CardioPractice Cardio Talk

With Thomas Luscher, Royal Brompton and Harefield NHS Foundation Trust, London - UK and Marc Ferrini, CH Saint Joseph and Saint Luc, Lyon - France. In this podcast, Thomas Luscher joins Marc Ferrini to discuss if we can still drink coffee.   References :  European Prospective Investigation into Cancer and Nutrition (EPIC).  https://epic.iarc.fr/ National Health and Nutrition Examination Survey (NHANES} https://www.cdc.gov/nchs/nhanes/index.html Luscher TF. Start your day with a morning coffee! Eur Heart J. 2025 Feb 21;46(8):760-762. https://academic.oup.com/eurheartj/article/46/8/760/7928645 Wang X, Ma H, Sun Q, Li J, Heianza Y, Van Dam RM, Hu FB, Rimm E, Manson JE, Qi L. Coffee drinking timing and mortality in US adults. Eur Heart J. 2025 Feb 21;46(8):749-759. https://doi.org/10.1093/eurheartj/ehae871https://academic.oup.com/eurheartj/article/46/8/749/7928425 Corti R, Binggeli C, Sudano I, Spieker L, Hanseler E, Ruschitzka F, Chaplin WF, Lüscher TF, Noll G. Coffee acutely increases sympathetic nerve activity and blood pressure independently of caffeine content: role of habitual versus nonhabitual drinking. Circulation. 2002 Dec 3;106(23):2935-40. https://www.ahajournals.org/doi/10.1161/01.cir.0000046228.97025.3a

With Dimitri Richter, Euroclinic of Athens, Athens - Greece and Ricardo Asteggiano, Laboratorio Analisi Ricerca Clinica, Turin - Italy. In this podcast, Dimitri Richter joins Ricardo Asteggiano to discuss if e-cigarettes are safe.   REFERENCES:  Kang D, Choi KH, Kim H, Park H, Heo J, Park TK, Lee JM, Cho J, Yang JH, Hahn JY, Choi SH, Gwon HC, Song YB. Prognosis after switching to electronic cigarettes following percutaneous coronary intervention: a Korean nationwide study. Eur Heart J. 2025;46:84-95. https://academic.oup.com/eurheartj/article/46/1/84/7828721 Münzel T, Crea F, Rajagopalan S, Lüscher T. Nicotine and the cardiovascular system: unmasking a global public health threat. Eur Heart J. 2025 Dec 18:ehaf1010. https://academic.oup.com/eurheartj/advancearticle/doi/10.1093/eurheartj/ehaf1010/8377624  

