🧯 No Smoke, Still Fire – Rethinking Lung Cancer in Never-Smokers

🚭 Lung Cancer in Nonsmokers – a hidden epidemic affecting up to 20% of global cases 🌍. Unlike tobacco-related disease, this form often strikes younger, female, and Asian populations, with EGFR and ALK mutations driving tumors 🔬.   Despite low mutation burden and no smoking history, these patients benefit immensely from targeted therapies like osimertinib and lorlatinib 🎯. Yet, there's no USPSTF recommendation for screening in this group 😔.   We must push for awareness, early detection, and precision approaches 🧬. As the review in JAMA (2025) shows, no smoke doesn't mean no risk. 🔗 doi:10.1001/jama.2025.17695   #LungCancer #PrecisionMedicine #Oncology #PublicHealth #JAMA