TWiV 420: Orthogonal vectors

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiV gurus describe how to use an orthogonal translation system to produce infectious but replication-incompetent influenza vaccines.   Become a patron of TWiV! Links for this episode Register for ASV 2017 Local Zika virus transmission in Texas Texaszika.org Local dengue virus transmission in Texas (EID) No more Zika virus transmission in Florida (FL DOH) Dengue virus antibodies enhance Zika virus infection (Clin Trans Imm) Infectious, replication incompetent influenza virus vaccine (Science) Pyrrolysl-tRNA synthetase (Biochem Biophys Acta) History of nonsense suppression (Stan Maloy) Suppression of poliovirus amber mutant (Cell) Remembering mumps (PLoS Path) Letters read on TWiV 420 This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE. Weekly Science Picks Alan - Superbugs game Dickson - Dinosaur tail trapped in amber Rich - Earth's Rotation is Slowing (original article)Kathy - Lithium Ion batteries (one and two) Vincent - Truth and Lies in the Age of Trump (virology blog) and self driving Uber car Listener Pick Steve - New York City Street Tree Map Justin - Transmissible vaccines? Send your virology questions and comments to [email protected]