Health Longevity Secrets
by Robert Lufkin MD
The health advice you're getting isn't working. Want to know what the experts actually do for themselves? Health Longevity Secrets reveals the real science behind longevity, metabolic health, fasting, and disease reversal—the protocols that researchers and physicians use in their own lives, not just what they tell patients. Robert Lufkin MD is a medical school professor, practicing physician, and New York Times bestselling author. After reversing his own chronic disease through lifestyle medicine, he's on a mission to share what actually works. Each episode features in-depth interviews with world-class scientists, doctors, and biohackers who share their personal health strategies—no sponsored talking points, just real answers. Your health transformation starts here.
Episodes
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Elizabeth Holmes's Blood Test Dream Is Coming True Without Her
Elizabeth Holmes went to prison for promising hundreds of blood tests from a single drop of your finger. Some of what she promised is now FDA cleared, and some of it may never be possible at all. With the new documentary You Can See Everything in theaters, Robert Lufkin MD looks at what Theranos...
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EXPLAINER: Did Plague Just Escape From a Russian Lab?
A young scientist died in a Russian plague lab. Officials deny an accident. Is biowarfare a real threat, or is the bigger risk something else? Robert Lufkin MD looks at the death of a young lab worker at Russia's Irkutsk anti-plague institute, why Moscow's denials are hard to take at face value,...
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EXPLAINER: How To Live To 117
She lived to 117 — and when scientists sequenced everything from her genome to her gut bacteria, they found a paradox that rewrites what aging has to look like. In this episode, Robert Lufkin MD breaks down the landmark multiomics study of Maria Branyas Morera, the world's oldest verified person,...
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Ozempic Face: Why Weight Loss Can Make You Look Older | Kay Durairaj MD
A facial plastic surgeon reveals the MRI data on "Ozempic face," why repeated masseter Botox can thin the jawbone, and the topical rapamycin resetting skin cells to a 20-year-old phenotype. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. Kay Durairaj, a USC and...
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EXPLAINER: Will AI Cure All Disease?
Will AI cure all disease? 90% of biomedical papers published in December 2025 show signs of AI assistance — and the Nobel laureate behind AlphaFold says AI could help end all disease within a decade. In this episode, Robert Lufkin MD examines what artificial intelligence is really doing to health...
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Ultrasound to Calm the Nervous System | Jon Hacker
Modern technology is tricking your nervous system into fight-or-flight — and it's decently profitable to keep you there. Jon Hacker, CEO of NeurGear, explains how focused ultrasound vagus nerve stimulation can switch you back. In this episode of Health Longevity Secrets, Robert Lufkin MD sits…
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EXPLAINER: Will mRNA Vaccines Cure Cancer?
For the first time in history, a personalized mRNA cancer vaccine has passed a Phase 3 clinical trial. Robert Lufkin MD breaks down the Moderna/Merck melanoma result, how a vaccine custom-built from your own tumor actually works, the 49% drop in recurrence risk behind the headlines — and the…
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The Alzheimer's Lie: It's Not The Amyloid | David Perlmutter MD
Neurologist David Perlmutter MD says the beta-amyloid theory of Alzheimer's is wrong — and the real culprit is your brain's own immune cells. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with the #1 New York Times bestselling author to unpack his new book Brain…
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EXPLAINER: Human Age Reversal Has Begun
They just injected youth genes into a human eye. On June 9, 2026, a patient with glaucoma became the first human ever dosed with ER-100 — an epigenetic reprogramming gene therapy designed not just to slow aging, but to reverse it. In this solo explainer, Dr. Robert Lufkin breaks down the science…
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Your Beliefs Control Your Genes | Bruce Lipton PhD
What if your genes aren't your destiny? Cell biologist Bruce Lipton PhD — the former medical school professor whose cloned stem cell research helped pioneer epigenetics, and author of The Biology of Belief (published in over 50 languages) — joins Robert Lufkin MD to make the case that perception,...
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EXPLAINER: The Longevity IV That Killed a 27-Year-Old
A healthy 27-year-old walked into a Bronx wellness center for an NAD+ "longevity infusion" — and was dead within the hour. The man holding the needle wasn't licensed to practice medicine anywhere in the US. Robert Lufkin MD breaks down the Elizabeth Baron case: what actually happened, what NAD+…
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Heart Surgeon: It's Not Cholesterol — It's Metabolic Health | Philip Ovadia MD
A cardiac surgeon who's performed thousands of open-heart operations says most of his patients didn't have to be there — and the culprit isn't cholesterol, it's metabolic health. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. Philip Ovadia, board-certified…
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There's No Such Thing as a Weight Problem | Ben Azadi
"There's no such thing as a weight problem — it's a weight symptom." Ben Azadi joins Robert Lufkin MD to dismantle the calorie myth and reveal the metabolic root cause underneath stubborn fat, fatigue, and disease. Ben Azadi — functional health practitioner, founder of Keto Camp, and bestselling...
