human body to her work as a chiropractor and neuroscientist. They discuss optimizing brain function, ADHD, and how multisensory stimulation and physical activity can enhance cognitive abilities across all ages. Dr. Jackson emphasizes the power of holistic approaches and the importance of addressing children's development to set them up for adult success. Tune in to learn research-based strategies to improve mood, cognitive function, and support children's development both at home and in school.Dr. Jackson's Amazon book link 'Back on Track: A Practical Guide to Help Kids of All Ages Thrive': https://a.co/d/0p6PWaRDr. Jackson's Brain Balance website: https://www.brainbalancecenters.com/Info about the Crayola study and the connection between creativity and confidence: https://www.prnewswire.com/news-releases/new-crayola-childrens-study-reveals-a-powerful-link-between-creativity-and-confidence-302326950.htmlDr. Jackson's most recent published study from December: Cognitive Outcomes of the At Home Brain Balance Program https://pmc.ncbi.nlm.nih.gov/articles/PMC11731937/00:00 Introduction to the Neurostimulation Podcast01:22 Meet Dr. Rebecca Jackson: Brain Function and Development Expert03:03 Dr. Jackson's Journey into Neuroscience04:55 The Importance of Holistic Approaches in Brain Health08:41 Childhood Development and Brain Health13:04 The Role of Play and Creativity in Development26:20 Nutrition and Brain Health31:55 The Importance of Early Nutrition33:28 Understanding ADHD in Children36:16 Supporting Attention and Focus in the Classroom42:48 Strategies for Parents to Help Children with Homework49:42 Optimizing Brain Health in Adulthood59:45 The Future of Brain Health Programs01:04:16 Conclusion and Resources

Balancing Medicine and Motherhood: Insights from Neonatologist Dr. Susan LandersIn this episode of The Neurostimulation Podcast, host Michael Passmore, Clinical Associate Professor at the University of British Columbia, welcomes Dr. Susan Landers, an experienced neonatologist and author. They discuss Dr. Landers' journey in neonatology, her personal experiences balancing a demanding medical career with motherhood, and her extensive work on physician burnout and stress management. Dr. Landers shares valuable insights on the emotional challenges faced by working mothers, the importance of self-care, and the evolving nature of parenting in today's culture. Tune in for an in-depth conversation about the intimate and intense world of neonatology and practical strategies for preventing burnout.Dr. Landers' Substack Newsletter 'Moms Matter' https://substack.com/@momsmatterDr. Landers' book 'So Many Babies' https://susanlandersmd.com/book/Dr. Landers' LinkedIn page https://www.linkedin.com/in/susan-landersmd/00:00 Introduction to the Neurostimulation Podcast01:30 Meet Dr. Susan Landers: Neonatology Expert03:13 The Challenges and Rewards of Neonatology09:25 Balancing Medicine and Motherhood12:25 The Importance of Support Systems for Working Mothers15:26 The Impact of Social Media on New Mothers21:52 Dr. Landers' Journey: From Burnout to Advocacy30:52 Embracing Imperfection in Parenting32:06 The Importance of Self-Care for Working Mothers34:09 Balancing Work and Family Life38:46 Challenges of Modern Parenting43:22 The Role of Grandparents and Cultural Wisdom48:37 Future Projects and Reflections on Retirement51:48 Conclusion and Final Thoughts

Exploring Integrative Medicine and Neurostimulation with Dr. Tom Ingegno | Neurostimulation PodcastJoin host Michael Passmore in this episode of the Neurostimulation Podcast as he sits down with Dr. Tom Ingegno, an expert in integrative medicine and the owner of Charm City Integrative Health. With over two decades of experience, Dr. Tom shares his journey from aspiring MD to leading a clinic that blends traditional Eastern medicine with modern biohacking techniques. Discover the origins and benefits of acupuncture, cupping therapy, red light therapy, cryotherapy, and more. Delve into the intersection of ancient wisdom and cutting-edge technology, learn about the significance of meditation, and get inspired by the concept of health sovereignty. Whether you're a healthcare professional or a curious listener, this episode is packed with insights on the future of brain health and holistic wellness.Website: https://charmcityintegrative.comPodcast: https://irreverenthealth.com Newest Book: http://thecuppingbook.comInstagram: https://www.instagram.com/ccintegrativeLinkedIn Company Page: https://www.linkedin.com/company/charm-city-integrative-health/00:00 Introduction to the Neurostimulation Podcast01:37 Dr. Tom Ingegno's Journey into Integrative Medicine04:16 The Importance of Patient-Centered Care in Chinese Medicine06:14 Challenges and Benefits of Integrative Health Practices17:21 The Role of AI and Technology in Modern Healthcare38:29 Empowering Patients in Medicine39:49 The Role of Technology in Modern Healthcare42:54 Exploring the Benefits of Cupping44:28 The Historical and Cultural Significance of Cupping52:04 Integrating Ancient Practices with Modern Therapies01:04:23 The Importance of Meditation in Holistic Health01:11:35 Wrapping Up: Resources and Final Thoughts

