What Doctor's DON'T Tell You About Megadosing Creatine (Over 40) : 1447 episode artwork

EPISODE · Apr 12, 2026 · 30 MIN

What Doctor's DON'T Tell You About Megadosing Creatine (Over 40) : 1447

from The Human Upgrade: Biohacking for Longevity & Performance

My favorite creatine (discount code DAVETUBE): https://www.qualialife.com/ASPREYRECOMMENDSCreatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy, and total human performance. This episode reveals why creatine is a non-negotiable supplement for anyone serious about biohacking, longevity, and cognitive upgrades. Host Dave Asprey breaks down the myths and truths about creatine, uncovering how it enhances memory, supports your mitochondria, regulates mood, strengthens bones and heart function, and even aids fetal brain development during pregnancy. Drawing from decades of functional medicine, real-world biohacks, and new research featured in the Wall Street Journal, Dave explains how creatine works not only as a muscle booster but as a universal cellular fuel that supports brain benefits, memory improvement, and sleep optimization. Timestamps:0:00 – Introduction1:14 – Why Creatine Matters5:01 – History of Creatine6:09 – Debunking the Myths8:55 – 5 Ways Creatine Fuels Your Mind & Body16:25 – How to Maximize Absorption18:13 – Dosing: How Much & When to Take It19:07 – Forms of Creatine Explained19:50 – Special Use Cases21:28 – Biohacking Real-World Applications23:21 – What to Stack with Creatine24:50 – Choosing the Right Creatine28:40 – Recap & Key TakeawaysThank you to our sponsors! Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers.Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey’s BEYOND Conference: https://beyondconference.com/Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1:25 PMCreatine is not just a bodybuilding supplement anymore, and Host Dave Asprey breaks down the full science of why this cheap, safe, and massively underrated compound may be the single most versatile biohack available for boosting brain power, protecting mitochondria, building muscle, and extending longevity in both men and women.

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What Doctor's DON'T Tell You About Megadosing Creatine (Over 40) : 1447

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This episode is 30 minutes long.

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This episode was published on April 12, 2026.

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My favorite creatine (discount code DAVETUBE): https://www.qualialife.com/ASPREYRECOMMENDSCreatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy,...

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