Series 2, Episode 7 - Fasting Without Fasting: The Science of Mimio with Dr. Chris Rhodes episode artwork

EPISODE · Jul 8, 2025 · 56 MIN

Series 2, Episode 7 - Fasting Without Fasting: The Science of Mimio with Dr. Chris Rhodes

from Sweaty AF Podcast · host Sweaty AF

In this episode, I sit down with Dr. Chris Rhodes, metabolic scientist and co-founder of Mimio, to explore the next frontier in fasting and longevity. We unpack the real science behind what happens during a fast , from autophagy to inflammation, and how Mimio, a fasting mimetic, is engineered to replicate these profound benefits without requiring prolonged food restriction.Dr. Rhodes explains how Mimio was developed by analyzing blood samples from individuals in extended fasts, identifying key signaling molecules, and recreating their cellular effects in supplement form. We discuss the nuanced differences in fasting responses between men and women, the impact of fasting on cognitive and hormonal health, and how Mimio may help extend the metabolic benefits of shorter fasting windows.Whether you're deep into fasting protocols or new to the concept of metabolic switching, this conversation delivers practical insights and cutting-edge science on how to optimize your biology with or without skipping meals.The physiological phases of fasting and why timing mattersHow Mimio replicates the cellular effects of a 36-hour fastThe role of autophagy, inflammation, and energy metabolismWhy fasting responses vary by sex and hormonal profileCognitive and mood benefits associated with fasting moleculesThe specific ingredients in Mimio and how they workAppetite regulation and satiety improvements observed in studiesSafety, contraindications, and what to know before using fasting mimeticsThe emerging science of metabolic signaling and future directionsFasting has been shown to extend lifespan significantly in animal modelsMimio is designed to capture the cellular benefits of a 36-hour fastDifferent fasting durations trigger distinct metabolic benefitsFasting mimetics can help amplify results from shorter fastsMimio’s ingredients are selected for their anti-inflammatory and regenerative propertiesUsers have reported cognitive clarity and improved focus with MimioFemale fasting responses may vary due to menstrual cycle phases and hormone fluctuationsFasting supports metabolic health and reduces chronic inflammationClinical research shows Mimio improves appetite control and feelings of satietyOngoing studies aim to expand the fasting mimetic category with new compoundsIf you’re serious about enhancing your healthspan, curious about fasting, and want your cells to perform optimally as you age, this clinically proven supplement is the ultimate biohack for you. Visit mimiohealth.com/sweatyaf and use code SWEATYAF for 20% off your first order of Mimio’s Biomimetic Cell Care supplement.

In this episode, I sit down with Dr. Chris Rhodes, metabolic scientist and co-founder of Mimio, to explore the next frontier in fasting and longevity. We unpack the real science behind what happens during a fast , from autophagy to inflammation, and how Mimio, a fasting mimetic, is engineered to replicate these profound benefits without requiring prolonged food restriction.Dr. Rhodes explains how Mimio was developed by analyzing blood samples from individuals in extended fasts, identifying key signaling molecules, and recreating their cellular effects in supplement form. We discuss the nuanced differences in fasting responses between men and women, the impact of fasting on cognitive and hormonal health, and how Mimio may help extend the metabolic benefits of shorter fasting windows.Whether you're deep into fasting protocols or new to the concept of metabolic switching, this conversation delivers practical insights and cutting-edge science on how to optimize your biology with or without skipping meals.The physiological phases of fasting and why timing mattersHow Mimio replicates the cellular effects of a 36-hour fastThe role of autophagy, inflammation, and energy metabolismWhy fasting responses vary by sex and hormonal profileCognitive and mood benefits associated with fasting moleculesThe specific ingredients in Mimio and how they workAppetite regulation and satiety improvements observed in studiesSafety, contraindications, and what to know before using fasting mimeticsThe emerging science of metabolic signaling and future directionsFasting has been shown to extend lifespan significantly in animal modelsMimio is designed to capture the cellular benefits of a 36-hour fastDifferent fasting durations trigger distinct metabolic benefitsFasting mimetics can help amplify results from shorter fastsMimio’s ingredients are selected for their anti-inflammatory and regenerative propertiesUsers have reported cognitive clarity and improved focus with MimioFemale fasting responses may vary due to menstrual cycle phases and hormone fluctuationsFasting supports metabolic health and reduces chronic inflammationClinical research shows Mimio improves appetite control and feelings of satietyOngoing studies aim to expand the fasting mimetic category with new compoundsIf you’re serious about enhancing your healthspan, curious about fasting, and want your cells to perform optimally as you age, this clinically proven supplement is the ultimate biohack for you. Visit mimiohealth.com/sweatyaf and use code SWEATYAF for 20% off your first order of Mimio’s Biomimetic Cell Care supplement.

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Series 2, Episode 7 - Fasting Without Fasting: The Science of Mimio with Dr. Chris Rhodes

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This episode was published on July 8, 2025.

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In this episode, I sit down with Dr. Chris Rhodes, metabolic scientist and co-founder of Mimio, to explore the next frontier in fasting and longevity. We unpack the real science behind what happens during a fast , from autophagy to inflammation, and...

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