Exploring Addiction Recovery & Mental Health Biomarkers with Dr. Evelyn HigginsIn this enlightening episode of the Neurostimulation Podcast, Dr. Michael Passmore welcomes Dr. Evelyn Higgins, founder of Wired for Addiction and Wired Biohealth. The discussion delves into Dr. Higgins's diverse career and her focus on addiction recovery and mental health biomarkers. Listeners will gain insights into the importance of personalized medicine, epigenetics, and comprehensive approaches to wellness. Key topics include the biopsychosocial model of addiction, the role of spirituality in recovery, gratitude journaling, and lifestyle strategies to optimize health. Tune in for an engaging and informative conversation aimed at enhancing mental health and well-being.Dr Higgins' website: doctorhiggins.com // office phone number 404-939-4548Wired BioHealth website: wiredbiohealth.com // office phone number 888-841-7099Wired For Addiction website: wiredforaddiction.com // office phone number 888-841-709900:00 Welcome to the Neurostimulation Podcast01:26 Introducing Dr. Evelyn Higgins03:05 Dr. Higgins' Journey into Addiction Recovery06:11 The Complexity of Addiction08:29 The Biopsychosocial Spiritual Model15:31 The Power of Gratitude21:35 Personalized Medicine and Epigenetics34:43 Understanding Biomarkers in Addiction36:59 Holistic Approach to Addiction37:33 Intermittent Fasting and Lifestyle Changes39:55 The Importance of Sleep and Nature41:01 The Classroom of Silence42:06 The Camino Pilgrimage Experience45:44 The Science of Happiness52:44 The Role of Spirituality in Recovery01:02:35 Future of Addiction Treatment01:04:19 How to Connect with Wired for Addiction01:06:33 Closing Remarks and Podcast Outro

Exploring the Mind of a Generalist: Joel Bouchard on Creativity, Psychology, and Community LeadershipIn this episode of the Neurostimulation Podcast, host Michael Passmore welcomes the multifaceted Joel Bouchard. Joel is a doctoral student in psychology, a multi-instrumentalist record producer, author, painter, army veteran, business leader, local government official, and podcaster. They discuss the benefits of being a generalist, the intersection of creativity and psychology, lessons from Joel's time in the military, and much more. Tune in to explore how diverse fields of knowledge can be connected for personal growth and community betterment.00:00 Welcome to the Neurostimulation Podcast01:07 Introducing Joel Bouchard: A Multifaceted Guest02:03 Joel's Diverse Background and Interests05:22 The Advantages of Being a Generalist19:25 The Intersection of Music and Psychology39:20 Creative Problem Solving and Life Balance43:37 Embracing Life's Challenges44:38 Reframing Struggles for Growth46:38 Personal Academic Journey48:50 Exploring Doctoral Studies55:14 Community Leadership and Volunteering01:05:24 The Philosophy Podcast Journey01:10:36 The Future of Long-Form Conversations01:16:58 Advice for Aspiring Generalists01:20:25 Conclusion and Final ThoughtsJoel's podcast: https://jbouchard.podbean.comJoel's book: https://a.co/d/fYFYifHJoel's music: https://joelbouchardmusic.com

Introduction to Transcranial Direct Current Stimulation (tDCS) | Neurostimulation PodcastWelcome to the Neurostimulation Podcast hosted by Michael Passmore, Clinical Associate Professor in the Department of Psychiatry at the University of British Columbia. This episode serves as the introductory lecture of a comprehensive course on transcranial direct current stimulation (tDCS). We delve into the basics, historical development, clinical applications, and future potential of tDCS. Learn how tDCS fits within the broader landscape of neurostimulation techniques and its advantages and limitations compared to other methods. Ideal for researchers, clinicians, students, and anyone interested in optimizing brain health. Explore the biophysical principles and practical applications of tDCS for mental health, chronic pain, cognitive enhancement, and more. Stay tuned for more in-depth