With Mirvat Alasnag, King Fahd Armed Forces Hospital, Jeddah - Saudi Arabia and Thomas Kümler, Steno Diabetes Center, Copenhagen, Herlev - Denmark In this podcast, Mirvat Alasnag joins Thomas Kumler to discuss TAVI in women.   References:   1. Tchetche D, Pibarot P, Bax JJ, Bonaros N, Windecker S, Dumonteil N, Nietlispach F, Messika-Zeitoun D, Pocock SJ, Berthoumieu P, Swaans MJ, Timmers L, Rudolph TK, Bleiziffer S, Leroux L, Modine T, van der Kley F, Auffret V, Tomasi J, Stastny L, Hengstenberg C, Andreas M, Leclercq F, Gandet T, Mascherbauer J, Trescher K, Prendergast B, Vasa-Nicotera M, Chieffo A, Mares J, Wesselink W, Rakova R, Kurucova J, Bramlage P, Eltchaninoff H. Transcatheter vs. surgical aortic valve replacement in women: the RHEIA trial. Eur Heart J. 2025;46:2079–88. doi:10.1093/eurheartj/ehaf133. https://academic.oup.com/eurheartj/article/46/22/2079/8103699   2. Eltchaninoff H, Bonaros N, Prendergast B, Nietlispach F, Vasa-Nicotera M, Chieffo A, Pibarot P, Bramlage P, Sykorova L, Kurucova J, Bax JJ, Windecker S, Dumonteil N, Tchetche D. Rationale and design of a prospective, randomized, controlled, multicenter study to evaluate the safety and efficacy of transcatheter heart valve replacement in female patients with severe symptomatic aortic stenosis requiring aortic valve intervention (Randomized researcH in womEn all comers wIth Aortic stenosis [RHEIA] trial). Am Heart J. 2020;228:27–35. https://www.sciencedirect.com/science/article/pii/S0002870320301964   3. Silva I, Alperi A, Hecht S, Zanuttini A, Théron A, Giuliani C, Camacho B, Dahou A, Mares J, Bax J, Bonaros N, Windecker S, Messika-Zeitoun D, Wesselink W, Rakova R, Bramlage P, Tchétché D, Eltchaninoff H, Pibarot P; RHEIA Trial Investigators. Echocardiographic results of transcatheter versus surgical aortic valve replacement in women with severe aortic stenosis: the RHEIA trial. J Am Heart Assoc. 2025. doi:10.1161/JAHA.125.047196. https://www.ahajournals.org/doi/10.1161/JAHA.125.047196   4. Eltchaninoff H, Windecker S, Mack MJ, Pibarot P, Thourani VH, Bax JJ, Cohen DJ, Bonaros N, Makkar R, Bleiziffer S, Szeto WY, Berthoumieu P, Hahn RT, Hovorka T, Mareš J, Taylor J, Tchetche D, Leon MB. Aortic Valve Replacement in Women: A Pooled Analysis of the RHEIA and PARTNER 3 Trials. JACC Cardiovasc Interv. 2025;18:1540-53. https://www.jacc.org/doi/10.1016/j.jcin.2025.03.036   5. Herrmann HC, Mehran R, Blackman DJ, Bailey S, Möllmann H, Abdel-Wahab M, Ben Ali W, Mahoney PD, Ruge H, Wood DA, Bleiziffer S, Ramlawi B, Gada H, Petronio AS, Resor CD, Merhi W, Garcia Del Blanco B, Attizzani GF, Batchelor WB, Gillam LD, Guerrero M, Rogers T, Rovin JD, Szerlip M, Whisenant B, Deeb GM, Grubb KJ, Padang R, Fan MT, Althouse AD, Tchétché D; SMART Trial Investigators. Self-expanding or balloon-expandable TAVR in patients with a small aortic annulus (SMART trial). N Engl J Med. 2024;390:1959–71. https://www.nejm.org/doi/10.1056/NEJMoa2312573   6. Herrmann HC, Tchetche D, Mehran R, et al. SMART trial 2-year outcomes: continued superior valve performance for the self-expanding TAVR system in small annulus patients. Presented at CRT 2025: 8-11 March 2025, Washington, DC, USA   7. Praz F, Borger MA, Lanz J, Marin-Cuartas M, Abreu A, Adamo M, Ajmone Marsan N, Barili F, Bonaros N, Cosyns B, De Paulis R, Gamra H, Jahangiri M, Jeppsson A, Klautz RJM, Mores B, Pérez-David E, Pöss J, Prendergast BD, Rocca B, Rossello X, Suzuki M, Thiele H, Tribouilloy CM, Wojakowski W; ESC/EACTS Scientific Document Group. 2025 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J. 2025;46:4635–736. https://academic.oup.com/eurheartj/article/46/44/4635/8234488   8. Mack MJ, Leon MB, Thourani VH, Makkar R, Kodali SK, Russo M, Kapadia SR, Malaisrie SC, Cohen DJ, Pibarot P, Leipsic J, Hahn RT, Blanke P, Williams MR, McCabe JM, Brown DL, Babaliaros V, Goldman S, Szeto WY, Genereux P, Pershad A, Pocock SJ, Alu MC, Webb JG, Smith CR; PARTNER 3 Investigators. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients (PARTNER 3). N Engl J Med. 2019;380:1695–705. https://www.nejm.org/doi/10.1056/NEJMoa1814052   9. Kodali S, Williams MR, Doshi D, Hahn RT, Humphries KH, Nkomo VT, Cohen DJ, Douglas PS, Mack M, Xu K, Svensson L, Thourani VH, Tuzcu EM, Weissman NJ, Leon M, Kirtane AJ. Sex-specific differences at presentation and outcomes among patients undergoing transcatheter aortic valve replacement: a cohort study. Ann Intern Med. 2016;164:377–84. https://www.acpjournals.org/doi/10.7326/M15-0121   10. Chieffo A, Petronio AS, Mehilli J, Chandrasekhar J, Sartori S, Lefèvre T, Presbitero P, Capranzano P, Tchetche D, Iadanza A, Sardella G, Van Mieghem NM, Meliga E, Dumonteil N, Fraccaro C, Trabattoni D, Mikhail G, Sharma S, Ferrer MC, Naber C, Kievit P, Baber U, Snyder C, Sharma M, Morice MC, Mehran R; WIN-TAVI Investigators. 1-Year Clinical Outcomes in Women After Transcatheter Aortic Valve Replacement: Results From the First WIN-TAVI Registry. JACC Cardiovasc Interv. 2018;11:1–12. https://www.jacc.org/doi/10.1016/j.jcin.2017.09.034   11. Tateishi K, Hmoud H, De Gregorio I, Hastings R, De Gregorio J. The impact of gender on outcomes of transcatheter aortic valve implantation between self-expanding valve and balloon-expandable valve. Cardiovasc Revasc Med. 2024;63:38–42. https://www.sciencedirect.com/science/article/abs/pii/S1553838924000034   12. Iribarren AC, AlBadri A, Wei J, Nelson MD, Li D, Makkar R, Merz CNB. Sex differences in aortic stenosis: identification of knowledge gaps for sex-specific personalized medicine. Am Heart J Plus. 2022;21:100197. https://pmc.ncbi.nlm.nih.gov/articles/PMC9629620/   13. Springhetti P, Abdoun K, Clavel M-A. Sex differences in aortic stenosis: from the pathophysiology to the intervention, current challenges, and future perspectives. J Clin Med. 2024;13:4237. https://www.mdpi.com/2077-0383/13/14/4237   14. Tastet L, Kwiecinski J, Pibarot P, Capoulade R, Everett RJ, Newby DE, Shen M, Guzzetti E, Arsenault M, Bédard É, Larose É, Beaudoin J, Dweck M, Clavel MA. Sex-related differences in the extent of myocardial fibrosis in patients with aortic valve stenosis. JACC Cardiovasc Imaging. 2020;13:699–711. https://www.jacc.org/doi/10.1016/j.jcmg.2019.06.014   15. Treibel TA, Kozor R, Schofield R, Benedetti G, Fontana M, Bhuva AN, Sheikh A, López B, González A, Manisty C, Lloyd G, Kellman P, Díez J, Moon JC. Reverse myocardial remodeling following valve replacement in patients with aortic stenosis. J Am Coll Cardiol. 2018;71:860–71. https://www.jacc.org/doi/10.1016/j.jacc.2017.12.035   16. Stangl V, Baldenhofer G, Laule M, Baumann G, Stangl K. Influence of sex on outcome following transcatheter aortic valve implantation (TAVI): systematic review and meta-analysis. J Interv Cardiol. 2014;27:531–9. https://onlinelibrary.wiley.com/doi/epdf/10.1111/joic.12150   17. Tribouilloy C, Bohbot Y, Rusinaru D, Belkhir K, Diouf M, Altes A, Delpierre Q, Serbout S, Kubala M, Levy F, Maréchaux S, Enriquez Sarano M. Excess mortality and undertreatment of women with severe aortic stenosis. J Am Heart Assoc. 2021;10:e018816.   18. Bienjonetti-Boudreau D, Fleury M-A, Voisine M, Paquin A, Chouinard I, Tailleur M, et al. Impact of sex on the management and outcome of aortic stenosis patients. Eur Heart J. 2021;42(27):2683–2691. https://www.ahajournals.org/doi/10.1161/JAHA.120.018816

