PODCAST · health
Modern Healthspan
by Modern Healthspan
Our channel provides longevity, anti-aging and health information. We interview experts in their field to get the latest information in the longevity space. You can also come to our YouTube channel for more information here https://www.youtube.com/channel/UCLFEKx_LchTLy_XwjPToJ3A
Episodes
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Mitochondrial Doctor: Grey Hair Can Naturally Reverse | Dr. Martin Picard
Dr. Martin Picard, head of the Mitochondrial Psychobiology Laboratory at Columbia University, explains how cellular energy constraints and emotional stress drive biological aging. Discover how psychological allostatic load burns up to 60% more cellular energy, why hair graying is naturally...
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The 40-Year-Old Drug That Slows Your Biological Clock | Dr. John Sedivy
Join Dr. John Sedivy, Director of the Center on the Biology of Aging at Brown University, as he explains how ancient jumping genes (LINE-1 retrotransposons) awaken as our epigenome decays, driving chronic sterile inflammation and cellular aging. Discover how reverse transcriptase inhibitors and...
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3-Drug Combo Extends Lifespan by 41% | Dr. Irina Conboy
Join us as Dr. Irina Conboy, former UC Berkeley professor and Chief Science Officer at Generation Lab, reveals a groundbreaking metabolic senolytic discovery. Learn how combining Dichloroacetate (DCA), Metformin, and a 10-fold lower dose of Navitoclax selectively eliminates senescent and cancer...
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How to Rebuild Bone Density: The Truth About Calcium | Dr Connie Weaver
Join us as Dr. Connie Weaver, Distinguished Research Professor at San Diego State University and National Academy of Medicine member, reveals the hidden science of bone loss, calcium bioavailability, and the gut-bone axis. Discover why fractures kill more people than most realize, why modern...
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A 10-Minute Gene Therapy That Protects You For 10+ Years | Dr Noah Davidsohn
Join us as Dr. Noah Davidsohn, Co-Founder and Chief Scientific Officer of Rejuvenate Bio, reveals how systemic multi-gene therapy and in vivo partial cellular reprogramming can reverse age-related chronic diseases and double remaining lifespan. Discover the breakthrough science of AAV vector...
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The Proven Daily Protocol to Protect Your Memory | Dr. David Perlmutter
In this episode, board-certified neurologist Dr. David Perlmutter, author of Brain Defenders, reveals how your brain’s immune cells, the microglia, hold the key to preventing cognitive decline and neurodegenerative disease. For decades, neurodegenerative research has fixated on amyloid plaques…
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How AI Predicts Your Exact Health 10 Years in Advance | Dr Dmitrii Chebanov
Can AI simulate your exact biology to predict how long you will live? Today we sit down with Dr. Dmitri Chebanov, computational biologist from Memorial Sloan Kettering Cancer Center and Chief Scientist at Holivita, to explore how AI digital twins and multi-omics are turning reactive medicine into...
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He Built a $1.5T Data Giant... Now He's Using AI to Cure Disease | Haresh Patel
Silicon Valley tech entrepreneur Haresh Patel joins Modern Healthspan to reveal how applying systems engineering and artificial intelligence can solve healthcare's chronic diagnostic crisis. After a 55-year struggle across 12 failed medical diagnoses, Haresh founded Sanare Health AI to synthesize...
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How This Peptide Drives Fat Loss & Preserves Muscle | Dr David Lee
USC Gerontology Professor Dr. Changhan David Lee breaks down the discovery of MOTS-c, a novel mitochondrial-derived peptide that functions as an exercise mimetic, cellular stress responder, and immunomodulator. Are mitochondria more than just cellular powerhouses? In this episode of Modern...
