EPISODE · Jun 4, 2026 · 35 MIN
The Truth About Tapering Off GLP-1s with Dr. William Summers
from GLP-1 Hub: Support, Community, and Weight Loss · host Ana Reisdorf, MS, RD
Send us Fan MailMost doctors say GLP-1s are for life. After 12+ years of prescribing Ozempic, Wegovy, and Zepbound, this obesity medicine physician disagrees.Ana Reisdorf, MS, RD sits down with Dr. William Summers, an obesity medicine physician double board-certified in OB/GYN, who has been prescribing GLP-1s for over a decade and runs clinical trials on the next generation of these medications. They cover his actual tapering protocol, why real-world side effect rates run far below what the media reports, the one rare complication every patient needs to spot early, and why he believes we're only at the very beginning of what obesity medicine can do.IN THIS EPISODE- The 9-month tapering protocol for coming off Ozempic, Wegovy, or Zepbound- Why media-reported GLP-1 side effect rates don't match what physicians see in clinic- Pancreatitis on GLP-1 medications — the early warning signs every patient should know- Why some people don't respond to Ozempic or Wegovy (cortisol, leptin, and genetics)- What's coming next: triple receptor agonists, Foundayo, and the future of obesity medicineABOUT THE GUESTDr. William Summers is a practicing physician in Birmingham, AL, board certified in OB/GYN and Obesity Medicine.CONNECT WITH DR. SUMMERSPractice: The Weight Clinic - http://summersweightclinic.com/Video series: Weight Management — A Class With ACT - https://www.youtube.com/@theweightclinic-drsummers SPONSORTyde Wellness — sustainable weight loss with support, for women.https://tydewellness.com/GLP1Hub — use code GLP1HUB50 for $50 off your first monthCHAPTERS00:00 The penicillin of weight loss01:33 Meet Dr. William Summers03:48 Why obesity is a disease, not a behavior06:51 The tapering protocol most doctors don't follow12:51 What the media gets wrong about side effects15:55 Pancreatitis: the one to watch for17:56 Gut impaction, gastroparesis, and constipation20:43 When GLP-1s don't work and why25:54 What's coming next: triple agonists and oral pills31:08 Where to find Dr. SummersMORE FROM GLP-1 HUB📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com📷 Follow on Instagram: @glp1hub📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.
What this episode covers
Send us Fan Mail Most doctors say GLP-1s are for life. After 12+ years of prescribing Ozempic, Wegovy, and Zepbound, this obesity medicine physician disagrees. Ana Reisdorf, MS, RD sits down with Dr. William Summers, an obesity medicine physician double board-certified in OB/GYN, who has been prescribing GLP-1s for over a decade and runs clinical trials on the next generation of these medications. They cover his actual tapering protocol, why real-world side effect rates run far below what th...
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The Truth About Tapering Off GLP-1s with Dr. William Summers
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