With Tiziana Claudia Aranzulla, Mauriziano Umberto Hospital, Turin - Italy and Ricardo Asteggiano, Laboratorio Analisi Ricerca Clinica, Turin - Italy. In this podcast, Tiziana Aranzulla joins Ricardo Asteggiano to discuss the management of women's heart health.   REFERENCES: Greenwood BN, Carnahan S, Huang L. Patient-physician gender concordance and increased mortality among female heart attack patients. Proc Natl Acad Sci USA. 2018 Aug 21;115(34):8569-74. https://www.pnas.org/doi/10.1073/pnas.1800097115 CardioDonna Project: https://www.youtube.com/watch?v=V4dauT9OMUc   https://www.insalutenews.it/in-salute/medicina-di-genere-salvata-la-prima-paziente-al-centro-cardiodonna-del-mauriziano-di-torino  Noelle Russell: https://www.youtube.com/watch?v=4ZRdje_TZFo

With Eva Gerdts, University of Bergen, Bergen - Norway and Marc Ferrini, CH Saint Joseph and Saint Luc, Lyon - France.   In this podcast, Eva Gerdts joins Marc Ferrini to discuss menopause and cardiovascular risk.   REFERENCES: Swan study:  El Khoudary SR, Greendale G, Crawford SL, Avis NE, Brooks MM, Thurston RC, Karvonen-Gutierrez C, Waetjen LE, Matthews K. The menopause transition and women's health at midlife: a progress report from the Study of Women's Health Across the Nation (SWAN). Menopause. 2019;26:1213-27.  Joint analysis of four population cohorts in the USA: Ji H, Kim A, Ebinger JE, Niiranen TJ, Claggett BL, Bairey Merz CN, Cheng S. Sex Differences in Blood Pressure Trajectories Over the Life Course. JAMA Cardiol. 2020 Mar 1;5:19-26. Erratum in: JAMA Cardiol. 2020 Mar 1;5(3):364.  Women's Health Initiative HERS study: Grady D, Applegate W, Bush T, Furberg C, Riggs B, Hulley SB. Heart and Estrogen/progestin Replacement Study (HERS): design, methods, and baseline characteristics. Control Clin Trials. 1998 Aug;19(4):314-35. 

