'Regenerative aesthetics': the next-gen of skincare

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • What is regenerative aesthetics? • New data - ageing skin releases inflammatory mediators into the bloodstream • NEW - treatments that stimulate collagen and elastin • Harmonyca – how it goes beyond traditional fillers / bio stimulators • Bio stimulators – an explainer • NEW - devices that stimulate collagen and elastin • Sofwave • Radiofrequency micro-needling • The role of collagen supplements • NEW injectable – polynucleotides – stimulates stem cells • Juvalook – hyaluronic acid and PDLLA – and the eyes • NEW – gene therapy (and early-stage trials) • NEW – stem cell therapy (and products) • Human stem cells skincare versus plant ‘stem cell’ skincare • Growth factors as ‘stem cells’ in plant-based products • Synthetic products • What do human-based stem cell skincare products actually contain? • How many of the treatments are permanent? • What about downtime? • NEW - using exosomes in skincare • Exosomes – an explainer • Studies on exosomes – how they can regenerate skin and hair growth • Exosomes – topical versus injectables • Exosome skincare brands • South Korea – stem cell banking • NEW – how wrinkle relaxers are evolving • NEW – skincare ingredients to look out for • Sunflower sprout extract – how it works • Skincare that changes how a cell behaves • Dr Sophie’s go-to product • NAD+ as a skincare ingredient • How best to biohack your skin • Dr Sophie’s skincare protocols • Skincare with vitamin C and niacinamide • The role of sleep • The treatments Dr Sophie has • Skincare trends • ‘Prejuvenation’ • Body-care • High-performing plant-derived active ingredients • Microbiome-based skincare • Sustainability in skincare – formulations and packaging • Suncare innovations • AI in aesthetics (robots that inject wrinkle relaxers) • How AI can enhance the industry • The importance of human expertise • Neuro-glow (and mental health) Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: First, this is the Harpers Bazaar article that Dr Sophie contributed to: https://www.harpersbazaar.com/uk/beauty/a46114525/2024-beauty-trends/ There are several studies that indicate how ageing skin releases inflammatory mediators into the bloodstream – here’s one example: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082169/ https://drsophieshotter.com/harmonyca-is-this-injectable-the-future-of-fillers/ https://juvelook.uk/ (Dr Sophie later talks about results here with the eye area) https://lenisna.uk/ More on the new types of filler (e.g. PLLA and PCL) here: https://drsophieshotter.com/what-is-a-collagen-stimulating-filler/ https://www.sculptrausa.com/ https://ellanse.com/ https://radiesse.com/how-it-works/ Dr Sophie uses >> https://sofwave.com/ https://inmodemd.com/workstation/morpheus8/ https://candelamedical.com/products/profound/ https://cutera.co.uk/secretRF#:~:text=secrectRF%20%7C%20Non%2DSurgical%20Facial%20Resurfacing%20%7C%20CUTERA (Secret RF) Dr Sophie uses >> https://candelamedical.com/products/matrix/ https://drsophieshotter.com/everything-you-need-to-know-about-polynucleotides/ Dr Sophie uses >> https://www.cromapharma.com/uk/about-croma/press-and-downloads/croma-pharma-further-strengthening-its-portfolio-with-biostimulators/ Studies on exosomes include: https://www.sciencedirect.com/science/article/abs/pii/S1389172323003262 (hair) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296902/ (skin) Dr Sophie uses >> https://aestheticmanagementpartners.com/exo-e/ (EXO-E) Also mentioned > https://en.drsturm.com/exoso-metic-face-serum/ https://morphiya.com/ On sunflower sprout extract >> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622016/#:~:text=The%20sunflower%20seed%20and%20sprout,%2C%20and%20vitamins%20%5B2%5D. Dr Sophie uses >> https://www.revisionskincare.co.uk/products/d-e-j-daily-boosting-serum%E2%84%A2 Dr Sophie uses >> https://nuchido.com/blogs/news/meet-dr-nichola-conlon-the-founder-of-nuchido The Swedish sleep study https://www.bmj.com/content/341/bmj.c6614 Some brands mentioned: https://luna-daily.com/ https://www.biojuve.co.uk/ https://www.laroche-posay.co.uk/ https://go.redirectingat.com/?id=127X618962&url=https%3A%2F%2Fdcypher.me%2F&xs=1&xcust= (Dcypher – AI-powered foundation brand) https://renude.co/ - AI-trained to identify a range of skin concerns The skincare platform https://klira.skin/ offers epigenetic skin typing. The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast. Mentioned in this episode:This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers. Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off. This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot. Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.