EPISODE · Jul 22, 2026 · 38 MIN
The Brain Code: Neuroplasticity, Sleep, and Cognitive Health I The Functional Code Podcast
from The Functional Code Podcast · host Dr. Jace Nybo, Dr. Addy Knutson
Episode 130: Organ Series — BrainYour brain is not fixed.In episode 9 of our Organ Series, Dr. Jace and Dr. Addy break down the brain, neuroplasticity, the glymphatic system, BDNF, memory, Alzheimer’s risk, gut-brain signaling, sleep, exercise, loneliness, meditation, cold exposure, red light therapy, creatine, lion’s mane, and the habits that support long-term cognitive health.The brain uses roughly 20% of the body’s energy despite making up only about 2% of body weight. It is constantly processing, rewiring, adapting, filtering, and responding to the inputs you give it every day.This episode explains the brain as a living computer. Through neuroplasticity, the brain can build and rebuild pathways through repetition, movement, learning, challenge, and experience. Through the glymphatic system, the brain clears metabolic waste during sleep, including waste products associated with Alzheimer’s disease and neurodegeneration.Dr. Jace and Dr. Addy also discuss why cognitive decline can begin years before symptoms appear, why sleep is one of the most important brain health tools, why loneliness can damage the brain, and why exercise may be the most powerful “brain drug” available.In this episode, we cover:The brain as the body’s living computerNeuroplasticity and brain rewiringThe glymphatic system and brain waste clearanceBDNF and building stronger neural connectionsAlzheimer’s disease and early preventionSleep quality and cognitive healthExercise as the best brain drugSocial connection and lonelinessGut-brain signaling and inflammationBlood-brain barrier healthChronic stress, cortisol, and memoryInsulin resistance and Alzheimer’s as type 3 diabetesScreen time, attention, learning, and child developmentNovel experiences, reading, and brain gamesAnti-inflammatory nutrition and omega-3sCreatine and cognitive supportLion’s mane and nerve growth factorCold exposure, norepinephrine, and learningMeditation and brain structure changesRed light therapy and photobiomodulationRed flags: memory changes, mood changes, word-finding issues, getting lost, and wanderingKey takeaway:Your brain changes based on how you use it.The goal is to build a brain that can adapt, learn, recover, clear waste, regulate emotion, and maintain strong communication across the body.Neuroplasticity is the rewiring system.The glymphatic system is the cleaning system.BDNF is the growth signal.And your habits are the inputs.Follow The Functional Code:Instagram: https://www.instagram.com/thefunctionalcodeYouTube: https://www.youtube.com/@TheFunctionalCodeSpotify: https://open.spotify.com/show/3aY5zkhwg5Rzk2q33cbIlfApple Podcasts: https://podcasts.apple.com/us/podcast/the-functional-code-podcast/id1754585557Disclaimer: This podcast is for informational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider.
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The Brain Code: Neuroplasticity, Sleep, and Cognitive Health I The Functional Code Podcast
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