With William John McKenna, University College London, London -  UK and Marc Ferrini, CH Saint Joseph and Saint Luc, Lyon - France.   In this podcast, William John McKenna joins Marc Ferrini to discuss how to implement a diagnosis of hypertrophic cardiomyopathy in 2026.

With Alex Horby Christensen, Copenhagen University Hospital - Rigshospitalet, Copenhagen - Denmark and Thomas Kumler, Herlev-Gentofte Hospital and Steno Diabetes Center, Herlev - Denmark. In this podcast, Alex Horby Christensen joins Thomas Kumler to discuss the challenges of the treatment of hypertrophic cardiomyopathy in 2026.

With Konstantinos Toutouzas, National & Kapodistrian University of Athens - Greece and Stefano Nistri, CMSR Veneto Medica, Altavilla Vicentina - Italy. In this podcast, Konstantinos Toutouzas joins Stefano Nistri to discuss the assessment of asymptomatic patients with aortic valve stenosis.

With Victoria Delgado, Germans Trias i Pujol Hospital, Barcelona - Spain and Stefano Nistri, CMSR Veneto Medica, Altavilla Vicentina - Italy.   In this podcast, Victoria Delgado joins Stefano Nistri to discuss the management of heart failure in patients with aortic stenosis.

With Cecilia Linde, President-Elect of the ESC, Karolinska Institute, Stockholm - Sweden and Marc Ferrini, Editor-in-Chief CardioPractice, CH Saint Joseph and Saint Luc, Lyon - France. In this podcast, Cecilia Linde joins Marc Ferrini to discuss general cardiology and cardiometabolic diseases. 

With Marta Farrero, Task Force Coordinator of the "2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease", Heart Failure and Transplant Unit, Hospital Clinic of Barcelona, Barcelona - Spain and Ruxandra Christodorescu, CardioPractice Board member, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania. In this podcast, Marta Farrero joins Ruxandra Christodorescu to discuss heart failure and mental health. Reference: Bueno H, Deaton C, Farrero M, Forsyth F, Braunschweig F, Buccheri S, Dragan S, Gevaert S, Held C, Kurpas D, Ladwig KH, Lionis CD, Maas AHEM, Merșa CO, Mindham R, Pedersen SS, Rojnic Kuzman M, Szmit S, Taylor RS, Uchmanowicz I, Vilchinsky N; ESC Scientific Document Group. 2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease: developed under the auspices of the ESC Clinical Practice Guidelines Committee. Eur Heart J. 2025 Nov 3;46(41):4156-4225. doi: 10.1093/eurheartj/ehaf191.

With Hector Bueno, Task Force Co-Chairperson of the "2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease", National Centre for Cardiovascular Research (CNIC), Madrid - Spain and Ruxandra Christodorescu, CardioPractice Board member, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania. In this podcast, Hector Bueno joins Ruxandra Christodorescu to discuss sex and gender differences in mental health.   Reference: Bueno H, Deaton C, Farrero M, Forsyth F, Braunschweig F, Buccheri S, Dragan S, Gevaert S, Held C, Kurpas D, Ladwig KH, Lionis CD, Maas AHEM, Merșa CO, Mindham R, Pedersen SS, Rojnic Kuzman M, Szmit S, Taylor RS, Uchmanowicz I, Vilchinsky N; ESC Scientific Document Group. 2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease: developed under the auspices of the ESC Clinical Practice Guidelines Committee. Eur Heart J. 2025 Nov 3;46(41):4156-4225. doi: 10.1093/eurheartj/ehaf191. 

With Konstantinos Koskinas, Chair of new ESC Lipid Guidelines, Bern University Hospital, Inselspital, Bern - Switzerland and Dimitrios Richter, Editorial Board CardioPractice, Euroclinic of Athens, Athens - Greece.  In this podcast, Konstantinos Koskinas joins Dimitrios Richter to discuss the updated 2025 ESC Lipid Guidelines - novelties of the new Guidelines.   REFERENCE: Mach F, et al. 2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias. Eur Heart J 2025 Aug 29:ehaf190.

