Vanessa Rissetto: A CEO’s Honest Take on Nutrition, Mental Health, and Saying What You Mean is great episode artwork

EPISODE · Sep 24, 2025 · 51 MIN

Vanessa Rissetto: A CEO’s Honest Take on Nutrition, Mental Health, and Saying What You Mean is great

from The Big Silence

Have a message for Karena? She'd love to hear from you and share your comment or question on air!Leave Karena a voicemail: https://www.speakpipe.com/KarenaDawnWhat happens when a cancer diagnosis collides with raising $10 million in venture capital?On this episode of The Big Silence, Karena sits down with Vanessa Rissetto, registered dietitian, CEO and co-founder of Culina Health, and cancer survivor who’s redefining resilience. From growing up in a Haitian household to building the only nutrition company backed by a big insurance provider, Vanessa’s story is proof that success is about more than grit — it’s about honesty, boundaries, and balance. She opens up about her diagnosis, how entrepreneurship pushed her to the brink, and why learning to say “no” has become her ultimate health strategy.How Do We Redefine Health and Success Beyond Hustle Culture?Vanessa shares how her cancer journey shifted her perspective from chasing external validation to prioritizing joy, mental health, and self-care, while still leading a groundbreaking health-tech company.(00:01:00) From Dietitian to Tech CEO: Building Culina HealthWhy Vanessa decided to take insurance when most dietitians catered only to the eliteHow COVID opened doors for telehealth and scaled her business to $1M in under a yearThe bold move that got Blue Cross Blue Shield on her cap table — a first in the industryHer mindset shift: every investor “no” was just practice for the next “yes”(00:10:30) Cancer, Entrepreneurship, and the Cost of External ValidationThe overlooked symptom that led to Vanessa’s breast cancer diagnosisRaising $10M in venture funding while undergoing treatment — and why she now calls it “f***ing stupid”How avoidance, anxiety, and resentment crept in post-diagnosisThe power of saying “no” as a complete sentence(00:17:00) Back to Basics: Nutrition, Myths, and Mental HealthWhy she believes restrictive diets like keto miss the bigger pictureThe truth about protein, fasting, and why micro-counting often backfiresHow Vanessa balances Doritos, home-cooked meals, and plant-based principlesNutrition as behavior change, not just “eat more vegetables”(00:29:00) Therapy, Caregiving, and Whole-Person HealingHow Culina Health integrates with physicians and therapists for 360° careThe role of dietitians in eating disorder recovery and mental health supportWhy therapy for caregivers is just as important as therapy for patientsVanessa’s own two-therapist system: one for trauma, one for feelings(00:35:00) Menopause, Midlife, and Finding JoyHer experience with medically induced menopause and brain fog Why women need different strategies after 35 How AI is reshaping the future of nutrition and health-techThe freedom of midlife: smaller circles, more joy, and living on your own termsThanks for the support from our partners, including: Guest ResourcesFollow Vanessa on InstagramLearn more about Culina HealthFollow Culina Health on InstagramIf this episode moved you, please consider supporting The Big Silence Foundation and exploring our resources:Connect with The

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Vanessa Rissetto: A CEO’s Honest Take on Nutrition, Mental Health, and Saying What You Mean is great

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