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LDL Only Matters IF You Have This One Thing | Dr John Osborne
Discover how AI-guided Cardiac CT scanning detects hidden soft plaque and allows preventive cardiology to track and reverse heart disease before symptoms start Cardiovascular disease remains the leading cause of mortality worldwide, yet over half of affected individuals experience no warning…
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Age-Reversing Stem Cell Treatment Succeeds in Human Trial | Dr Koji Tanabe
Discover how original Yamanaka co-author Dr. Koji Tanabe uses automated iPSC cassettes and autologous stem cell secretomes to reverse cellular aging and repair damaged joints. In this landmark episode of Modern Healthspan, we sit down with Dr. Koji Tanabe, founder and CEO of iPS, Inc. and…
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The NAD Expert: This Is the Ideal Level for Your Cells | Dr Jin Xiong She
Discover the truth about population-wide NAD+ optimization with Dr. Jin-Xiong She from Jinfinity Precision Medicine. We break down the clinical flaws behind the recent Janssen and Houtkooper human blood study claiming NAD levels do not decline with age or lifestyle habits. Learn how ethnicity,...
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Why Your "Healthy" Diet Might Be Making You Sick | Dr Momo Vuyisich
Discover why universally healthy diets don't exist and how metatranscriptomics (RNA sequencing) can track biological aging and reverse chronic disease risk before symptoms start. In this episode of Modern Healthspan, we sit down with Dr. Momo Vuyisich, co-founder of Viome and former lead genomics...
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A Simple Daily Routine That Protects Your Heart | Dr Purnima Kumar
Is your oral health secretly dictating your cardiovascular and metabolic aging? Dr. Purnima Kumar, Chair of Periodontics at the University of Michigan, joins us to explain why the mouth must be integrated back into systemic medicine and how oral dysbiosis accelerates chronic conditions like heart...
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The 10-Minute Biohack That Recharges Your Mitochondria | Dr Alfredo Franco-Obregón
Discover how pulsed electromagnetic field (PEMF) therapy can mimic the systemic benefits of exercise, reverse sarcopenia, and activate mitochondrial health with Dr. Alfredo Franco-Obregón from the National University of Singapore. Learn how "magnetic mitohormesis" stimulates the TRPC1 calcium...
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The Painless Blood Test Outperforming Standard Scans | Dr Tarek Mouhieddine
Discover how advanced blood-based assays and multi-modality screening can identify silent cellular changes before they impact your longevity protocol. Traditional cancer screenings are constrained by structural limitations, capturing less than twenty percent of eventual diagnoses due to strict…
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The Plant Extract That Restores Your Body's Healing Power | Christian Drapeau
Discover how to tap into your body's ultimate internal repair system and unlock the hidden regenerative power of your own stem cells. In this episode of Modern Healthspan, we explore the extraordinary capability of the human body to heal itself from within. Stem cell scientist Christian Drapeau...
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Harvard: The 4-Year Study That Froze Aging For 3 Years | Dr JoAnn Manson
Harvard Professor Dr. JoAnn Manson reveals the final results of the VITAL trial: a landmark study on Vitamin D, telomeres, and disease prevention. Is Vitamin D the most underrated molecule in longevity science? Dr. JoAnn Manson, Professor of Medicine at Harvard Medical School and lead…
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The Silent Fuel Crisis Starving Your Brain | Dr Stephen Cunnane
Discover how the "Brain Energy Gap" drives cognitive decline and how ketones can rescue starving neurons. Dr. Stephen Cunnane explains the science of metabolic health, the BENEFIC trial, and how to fuel a hybrid brain for long-term longevity. Is Alzheimer’s actually a fuel shortage in the brain?…
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The 20-Minute Strength Protocol: Reversing Muscle Loss After 60 | Dr Brad Shoenfeld
Muscle scientist Dr Brad Schoenfeld on how to stay strong after 60. Dr Brad Schoenfeld is a professor of exercise science at Lehman College, New York, and one of the world's most cited researchers on muscle hypertrophy. In this interview we cover the practical science of building and maintaining...
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Should You Take a Multivitamin? A Harvard Researcher’s Verdict | Dr Howard Sesso & Dr Li Sidong
Dr. Howard Sesso of Harvard explains the results of the COSMOS trial, identifying who actually benefits from a daily multivitamin and how it impacts biological aging. Is a daily multivitamin a life-extending "insurance policy" or just a waste of money? In this clip, Dr. Howard Sesso, Co-Principal...
