TWiV 714: The shape of spike with Jason McLellan

Jason McLellan joins TWiV to reveal all we know about the SARS-CoV-2 spike protein, followed by Novavax and J&S phase 3 results and a discussion of variants of concern: neutralization by vaccine-induced antibodies, transmission, and virulence. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Amy Rosenfeld Guest: Jason McLellan Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Prefusion spike structure (Science) Neutralization of VOC by vaccine induced antibodies: Moderna and Pfizer Novavax COVID-19 vaccine phase 3 results (Novavax) J&J COVID-19 vaccine phase 3 results (J&J) B.1.1.7 has been in the US since November 2019 (virological.org) NERVTAG report on B.1.1.7 virulence (pdf) Timestamps by Jolene. Thanks! Weekly Picks Dickson – Pandemic Pivot and Tuba Skinny Alan – Technological challenges in vaccine rollout Rich – I was lucky to find this vaccine anywhere Vincent – Lady Gaga's MIXED METER Star Spangled Banner?! Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]