discussions in upcoming lectures. Don't forget to like, subscribe, and join the community interested in the cutting-edge field of neurostimulation.00:00 Welcome to the Neurostimulation Podcast01:10 Introduction to Transcranial Direct Current Stimulation (tDCS)03:03 Foundational Concepts and Applications of tDCS06:24 Understanding Neurostimulation and Neuromodulation11:23 Historical Development of tDCS16:28 Modern Applications and Techniques of tDCS26:31 Current and Emerging Applications of tDCS33:11 Conclusion and Next StepsLecture 1 slideshow available here: https://www.canva.com/design/DAGdPFE_Ilk/uMSBR1FbRRXpps9q3532IQ/view?utm_content=DAGdPFE_Ilk&utm_campaign=designshare&utm_medium=link2&utm_source=uniquelinks&utlId=hb2ceb734betDCS resources: Transcranial Direct Current Stimulation: State of the Art 2008Authored by Michael A. Nitsche et al., this article provides an extensive overview of tDCS, including its mechanisms, applications, and safety considerations.https://www.sciencedirect.com/science/article/abs/pii/S1935861X08000405Transcranial DC Stimulation (tDCS): A Tool for Double-Blind Sham-Controlled Clinical Studies in Brain StimulationWritten by Prateek C. Gandiga, Friedhelm C. Hummel, and Leonardo G. Cohen, this paper discusses the methodology for implementing tDCS in clinical research, emphasizing its utility in double-blind studies.https://pubmed.ncbi.nlm.nih.gov/16427357/Transcranial Direct Current Stimulation in Neuropsychiatric Disorders: Clinical Principles and Management” edited by André R. Brunoni, Michael A. Nitsche, and Colleen K. Loo (2021)This comprehensive book provides an in-depth look at the use of tDCS in treating various neuropsychiatric disorders, discussing clinical principles and management strategies. https://link.springer.com/book/10.1007/978-3-030-76136-3Excitability Changes Induced in the Human Motor Cortex by Weak Transcranial Direct Current Stimulation” by Michael A. Nitsche and Walter Paulus (2000)This foundational study explores how weak tDCS can modulate motor cortex excitability, laying the groundwork for subsequent research into its therapeutic applications.https://pmc.ncbi.nlm.nih.gov/articles/PMC2270099/Non-Invasive Brain Stimulation: A New Strategy to Improve Neurorehabilitation After Stroke?Authored by Friedhelm C. Hummel and Leonardo G. Cohen, this article explores the potential of tDCS and other non-invasive brain stimulation techniques in enhancing neurorehabilitation outcomes post-stroke.https://pubmed.ncbi.nlm.nih.gov/16857577/Transcranial Direct Current Stimulation in the Treatment of DepressionThis article reviews the application of tDCS in treating depression, discussing its efficacy and underlying mechanisms.https://www.sciencedirect.com/science/article/pii/S0149763421001433

Embrace Discomfort to Transform Your Life | Neurostimulation Podcast ft. Dr. Axa YoxIn this compelling episode of The Neurostimulation Podcast, we are joined by the inspiring Dr. Axa Yox, a microbiologist and geneticist turned personal transformation expert. Dr. Yox dives deep into her unique approach to personal development, blending rigorous science with human potential. She discusses key concepts from her groundbreaking book, 'Stop Calling It Comfort Zone,' highlighting the importance of rewiring our thoughts and perspectives to foster positive change. Through insightful discussions, Dr. Yox provides practical strategies on how to start your day with positive intentions, understand the biochemical shifts in our bodies, and embrace discomfort as a catalyst for growth. This episode is a treasure trove of wisdom for anyone looking to optimize their health and wellness. Don't miss out on this transformative conversation!Dr. Yox's book Stop Calling it Comfort Zone https://a.co/d/cO8YUhk00:00 Welcome to The Neurostimulation Podcast00:47 Introducing Dr. Axa Yox01:45 The Power of Thoughts and Rewiring the Mind06:40 Understanding Biochemical Shifts and Emotional Control12:00 The Importance of Incremental Changes28:36 Redefining Comfort Zones and Achieving Goals35:31 The Role of Failure and Progress46:36 The Compounding Effect of Positive Actions47:52 The Secret to Inner Balance48:15 Understanding Control and Expectations48:54 The Power of Positive Emotions49:04 Embracing Challenges and Hormetic Stress51:52 Rewiring Your Brain for Positive Habits53:18 The Importance of Consistency01:07:23 The Role of Dopamine and Serotonin01:09:15 Practical Techniques for Overcoming Dark Times01:20:34 Turning Life's Unfairness into an Advantage01:28:18 Conclusion and Final Thoughts

