Polio vac for all London children

Poliomyelitis, London, New York and Israel All children aged 1 to 9 in London to be offered a dose of polio vaccine Last UK case, 1984 8,000 people developed paralysis every year https://www.gov.uk/government/organisations/uk-health-security-agency https://www.gov.uk/government/news/all-children-aged-1-to-9-in-london-to-be-offered-a-dose-of-polio-vaccine Vaccine-derived poliovirus in sewage in north and east London Genetic diversity (RNA virus) Most are vaccine-like virus A few have sufficient mutations to be classified as vaccine derived poliovirus (VDPV2), behaves more like naturally occurring ‘wild’ polio Joint Committee on Vaccination and Immunisation (JCVI) Targeted inactivated polio vaccine (IPV) booster dose, offered to all children between the ages of 1 and 9 in all London boroughs This will ensure a high level of protection from paralysis and help reduce further spread of the virus. The programme will start with the areas affected, where the poliovirus has been detected and vaccination rates are low It’s important all children aged 1 to 9 – even if up to date with their vaccinations – accept this vaccine when offered Beckton sewage treatment works first Now also, Barnet, Brent, Camden, Enfield, Hackney, Haringey, Islington, Waltham Forest A total of 116 PV2 isolates identified in 19 sewage samples Poliomyelitis https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/148141/Green-Book-Chapter-26-Polio-updated-18-January-2013.pdf https://www.cdc.gov/vaccines/vpd/polio/public/index.html An acute illness Follows invasion through the gastro intestinal tract by polio virus Virus replicates in the gut Has a high affinity for nervous tissue Spread occurs via the bloodstream Retrograde axonal transport to the central nervous system Often infection is clinically inapparent Symptoms may range in severity Fever to Headache, Gastrointestinal disturbance, Malaise Stiffness of the neck and back Aseptic meningitis Paralysis. Ratio of inapparent to paralytic infections 1000 to 1 in children 75 to 1 in adults Transmission Contact with the faeces or pharyngeal secretions Polio virus replicates long periods in GI tract Can be excreted for three to six weeks in faeces Can be excreted for two weeks in saliva Incubation period Three to 21 days When the infection was endemic Paralytic disease is caused by naturally occurring ‘wild virus’ Live attenuated vaccine, (OPV – Sabin) Virus retains the potential to revert to a virulent form, that can rarely cause paralytic disease Vaccine-associated paralytic polio (VAPP) VAPP cases can occur rarely where live attenuated vaccines are used OPV not used in UK since 2004 (US, not since 2000) Inactivated polio vaccine (i.m. injected) for routine immunisation tetanus/diphtheria/inactivated polio vaccine diphtheria/tetanus/pertussis/inactivated polio vaccine Recommended at two, three and four months of age, can be given at any stage from two months up to ten years of age Learn more about your ad choices. Visit megaphone.fm/adchoices