Unmuted: Equity in Focus - Rethinking Vulvar Cancer Treatment: The STRIVE Study

Unmuted: Equity in Focus is back with an episode spotlighting the future of personalized care in vulvar cancer. 🎙️💙 Sabrina is joined by Dr. Amy Jamieson, Gynecologic Oncologist at Vancouver General Hospital and BC Cancer, to talk about the STRIVE trial — a newly launched study exploring whether HPV and TP53 status can guide more tailored, less invasive surgical approaches for vulvar squamous cell carcinoma. Dr. Jamieson walks us through why vulvar cancer has been historically understudied, the critical difference between HPV-associated and HPV-independent disease, and why moving beyond a “one-size-fits-all” surgical model could transform outcomes and quality of life for patients. She also discusses the importance of integrating patient-reported outcomes, such as sexual health and fear of recurrence, and what it will take to translate molecular stratification into real-world practice. Tune in for a clear, accessible conversation about why STRIVE matters — and how this trial could shape the next chapter of vulvar cancer care.  Resources:https://ascopubs.org/doi/10.1200/JCO.2025.43.16_suppl.TPS5637  For more information on the Gynecologic Cancer Initiative, please visit https://gynecancerinitiative.ca/ or email us at [email protected]  Where to learn more about us:  Twitter – @GCI_Cluster Instagram – @gynecancerinitiative Facebook – facebook.com/gynecancerinitiativeTikTok – @gci_gosh