With Neil Stone, Feinberg School of Medicine, Northwestern University, Evanston, IL, and Vascular Center of Bluhm Cardiovascular Institute Northwestern Memorial Hospital, Chicago, IL, USA, and Luigina Guasti, ESC Chair of the ESC Council of CardioPractice, University of Insubria, Varese - Italy. Volume dedicated to Scott Grundy, a pioneer in lipidology.   In this podcast, Neil J. Stone joins Luigina Guasti to pay tribute to Scott Grundy, a pioneer in lipidology.   REFERENCE:   Stone, NJ, et al. In memoriam: A tribute to Scott M. Grundy. J Clin Lipidol. 2025;19(1)1:3-6.

With Isabella Sudano, Department of cardiology, University Hospital Zurich (USZ), Zurich - Switzerland and Ruxandra Christodorescu, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania. In this podcast, Isabella Sudano joins Ruxandra Christodorescu to discuss working towards patient-centred care in hypertension.

With Rosa Maria Bruno, INSERM U970 Team 3, Paris Cardiovascular Research Centre – PARCC & Pharmacology & Hypertension Unit, Hôpital Européen Georges, Pompidou – APHP, Paris - France, and Marc Ferrini, CH Saint Joseph and Saint Luc, Lyon - France. In this podcast, Rosa Maria Bruno joins Marc Ferrini to discuss when and how to screen for secondary hypertension.

With Carlos Aguiar, Hospital Santa Cruz, Lisbon - Portugal, Luigina Guasti, University of Insubria, Varese - Italy, and Riccardo Asteggiano, LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy. In this podcast, Carlos Aguiar joins Luigina Guasti and Riccardo Asteggiano to discuss the visions of general cardiology today and tomorrow.

With Simone Moglio, Department of Surgical Sciences, University of Turin, Turin - Italy, Riccardo Asteggiano, LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy.   In this podcast, Simone Moglio joins Riccardo Asteggiano to discuss sleep apnoea in people with ortolayrngeal problems.

With Morten Kjobek Lamberts, Department of Cardiology, Herlev-Gentofte Hospital, University of Copenhagen, Institute for Clinical Medicine, Copenhagen - Denmark and Thomas Kumler, Steno Diabetes Center Copenhagen, Herlev - Denmark.    In this podcast, Morten Lamberts joins Thomas Kumler to discuss what cardiologists should know about sleep apnoea.

With Emil Wolsk, Herlev-Gentofte Hospital, Herlev - Denmark and Thomas Kümler, Herlev-Gentofte Hospital and Steno Diabetes Center Copenhagen, Herlev and University of Copenhagen, Institute for Clinical Medicine, Copenhagen - Denmark. In this podcast, Emil Wolsk joins Thomas Kümler to discuss dyspnoea of unknown cause.

With Wolfram Doehner, Berlin Institute of Health Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Deutsches Herzzentrum der Charité (DHZC), Campus Virchow Klinikum, Charité -  Universitätsmedizin Berlin, German Centre for Cardiovascular Research, Partner Site Berlin, and Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin - Germany, and Thomas Kümler, Herlev-Gentofte Hospital and Steno Diabetes Center Copenhagen, Herlev, and University of Copenhagen, Institute for Clinical Medicine, Copenhagen - Denmark.   In this podcast, Wolfram Doehner joins Professor Thomas Kümler to discuss stroke prevention in heart failure.   Reference: Doehner W, Böhm M, Boriani G, Christersson C, Coats AJS, Haeusler KG, Jones ID, Lip GYH, Metra M, Ntaios G, Savarese G, Shantsila E, Vilahur G, Rosano G. Interaction of heart failure and stroke: A clinical consensus statement of the ESC Council on Stroke, the Heart Failure Association (HFA) and the ESC Working Group on Thrombosis. Eur J Heart Fail. 2023 Dec;25(12):2107-29. https://onlinelibrary.wiley.com/doi/10.1002/ejhf.3071

With Mario Bocchiardo, Santa Corona Hospital, Pietra Ligure (SV) - Italy and Riccardo Asteggiano, LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy. In this podcast, Mario Bocchiardo joins Ricardo Asteggiano to discuss atrial fibrillation screening in patients with cryptogenic stroke.

With Davide Forno, Maria Vittoria Hospital Turin - Italy and Riccardo Asteggiano, LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy. In this podcast, Davide Forno joins Riccardo Asteggiano to discuss patent foramen ovale.

With Roberto Pedretti, University of Milan Bicocca, Milan - Italy, and Luigina Guasti, University of Insubria, Varese - Italy and Chair of the ESC Council of CardioPractice. In this podcast, Roberto Pedretti joins Luigina Guasti to discuss cardiovascular risk factors in older adults.