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Beyond Senolytics: Immune Approaches to Senescent Cell Clearance | Dr Amit Sharma
Senescent cells — cells that have stopped dividing but refuse to die — accumulate with age and are increasingly recognised as a key driver of age-related disease. Most people in the longevity space are familiar with senolytics like dasatinib and quercetin, but a potentially more precise approach…
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The Aging Expert Reveals the Top 4 Longevity Molecules | Dr Nir Barzilai
Longevity researcher Nir Barzilai on what centenarians reveal about aging and the four drugs scientists believe may target it directly. Dr Nir Barzilai has spent decades studying people who live to 100 and beyond. What he's found challenges many assumptions about aging, disease, and what we can...
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Targeting Visceral Fat and the Future of Weight-Independent Longevity| Dr. Mikhail Kolonin
GLP-1 drugs likesemaglutide and ozempic have become household names but how much do we reallyunderstand about what they're doing inside the body? In this episode I sit downwith Dr. Mikhail Kolonin, Professor and Director of the Center for Metabolicand Degenerative Diseases at UTHealth Houston's...
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How Urolithin A Boosts Muscle, Immune Function, and Brain Health | Dr. Anurag Singh
Dr. Anurag Singh, Chief Scientific Officer at Timeline Nutrition joins Modern Healthspan for an in-depth conversation about urolithin A and the science of mitophagy, the cellular process that cleans out damaged mitochondria. We explore the clinical evidence from multiple human trials: the ATLAS...
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Why Does Fasting Weaken Cancer But Save Healthy Cells? | Dr Valter Longo
Dr. Valter Longo explains how fasting-mimicking diets make cancer cells vulnerable to treatment while protecting healthy tissue, plus the clinical evidence, safety protocols, and why oncologists remain skeptical. Dr. Valter Longo, author of "Fasting Cancer," breaks down decades of research on…
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Are Mitochondria the Real Driver of Aging? | Dr Luigi Ferrucci
Dr. Luigi Ferrucci reveals what 60 years of Baltimore Longitudinal Study data shows about aging, inflammation, mitochondria, and the biomarkers that predict your health trajectory.In this conversation, Dr. Luigi Ferrucci, Scientific Director of the National Institute on Aging and director of the...
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Creatine for Your Brain: The Dosing Most People Get Wrong | Dr Dan Pardi
Dr. DanPardi explains why creatine supplementation may help preserve cognitivefunction during sleep deprivation, aging, and high mental demand, plus thespecific dosing strategies most people miss. In thisconversation, Dr. Dan Pardi breaks down the emerging science of creatine forbrain health.…
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This Dietary Change Could Save Your Vision | Dr Allen Taylor
Dr. Allen Taylor spent 40 years at Tufts discovering how diet affects vision. Learn why high glycemic foods accelerate macular degeneration and cataracts—and what you can do to protect your eyes. Dr. Allen Taylor directed the Laboratory for Nutrition and Vision Research at Tufts University for…
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Is This The Cause of All Chronic Diseases | Dr Douglas Kell
Your ferritin test doesn't measure what you think. Dr. Douglas Kell explains iron dysregulation, dormant microbes, and his controversial theory about chronic disease Dr. Douglas Kell, systems biologist at the University of Liverpool, presents his research on iron dysregulation and its potential...
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Why Exogenous Ketones Are the Metabolic Game Changer | Dr Eric Plaisance
Dr. Eric Plaisance explains how exogenous ketones may provide fasting benefits without dietary restriction - the hormetic effects of mimicking starvation while fed. Plus: ketone salts vs esters, his personal protocol, and why performance claims don't hold up. Dr. Eric Plaisance, Associate…
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How Coconut Oil Transformed My Husband's Alzheimer's Battle | Dr Mary Newport
Dr. Mary Newport shares groundbreaking research analyzing cholesterol profiles across 40 years of studies, challenging conventional wisdom about saturated fat and heart health. We discuss her findings on MCT oil for brain health, the 288 caregiver reports showing cognitive improvements, and...
