AI and Healthcare
by TensorBlack
AI and Healthcare by TensorBlack is a clinician-led conversation about what artificial intelligence is actually doing in cancer care — and what it will take to deploy it, and to trust it. Sanjay Juneja, MD, is a triple board-certified hematologist and medical oncologist and VP of Clinical AI at Tempus AI. Douglas Flora, MD, LSSBB, is executive medical director of oncology services at St. Elizabeth Healthcare and editor-in-chief of the journal AI in Precision Oncology. Guests are among the most credible voices in oncology and AI: Eric Lefkofsky, founder and CEO of Tempus AI; Anant Madabhushi, PhD, of Emory University; and Scott Penberthy of Google — alongside cancer center executives, health system leaders, health-policy attorneys, and the researchers publishing the underlying work. Conversations cover computational pathology and radiology, precision medicine and genomic sequencing, clinical decision support, digital twins, reimbur
Episodes
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How AI Reads Blood Cells to Help Diagnose Cancer with Gregory Goldgof, MD, PhD
In this episode of AI and Healthcare, oncologists Sanjay Juneja, MD and Doug Flora, MD sit down with Greg Goldgof, MD, PhD, MS, a computer scientist and board-certified pathologist, to talk about DeepHeme, the AI system his lab built to classify the cells in a bone marrow aspirate, the test at…
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What Changes When AI Can Read All of the EHR?
Every oncologist knows the electronic health record is where the cancer story goes to hide. Outside records arrive by fax, get scanned into the media tab under the wrong name, and pile up to hundreds of documents per patient from dozens of institutions, written in coding languages that never…
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The AI Doctor Debate: Autonomous AI in Healthcare with Zeke Emanuel, MD, PhD
Will AI replace doctors? Ezekiel "Zeke" Emanuel, MD, PhD, thinks autonomous AI will soon manage a lot of what physicians do today, starting with chronic disease and the side effects of chemotherapy, and that the better it gets, the more likely a human override is to add errors rather than catch...
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What AI Can See in Medical Scans That Doctors Can't
What if medical scans we already collect contain signals that could predict cancer treatment response, reveal disease risk years earlier, or identify biological patterns the human eye cannot see? In this episode of AI & Healthcare, oncologists Dr. Sanjay Juneja and Dr. Doug Flora, speak with AI…
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This Oncologist Started Learning AI at 60, Here's How He Uses It
Medicine is becoming too complex for any one clinician to keep up with alone. AI may soon change that equation. Dr. Francisco Esteva joins Dr. Sanjay Juneja and Dr. Doug Flora to explain how physicians can use AI to research faster, communicate more clearly with patients, automate repetitive…
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Can CMS turn Healthcare AI into a Billable Service
CMS just proposed rules that could decide who gets paid for AI in healthcare, and that's a bigger deal than another “better algorithm” story. Dr. Sanjay Juneja and Dr. Douglas Flora talk with Jordan Johnson (radiation oncology, healthcare finance, compliance and law) about what's actually in the...
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The End of Trial-and-Error Cancer Care
Eric Lefkofsky, Founder and CEO of Tempus AI, joins Dr. Sanjay Juneja and Dr. Doug Flora to explore how artificial intelligence, real-world data, genomic sequencing, and emerging technologies like organoids are reshaping oncology. From reducing diagnostic errors to matching patients with more...
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What If Every Patient Had a Digital Twin? Part 2
What happens when artificial intelligence becomes a trusted partner in patient care? Healthcare leaders are increasingly exploring how AI can help clinicians make faster, more informed decisions while reducing administrative burden and improving patient outcomes. But deploying AI in medicine...
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Can We Detect Cancer Before Symptoms Appear? Part 1
Cancer is often most treatable when it's found early—but what if we could detect it before symptoms ever appear? Advances in genomics, blood-based biomarkers, and artificial intelligence are giving researchers new ways to identify cancer earlier, understand disease at a deeper level, and move...
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Could Sleep Affect Cancer Survival?
Cancer treatment may be missing one of the body’s most important biological signals: circadian rhythm. In this conversation, sleep neurologist Dr. Anne Marie Morse explains how sleep timing, inflammation, immune function, and wearable data could fundamentally reshape cancer care. Emerging…
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AI Is Changing Healthcare — But At What Cost?
AI is transforming healthcare at an unprecedented pace—but the biggest risks aren’t clinical, they’re legal, operational, and systemic. From data center infrastructure and environmental impact to reimbursement shifts and agentic AI workflows, the stakes are rising fast. New models from major tech...