With Thomas Kümler, Complications Research, Steno Diabetes Center Copenhagen, Herlev, Herlev-Gentofte University Hospital and University of Copenhagen, Institute for Clinical Medicine, Copenhagen - Denmark and Professor Marco Proietti, Department of Internal and Geriatric Medicine, University of Milan, Milan - Italy. In this podcast, Marco Proietti joins Thomas Kümler to discuss stroke in older adults.

With Miguel Camafort-Babkowki, Hospital Clinic of Barcelona - Spain, and Ruxandra Christodorescu, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania. Miguel Camafort-Babkowski joins Ruxandra Christodorescu to discuss hypertension and heart failure.

With Rosa Maria Bruno, Paris Cardiovascular Research Centre – PARCC, Pharmacology & Hypertension Unit, European Hospital Georges Pompidou APHP, Paris, and Marc Ferrini, CH Saint Joseph and Saint Luc, Lyon - France. In this podcast, Rosa Maria Bruno joins Marc Ferrini to discuss hypertension in pregnancy. Reference: McEvoy JW, McCarthy CP, Bruno RM, Brouwers S, Canavan MD, Ceconi C, Christodorescu RM, Daskalopoulou SS, Ferro CJ, Gerdts E, Hanssen H, Harris J, Lauder L, McManus RJ, Molloy GJ, Rahimi K, Regitz-Zagrosek V, Rossi GP, Sandset EC, Scheenaerts B, Staessen JA, Uchmanowicz I, Volterrani M, Touyz RM; ESC Scientific Document Group. 2024 ESC Guidelines for the management of elevated blood pressure and hypertension.  Eur Heart J. 2024;45:3912-4018

With Alexander Kharlamov, De Haar Research Task Force, Rotterdam - The Netherlands, and Pepijn Adriaan Van Diemen, Amsterdam University Medical Centre, Amsterdam - The Netherlands. In this podcast, Alexander Kharlamov joins Pepijn Adriaan Van Diemen to discuss how to choose whether to be or not to be invasive in patients with chronic coronary syndrome. REFERENCE Vrints C, Andreotti F, Koskinas KC, Rossello X, Adamo M, Ainslie J, Banning AP, Budaj A, Buechel RR, Chiariello GA, Chieffo A, Christodorescu RM, Deaton C, Doenst T, Jones HW, Kunadian V, Mehilli J, Milojevic M, Piek JJ, Pugliese F, Rubboli A, Semb AG, Senior R, Ten Berg JM, Van Belle E, Van Craenenbroeck EM, Vidal-Perez R, Winther S; ESC Scientific Document Group. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J. 2024 Sep 29;45(36):3415-3537. https://academic.oup.com/eurheartj/article/45/36/3415/7743115 DISCLOSURES: Alexander Kharlamov and Pepijn Adriaan Van Diemen have no conflicts of interest to declare.

With Alexander Kharlamov, De Haar Research Task Force, Rotterdam, The Netherlands, and Pepijn Adriaan Van Diemen, Amsterdam University Medical Centre, Amsterdam, The Netherlands In this podcast, Alexander Kharlamov joins Pepijn Adriaan Van Diemen to discuss how to choose between anatomic vs functional tests in chronic coronary syndrome patients. Reference: Vrints C, Andreotti F, Koskinas KC, Rossello X, Adamo M, Ainslie J, Banning AP, Budaj A, Buechel RR, Chiariello GA, Chieffo A, Christodorescu RM, Deaton C, Doenst T, Jones HW, Kunadian V, Mehilli J, Milojevic M, Piek JJ, Pugliese F, Rubboli A, Semb AG, Senior R, Ten Berg JM, Van Belle E, Van Craenenbroeck EM, Vidal-Perez R, Winther S; ESC Scientific Document Group. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J. 2024 Sep 29;45(36):3415-3537. https://academic.oup.com/eurheartj/article/45/36/3415/7743115 DISCLOSURES:  Alexander Kharlamov and Pepijn Adriaan Van Diemen have no conflicts of interest to declare.

With Raffaele Scorza, South Hospital Stockholm - Sweden and Riccardo Asteggiano, LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy.    In this podcast*, Raffaele Scorza joins Riccardo Asteggiano to discuss asymptomatic patients with ventricular extrasystoles.   *Technical support provided by Charlie Torstensson.

With Maxime Guenoun, Department of Rhythmology, European Hospital, Marseille - France and Christophe Leclercq, Rennes University Hospital, Rennes - France. In this podcast, Christophe Leclercq joins Maxime Guenoun to discuss how to manage patients with asymptomatic atrial fibrillation.

