Thrombotic Thrombocytopenic Purpura (TTP).

Today, we have a 35 year old African American female with a past medical history of hypertension, who presents to the emergency department. He has a two week history of a viral upper respiratory symptoms, including a low grade fever, cough, nasal congestion, rhinorrhea, sore throat, decreased oral intake - followed by a persistent nose bleed. The nose bleed began over the last couple days and isn't stopping despite persistent pressure. And over the last 24 hours, she had a change in her mental status per her family. Her exam was unremarkable. Her vitals: 100.2 F, HR 90s, BP 145/82, and 98% O2 RA.  Initial labs revealed: WBC: 18,000 H/H: 9/27 Platelets: 7,000 Creatinine: 1.4 Total bilirubin: 3 LDH: 1,500 Normal fibrinogen, D-dimer, PT, INR Peripheral smear: moderate schistocytes What's your diagnosis? Well, at this point, we are thinking Thrombotic thrombocytopenic purpura (TTP). Today, we are going to break this disease down for you. - Our goal at Medgeeks is to help you live the life you want to live as you navigate a career in medicine. This looks different to everyone, which is why we take such a personalized approach.  Whether you want to ... Stop taking your work home Have the skillset to work autonomously Improve your work life balance ...or anything in between, we can definitely help.   We've worked with thousands since 2013 and we're confident we can help take your career and life to the next level. You can learn more about our mentorship opportunities here:   https://www.medgeeksmentorship.co/opportunities   or schedule a time to chat with our advisors here:   https://www.medgeeksmentorship.co/application   - Learn more about what we do here https://medgeeks.co/about-us - Check out our free Facebook group, where we share daily clinical pearls, advice, and practice changing updates: https://www.facebook.com/groups/medgeeks - This podcast should not be used in any legal capacity whatsoever, including but not limited to establishing standard of care in a legal sense or as a basis for expert witness testimony. No guarantee is given regarding the accuracy of any statements or opinions made on the podcast, video, or blog.