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What Clinical AI Is Doing Well... and Where It Still Needs Work
AI is making remarkable progress in healthcare — but translating that progress into real clinical impact is more complex than it seems. In this episode, we break down the State of Clinical AI in 2026, separating signal from noise and exploring what’s actually working today.
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Why Most AI Startups Fail in Healthcare
AI is exploding in healthcare — but most startups still fail. In this episode of the AI & Healthcare Podcast, Dr. Sanjay Juneja speaks with innovation leaders Dr. Bernardo Perez-Villa and Dr. Peter Alperin about the reality of building successful medical technology in 2026. Hundreds of AI tools...
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The Payment Crisis Behind Healthcare
Care is delivered every day in American hospitals, but getting paid for that care has become a battle. Denials, prior authorization, billing complexity, and rising costs have created a financial crisis behind the scenes of modern medicine. Insurance companies use automation to control payments,...
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How AI Creates Precision in Mental Health Care
Mental health is now central to high-quality cancer care, yet access, diagnostic precision, and scalability remain major gaps. In this in-depth discussion, clinical and innovation leaders explore how artificial intelligence can shift mental health care from reactive support to precision-driven,...
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Clinical AI Governance: What Clinicians Must Know in 2026
AI in healthcare is accelerating fast—but adoption without governance is risk. In this conversation, oncology and health policy leaders break down how clinicians and health systems should evaluate emerging AI tools: what FDA clearance vs approval really means, why “not FDA-approved” doesn’t...
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How Digital Twins Could End Medical Guesswork
Digital twins are moving from engineering into healthcare and the implications are profound. From oncology decision-making to clinical trials and personalized medicine, virtual human twins could reshape how clinicians predict outcomes, reduce toxicity, and tailor treatment. Dr. Sanjay Juneja and...
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How Wearables Are Transforming Oncology Care
Continuous monitoring is reshaping oncology. CEO of AION Biosystems, Sam Barend, joins Dr. Sanjay Juneja, Dr. Douglas Flora, and Dr. David Penberthy to explore how long‑term physiologic tracking, AI‑driven insights, and clinically validated wearables are improving outcomes for patients at high…
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The End of Cut, Poison & Burn: How AI is Rewriting Cancer Care
Cancer care isn't what it used to be—and that's exactly why Dr. Douglas Flora just wrote a book about it. Are you ready to understand how AI is transforming oncology? In this episode of AI and Healthcare, host Dr. Sanjay Juneja and co-hosts Dr. Douglas Flora and Dr. Deborah Pat are joined by...
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AI Is Changing Cancer Care and Policy
AI is changing everything from policy to the patient room. In this AI&H roundtable, Dr. Doug Flora, a leading voice in oncology innovation, joins Dr. Sanjay Juneja, Dr. Debra Patt, and Mika Newton to tackle what’s really holding back AI adoption in healthcare. They explore Medicare’s AI prior…
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Why AI Tools Are Changing Medicine Fast?
Healthcare is shifting fast, and AI is at the center of the storm. In this powerful roundtable, Dr. Sanjay Juneja hosts xCures CEO Mika Newton, Dr. Debra Patt of Texas Oncology, and Dr. Jason Hill of Ochsner Health to break down how AI is already reshaping access, risk, and care delivery. From...
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What Is Patient Design in Healthcare?
What is patient design, and why does it matter in modern healthcare? Dr. Bertalan Meskó, Director of The Medical Futurist Institute, explains why patient involvement is critical to innovation and trust. Patient-centered design shifts the model from making decisions for patients to making…
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Will Insurers Require AI for Value-Based Care?
Could AI soon become a required element of value-based care? Dr. Stephen Speicher from Flatiron Health explores a near-future scenario where insurers may require AI tools to be used in clinical workflows to qualify for reimbursement. In this forward-looking discussion, Dr. Speicher breaks down…
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Can You Refuse AI in Your Medical Care?
Should patients be able to opt out of AI in their care? Dr. Stephen Speicher, Head of Clinical Oncology and Safety at Flatiron Health, dives into the evolving ethics of informed consent as AI becomes increasingly embedded in medical workflows. From regulatory trends to future standards of care…
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How Vision Writing Changes Daily Decisions
What if your future self could guide your decisions today? Dr. Bertalan Mesko, Director of The Medical Futurist Institute, shares a surprisingly effective strategy: vision writing. By imagining yourself in the future and striking “deals” with future versions of yourself, you can create emotional...