With Nikolaus Marx, Chair of Task Force of the 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes, RWTH University Hospital Aachen, Aachen - Germany and Ruxandra Christodorescu, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania. In this podcast, Nikolaus Marx joins Ruxandra Christodorescu to discuss updates on heart failure and diabetes: what is the potential role of semaglutide and the combination of GIP-GLP1 receptor agonists in the management of HF?

With Bogdan Timar, University of Medicine and Pharmacy Victor Babes, Timisoara and Diabetes Clinic, "Pius Brinzeu" Emergency Hospital Timisoara - Romania, and Ruxandra Christodorescu, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania.   In this podcast, Bogdan Timar  joins Ruxandra Christodorescu to discuss updates on glucose lowering medication in diabetic patients with cardiovascular and renal diseases.

With Marc Ferrini, CH Saint Joseph and Saint Luc, Lyon - France and Henner Hanssen, University of Basel - Switzerland.   In this podcast, Henner Hanssen joins Marc Ferrini to discuss how to manage obesity-related cardiovascular risk through physical activity and exercise.

With Marc Ferrini, CH Saint Joseph and Saint Luc, Lyon - France and Massimo Volpe, Sapienza University of Rome - Italy In this podcast, Massimo Volpe joins Marc Ferrini to discuss how to manage obesity and its related cardiovascular risk.  

With Konstantinos Toutouzas and Charalambos Vlachopoulos, First Department of Cardiology of the National & Kapodistrian University of Athens - Greece.  Konstantinos Toutouzas and Charalambos Vlachopoulos discuss cardiac amyloidosis.  

With Riccardo Asteggiano, Laboratorio Analisi Ricerca Clinica, Turin - Italy and Daniel Lenihan, Saint Francis Healthcare System, Cape Girardeau, MO - USA.   In this podcast, Daniel Lenihan joins Riccardo Asteggiano to discuss cardiac amyloidosis and internal medicine.

With Riccardo Asteggiano, Faculty of Medicine, Insubria University, Varese, and LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy, and José Fernando Rodriguez Palomares, Vall d'Hebron University Hospital, Barcelona - Spain.   In this podcast, José Fernando Rodriguez Palomores joins Riccardo Asteggiano to discuss the new 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases, focusing on aortic aneurysms.

With Thomas F. Luscher, ESC President, Royal Brompton Hospital Imperial College London - UK and Center for Moelcular Cardiology, University of Zurich - Switzerland, and Marc Ferrini,  Editor-in-Chief Cardio Practice, CH Saint Joseph and Saint Luc, Lyon - France.   In this podcast, Thomas F. Luscher joins Marc Ferrini to discuss his plans and vision for the future in his new role as President of the ESC.

With Ruxandra Maria Christodorescu, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania and Eva Gerdts, University of Bergen - Norway.   In this podcast, Eva Gerdts joins Dr Ruxandra Christodorescu to discuss essential hypertension from the 2024 Guidelines for the management of elevated blood pressure and hypertension (https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehae178/7741010).

With Tiziana Claudia Aranzulla, MD, MSC, Mauriziano Umberto Hospital, Turin - Italy, and Ruxandra Maria Christodorescu, MD, PhD, FESC, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania.     In this podcast, Tizania Claudia Aranzulla joins Ruxandra Christodorescu to discuss acute coronary syndrome in women.

With Tiziana Claudia Aranzulla, MD, MSC, Mauriziano Umberto Hospital, Turin - Italy, and Riccardo Asteggiano, MD, FESC, Laboratorio Analisi Ricerca Clinica, Turin - Italy.   In this podcast, Tizania Claudia Aranzulla joins Riccardo Asteggiano to discuss acute coronary syndrome in elderly and frail patients.

With Martine Gilard, MD, PhD, FESC, ex-President of French Society of Cardiology and President-elect EAPCI, Hospital Cavale Blanche, Brest - France, and Riccardo Asteggiano, MD, FESC, LARC (Laboratorio Analisi Ricerca Clinica), Turin - Italy   In this interview, Martine Gilard joins Riccardo Asteggiano to discuss the long-term follow-up of patients with acute coronary syndrome. The main aspects of secondary prevention and of clinical control are debated and a clear indication of the follow-up of these complex patients in General Cardiology are given.

In this interview with Borja Ibáñez, National Centre for Cardiovascular Research CNIC and Fundacion Jimenez Diaz Hospital, Madrid - Spain, one of the Task Force co-ordinators of the ESC 2023 Guidelines for the management of acute coronary sydromes, and Riccardo Asteggiano, Laboratorio Analisi Ricerca Clinica, Turin - Italy, underline the complex aspects of long-term therapy after ACS, mainly concerning antithrombotic management and secondary prevention management.

