AUAUniversity

AUA2026: Focus on: Non-Muscle Invasive Bladder Cancer Update for the Urology Care Team CME Available: https://cme.auanet.org/URL/FOCUS263ONL LEARNING OBJECTIVES: After participating in this CME activity, participants will be able to: 1. Analyze emerging data in NMIBC and guideline updates to evaluate the impact of disease recurrence and treatment-related complications on current care pathways and patient outcomes. 2. Apply guideline-driven risk stratification in order to identify and select appropriate patients with high-risk NMIBC for optimal therapy sequencing and escalation of care. 3. Implement strategies for safe and effective integration of novel intravesical and systemic immunotherapies to strengthen multidisciplinary collaboration and shared decision-making between urology and medical oncology. 4. Develop patient-centered, evidence-informed care plans using guideline updates and real-world case examples, in order to address unmet needs, reduce recurrence risk, and improve quality of life for patients with NMIBC. ACKNOWLEDGEMENTS: Support provided by independent educational grants from: AstraZeneca ImmunityBio Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC UroGen Pharma, Inc.

Update Series (2026): Case Based Medical and Surgical Management of Peyronie's Disease Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Matthew Ziegelmann, MD Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit CME.auanet.org

AUA2026: Contemporary Management of Advanced Prostate Cancer: Guidelines and Beyond CME Available: https://cme.auanet.org/URL/26DC040ONL LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Identify appropriate use of genetic testing, genetic counseling as well as somatic testing. 2. Describe appropriate use of treatment-related to specific genetic alterations. 3. Identify appropriate combination therapy with ADT plus novel androgen receptor pathway inhibitors and chemotherapy. Early treatment intensification as well as appropriate de intensification will be discussed in mHSCPC. 4. Describe the treatments for non-metastatic CRPC and oncologic outcomes based on AUA/SUO and NCCN Guidelines. 5. Counsel patients on available treatment options for CRPC as well as combination therapy and sequencing based on AUA/SUO and NCCN Guidelines. ACKNOWLEDGEMENTS: Support provided by independent educational grants from: Astellas Lantheus Medical Imaging Novartis Pharmaceuticals Corporation Pfizer, Inc

AUA2026: Focus on: Muscle Invasive Bladder Cancer CME Available: https://cme.auanet.org/URL/FOCUS266ONL LEARNING OBJECTIVES: After participating in this CME activity, participants will be able to: 1. Evaluate limitations in the current MIBC treatment landscape including patient outcomes and gaps in available systemic therapies to identify individuals with limited or no effective treatment options and enhance clinical decision-making. 2. Interpret the mechanisms of action and clinical data supporting antibody-drug conjugates (ADCs) to determine their potential role in addressing unmet therapeutic needs in patients with MIBC who are ineligible for traditional treatment pathways. 3. Incorporate evidence-based perioperative systemic treatment strategies including neoadjuvant and adjuvant approaches into patient care algorithms to improve pathologic response rates and survival outcomes in MIBC. 4. Apply best practices for managing and mitigating adverse events associated with emerging systemic and perioperative therapies to optimize treatment adherence and patient safety in the MIBC setting. 5. Implement strategies for effective communication, multidisciplinary care coordination, and shared decision-making between urologists, medical oncologists, and patients to improve treatment alignment and patient-centered outcomes in MIBC. ACKNOWLEDGEMENTS: Support provided by an independent educational grant from: Pfizer, Inc.

