EPISODE · Oct 7, 2025 · 26 MIN
What we now know about eggs, sperm, and fertility (new data, new ideas)
from Age Well with Dr Sophie Shotter
“While you can’t change the *number* of eggs you’re born with, you can change the *quality*” Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Co-host: https://fionamattesini.co.uk/ Listen to the episode to get the full low-down on everything discussed. Here are a few more notes: Polyunsaturated Fatty Acids (PUFAs) and Fish: Studies have also suggested that PUFAs may promote fertility by improving egg quality and implantation (Gaskins & Chavarro, 2018). Several large-cohort studies have shown that women who report higher intakes of omega-3 PUFAs have higher fecundability and reduced risk of anovulation (no ovulation). Women who reported a higher intake of trans fatty acids were found to have greater risk of infertility and reduced fecundability (Chavarro et al., 2007; Mumford et al., 2016; Wise et al., 2018). (Trans fatty acids are a type of fat found primarily in fried and other foods that are made with partially hydrogenated oils, and they are known to raise cholesterol levels.) Women who eat a lot of trans fatty acids have been found to have greater risk of fertility challenges (Chavarro et al., 2007; Mumford et al., 2016; Wise et al., 2018). Soy: See this comprehensive summary of the state of the research on phytoestrogens and soy by reproductive endocrinologist Amber Cooper, MD, at the Vios Fertility Institute in St. Louis, Missouri.) https://www.fertstert.org/article/S0015-0282(19)30621-1/fulltext Quitting Drinking and Smoking: Not only does drinking during pregnancy have significant risks for the fetus but drinking when trying to conceive can also pose problems. Alcohol has been shown to reduce female and male fertility, perhaps by impacting sperm quality (Fan et al., 2017; Karmon et al., 2017; La Vignera et al., 2013). If you’re having trouble conceiving, try reducing your alcohol intake. Smoking can cause reproductive issues and impaired fertility. Cigarette smoking is associated with reduced ovarian function and lower pregnancy rates in women (Vanvoorhis et al., 1996). Male smoking is associated with reduced semen quality, sperm development, sperm maturation, and sperm function (Dai et al., 2015). Recent studies have suggested that folic acid reduces the risk of miscarriage, while also conferring other benefits, such as better fertility and getting pregnant faster (Gaskins & Chavarro, 2018). In a study lactolycopene seemed to improve sperm motility and morphology in healthy men, increasing the proportion of fast sperm and normal morphology (Williams et all, 2020). Women who took FertilityBlend three times a day for three months had significantly more pregnancies (Lynn Marie Westphal et al., 2004). This positive finding was replicated in a subsequent larger controlled study (Westphal, Polan, & Trant, 2006). https://www.yourfertility.org.au/sites/default/files/2018-08/Howtoavoidchemicalsthatcanreduce_fertility.pdf https://www.su.se/english/research/human-eggs-prefer-some-men-s-sperm-over-others-research-shows-1.503532 https://edition.cnn.com/2020/06/09/health/sperm-choice-female-eggs-wellness https://www.healthline.com/health/substance-use/does-weed-affect-sperm#short-answer https://www.glamour.com/story/foods-that-increase-fertility Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast. Mentioned in this episode:This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers. Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off. This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot. Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.
What this episode covers
Why people struggle to conceive | new data on what helps | fertility supplements - is there such a thing? | egg quality | endocrine disruptors | the lifespan of sperm | fertility facts and myths
NOW PLAYING
What we now know about eggs, sperm, and fertility (new data, new ideas)
No transcript for this episode yet
Similar Episodes
Mar 26, 2026 ·1m
Mar 19, 2026 ·34m
Feb 18, 2026 ·11m
Feb 11, 2026 ·45m