Harnessing Breathwork for Better Sleep and Resilience with Tim ThomasBelow are the links to the Breathwork in Bed app. The app will guide you to sleep with peace and out of bed with power.Links are for Apple/Smart phones & Google/AndroidsApple link: https://apps.apple.com/app/breathwork-in-bed-app/id6575362285Google Link:https://play.google.com/store/apps/details?id=com.breathworkinbed.bibsleepapp20&hl=enwww.breathworkinbed.com.auhttps://www.instagram.com/breathworkinbed/https://www.facebook.com/breathworkinbedThis is the tutorial for the breath of PEACE and POSSIBILITYhttps://drive.google.com/file/d/1QsuCHJ7UcHrwBIVQp9FTrVvgJGbMjRSw/view?usp=sharingIn this episode of the Neurostimulation Podcast, host Michael Passmore interviews Tim Thomas, an Australian Special Forces veteran and mental health advocate. Thomas discusses his transformative journey from military service to developing his Breathwork In Bed program. They explore the neuroscience behind breathwork, its benefits in reducing stress, enhancing sleep, and fostering overall mental health. Thomas shares personal anecdotes and practical breathwork techniques, emphasizing the power of generosity and connection in promoting well-being. Listeners are also offered a free trial of his breathwork app and an exclusive audiobook. Tune in to discover the profound impact of breathwork on mental clarity, physical health, and emotional resilience.00:00 Introduction to the Neurostimulation Podcast00:31 Meet Tim Thomas: From Special Forces to Breathwork Advocate02:02 The Birth of Breathwork in Bed03:34 The Power of Breathwork in High-Stress Situations07:25 Harnessing the Parasympathetic Nervous System18:16 The Importance of Sleep and Connection24:07 Challenges and Misconceptions in Mental Health Treatment32:03 Tim's Breathwork Techniques and Their Impact38:56 Practical Breathwork Exercises50:06 The Power of Nasal Breathing50:59 Breath of Possibility Technique51:39 Breath of Peace Technique53:06 The Importance of Relaxation55:37 The Impact of Three Breaths58:40 Sharing the Healing01:00:07 Research and Data Collection01:06:10 Personal Journey and PTSD01:14:38 Generosity and Self-Mastery01:21:18 Morning Routine and Generosity01:27:38 Conclusion and Final Thoughts

Neurostimulation: New Frontiers in Mental Health TreatmentIn this episode of the Neurostimulation Podcast, host Dr. Michael Passmore, Clinical Associate Professor at the University of British Columbia, delves into a groundbreaking meta-analysis on the efficacy of neurostimulation techniques like TMS and tDCS across various mental disorders. Covering 208 randomized controlled trials, the discussion highlights the potential of these techniques in treating conditions such as generalized anxiety disorder, substance use disorders, obsessive-compulsive disorder, depression, schizophrenia, and PTSD. Passmore breaks down the results, emphasizing the importance of protocol standardization, discusses the implications for clinical practice, and explores future research directions and innovations in neurostimulation. Listeners are encouraged to consider the challenges and opportunities within this evolving field and to stay engaged for upcoming episodes focusing on personalized mental health care.00:00 Welcome to the Neurostimulation Podcast02:52 Introduction to Neurostimulation Techniques07:12 Key Findings from the Meta-Analysis11:06 Clinical Implications and Future Directions17:29 Advanced Evidence-Based Critical Analysis24:18 Summary and Final ThoughtsStudy: https://pubmed.ncbi.nlm.nih.gov/35365806/Resources: Transcranial Direct Current Stimulation (tDCS):Centre for Addiction and Mental Health (CAMH): Provides an overview of tDCS, its applications, and ongoing research into its efficacy for major depressive disorder. https://www.camh.ca/en/your-care/programs-and-services/therapeutic-brain-intervention-serviceWikipedia - Transcranial Direct-Current Stimulation: Offers detailed information on the technique, its mechanisms, clinical applications, and current research findings. https://en.wikipedia.org/wiki/Transcranial_direct-current_stimulationThe Times - Discusses recent research on the efficacy and safety of home-based tDCS devices for treating depression. https://www.thetimes.co.uk/article/electrifying-your-brain-at-home-can-treat-depression-study-finds-btdbjz2ghRepetitive Transcranial Magnetic Stimulation (rTMS):Centre for Addiction and Mental Health (CAMH): Provides an overview of rTMS, its applications, and current research studies focusing on psychiatric conditions such as major depression, obsessive-compulsive disorder, and