tDCS course Chapter 5 Neurophysiology of tDCS - #27 - June 28, 2025

Understanding tDCS: Neurophysiological Insights and Clinical Applications | Neurostimulation PodcastIn this episode of the Neurostimulation Podcast, hosted by Michael Passmore, we delve into Chapter 5 of the 'Practical Guide to Transcranial Direct Current Stimulation.' The episode explores how tDCS modulates neurophysiological and functional outcomes. We discuss the neurophysiological principles behind tDCS, including various methods like TMS, EEG, fMRI, and PET for measuring its effects. The importance of state-dependent neuromodulation and personalized treatment through computational modeling is also highlighted. Finally, the episode examines the clinical implications of tDCS in conditions like stroke recovery, depression, and Alzheimer's disease. Tune in to understand how tDCS is shaping neuroscience and clinical practices.00:00 Introduction to the Neurostimulation Podcast00:47 Exploring Chapter Five of the tDCS Textbook01:52 Understanding Neurophysiological Outcomes02:34 Tools for Measuring tDCS Effects03:41 Regional and Network Effects of tDCS05:16 State-Dependent Neuromodulation06:36 Modeling and Personalized Treatment07:23 Connecting Brain Changes to Behavior08:19 Challenges and Clinical Implications09:07 Conclusion and Future Directions