AUA2026: Focus on: ADT in the Modern Era - Balancing Cancer Control and Cardiovascular Safety CME Available: https://cme.auanet.org/URL/FOCUS265ONL LEARNING OBJECTIVES: After participating in this CME activity, participants will be able to: 1. Integrate cardiovascular (CV) risk assessment into ADT initiation by applying key findings from the REVELUTION-1 trial to identify patients at elevated risk for atherosclerosis and MACE. 2. Compare and apply the CV safety profiles of LHRH agonists versus GnRH receptor antagonists to guide personalized ADT selection in patients with varying CV risk. 3. Implement streamlined monitoring strategies for men on oral ADT, including testosterone levels, lipid and blood pressure evaluation, and surveillance for early CV risk indicators. 4. Collaborate with cardiology and primary care to optimize statin use and coordinate CV risk-reduction strategies for prostate cancer patients receiving ADT. 5. Strengthen shared decision making and adherence by incorporating discussions of oncologic benefit, CV risk, and mitigation strategies into routine oral ADT counseling and follow-up. ACKNOWLEDGEMENTS: Support provided by independent educational grants from: Pfizer, Inc Sumitomo Pharma America, Inc.

Innovations in the Surgical Management of BPH (2026) CME Available: https://cme.auanet.org/URL/surgical-treatment-bph-2026 LEARNING OBJECTIVES: After participating in this educational series, participants will be able to: 1. Utilize the newly released AUA Guidelines Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia in practice. 2. Discuss the evidence base for current technologies, including pivotal studies, and be able to define the role and clinical expectation for each of them. 3. Interpret the current clinical results and compare the patient experiences of these treatments in relation to more established and even abandoned treatments for patient groups with similar characteristics. 4. Differentiate between each of the new technologies for treating BPH/LUTS based on both their mode-of-action and the quality of their supporting evidence. ACKNOWLEDGEMENTS: Support provided by independent educational grants from: - Olympus Corporation of the Americas - Teleflex Interventional Urology © 2026 AMERICAN UROLOGICAL ASSOCIATION. ALL RIGHTS RESERVED. ATTENTION: You are prohibited from using or uploading content you accessed through this activity into external applications, bots, software, or websites, including those using artificial intelligence technologies and infrastructure, including deep learning, machine learning and large language models and generative AI.

Update Series (2026) Lesson 18: Testosterone Therapy: Is It Safe? A Case-Based Approach Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit cme.auanet.org/URL/US2026

AUA Guidelines: Advanced Prostate Cancer Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Kristen R. Scarpato, MD, MPH To access the full guideline, please use the following link: https://www.auanet.org/guidelines-and-quality/guidelines/advanced-prostate-cancer

AUA2026: Focus on: Metastatic Urothelial Carcinoma CME Available: https://cme.auanet.org/URL/FOCUS264ONL LEARNING OBJECTIVES: After participating in this CME activity, participants will be able to: 1. Select appropriate first-line therapies for patients with locally advanced or metastatic urothelial carcinoma during initial treatment planning, in accordance with updated NCCN guidelines. 2. Evaluate holistic management approaches, including treatment sequencing, therapy transitions, and long-term follow-up for patients with locally advanced or metastatic urothelial carcinoma throughout the course of disease. 3. Implement strategies to recognize, monitor, and mitigate treatment-related adverse events in patients receiving systemic therapy for locally advanced or metastatic urothelial carcinoma. 4. Integrate shared decision-making tools and communication strategies into clinical practice to ensure alignment of treatment choices with patient values and caregiver input. 5. Distinguish between treatment pathways for different stages of advanced bladder cancer, including variant histologies to ensure accurate staging and appropriate therapy selection based on the latest NCCN guidelines. ACKNOWLEDGEMENTS Support provided by independent educational grants from: Merck & Co., Inc. Pfizer, Inc.

AUA Guidelines: Clinically Localized Prostate Cancer Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: James Eastham, MD, FACS To access the full guideline, please use the following link: https://www.auanet.org/guidelines-and-quality/guidelines/clinically-localized-prostate-cancer

Update Series (2026): Kidney Stones and the Infected Patient Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Mantu Gupta, MD Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit CME.auanet.org

