EPISODE · Apr 29, 2026 · 4 MIN
Q&A. Should I Take Calcium-D-Glucarate Whilst On HRT Oestrogen?
from Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health · host Joanne Kennedy
Can you take Calcium-D-Glucarate while on HRT estrogen during menopause? In this short Q&A episode of The Histamine Well Podcast, Joanne explores the relationship between estrogen detoxification, hormone replacement therapy (HRT), menopause, gut health, and histamine-related symptoms.Many women are advised to take supplements that support estrogen detox, but is this always the right approach when using bioidentical hormones or estrogen therapy? Joanne explains why Calcium-D-Glucarate may not be beneficial for menopausal women on HRT, how estrogen balance works during menopause, and why understanding your hormone dose matters for symptom relief and long-term wellbeing.This episode also covers: The role of estrogen during menopause and HRT Why over-detoxifying estrogen may worsen symptoms The connection between beta-glucuronidase, the estrobolome, and gut microbiome health Histamine intolerance, hormone imbalance, and menopause symptoms Natural considerations for estrogen metabolism and hormone support Why gut health may be more important than estrogen detox supplements If you're navigating menopause, hormone replacement therapy, estrogen dominance symptoms, histamine intolerance, or gut-related hormone imbalance, this episode offers practical clarity backed by clinical naturopathic insight. Subscribe to The Histamine Well Podcast for expert conversations on histamine intolerance, methylation, gut health, hormones, mold illness, MCAS, menopause, and functional medicine approaches to healing.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!
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Q&A. Should I Take Calcium-D-Glucarate Whilst On HRT Oestrogen?
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