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Jun 12, 2025 11 min

Why a Boy Could Not Feel Pain

from The Journal Club Hosted by Tom Jaramillo

CRISPR helps to show why a boy felt no pain. Nature. 2025 Jun; Antunes FTT, Gandini MA, Garcia-Caballero A, Huang S, Ali MY, Gambeta E, Souza IA, Harding EK, Ferron L, Stray-Pedersen A, Gadotti VM, Zamponi GW. A pathological missense mutation in the deubiquitinase USP5 leads to insensitivity to pain. J Exp Med. 2025 Aug 4

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Why a Boy Could Not Feel Pain

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