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The Truth About Hair Loss & Graying: What Works | Dr Alan Bauman
DESCRIPTION Leading hairrestoration surgeon Dr. Alan Bauman reveals the science behind hair loss,graying, and the evidence-based treatments that actually work—from medicationsto regenerative therapies. Dr. Alan Baumanis a board-certified hair restoration physician who has treated over...
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This Daily Habit Reversed Brain Aging by 10 Years in NIH Study | Dr Henry Mahncke
Dr. Henry Mahncke reveals how an NIH-funded study showed brain training reversed brain aging markers by 10 years, why speed-based training is uniquely effective, and the future of brain health interventions. Dr. Henry Mahncke, CEO of Posit Science and creator of BrainHQ, discusses the...
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At 92 He is Testing a Mitochondrial Transplant That Could Rewrite Aging | Dr John Cramer
Dr. John Cramer, 92-year-old nuclear physicist, discusses participating in the first mitochondrial transplant trial for aging and his longevity theory. Dr. John Cramer is a 92-year-old emeritus professor at the University of Washington who has spent decades researching nuclear physics and quantum...
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The Problem with Senolytics That Clinical Trials Missed | Dr Sundeep Khosla
Mayo Clinic's Dr. Sundeep Khosler discusses findings from the first major randomized controlled trial of senolytics in humans, revealing why cellular aging varies dramatically between individuals and what this means for longevity interventions. Dr. Sundeep Khosler, a physician-researcher at the...
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It is Not Age That Lowers NAD - It is This! | Dr Charles Brenner
Professor Charles Brenner challenges the NAD decline myth and reveals why nicotinamide riboside (NR) works for metabolic stress, not aging. Learn about the Northwestern trial showing NR improved walking speed in peripheral artery disease while metformin failed, eight clinical trials proving...
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The Silent Lipid Deficiency Causing Alzheimer's | Dr Peter Meikle
Could a decline in "plasmalogens" be a missing link in Alzheimer's and aging? Dr. Peter Meikle reveals why this critical brain lipid drops as we age and the surprising foods that might help restore it. In this interview, we sit down with Dr. Peter Meikle, Head of the Metabolomics Laboratory at…
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Human Lifespan Maxes Out At 115 | Dr Jan Vijg
Genetics professor Dr. Jan Vijg explains how DNA damage causes aging and why human lifespan may be limited to 115 years. Learn about the 100,000 DNA hits your cells take daily, breakthrough research on the DREAM gene complex that could slow mutation accumulation, and whether we can extend maximum...
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The Dentist: Your Mouth Predicts Disease 10 Years In Advance | Dr Namrata Patel
Holistic dentist Dr. Namrata Patel reveals how your oral microbiome predicts heart disease, Alzheimer's, and cancer 10-13 years before symptoms appear. Learn about saliva testing, the bacteria that cause systemic inflammation, why tongue exercises reduce sleep apnea 30%, and the daily protocol…
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Why Your Mindset Determines How Well You Age | Dr Lloyd Glauberman
Clinical psychologist Dr. Lloyd Glauberman reveals why smart, motivated people struggle to maintain healthy habits - and the 3 things you knew as an infant that could transform your health. Learn about lifestyle intelligence, the metabolism changes after 40, and why sustaining change is harder…
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Duke Professor: 90-Year-Olds Triple Their Strength In 10 Weeks | Dr William Evans
Duke Professor reveals how 90-year-olds tripled their muscle strength in just 10 weeks - and why we've been measuring muscle mass wrong for decades. Dr. William Evans explains the revolutionary new test that predicts disability, mortality, and even Alzheimer's risk. Learn the exact protocols for...