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Why Predictive AI & Wearables Are Game-Changers
Predictive AI and wearable tech are changing healthcare from reactive to proactive. This clip explores how real-time data and AI models can detect illness before symptoms emerge. Jordan Johnson of Bridge Oncology and Dr. Sanjay Juneja discuss the future of medicine—from CMS reimbursements to…
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Bertalan Meskó on the Future of Healthcare
What will the future of healthcare really look like? Medical futurist Dr. Bertalan Meskó reveals how foresight, patient design, and prompt engineering are reshaping the landscape of care. In this interview with oncologist Dr. Sanjay Juneja, learn how to prepare for multiple futures, integrate AI...
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Responsible AI Needs Global Regulation
Should AI in health records be considered a medical device? Emily Lewis, an AI thought leader, compares the U.S. FDA and U.K. NHS approaches to AI regulation in healthcare. She shares how global discrepancies affect responsible AI implementation and what leaders must do to stay compliant.…
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Why Patient Care Suffers from Interoperability Issues
Interoperability isn’t just a buzzword—it’s a broken promise. Jordan Johnson, founder of Bridge Oncology, explains how fragmented systems, outdated data, and lack of standardization are driving financial loss and patient harm. From mismatched EMRs to payer confusion, this interview exposes the...
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Can AI Make Healthcare Safer and More Equitable?
How do we make healthcare AI both safe and scalable? Dr. Stephen Speicher, Head of Clinical Oncology and Safety at Flatiron Health, shares how responsibility for AI safety must be shared across developers, deployers, clinicians, and health systems. He breaks down use-case-specific risks, informed...
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The Reality of EHR API Adoption
Why are digital health companies still struggling to connect with EHRs—even after federal mandates? Dr. Ben Rosner breaks down results from a national survey exploring API integration challenges, from proprietary workarounds to endpoint confusion. He also previews a new survey aimed at measuring...
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Why Interoperability Fails in Healthcare
Healthcare data interoperability isn’t just about EMRs—it’s about patient survival, equity, and system sustainability. Jordan Johnson, MSHA, Founder of Bridge Oncology, breaks down the true scope of interoperability, from payer systems to AI-enabled radiotherapy. In this dynamic conversation with...
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Medical Education in 2025: AI’s Double-Edged Sword
Is AI helping—or harming—the next generation of doctors? UCSF's Dr. Ben Rosner shares how AI is reshaping medical education in 2025. From tutor bots to clinical skill assessments, he explores the opportunities and pitfalls. Discover what 'de-skilling' means, and why educators need smart…
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Can AI Write Better Discharge Summaries?
AI is transforming discharge documentation. Dr. Ben Rosner of UCSF breaks down how large language models (LLMs) perform compared to physicians—and what that means for safety, education, and clinical workflows. Learn what “LLM as jury” could mean for quality control and how AI might de-skill…
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Emily Lewis on AI and Patient Engagement
AI is no longer just for clinicians. Emily Lewis, an AI thought leader, explains how AI is becoming a partner in patient care. From gamified self-care tools to multimodal education, she breaks down how technology can foster better communication and empower patients to take control of their…
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Disruption vs. Sustaining Innovation in Healthcare
Disruptive innovation isn’t always what it seems—especially in healthcare. Bernardo Perez-Villa, Senior Innovations Engagement Partner at the Cleveland Clinic, shares a revealing look at the myths behind “first-in-class” innovation. Learn how startups create disruption, why big players wait to…
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The #1 Mistake Health Startups Make
Why do so many digital health startups collapse? Dr. Bernardo Perez-Villa explains how a lack of real market validation derails innovation before it starts. Learn how to perform meaningful primary and secondary market research—from asking the right questions to clinicians to scanning Reddit and...
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Why Most AI Startups in Healthcare Fail
What separates scalable healthcare AI from hype? Dr. Bernardo Perez-Villa, Cleveland Clinic's Senior Innovations Engagement Partner, breaks down how to validate AI ideas, assess product-market fit, and build business models that survive reimbursement hurdles. Hosted by Dr. Sanjay Juneja.
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Cancer Detection MRI Imaging vs Blood Tests
Why rely on one method when three are better? Ezra CEO Emi Gal explains how combining imaging, liquid biopsy, and biomarkers creates a superior cancer screening protocol. He also shares how AI enables longitudinal tracking of lesions, reducing false positives and patient anxiety. Learn what makes...
