Two distinct fetal-type signatures characterize JMML - Ep 2.8

In this episode of the HemaSphere podcast, host Charles de Bock engages with Professor Hélène Cavé and Dr. Marion Strullu to discuss their recent study on juvenile myelomonocytic leukemia (JMML). They delve into the complexities of diagnosing JMML, the genetic mutations associated with the disease, and the prognostic factors that influence patient outcomes. The conversation explores the intriguing biology of JMML, including the role of transcriptional signatures and methylation patterns, as well as the challenges faced in sample collection. The episode concludes with insights into future research directions in understanding JMML.  "Two distinct fetal-type signatures characterize JMML" is on our website and all major podcast platforms (Spotify, Apple Podcast + more) and YouTube. Listen and enjoy casual,insightful discussions about #hematology research. You've read the paper, now hear the story.You can find the referenced article, in full and open access, here on the HemaSphere website.

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This episode is 36 minutes long.

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This episode was published on April 2, 2025.

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