AUA2026: Focus on: Biomarkers, MRI and PSMA PET Imaging in Prostate Cancer Webcast CME Available: https://cme.auanet.org/URL/FOCUS262ONL LEARNING OBJECTIVES: After participating in this CME activity, participants will be able to: 1. Critically appraise recent developments in imaging biomarkers and molecular diagnostics (e.g., genomic risk scores, liquid biopsy) and discuss how they complement MRI and PSMA PET in prostate cancer care. 2. Determine the optimal clinical scenarios (diagnostic, staging, recurrence, surveillance) in which PSMA PET/CT or PET/MRI adds value beyond conventional imaging. 3. Recognize potential pitfalls in PSMA PET interpretation — including false positives, false negatives, non–PSMA-expressing disease, and technical artifacts — and implement strategies to mitigate them. 4. Synthesize biomarker, MRI, and PSMA PET findings into a personalized management plan, including guiding biopsy, focal therapy, salvage therapy, or systemic treatments. 5. Select appropriate patients with radiorecurrent or organ-confined prostate cancer for advanced imaging and guide re-treatment decisions (e.g., salvage therapy, targeted radiotherapy). ACKNOWLEDGEMENTS: Support provided by independent educational grants from: Blue Earth Diagnostics, Inc. Lantheus Medical Imaging

AUA2026 Spotlight: PARP-Inhibitor Combination Treatments for the Urologic Care Team CME Available: https://cme.auanet.org/URL/PARP26ONL LEARNING OBJECTIVES: At the conclusion of this CME activity, participants will be able to: 1. Integrate biomarker and genetic testing principles into clinical workflows for patients with metastatic prostate cancer, including when to order testing, how to interpret HRR mutation results (inclusive of BRCA and non-BRCA), and how to address barriers to testing through multidisciplinary coordination. 2. Explain the mechanism of action of PARP inhibitors and the biological and clinical rationale for their use—both as monotherapy and in combination approaches—in the treatment of mPC. 3. Evaluate emerging efficacy and safety data on PARPi combinations, including patient subgroup analyses, sequencing strategies, and the role of combination therapy in different stages of mPC. 4. Apply best practices for side effect monitoring and mitigation in patients receiving PARP inhibitors alone or in combination, leveraging the multidisciplinary team for optimal therapy management and patient quality of life. 5. Implement guideline-concordant care strategies in practice, including genetic testing workflow implementation, coordination among care team members, and patient engagement in shared decision-making and clinical trial enrollment. 5. Utilize current evidence-based guidelines to select and sequence PARP inhibitor therapy for patients with mPC, optimizing oncologic outcomes while individualizing care based on molecular profile and patient-specific factors. ACKNOWLEDGEMENTS: Support provided by independent educational grants from: Astrazeneca Merck & Co., Inc Pfizer, Inc.

Update Series (2026) Lesson 15: Case-Based Testicular Cancer Clinical Practice Guidelines Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit cme.auanet.org/URL/US2026

AUA Guidelines: Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Jaspreet S. Sandhu, MD To access the full guideline, please use the following link: https://www.auanet.org/guidelines-and-quality/guidelines/bph-guideline. Please note that access to the full guideline requires user login. If you do not already have an account, you can create a free login.

AUA2026: Society of Women in Urology Meeting Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Amy N. Luckenbaugh, MD, FACS To register for AUA2026, please visit auanet.org/AUA2026/register!

AUA2026: Society of Urologic Oncology Meeting Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Dr. Kelvin A. Moses, MD, PhD & Dr. Mark A. Preston, MD, MPH To register for AUA2026, please visit auanet.org/AUA2026/register!

AUA2026: Society of Benign Prostate Disease Meeting Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Kevin Thomas McVary, MD, FACS To register for AUA2026, please visit auanet.org/AUA2026/register!

AUA Guidelines: Early Detection of Prostate Cancer Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Simpa Salami, MD, MPH Lin DW, Carlsson S, Filson CP, et al. Updates to Early Detection of Prostate Cancer: AUA/SUO Guideline (2026).J Urol. 0(0).10.1097/JU.0000000000004995. https://www.auajournals.org/doi/10.1097/JU.0000000000004995

AUA2026: Sexual Medicine Society of North America Meeting Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Landon Trost, MD, To register for AUA2026, please visit auanet.org/AUA2026/register!