schizophrenia. https://www.camh.ca/en/health-info/mental-illness-and-addiction-index/repetitive-transcranial-magnetic-stimulationNova Scotia Health: Offers a detailed pamphlet explaining how rTMS works, potential side effects, and what patients can expect during treatment sessions. https://www.nshealth.ca/patient-education-resources/1975Sunnybrook Health Sciences Centre: Discusses the use of rTMS as a treatment for depression, including patient experiences and insights from medical professionals. https://health.sunnybrook.ca/mental-health/rtms-depression-treatment/Mental Health General: Provides an in-depth article on rTMS, covering its mechanisms, effectiveness, and the mental health conditions it may help treat. https://www.mentalhealthgeneral.com/repetitive-transcranial-magnetic-stimulation-everything-you-need-to-know/The Royal’s Institute of Mental Health Research: Features information on their Neuromodulation Research Clinic, which offers personalized rTMS treatments for depression and ongoing research initiatives. https://www.rtmsresearch-ottawa.ca/

Exploring TDCS for Migraine Treatment: An In-Depth Study ReviewIn this episode of the Neurostimulation Podcast, hosted by Dr. Michael Passmore, Clinical Associate Professor from the University of British Columbia, we dive into the world of transcranial direct current stimulation (TDCS) for the treatment of migraine headaches. The episode features a detailed analysis of the study 'Transcranial Direct Current Stimulation for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials' by Hong and colleagues. Key areas covered include the study's methodologies, findings on the efficacy and safety of TDCS, and its potential implications for clinical practice. The episode aims to offer a comprehensive review and critical appraisal of the study, exploring how TDCS might influence future migraine treatments. Listeners are encouraged to engage with the content through social media and to consult their healthcare providers for personalized medical advice.00:00 Introduction to the Neurostimulation Podcast00:55 Podcast Mission and Audience01:14 Evidence-Based Analysis Commitment01:46 Disclaimer and Full Disclosure02:26 Episode Sponsor and Introduction02:55 Exploring TDCS for Migraine Treatment05:12 Overview of the Hong Study10:42 Study Findings and Implications27:26 Critical Appraisal Using PRISMA34:40 Conclusion and Future DirectionsStudy:Hong P, Liu Y, Wei Y, Zhao J, Zhang J, Zhang Q, et al. Transcranial direct current stimulation for migraine: a systematic review and meta-analysis of randomized controlled trials. CNS Neurosci Ther. 2022;28(5):692–701. doi:10.1111/cns.13843.https://pubmed.ncbi.nlm.nih.gov/35437933/tDCS and migraine resources:Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique that has been explored as a potential treatment for migraines. • The Journal of Headache and Pain: This journal features a systematic review titled “Which is the best transcranial direct current stimulation protocol for migraine prevention?” The article critically appraises randomized controlled trials to determine optimal tDCS protocols for migraine prevention. https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-021-01361-0 • Brain Stimulation Journal: An article titled “Long-term prophylactic efficacy of transcranial direct current stimulation in chronic migraine” discusses the effectiveness of tDCS as a preventive treatment for chronic migraine, providing insights into study designs and outcomes. https://www.brainstimjrnl.com/article/S1935-861X%2822%2900040-7/fulltext • The Journal of Head and Face Pain: This publication includes a systematic review on the use of transcranial magnetic stimulation (TMS) and tDCS for headache treatment, offering a comprehensive overview of neuromodulation techniques in managing headache disorders, including migraines. https://www.brainsway.com/wp-content/uploads/2019/09/Stilling_The-Journal-of-Head-and-Face-Pain-2019_TMS_tDCS_Headache_Review.pdf • The Journal of Neurology and Neurorehabilitation Research: A review article titled “The efficacy of tDCS in the treatment of migraine” examines various studies on tDCS application for migraine relief, discussing methodologies, results, and clinical implications. https://www.alliedacademies.org/articles/the-efficacy-of-tdcs-in-the-treatment-of-migraine-a-review.pdf • SpringerLink: The book chapter “Transcranial Direct Current Stimulation” in the publication “Neuromodulation in Headache and Facial Pain Management” provides an in-depth discussion on the application of tDCS in treating migraines, including technical aspects and clinical findings. https://link.springer.com/chapter/10.1007/978-3-030-14121-9_8

