TWiV 403: It's not easy being vaccine

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, a new adjuvanted subunit zoster vaccine.   Become a patron of TWiV! Links for this episode Tribunal orders release of PACE trial data (Valerie Eliot Smith) Our request for PACE trial data (virology blog) GM mosquito release on ballot (NPR) Florida Keys Mosquito Control District on TWiV #111 Cold chain and virus free plant based polio vaccine (Plant Biotechnol J) Disappointing flu vaccine effectiveness (CBC) ACIP votes down use of LAIV (CDC) LAIV as effective as inactivated flu vaccine (Ann Int Med) Flumist does work (NPR) Declining effectiveness of zoster vaccine (J Inf Dis) Efficacy of adjuvanted subunit zoster vaccine (NEJM) Risk of zoster from vaccine (J Inf Dis) Image credit: ViralZone Letters read on TWiV 403 This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completel free if you sign up at curiositystream.com/microbe and use the promo code MICROBE. This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100. Weekly Science Picks Alan - To Scale: The Solar SystemRich -  Route 66 Goes SolarVincent - Race for a Zika Vaccine by Siddhartha Mukherjee Listener Picks Bohdan - Penn and Teller on VaccinationsBill - Connections, Episode 1 Send your virology questions and comments to [email protected]