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The Supplement Scientist: 44% Of Supplements Failed Testing! | Dr Jordan Glenn
44% of supplements FAIL testing! Dr. Glenn, Head of Science at SuppCo, reveals which supplements don't contain what they say, how to spot red flags, and why even expensive brands might be lying about what's in the bottle. Learn the 3 essential rules before buying ANY supplement. Think your...
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The Methylene Blue Expert: Why This Forgotten Medicine Could Save Your Brain | Dr Franciso Gonzalez-Lima
Methylene blue was the first synthetic medicine ever created. 140 years later, we're discovering it might be one of the most powerful tools for brain health and longevity. Here's what the research actually shows. Dr. Francisco Gonzalez-Lima has spent decades researching methylene blue, the first...
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The Hearing Expert – Reducing Dementia Risk By 48%| Dr Ben Thompson
Hearing loss isn't just about your ears—it's about your brain. Dr. Ben Thompson reveals how treating hearing loss can reduce cognitive decline by 48% and shares breakthrough protocols for tinnitus recovery that actually work. Audiologist Dr. Ben Thompson explains the critical connection between...
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The NAD+ Breakthrough: The Secret to Stopping Brain Aging | Dr Evandro Fang
NAD+ Anti-Aging Breakthrough: How This Molecule Could Reverse Aging and Treat Alzheimer's Disease | Clinical Trial Results from Leading Longevity Researcher Dr. Evandro Fang Some links are affiliate links so we will earn a commission when they are used to purchase products. Dr. Evandro Fang from...
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The Alzheimer's Scientist: This $1.50 Supplement Reversed Memory Loss In 8 Weeks | Matthew Taylor
Could a simple supplement that bodybuilders use to build muscle actually help fight Alzheimer's disease? Dr. Matthew Taylor from the University of Kansas reveals surprising results from her groundbreaking clinical trial testing high-dose creatine in Alzheimer's patients In this episode, Dr.…
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This Therapy May Cure AIDS And Extend Your Lifespan | Dr Alessio Lanna
A potential functional cure for HIV could be just months away from human trials. Dr. Lanna reveals how her company Sentcell is using cellular rejuvenation to eliminate HIV reservoirs—and the surprising anti-aging benefits that come with it. n this groundbreaking interview, Dr. Lanna, founder and...
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Groundbreaking New Study Reveals Why Your High LDL May Be Fine | Nick Nowitz, Dave Feldman, Adrian Soto-Mota
When someone's LDL cholesterol hits 574 mg/dL, doctors typically expect the worst. But what if everything we think we know about cholesterol and heart disease risk is incomplete? In this episode, I sit down with researchers Nick Norwitz, Adrian Soto-Mota, and Dave Feldman to discuss their...
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Senescent Cell Expert: Big Pharma Walked Away, But The Future Is Bright | Dr Paul Robbins
Senescent cells were supposed to be the "easy" target in aging research—clear them out and extend healthspan. But new research reveals the field is far more complex than anyone imagined, with major clinical trial setbacks forcing scientists to completely rethink their approach. Some links are...
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ABOUT THIS SHOW
Our channel provides longevity, anti-aging and health information. We interview experts in their field to get the latest information in the longevity space. You can also come to our YouTube channel for more information here https://www.youtube.com/channel/UCLFEKx_LchTLy_XwjPToJ3A
HOSTED BY
Modern Healthspan
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Frequently Asked Questions
How many episodes does Modern Healthspan have?
Modern Healthspan currently has 375 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Modern Healthspan about?
Our channel provides longevity, anti-aging and health information. We interview experts in their field to get the latest information in the longevity space. You can also come to our YouTube channel for more information here https://www.youtube.com/channel/UCLFEKx_LchTLy_XwjPToJ3A
How often does Modern Healthspan release new episodes?
Modern Healthspan publishes regularly with 375 episodes available. Check the episode list for the typical release schedule.
Where can I listen to Modern Healthspan?
You can listen to Modern Healthspan on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Modern Healthspan?
Modern Healthspan is created and hosted by Modern Healthspan.
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