AUA2026: Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) Meeting Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Anne Pelletier Cameron, MD, URPS To register for AUA2026, please visit auanet.org/AUA2026/register!

Update Series (2026): At-Home Diagnostic and Therapeutic Options in Men's Health Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Richard J. Fantus, MD Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit CME.auanet.org

AUA2026: Research Programming Preview: Amplifying the Impact of Research for Career Development Host: H. Henry Lai, MD Guest: Naveen Kachroo, MD, PhD Joining us today for this special episode brought to you by the AUA Office of Research, Research Education Committee, are Drs. H. Henry Lai and Naveen Kachroo discussing the dynamic research education programming planned at AUA2026. Head to auanet.org/AUA2026/register to check out the new and exciting programming at AUA2026 and to register!

Update Series (2026): Perioperative Management of Urinary Diversion: What Every Urologist Should Know Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Rohit Reddy, MD Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit CME.auanet.org

AUA2026: Advanced Cystoscopy Training for APPs Host: Mark L. Gonzalgo, MD, PhD, MBA Guests: Brett Johnson, MD and Davis Viprakasit, MD, FACS Tune in to hear straight from the experts about our newest Hands-On Skills Training offering - Advanced Cystoscopy Training for APPs, part of the pre-meeting programming at AUA2026! In this episode, Dr. Brett Johnson and Dr. Davis Viprakasit discuss all about what you can expect from the Advanced Cystoscopy Training for APPs, a new APP hands-on skills training being held at AUA2026. This training provides both a half-day of hands-on skills training in the most critical procedural areas of need for APPs, as well as a library of on-demand virtual didactics straight from the experts. Spaces are still available - for more information or to register, please visit https://www.auanet.org/AUA2026/program/pre-meeting-programs Outline: Segment #1: Why offer the Advanced Cystoscopy Training for APPs? Segment #2: Description of the course Segment #3: Unique aspects of the course Segment #4: Potential benefits to participants Segment #5: Future directions

LG-IR-NMIBC Treatment Landscape (Republished) Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Chad R. Ritch, MD, MBA, FACS CME Available: cme.auanet.org/URL/GUPOD251 ACKNOWLEDGEMENTS: Support provided by independent educational grants from: AstraZeneca Johnson & Johnson LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Differentiate between traditional and emerging intravesical therapies for LG-IR-NMIBC, considering mechanism of action, administration schedules, and patient eligibility to support individualized treatment planning. 2. Incorporate into practice shared decision-making strategies that align clinical recommendations with patient values, preferences, and quality-of-life considerations in the management of LG-IR-NMIBC. 3. Utilize practical approaches for integrating intravesical therapy into routine clinical workflows, including coordination among multidisciplinary teams, patient education, and follow-up to optimize adherence and outcomes.

NMIBC Treatment Landscape (Republished) Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Janet Kukreja, MD, MPH, FACS CME Available: https://cme.auanet.org/URL/GUPOD253 ACKNOWLEDGEMENTS: Support provided by independent educational grants from: AstraZeneca Johnson & Johnson LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Select and implement immunotherapy regimens for patients with NMIBC in accordance with current AUA Guideline recommendations, tailoring treatment choices to tumor characteristics and individual patient needs. 2. Incorporate FDA-approved gene therapy options into NMIBC management by aligning therapeutic approaches with patient-specific factors, disease risk profile, and evolving clinical evidence. 3. Develop and integrate practical strategies to anticipate, monitor, and manage treatment-related side effects and immune-related adverse events in NMIBC, ensuring patient safety and treatment continuity.