Exploring TDCS for Fibromyalgia Pain ReliefIn this episode of the Neurostimulation Podcast, host Michael Passmore, Clinical Associate Professor in the Department of Psychiatry at the University of British Columbia, introduces the podcast's focus on bringing cutting-edge neuroscience research and education to the public. The episode delves into the use of transcranial direct current stimulation (TDCS) as a treatment for chronic pain in fibromyalgia patients. Detailed insights into the systematic review and meta-analysis conducted on existing TDCS studies are provided, along with an exploration of fibromyalgia, its symptoms, and the challenges in treating it. The episode also discusses the methodology, findings, and implications of the research, highlighting both the strengths and limitations. Emphasis is placed on making the science accessible, and caveats are given regarding the educational nature of the podcast and the importance of professional medical guidance.00:00 Welcome to the Neurostimulation Podcast00:18 Introduction to the Podcast and Host00:26 Podcast Mission and Structure01:45 Disclaimer and Ethical Considerations02:26 Episode Sponsor and Disclosure02:57 Introduction to Today's Topic: TDCS and Fibromyalgia03:21 Understanding Fibromyalgia04:17 Challenges in Treating Fibromyalgia05:26 Introduction to TDCS06:13 Study Overview: TDCS for Fibromyalgia06:50 Systematic Review and Meta-Analysis Explained07:58 Study Methodology and Parameters11:58 Key Findings and Implications15:10 Critical Appraisal of the Study19:01 Conclusion and Final ThoughtsStudy: Moshfeghinia R, Shekouh D, Mostafavi S, Hosseinzadeh M, Bahadori AR, Abdollahifard S, et al. The effects of transcranial direct-current stimulation (tDCS) on pain intensity of patients with fibromyalgia: a systematic review and meta-analysis. BMC Neurol. 2023;23(1):395. doi:10.1186/s12883-023-03445-7.https://pubmed.ncbi.nlm.nih.gov/37919664/tDCS and fibromyalgia resources:Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique that has shown promise in alleviating pain associated with fibromyalgia. • Fibromyalgia Support Network (FSN): FSN offers patient education and resources on chronic illnesses like fibromyalgia. Their website provides information on various treatment options, including neuromodulation techniques such as tDCS. https://fibrosupportnetwork.ca/ • International Association for the Study of Pain (IASP): IASP features articles and systematic reviews on pain management strategies. One such article discusses the effects of tDCS on pain intensity in fibromyalgia patients, offering insights into its efficacy. https://www.iasp-pain.org/publications/pain-research-forum/papers-of-the-week/paper/the-effects-of-transcranial-direct-current-stimulation-tdcs-on-pain-intensity-of-patients-with-fibromyalgia-a-systematic-review-and-meta-analysis/ • Fibromyalgia News Today: This platform provides news and articles related to fibromyalgia research and treatments. An article titled “Managing Chronic Pain with Transcranial Direct Stimulation Shows Promise” explores the potential benefits of tDCS for fibromyalgia patients. https://fibromyalgianewstoday.com/2017/04/05/managing-chronic-pain-tdcs-transcranial-direct-current-stimulation/ • Neurology Advisor: An article titled “Can Transcranial Direct Current Stimulation Effectively Treat Fibromyalgia?” discusses recent studies and findings on the use of tDCS in managing fibromyalgia symptoms, providing a clinical perspective on its application. https://www.neurologyadvisor.com/news/transcranial-direct-current-stimulation-effectively-treat-fibromyalgia/

Home-Based tDCS: A Breakthrough in Treating Major Depressive DisorderIn this inaugural episode of the Neurostimulation Podcast, Clinical Associate Professor Michael Passmore from the University of British Columbia explores the fascinating world of neurostimulation, focusing on a cutting-edge study on home-based transcranial direct current stimulation (tDCS) for treating major depressive disorder. The episode covers the significance of tDCS as an accessible and cost-effective treatment, the robust design and findings of the study, and the potential applications and future of this groundbreaking therapy. The episode also critically appraises the study's methodology, results, and clinical significance. Brought to you in partnership with ZipStim Neurostimulation.00:00 Introduction to the Neurostimulation Podcast03:01 Understanding tDCS and Its Importance04:57 The Mechanics