TWiV 409: A Nef is enough

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guest: Jeremy Luban Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles.   Become a patron of TWiV! Links for this episode No recovery in PACE trial (virology blog) The real PACE data (virology blog) Contagious Thinking Florida DOH daily Zika update Congress does not fail on Zika (NPR) Nef history (Luban lab) Nef excludes SERINC from virions (Nature) SERINC counters Nef (Nature) ASM Grant Writing Online Course Letters read on TWiV 409 This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE. 0:25, 28:50 This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100. Weekly Science Picks Alan - Migration in MotionDickson - Beautiful Chemistry Rich - XKCD Timeline of Earth Temperature Kathy -  Vaccine Heroes from Vaccine Education CenterJeremy - CIDRAP posters and Demon in the Freezer Vincent - People Peas and Pathogens Listener Picks Matlock - Science isn't broken Send your virology questions and comments to [email protected]