MIBC Treatment Landscape (Republished) Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Jen-Jane Liu, MD, FACS CME Available: https://cme.auanet.org/URL/GUPOD252 ACKNOWLEDGEMENTS: Support provided by independent educational grants from: AstraZeneca Johnson & Johnson LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Integrate immunotherapy and targeted therapy into the multimodal management of MIBC, selecting appropriate regimens and sequencing strategies based on current guidelines, clinical trial data, and patient-specific factors. 2. Evaluate the clinical role, mechanisms of action, and evidence base for targeted therapies in MIBC, including biomarker-driven selection to support personalized treatment planning. 3. Develop and apply practical approaches for preventing, monitoring, and managing immune-related adverse events and other toxicities associated with immunotherapy and targeted therapy to optimize patient safety, adherence, and quality of life.

AUA2025: Key Takeaways: Bladder Cancer Presenters: Patrick Hensley, MD & Janet Kukreja, MD

Update Series (2026) Lesson 5: Long-term Urinary Catheters: Their Role & Management of Complications Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit https://cme.auanet.org/URL/US2026

Adjuvant Therapy for Renal Cell Carcinoma Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Daniel Shapiro, MD, FACS CME Available: https://cme.auanet.org/URL/RCCPOD261 ACKNOWLEDGEMENTS: Support provided by an independent educational grant from: Merck & Co., Inc. LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Define adjuvant therapy, review current clinical guidelines, and recognize the current landscape of treatment options for patients with RCC. 2. Compare and contrast different adjuvant therapies available for RCC, including targeted therapies and immunotherapies. 3. Identify common side effects associated with adjuvant therapies for RCC and provide strategies for managing and mitigating these adverse events in clinical practice. 4. Discuss ongoing clinical trials and new therapeutic targets under investigation for adjuvant treatment of RCC.

Use of Suction Ureteroscopes for Kidney Stone Treatment: CVAC System Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Karen L. Stern, MD

Update Series: The Role of Nephrectomy in Advanced Kidney Cancer Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Sarah P. Psutka, M.D., M.S., F.A.C.S. Now in its 45th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit CME.auanet.org

AI for Prostate Cancer Treatment Planning  Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Wayne G. Brisbane, MD

AUA Guidelines: Salvage Therapy for Prostate Cancer Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Yaw Nyame, MD, MS, MBA Morgan TM, Boorjian SA, Buyyounouski MK, et al. Salvage therapy for prostate cancer: AUA/ASTRO/SUO guideline part I: introduction and treatment decision-making at the time of suspected biochemical recurrence after radical prostatectomy. J Urol. 2024;211(4):509-517. https://www.auajournals.org/doi/10.1097/JU.0000000000003892 Morgan TM, Boorjian SA, Buyyounouski MK, et al. Salvage therapy for prostate cancer: AUA/ASTRO/SUO guideline part II: treatment delivery for non-metastatic biochemical recurrence after primary radical prostatectomy. J Urol. 2024;211(4):518-525. https://www.auajournals.org/doi/10.1097/JU.0000000000003891 Morgan TM, Boorjian SA, Buyyounouski MK, et al. Salvage therapy for prostate cancer: AUA/ASTRO/SUO guideline part III: salvage therapy after radiotherapy or focal therapy, pelvic nodal recurrence and oligometastasis, and future directions. J Urol. 2024;211(4):526-532. https://www.auajournals.org/doi/10.1097/JU.0000000000003890

AUA Guidelines: Diagnosis and Management of Male Chronic Pelvic Pain Host: Mark L. Gonzalgo, MD, PhD, MBA Guests: Elise JB De, MD & Dane Johnson, MD Lai HH, Pontari MA, Argoff CE, et al. Male Chronic Pelvic Pain: AUA Guideline: Part I Evaluation and Management Approach. J Urol. 0(0). doi:10.1097/JU.0000000000004564. https://www.auajournals.org/doi/10.1097/JU.0000000000004564 Lai HH, Pontari MA, Argoff CE, et al. Male Chronic Pelvic Pain: AUA Guideline: Part II Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome. J Urol. 0(0). doi:10.1097/JU.0000000000004565. https://www.auajournals.org/doi/10.1097/JU.0000000000004565 Lai HH, Pontari MA, Argoff CE, at al. Male Chronic Pelvic Pain: AUA Guideline: Part III Treatment of Chronic Scrotal Content Pain. J Urol. 0(0). doi:10.1097/JU.0000000000004566. https://www.auajournals.org/doi/10.1097/JU.0000000000004566