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The Nerve in Your Ear That Controls Stress | Jane Ollis (Sona)
What if a single nerve in your ear could shift you out of fight-or-flight in 10 minutes? Jane Ollis explains why your vagus nerve and HRV may be the most overlooked levers for stress, sleep, and longevity. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Jane Ollis —...
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EXPLAINER: Glucosamine and Alzheimer's: Protection or Poison?
The same glucosamine pill millions take for joint pain may protect a healthy brain — and accelerate Alzheimer's in a brain already in decline. Here's the science. In this episode of Health Longevity Secrets, Robert Lufkin MD breaks down the 2026 plot twist on glucosamine and dementia: why a...
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What If The Pain Is Actually The Fuel? | Ben Barbic
What if the pain you've been trying to escape is actually the fuel you've been looking for? Recording artist Ben Barbic walked away from alcohol, nicotine, and blood pressure medications at 28 — and built a 15-year operating system for resilience. In this episode of Health Longevity Secrets…
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EXPLAINER: Does Creatine Cause Cancer? What the Science Actually Says
Creatine causes cancer to spread — that headline is built on a real mouse study. But what does the human data actually say? In this solo explainer, Dr. Robert Lufkin breaks down both halves of the science behind the most studied supplement on the planet. He walks through the 2021 mouse metastasis...
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The Smart Toilet That Could Detect Cancer Before You Know You Have It | Scott Hickle (Throne)
Colorectal cancer is now the #1 cancer killer in Americans under 50 — and roughly 60% of cases are diagnosed at stage III or IV. What if your toilet could spot the earliest sign years before symptoms? Robert Lufkin MD sits down with Scott Hickle, co-founder and CEO of Throne Science, to talk…
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EXPLAINER: Sleep Isn't For Muscle Repair — Here's What It's Actually For
Forget muscle repair. The reason sleep actually transforms your health is happening inside your skull every night — and it's not what Matthew Walker's TED Talk made famous. In this episode of Health Longevity Secrets, Robert Lufkin MD breaks down the real science of sleep: the glymphatic system...
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Are We In A Longevity Revolution? — David Donnelly (Director, Forever Young)
What if the longevity revolution isn't really a science problem, but a human one we're completely unprepared for? In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with David Donnelly — the award-winning filmmaker behind "Forever Young" (winner of the Mill Valley Film…
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EXPLAINER: ANKTIVA- The Next Great Longevity Drug?
There's a single number on your routine blood test that predicts your risk of dying from cancer, heart disease, and infection better than cholesterol — and an FDA-approved drug may now move it. In this Health Longevity Secrets explainer, Robert Lufkin MD breaks down lymphopenia, the IL-15…
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The Army Ranger Who Found Magic Mushrooms Save Lives — Neil Markey (Beckley Retreats)
What if the same symptoms we see in combat veterans — the broken sleep, the irritability, the brain fog — were already quietly spreading through the healthiest, highest-performing people you know? In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Neil Markey — a former…
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EXPLAINER: 5 Longevity Myths the Latest Science Has Debunked
Five longevity beliefs that millions have followed for decades have just been overturned by the latest research. Some of these will surprise you. In this explainer, Robert Lufkin MD walks through five of the most widely believed longevity myths — and what the most recent science actually says…
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Perimenopause Is the Inflection Point Breaking Women's Health — Dr. Mayoni Gooneratne
What if the most dangerous metabolic inflection point in a woman's entire life is the one we've been taught to simply endure? In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. Mayoni Gooneratne — a London-trained former NHS colorectal and pelvic floor surgeon, now…
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EXPLAINER: What Happens to Your Body in 5 Days Without Ultra-Processed Food
Ultra-processed food makes up over half the calories Americans eat - and over 60% for kids. Here's what the research shows happens inside your body in the first 5 days after you quit. In this episode of Health Longevity Secrets, Dr. Robert Lufkin walks through the hour-by-hour timeline: the…
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The 91-Year-Old Physicist Betting His Body on Mitochondrial Transplant | John Cramer PhD
What if aging isn't a hundred separate problems but a single one — an energy crisis inside the tiny power plants of every cell? At 91, Dr. John G. Cramer is betting his own body on the answer. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. John G. Cramer —…
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EXPLAINER: 3 Blood Tests Your Doctor Skips (That Predict Heart Attacks & Alzheimer's)
Your doctor orders a lipid panel every year — but 3 cheap blood tests predict heart disease, diabetes, and even dementia far better than cholesterol, and most doctors never order them. In this episode, Robert Lufkin MD walks through fasting insulin + HOMA-IR, homocysteine, and high-sensitivity…
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Your Phone Is Rewriting Your Biology — Daniel DeBaun (Former Bell Labs Engineer)
What if the single device you hold closest to your body for 10+ hours a day is quietly rewriting your biology — and your grandchildren's? In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Daniel DeBaun — a former Bell Labs and AT&T telecom engineer who helped build the...
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EXPLAINER: Medicine's Forgotten Biomarker - The Homocysteine Story Your Doctor Missed
In 1969, Harvard pathologist Kilmer McCully discovered elevated homocysteine causes arterial damage and heart disease. He was forced out of Harvard. The Framingham Heart Study confirmed him. Then the AHA buried it anyway. CHAPTERS: 00:00 - McCully discovery and suppression 01:20 - Part 1: What...
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AI-Powered Longevity Science — One Gene to Reverse Aging? | Daniel Ives PhD
What if an AI could run centuries of aging experiments in a year? Dr. Daniel Ives, CEO of Shift Bioscience, explains how his team used a virtual cell to discover SB000 — a single gene that matches Yamanaka factor rejuvenation without cancer risk. CHAPTERS: 00:00 — Centuries of experiments in a…
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EXPLAINER: 90% of Americans Have This Disease — And Most Have Never Heard of It
In October 2023, the American Heart Association officially admitted something that changes everything: heart disease, kidney disease, and diabetes are not separate conditions — they're one syndrome. CKM syndrome. And 90% of US adults already have it. CHAPTERS: 00:00 — 90% of Americans have this...
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Keto Saved My Life — The Future of Metabolic Medicine | Nick Norwitz PhD MD
A ketogenic diet put his ulcerative colitis into complete remission — off all medications, confirmed on colonoscopy. Dr. Nick Norwitz (PhD Oxford, MD Harvard) explains why evidence-based care isn't always optimal care, how keto rewires the gut and brain, and why GLP-1 drugs should catalyze...
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EXPLAINER: The Magnesium LIE — Why Your Blood Test Is Missing 99% of the Problem
Your doctor says your magnesium is normal. But that test measures less than 1% of your body's total magnesium. Nearly half of US adults are deficient in the mineral required for 600+ enzymatic reactions, every ATP molecule, insulin signaling, blood pressure, heart rhythm, and sleep. CHAPTERS…
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Can a Transplant Cure Aging? | Catherine Baucom MD PhD
Imagine treating chronic disease by restoring the cell's energy engines rather than chasing symptoms. That's the bet behind mitochondrial organelle transplantation — delivering healthy donor mitochondria to failing tissues. CHAPTERS: 0:00 - Introduction 2:02 - Mitochondrial Transplantation...
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EXPLAINER: Walking Won't Burn Fat (Here's What It Actually Does)
Walking videos are everywhere — "walk 10,000 steps and melt belly fat." The conclusion is right: walking does reduce body fat. But the explanation is completely wrong. Your body compensates for ~80% of exercise calories. The real reason walking transforms metabolic health has almost nothing to do...
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The Longevity Nerve: The Missing Link in Stress, Aging & Brain Health | Elisabetta Burchi MD
What if one nerve quietly connects your brain to your heart, gut, immune system, and even how long you live? Dr. Elisabetta Burchi explains why the vagus nerve may be the missing link in stress resilience, cognition, and longevity. CHAPTERS: 0:00 - The vagus nerve and longevity medicine 0:27…
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A Glucose Sensing Watch | Sabih Chaudhry PhD
Ever wished continuous glucose data didn’t require needles, adhesives, or a prescription? We sit down with Sabih Chaudhry, PhD, founder of AFON Technology, to unpack GlucoWare—a wrist-worn, noninvasive glucose wearable that uses low-power RF signals to read blood in near real time. Instead of...
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The $101 Million Race to Solve Longevity | Jamie Justice PhD
Dr. Jamie Justice is the Executive Director of XPRIZE Healthspan - a $101 million, 7-year global competition to extend human healthspan by developing therapies that restore muscle, cognitive, and immune function by 10 to 20 years in people over 50. She is also a leading geroscientist and Adjunct...
