Plasmalogen Deficiency And Dementia with Dr. Dayan Goodenowe

Cognitive decline is one of the most concerning aspects of aging and is a major cause of morbidity and mortality in the US.  As of 2014 the CDC stated that of those older than 65 years of age, there was an estimated 5.0 million people suffering with dementia. This number is projected to be nearly 14 million by 2060.There are laundry lists of ideas to prevent cognitive decline, however, few really address the root cause.  My guest today Dr. Dayan Goodenowe a neuroscientist and inventor with Prodrome Sciences. I was introduced to Dr. Goodenowe by a mutual colleague and he really struck a chord with me when he told me about plasmalogens. As we discussed dementia and its root causes, he shared how these unique chemicals of the membrane of our brain called plasmalogens can become deficient and that they may be one of the key links to understanding neurodegeneration and cognitive decline. In todays episodes we discuss plasmalogens, what they are, how they are made, how they help with our heart, brain, immune system, and nervous tissue, and how they can be measured and potentially restored. We also explore · How Plasmalogens help people with high risk for Alzheimer's Disease who have the APOe4 gene · How Plasmalogens inter-relate with other aspects of Dementia such as Amyloid Beta · Specific plasmalogens that might help with multiple sclerosis and autism About our guest: Dr. Goodenowe’s research into the biochemical mechanisms of disease started in 1990. His curiosity about the biochemistry of life is as insatiable today as it was 30 years ago. In those 30 years, Dr. Goodenowe invented and developed advanced diagnostic and bioinformatic technologies, designed and manufactured novel and natural biochemical precursors, and identified biochemical prodromes of numerous diseases including Alzheimer’s disease and dementia, Parkinson’s disease, multiple sclerosis, stroke, autism, amyotrophic lateral sclerosis (ALS), multiple system atrophy, schizophrenia, bipolar disorder, depression, and cancers of the colon, pancreas, ovary, breast, lung, kidney, esophagus, liver, stomach, and endometria. At Prodrome Sciences, Dr. Goodenowe is going beyond the diagnosis of disease and has set his sights on figuring out how long the human body can maintain the physical and biological functions of life. You can find more information at www.prodromesciences.com