NMIBC Treatment Landscape Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Janet Kukreja, MD, MPH, FACS CME Available: https://cme.auanet.org/URL/GUPOD253 ACKNOWLEDGEMENTS: Support provided by independent educational grants from: AstraZeneca Johnson & Johnson LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Select and implement immunotherapy regimens for patients with NMIBC in accordance with current AUA Guideline recommendations, tailoring treatment choices to tumor characteristics and individual patient needs. 2. Incorporate FDA-approved gene therapy options into NMIBC management by aligning therapeutic approaches with patient-specific factors, disease risk profile, and evolving clinical evidence. 3. Develop and integrate practical strategies to anticipate, monitor, and manage treatment-related side effects and immune-related adverse events in NMIBC, ensuring patient safety and treatment continuity.

MIBC Treatment Landscape Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Jen-Jane Liu, MD, FACS CME Available: auau.auanet.org/node/44077 ACKNOWLEDGEMENTS: Support provided by independent educational grants from: AstraZeneca Johnson & Johnson LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Integrate immunotherapy and targeted therapy into the multimodal management of MIBC, selecting appropriate regimens and sequencing strategies based on current guidelines, clinical trial data, and patient-specific factors. 2. Evaluate the clinical role, mechanisms of action, and evidence base for targeted therapies in MIBC, including biomarker-driven selection to support personalized treatment planning. 3. Develop and apply practical approaches for preventing, monitoring, and managing immune-related adverse events and other toxicities associated with immunotherapy and targeted therapy to optimize patient safety, adherence, and quality of life.

AUA Guidelines: Genitourinary Syndrome of Menopause  Host: Mark L. Gonzalgo, MD, PhD, MBA Guests: Tracey S. Wilson, MD & Una J. Lee, MD Genitourinary Syndrome of Menopause: AUA/SUFU/AUGS Guideline (2025) Kaufman MR, Ackerman LA, Amin KA, et al. The AUA/SUFU/AUGS Guideline on Genitourinary Syndrome of Menopause. J Urol. 0(0). doi:10.1097/JU.0000000000004589. https://www.auajournals.org/doi/10.1097/JU.0000000000004589

LG-IR-NMIBC Treatment Landscape Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: Chad R. Ritch, MD, MBA, FACS CME Available: https://cme.auanet.org/URL/GUPOD251 ACKNOWLEDGEMENTS: Support provided by independent educational grants from: AstraZeneca Johnson & Johnson LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Differentiate between traditional and emerging intravesical therapies for LG-IR-NMIBC, considering mechanism of action, administration schedules, and patient eligibility to support individualized treatment planning. 2. Incorporate into practice shared decision-making strategies that align clinical recommendations with patient values, preferences, and quality-of-life considerations in the management of LG-IR-NMIBC. 3. Utilize practical approaches for integrating intravesical therapy into routine clinical workflows, including coordination among multidisciplinary teams, patient education, and follow-up to optimize adherence and outcomes.

Core Curriculum: Surgical Management of Urolithiasis AUA Urology Core Curriculum: auau.auanet.org/core Host: Mark L. Gonzalgo, MD, PhD, MBA Guests: Marcelino E. Rivera, MD and T. Max Shelton, MD Outline: Segment 1: Acute Stone Event and Radiographic Evaluation Segment 2: Shock Wave Lithotripsy Segment 3: Ureteroscopy Segment 4: Percutaneous Nephrolithotomy Segment 5: Intracorporeal Lithotripsy Segment 6: Special Considerations

AUA2025: Key Takeaways: BPH Presenters: Bilal Chughtai, MD & Dean S. Elterman, MD, MSc, FRCSC