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How AI Makes Full-Body MRI Faster and Cheaper
Discover how Ezra uses FDA-cleared AI to transform MRI imaging. CEO Emi Gal explains how Ezra Flash speeds up scan times while improving quality, and how Ezra Assist aids radiologists with accurate annotations. Their AI-powered process makes full-body cancer screening possible in just 22...
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Should Patients Be Paid for Sharing Health Data?
Can patients and clinicians be fairly rewarded for sharing healthcare data? Rajeev Ronanki, CEO of Lyric, discusses a future where AI-enabled tools empower community oncology practices with personalized digital agents. He outlines how reimbursement models can support physicians scaling their care...
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AI Makes Full Body MRI Screening Affordable - with Emi Gal
Ezra CEO Emi Gal breaks down how AI is revolutionizing full-body MRI cancer screening. Learn how FDA-cleared tools accelerate scan time, assist radiologists, and empower patients with easy-to-understand reports—all for just $499. Discover why early detection matters, especially for younger…
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Inside the FDA’s Bold Elsa AI Move: Rajeev Ronanki Explains
Rajeev Ronanki, CEO of Lyric and former Elevance Health executive, unpacks what the FDA’s AI initiative—Elsa—really means for drug innovation and regulation. Rajeev outlines how the agency can use data it already has to drive smarter, faster decisions. He draws powerful parallels to autonomous...
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Trust, ethics, and data bias in AI
Trust in AI cannot exist without ethics - and ethics cannot exist without confronting data bias. Discover how artificial intelligence can become a force for safety, fairness, and innovation in healthcare when designed with integrity from the ground up. In this compelling exchange, Dr. Sanjay…
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Rajeev Ronanki: Real-Time Payer-Provider Collaboration
Rajeev Ronanki, CEO of Lyric and author of You and AI, joins Dr. Sanjay Juneja to discuss a radical rethinking of payment in healthcare. Instead of upgrading legacy systems, Rajeev proposes bypassing them using trusted AI agents that mediate between EMRs and payers. They explore real-time...
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Where does the AI liability lie?
AI in healthcare brings breakthroughs - but also new legal and ethical risks. Who’s responsible when an AI-assisted diagnosis leads to harm? The licensed physician? The hospital? The tool’s developer? As AI becomes embedded in clinical workflows, this question becomes unavoidable. In this...
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How does the Belmont Report relate to AI ethics in healthcare?
AI is reshaping clinical care, but can we apply trusted bioethical principles to its rapid adoption? This discussion explores how the Belmont Report’s three ethical pillars - autonomy, beneficence, and justice - remain essential as AI tools enter diagnosis, decision-making, and patient...
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Regulation vs Deregulation of AI in Healthcare
Is AI in healthcare racing toward a crash? Discover what happens when innovation outpaces oversight, and why unchecked growth could lead to another industry meltdown. Mika Newton, CEO of xCures (https://www.linkedin.com/in/mikanewton/), and Dr. Colleen Lyons, clinical research ethicist at…
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How is AI used in Life sciences?
AI transforms how healthcare data is structured, analyzed and applied to clinical decision-making in life sciences. Discover how leading experts harness artificial intelligence to streamline clinical workflows, enhance data quality and accelerate actionable insights for healthcare providers and...
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What are the risks of using AI in healthcare?
AI is changing healthcare - but are we prepared for the hidden risks? From undermining critical thinking to damaging the human connection between providers and patients, AI’s unintended consequences deserve attention. Mika Newton (CEO, xCures) talks with Dr. Spencer Dorn (Vice Chair, UNC…
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About this show
AI and Healthcare by TensorBlack is a clinician-led conversation about what artificial intelligence is actually doing in cancer care — and what it will take to deploy it, and to trust it.
Sanjay Juneja, MD, is a triple board-certified hematologist and medical oncologist and VP of Clinical AI at Tempus AI. Douglas Flora, MD, LSSBB, is executive medical director of oncology services at St. Elizabeth Healthcare and editor-in-chief of the journal AI in Precision Oncology.
Guests are among the most credible voices in oncology and AI: Eric Lefkofsky, founder and CEO of Tempus AI; Anant Madabhushi, PhD, of Emory University; and Scott Penberthy of Google — alongside cancer center executives, health system leaders, health-policy attorneys, and the researchers publishing the underlying work. Conversations cover computational pathology and radiology, precision medicine and genomic sequencing, clinical decision support, digital twins, reimbur
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