With Bernard Iung, Hospital Bichat-Claude Bernard, Paris - France & Konstatinos Toutouzas, National & Kapodistrian University of Athens, Athens - Greece. In this podcast, they discuss primary mitral regurgitation.

With Maurice Enriquez-Sarano, The Allina Heart Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, MN & Marc Ferrini2, CH Saint Joseph and Saint Luc, Lyon, France. In this podcast, Dr Maurice Enriquez-Sarano (The Allina Heart Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, MN, USA) joins Dr Marc Ferrini (Editor-in-Chief CardioPractice; CH Saint Joseph and Saint Luc, Lyon, France) to discuss our current understanding of mitral valve prolapse (MVP). The treatment of MVP has evolved in recent years, and we now know that a small fraction of myxomatous mitral valve prolapse patients may, over time, experience severe arrhythmia, irrespective of mitral regurgitation severity. Dr Sarano presents the current thinking on the diagnosis and the tools available for arrhythmic risk stratification.

With João Bicho Augusto, Hospital Professor Doutor Fernando Fonseca, Amadora - Portugal, Institute of Cardiovascular Science, University College London, London - United Kingdom & Victoria Johnson, University Hospital Frankfurt, Frankfurt am Main - Germany. In this podcast, Dr João Bicho Augusto (Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal & Institute of Cardiovascular Science, University College London, London, United Kingdom) joins Dr Victoria Johnson (University Hospital Frankfurt, Frankfurt am Main, Germany) to discuss his CardioPractice article: Artificial intelligence in cardiovascular imaging algorithms - what is used in clinical routine?

With Panos E. Vardas, Department at Heraklion University, Hospital, Crete - Greece & Marc Ferrini, Editor-in-Chief CardioPractice; CH Saint Joseph and Saint Luc, Lyon - France. In this podcast, Professor Panos E. Vardas (Department at Heraklion University, Hospital, Crete, Greece) joins Dr Marc Ferrini (CH Saint Joseph and Saint Luc, Lyon, France) to discuss how artificial intelligence can modify our daily cardiology practice.

With Nicolaus Marx, WTH University Hospital Aachen, Aachen - Germany & Ruxandra Christodorescu, University of Medicine and Pharmacy Victor Babes, Timisoara - Romania.   In this podcast, Professor Nicolaus Marx (WTH University Hospital Aachen, Aachen, Germany), Chair of Task Force of the 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes;  joins Associate Professor Ruxandra Christodorescu (University of Medicine and Pharmacy Victor Babes, Timisoara, Romania) to discuss lipids and diabetes.

With Dimitris RICHTER, Euroclinic of Athens, Athens - Greece & Heinz DREXEL, Vorarlberg Institute for Vascular Investigation and Treatment, Feldkirch - Austria. In this podcast, Professor Heinz Drexel (Vorarlberg Institute for Vascular Investigation and Treatment, Feldkirch, Austria) joins Dr Dimitris Richter (Euroclinic of Athens, Athens, Greece) to discuss hypertriglyceridemia and residual cardiovascular risk.   Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk. N Engl J Med. 2022 Nov 24;387(21):1923-1934. Sosnowska B, Adach W, Surma S, Rosenson RS, Banach M. Evinacumab, an ANGPTL3 Inhibitor, in the Treatment of Dyslipidemia. J Clin Med. 2022 Dec 25;12(1):168. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821629/ Gaba P, Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, Ketchum SB, Juliano RA, Jiao L, Doyle RT Jr, Granowitz C, Tardif JC, Giugliano RP, Martens FMAC, Gibson CM, Ballantyne CM; REDUCE-IT Investigators. Prevention of Cardiovascular Events and Mortality With Icosapent Ethyl in Patients With Prior Myocardial Infarction. J Am Coll Cardiol. 2022 May 3;79(17):1660-1671. https://www.sciencedirect.com/science/article/pii/S0735109722005538?via%3Dihub Drexel H, Tamargo J, Kaski JC, Lewis BS, Saely CH, Fraunberger P, Dobrev D, Komiyama M, Plattner T, Agewall S, Hasegawa K. Triglycerides revisited: is hypertriglyceridaemia a necessary therapeutic target in cardiovascular disease? Eur Heart J Cardiovasc Pharmacother. 2023 Sep 20;9(6):570-582. https://academic.oup.com/ehjcvp/article/9/6/570/7199773?login=false ACCORD Study Group; Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein HC, Probstfield J, Grimm RH, Ismail-Beigi F, Bigger JT, Goff DC Jr, Cushman WC, Simons-Morton DG, Byington RP. Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med. 2010 Apr 29;362(17):1563-74. https://www.nejm.org/doi/10.1056/NEJMoa1001282?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov