Gyno Gurus Podcast
by gynoguruspodcast
Alexandra MacLean, WHNP-BC, and Peter Mandel, MD, FACOG, are women’s health clinicians and co-hosts dedicated to translating medical evidence into clear, practical guidance. Their conversations help listeners understand their bodies, ask better questions, and make confident decisions—without the jargon.
Episodes
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PCOS IS EXTINCT!!!
In this episode of the Gyno Gurus Podcast, we break down the emerging concept of PMOS (Polyendocrine Metabolic Ovarian Syndrome) and why many experts believe the term “PCOS” may no longer fully capture what’s really happening in the body. We explore how genetics, epigenetics, insulin resistance,...
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PCOS Explained (Part 1): What It Is, How It's Diagnosed, & Why It's Misunderstood
If you’ve ever been told you have PCOS—or think you might—you’re not alone… but you may not have gotten the full picture. In Part 1 of this PCOS series, we break down what PCOS actually is (and what it isn’t), why it’s called a syndrome, and how it’s diagnosed in real clinical practice. We also...
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Fact or Fiction - PMS, Is It All In Your Head?
Is PMS really “all in your head”? 🤔 In this Fact or Fiction episode of the Gyno Gurus Women’s Health Podcast, we break down one of the most dismissive myths in women’s health—and replace it with actual physiology. We dive into what’s really driving PMS and PMDD, from hormonal signaling and...
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Fact or Fiction - Part 1
Can you get pregnant on your period? Is Natural Family Planning only for women with “perfect” cycles? Does birth control protect—or harm—future fertility? In this Fact or Fiction episode of the Gyno Gurus Podcast, we break down three of the most common fertility myths. We’ll walk through how the...
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Human Papillomavirus (HPV) - Everything you Need to Know
Human Papillomavirus (HPV) is one of the most common sexually transmitted infections—but there’s a lot of confusion, fear, and misinformation surrounding it. In this episode of The Gyno Gurus Podcast, we break down HPV in a clear, evidence-based, and patient-centered way. We cover what HPV…
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Get to Know Your Thyroid
Unlock the essentials of hypothyroidism, thyroid optimization, Hashimoto’s, and evidence-based treatment options in this deep-dive episode. Whether you're a clinician, patient, or someone trying to understand thyroid health, this video breaks everything down in a clear, practical way. We cover…
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FDA Update: Hormone Replacement Therapy - What You Need to Know
The FDA has officially begun removing the long-standing Black Box warnings from Hormone Replacement Therapy (HRT) products — a major shift after more than two decades of confusion, fear, and misinformation. In this video, we break down what this change means, why it’s happening now, and how it...
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Insulin Resistance Part 4: Allulose, Metformin, & GLP-1s (Ozempic)
In this episode, we break down three of the most talked-about tools in metabolic health — Allulose, Metformin, and GLP-1 agonists (like Ozempic) — and explore how each impacts insulin resistance, glucose regulation, and metabolic health. We start with a clear overview of insulin resistance, then...
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Insulin Resistance: Exercise, Life Style, and Supplements (Myo-inositol & Berberine)
🧠 Insulin Resistance: Exercise, Lifestyle, and Supplements (Myo-Inositol & Berberine) In this episode, we break down how exercise, nutrition, and evidence-based supplements can improve insulin sensitivity and metabolic health. Learn how muscle mass, time-restricted feeding, and protein intake…
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Clinical Conversations: When Blood Sugar Meets Hormones
In this Clinical Conversations episode, we bring insulin resistance to life through a real patient story — showing how disrupted blood sugar balance can ripple through a woman’s hormonal cycle. We walk through her cycle charts, hormone patterns, and lab results, including fasting insulin…
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Insulin Resistance Explained (Part 2) - Why it Happens, Signs to Watch, and How to Test for It
Today we’re breaking down insulin resistance — what it really means, why it happens, and how you can spot it early. We’ll walk through what’s actually going on in your body when your cells stop responding to insulin, how that leads to cravings, fatigue, and weight gain, and which tests can help…
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Insulin Resistance Explained (Part 1)
Insulin Resistance: What it is, how to test it, and evidence-based ways to improve it. In this episode we break down insulin’s role in metabolism, the difference between normal vs optimal glucose/insulin ranges, the most useful labs (and how to read them), and practical strategies that can…
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About this show
Alexandra MacLean, WHNP-BC, and Peter Mandel, MD, FACOG, are women’s health clinicians and co-hosts dedicated to translating medical evidence into clear, practical guidance. Their conversations help listeners understand their bodies, ask better questions, and make confident decisions—without the jargon.
Hosted by
gynoguruspodcast