AUA2025: Key Takeaways: Lower Urinary Tract Reconstruction Presenters: George E. Koch, MD & Kurt A. McCammon, MD, FACS

AUA Guidelines: Recurrent Uncomplicated Urinary Tract Infections in Women Host: Mark L. Gonzalgo, MD, PhD, MBA Guests: A. Lenore Ackerman, MD, PhD & Melissa R. Kaufman, MD, PhD Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline (2025) Ackerman AL, Bradley M, D’Anci KE, Hickling D, Kim SK, Kirkby E. Updates to Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline (2025). J Urol. 0(0). doi: 10.1097/JU.0000000000004723

Anorectal Malformation AUA Urology Core Curriculum: auau.auanet.org/core Host: Mark L. Gonzalgo, MD, PhD, MBA Guests: Christina Ho, MD and Molly E. Fuchs, MD Outline: Segment 1: Anorectal Malformation Overview/Background Segment 2: Initial Evaluation and Management Segment 3: Cloacal Malformations Segment 4: Long-Term Bladder Management & Concern for CKD Segment 5: Other Considerations

AUA2025: Key Takeaways: Endourology/Stones Highlights Presenters: Davis Viprakasit, MD & Stephen Nakada MD, FACS, FRCS

Update Series (2025) Lesson 30: Beyond Ureteropelvic Junction: Case-Based Tips and Tricks in Robotic Ureteral Stricture Reconstructive Surgery Now in its 44th installment, the AUA Update Series is renowned for delivering high-quality lessons to practicing urologists, fellows and residents. All content is developed by internationally recognized experts in urology, making the AUA Update Series the most professional and sought-after self-study program available. Improve your practice and patient care by staying abreast of the latest treatments and surgical techniques in urology. For more information or to subscribe to the AUA Update Series, please visit AUAnet.org/Update25

The Latest Breakthroughs in LG-IR-NMIBC (2025) CME Available: auau.auanet.org/node/43689 After participating in this CME activity, participants will be able to: 1. Apply updated clinical evidence and treatment protocols for low-grade, intermediate-risk non-muscle invasive bladder cancer (NMIBC) in appropriate patient cases to reduce recurrence rates and improve clinical outcomes. 2. Improve clinical decision-making related to risk stratification and surveillance strategies for low-grade, intermediate-risk NMIBC based on pathophysiology, epidemiology, and progression patterns. 3. Support evidence-based, patient-centered treatment selection options for low-grade, intermediate-risk NMIBC by comparing traditional intravesical therapies with emerging treatments. 4. Interpret the efficacy and safety profiles of new therapies to appropriately integrate new therapeutic options into clinical practice (upon regulatory approval). 5. Utilize new medications in the evolving treatment landscape following an evaluation of key clinical trial data from recent studies. 6. Assess the impact of treatment options on patient-reported outcomes, including quality of life and treatment burden, to guide shared decision-making and optimize care delivery. ACKNOWLEDGEMENTS Support provided by an independent educational grant from: UroGen Pharma, Inc.

The Latest Breakthroughs in mHSPC CME Available: https://auau.auanet.org/node/43825 After participating in this CME activity, participants will be able to: 1.Evaluate the concept of personalized therapy and its importance in the treatment of de novo mHSPC. 2.Implement current clinical guidelines for biomarker testing in mHSPC. 3.Explain the role of the PI3K/AKT pathway in prostate cancer biology. 4.Explore collaborations between urologists, oncologists, radiologists, and other healthcare professionals in managing de novo mHSPC. 5.Employ strategies to manage and mitigate common adverse events associated with AKT inhibitors and other therapies used in mHSPC. Acknowledgements: AstraZeneca Bayer HealthCare Pharmaceuticals Inc.

AUA2025: Key Takeaways: Sexual Dysfunction Highlights Presenter: Brittany Berk, MD & Arthur Burnett, MD, MBA