EPISODE · May 25, 2026 · 54 MIN
The Silent Fuel Crisis Starving Your Brain | Dr Stephen Cunnane
from Modern Healthspan · host Modern Healthspan
Discover how the "Brain Energy Gap" drives cognitive decline and how ketones can rescue starving neurons. Dr. Stephen Cunnane explains the science of metabolic health, the BENEFIC trial, and how to fuel a hybrid brain for long-term longevity.Is Alzheimer’s actually a fuel shortage in the brain? In this interview, world-renowned researcher Dr. Stephen Cunnane breaks down the "Brain Energy Gap", a critical metabolic deficit where the brain loses its ability to utilize glucose efficiently as we age. While this energy gap can lead to Mild Cognitive Impairment (MCI) and Alzheimer’s, Dr. Cunnane’s groundbreaking research, including the landmark BENEFIC trial, shows that ketones can bypass this blockage to provide a vital backup fuel source.We dive deep into the hybrid brain concept, exploring how Medium Chain Triglycerides (MCTs) and specific dietary shifts can "rescue" cognitive function by doubling brain ketone uptake. Dr. Cunnane also discusses the "double jeopardy" of insulin resistance and why managing metabolic health is the most promising frontier for preventing neurodegeneration. Whether you are interested in brain health, longevity, or the clinical applications of ketogenic metabolic therapy, this technical deep dive offers essential insights into the future of healthy aging🌐Links in this video A ketogenic drink improves cognition in mild cognitive impairment: Results of a 6‐month RCT https://pmc.ncbi.nlm.nih.gov/articles/PMC8048678/ Improved brain energetics and cognition after a 6-month ketogenic intervention in mild cognitive impairment: Final results of the Benefic Trial https://alz-journals.onlinelibrary.wiley.com/doi/abs/10.1002/alz.037961 A reduced carbohydrate diet improves glycemic regulation in hyperglycemic older people in a retirement home: the SAGE study https://cdnsciencepub.com/doi/10.1139/apnm-2024-0277Time-Line Mitopure Urolithin A, 10% off Code MODERN https://tidd.ly/4bLCpguQitone (10% off: HEALTH10) https://tidd.ly/4jGklry Qitone Esters PowderSeeking Health supplements: 10% discount code Richard10 https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAOAX3 Life Astaxanthin 20% discount code MODERN20 https://tinyurl.com/2t3w26nwhttps://www.choosemuse.comStemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US)Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERNIf you would like to support our channel please consider signing up on patreon https://patreon.com/ModernHealthspanYou can also find us on YouTube at https://www.youtube.com/c/modernhealthspan
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The Silent Fuel Crisis Starving Your Brain | Dr Stephen Cunnane
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