of tDCS06:51 Home-Based tDCS: A New Frontier07:59 Study Design and Methodology12:54 Results and Findings18:15 Safety and Feasibility of Home-Based tDCS23:32 Broader Implications and Future Directions28:42 Critical Appraisal of the Study43:09 Conclusion and Final ThoughtsStudy:Woodham RD, Selvaraj S, Lajmi N, Hobday H, Sheehan G, Ghazi-Noori A, et al. Home-based transcranial direct current stimulation treatment for major depressive disorder: a fully remote phase 2 randomized sham-controlled trial. Nat Med. 2024;30(10):2045–54. doi:10.1038/s41591-024-03305-y.https://pubmed.ncbi.nlm.nih.gov/39433921/tDCS and depression resources:Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique that has shown promise in treating depression. • Flow Neuroscience offers a home-based transcranial direct current stimulation (tDCS) headset designed to treat depression. This device delivers gentle electrical currents to stimulate specific brain regions associated with mood regulation. In the UK, Flow’s tDCS headset has gained attention as a non-invasive, medication-free treatment option for individuals with depression.https://www.flowneuroscience.com/ • ZipStim: Specializing in physician-supervised, home-based tDCS treatments, ZipStim provides personalized therapy plans. Their platform emphasizes convenience and accessibility, offering comprehensive information on how home-based tDCS can be integrated into health care.https://www.zipstim.com/ • Neuroelectrics Blog: An article titled “Home-Based tDCS as a Promising Treatment for Depression” discusses the feasibility and safety of home-administered tDCS, highlighting recent pilot studies and their implications for mental health treatment. https://www.neuroelectrics.com/blog/2024/04/02/home-based-tdcs-as-a-promising-treatment-for-depression/ • Mave Health: Their blog post, “tDCS for Depression: Is Home-Based Treatment Effective with Remote Supervision?” explores the effectiveness of home-based tDCS combined with remote supervision, providing insights into recent research findings and practical considerations. https://www.mavehealth.com/ • Neuroscience News: The article “Home-Based Brain Stimulation Shows Promise for Treating Depression” reports on recent studies demonstrating the safety and efficacy of home-based tDCS for individuals with major depressive disorder. https://neurosciencenews.com/home-tdcs-depression-27896/

Exploring Transcranial Temporal Interference Stimulation (tTIS) and Reinforcement LearningIn this episode of the Neurostimulation Podcast, hosted by Dr. Michael Passmore from the University of British Columbia, the focus is on Transcranial Temporal Interference Stimulation (TTIS) and its role in motor learning and reinforcement. The episode explores a study published in Nature Human Behavior which shows how TTIS can either enhance or disrupt motor learning by targeting the striatum, a critical brain region. Key insights include the methodology of using different frequencies of TTIS on healthy young adults, the impact on reinforcement learning, and the potential clinical applications for neurological conditions like Parkinson's disease. The discussion also delves into the ethical considerations and future directions for this promising non-invasive neurostimulation technology.00:00 Welcome to the Neurostimulation Podcast00:36 Introduction to Neurostimulation and Podcast Goals01:43 Disclaimer and Personal Commitment03:06 Today's Topic: Transcranial Temporal Interference Stimulation (TTIS)04:14 Understanding TTIS: Mechanism and Bioengineering06:37 Reinforcement Learning and the Striatum10:04 The Study: Methodology and Experiment Design13:46 Key Findings and Implications16:50 Advanced Critical Appraisal of the Study23:13 Future Directions and Ethical Considerations26:37 Conclusion and Final ThoughtsStudy: Vassiliadis P, Beanato E, Popa T, Windel F, Morishita T, Neufeld E, et al. Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills. Nat Hum Behav. 