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How To Reverse Alzheimer's | Heather Sandison ND
Dr. Heather Sandison was told in medical school that suggesting you could help someone with Alzheimer's was promoting false hope. Then she ran a clinical trial and 74% of participants with measurable cognitive impairment improved in six months. In this episode, Dr. Sandison breaks down the five...
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The Sugar Addiction Lie | Christine Trimpe
Christine Trimpe was morbidly obese, pre-diabetic, and couldn't walk a half-mile mountain trail. Ten years later, she's lost over 100 pounds, reversed fatty liver disease and sleep apnea, and coaches thousands of women through metabolic healing - all by quitting sugar. In this episode, Christine...
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We’re Not Sick. We’re Being Sold | David Etheridge
A high calcium score, a stack of prescriptions, and the nagging sense that “healthy eating” wasn’t working—David Etheridge’s story captures what millions feel but rarely decode. When he shifted from chasing calories to controlling insulin, everything changed: he moved from a 12:12 rhythm to a…
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Why Am I Always Hungy? | Jason Fung MD
What if the real lever for lasting weight loss isn’t calories, but hunger itself? We sit down with Dr. Jason Fung to unpack why willpower-based diets fail and how hormones like insulin, cortisol, GLP-1, and sympathetic tone quietly set your “fat thermostat.” Instead of fighting biology, we…
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Why Your Brain Doesn’t Have to Age | Majid Fotuhi MD
Think your brain has to slow down with age? We push back hard with science, stories, and a step-by-step plan that has helped patients regain clarity in weeks, not years. Our guest, Dr Majid Fotuhi, a Harvard- and Hopkins-trained neurologist who has treated thousands of patients, explains why…
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The Movie Amazon Doesn’t Want You to See | Vinny Lingham
A tech founder’s health fell apart, and the fix didn’t come from a supplement stack or another glossy wellness trend. It started with a hard look at seed oils, blood sugar spikes, and the way ultra-processed “healthy” foods quietly inflame the body. That reckoning led Vinny Lingham to the…
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Ancient Health Secret Revealed | Shivani Gupta PhD
Pain that creeps in, brain fog that lingers, weight that resists every effort—what if the culprit isn’t “just getting older,” but inflammaging? We sit down with Dr. Shivani Gupta, author of The Inflammation Code, to connect ancient Ayurvedic wisdom with modern science and map out a practical plan...
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How Ancestral Wisdom Transforms Our Health
What if the most powerful biohack is simply getting the morning sun in your eyes and letting your wearables prove it works? We explore Medicine 4.0 with Steven Stavrou DCM, a South African physician-biohacker who blends Chinese and functional medicine with hard data, showing how ancestral habits...
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When ‘Normal Labs’ Are Unhealthy | Sandeep Palakodeti MD
Feeling “fine” is not a plan. We sit down with Dr Sandeep Palakodeti —an Ivy League–trained internist who left elite institutions—to unpack why so much of healthcare reacts to disease instead of building durable health, and how treating your body like your ultimate asset can change the arc of…
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Is Oxygen the Root Cause of Chronic Disease?
What if the core of fatigue, brain fog, and “getting old” is really an oxygen problem? We sit down with Brad Pitzele to unpack how exercise with oxygen therapy (EWOT) and red and near-infrared light can reboot cellular energy, open microcirculation, and dial down inflammation in a way that’s…
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What if the Future of Medicine is in Your Home?
What if the most powerful health checkup you ever had happened at your kitchen table, not a clinic? We sit down with Dr. Natasha Milinkovic, a UK physician who moved from the front lines of vascular surgery and emergency medicine to the leading edge of preventive care, to explore how lab‑grade...
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What If a ‘Good Sugar’ Could Improve Alzheimer’s?
What if the most powerful “sugars” aren’t fuel at all, but messages your immune system has been waiting to hear? We sit down with Dr John Lewis, a former professor whose lab uncovered striking cognitive improvements in people with moderate to severe Alzheimer’s after 12 months on a formula built...
About this show
The health advice you're getting isn't working. Want to know what the experts actually do for themselves?
Health Longevity Secrets reveals the real science behind longevity, metabolic health, fasting, and disease reversal—the protocols that researchers and physicians use in their own lives, not just what they tell patients.
Robert Lufkin MD is a medical school professor, practicing physician, and New York Times bestselling author. After reversing his own chronic disease through lifestyle medicine, he's on a mission to share what actually works.
Each episode features in-depth interviews with world-class scientists, doctors, and biohackers who share their personal health strategies—no sponsored talking points, just real answers.
Your health transformation starts here.
Hosted by
Robert Lufkin MD