2024;8(5):566–74. doi:10.1038/s41562-024-01901-z. https://pubmed.ncbi.nlm.nih.gov/38811696/tTIS resources: Transcranial Temporal Interference Stimulation (tTIS) is an emerging non-invasive neuromodulation technique designed to target deep brain regions with precision. • TI Solutions: This company specializes in developing devices and planning tools for temporal interference research. Their website offers detailed information on the science behind tTIS, device descriptions, and recent advancements in the field. https://temporalinterference.com • Brainbox: Brainbox provides an overview of temporal interference, including its principles, applications, and associated products. The site also references key studies and offers insights into the technique’s potential. https://brainbox-neuro.com/techniques/temporal-interference • Frontiers in Human Neuroscience: This journal features articles such as “A mini-review: recent advancements in temporal interference stimulation in modulating brain function and behavior,” which discusses the latest research and findings related to tTIS. https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2023.1266753/full • EPFL News: The École Polytechnique Fédérale de Lausanne (EPFL) has published articles on non-invasive deep brain stimulation techniques, including tTIS, and their applications in enhancing motor learning. https://actu.epfl.ch/news/non-invasive-deep-brain-stimulation-enhances-motor

Exploring Clinical Neurostimulation: Techniques, Applications, and Future TrendsThis episode of the Neurostimulation Podcast, hosted by Dr. Michael Passmore, clinical associate professor at the University of British Columbia, provides an overview of various neurostimulation techniques used in clinical practice. Techniques covered include Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Transcranial Direct Current Stimulation (tDCS), Deep Brain Stimulation (DBS), and Vagus Nerve Stimulation (VNS). The discussion highlights their mechanisms, applications, strengths, limitations, and future trends. The episode aims to make neuroscience research accessible to healthcare professionals, students, and curious individuals, emphasizing evidence-based analysis and the importance of personalized treatment plans.00:00 Welcome to the Neurostimulation Podcast01:05 Introduction and Mission Statement01:33 Disclaimer and Sponsorship02:52 Exploring Neurostimulation Techniques04:54 Electroconvulsive Therapy (ECT)05:49 Transcranial Magnetic Stimulation (TMS)06:44 Transcranial Direct Current Stimulation (TDCS)07:40 Deep Brain Stimulation (DBS)08:35 Vagus Nerve Stimulation (VNS)09:26 Emerging Techniques and Trends10:03 Comparing Neurostimulation Techniques13:52 Clinical Implications and Future Directions17:32 Conclusion and Future Episodes18:46 Closing Remarks and Call to ActionNeurostimulation resources:Websites:National Institute of Neurological Disorders and Stroke (NINDS):Provides detailed information on various neurological conditions treated by neurostimulation, including Parkinson's Disease, epilepsy, and depression. https://www.ninds.nih.govThe Brain Stimulation Journal:An academic journal focused on the science and clinical practice of brain stimulation techniques. Access to abstracts is free, with some articles available for full reading.https://www.journals.elsevier.com/brain-stimulationDana Foundation:Offers resources on brain health and neuroscience education, including articles on neurostimulation techniques.https://www.dana.orgNeuromodulation: Technology at the Neural Interface:Another key journal for professionals interested in the latest research on neurostimulation technologies.https://www.journals.elsevier.com/neuromodulationOnline Courses and Lectures:Coursera - Neuroscience courses:Universities like Johns Hopkins offer courses on neuroscience that touch upon neurostimulation. Courses like "Medical Neuroscience" can provide foundational knowledge.https://www.coursera.org/courses?query=neuroscienceedX - Neurobiology courses:Harvard's "Fundamentals of Neuroscience" or similar courses can dive into brain function and potential therapeutic interventions.https://www.edx.org/search?q=neurobiologyYouTube Channels:Neuroscientifically Challenged: Offers explanations of neuroscience concepts in an accessible manner.https://www.youtube.com/@UCUgZq9PkDp1xaEivtcfJPSg Neuro Transmissions: Focuses on various aspects of neuroscience, including mental health treatments like neurostimulation.https://www.youtube.com/@neurotransmissionsBlogs and Educational Content:Brain Blogger:Regularly features articles on neurostimulation, mental health, and neuroscience research.https://brainblogger.comThe Neuroethics Blog:Discusses ethical considerations in neuroscience, which could be relevant when exploring the ethical dimensions of neurostimulation technologies.https://www.theneuroethicsblog.comProfessional Societies:International Neuromodulation Society:Offers resources, guidelines, and updates on neuromodulation practices, including neurostimulation techniques.https://www.neuromodulation.comSociety for Neuroscience:Provides access to research, educational materials, and professional development in neuroscience.https://www.sfn.org