PODCAST · health
Healthspan
by Michael Salzle
Become a Paid Subscriber: https://podcasters.spotify.com/pod/show/michael-salzle/subscribeHealthspan. The podcast that will add years to your life, and life to your years
Episodes
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96. Empagliflozin in Patients with Chronic Kidney Disease
https://www.nejm.org/doi/full/10.1056/NEJMoa2204233
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95. Tirzepatide Once Weekly for the Treatment of Obesity
SURMOUNT 1 Trial. The aim of this trial was to investigate the safety and efficacy of Tirzepatide, a novel GLP + GIP in people with obesity. We discuss the trial in this episode.
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94. Effects of Semaglutide on CKD in Patients with Type 2 Diabetes
@ michaelsalzle Patients with diabetes and chronic disease are at high risk for kidney failure, cardiovascular events, and death. The FLOW trial looked at the safety and efficacy of semaglutide in patients with chronic disease and type 2 diabetes.
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93. How Not To Age, by Dr. Michael Greger - Part 6. Preservation 2
@michaelsalzle Preservation of your immune system, mind, and muscle
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92. How Not To Age, by Dr. Michael Greger - Part 5. Preservation
@michaelsalzle In this episode, we learn how to preserve our bones, bowel, circulation, hair, hearing, and hormones.
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88. How Not To Age, by Dr. Michael Greger - Part 1. AMPK, Senescence, Autophagy, and Epigenetics
@michaelsalzle. In this episode, we discussed pathways of aging. We discuss the importance of genes, AMPK, autophagy, metformin, foods that boost AMPK, autophagy, foods that boost autophagy, spermidine,epigenetics, and cellular senescence
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87. Outlive, by Dr. Peter Attia - Part 11. Emotional Health
@michaelsalzle
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85. Outlive, by Dr. Peter Attia - Part 9. Nutrition 3.0 (part 1)
@michaelsalzle. In this episode we discuss nutrition 3.0. Epidemiology, clinical trials. The Mediterranean diet, the University of Wisconsin CR trial vs the NIH CR trial, carbohydrates, and protein.
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83. Outlive, by Dr. Peter Attia - Part 7. Exercise, the Centenarian Decathlon, and Zone 2 training
IG: @michaelsalzle. In this episode, we go into the broad topic of exercise. Exercise is considered the most powerful longevity drug. We review studies that underscore the importance of exercise. We also discuss the centenarian decathlon, and take a deep dive into zone 2 training.
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77. Outlive, by Dr. Peter Attia - Part 1. The four horseman, fast death, slow death, and longevity
@michaelsalzle. The Long Game
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76. The History of Rapamycin and mTOR. David Sabatini’s journey to discovering mTOR.
https://www.pnas.org/doi/10.1073/pnas.1716173114 @michaelsalzle
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72. Metformin in Aging and Aging - Related Diseases, by Chen et al - Part 2
@michaelsalzle Metformin and it’s effect on the hallmarks of aging https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965502/#abstract-1title
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71. Metformin in Aging and Aging - Related Diseases, by Chen et al - Part 1
@michaelsalzle. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965502/#abstract-1title
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70. The Immunity Code, by Joel Greene - Part 3. Young blood, bifidobacteria, butyrate, akkermansia
@michaelsalzle. In this episode, learn about how to keep your muscle and blood young, circadian rhythm, bifidobacterium, butyrate, akkermansia, and keeping a strong gut lining.
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68. The Immunity Code, by Joel Greene - Part 1. Inflammaging, peak physiology, and our 3 genomes
@michaelsalzle. https://www.cell.com/cell/fulltext/S0092-8674(22)01570-7 a link to David Sinclair’s new paper I referenced in this episode
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67. Win, by Dr James Dinicloantonio - Part 4. Supplements for Athletic Performance and Health
@michaelsalzle in this episode I discuss the best supplements for athletic performance, the different types of protein, creatine, inositol, Amino Acids, caffeine, etc.
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66. Win, by Dr. James Dinicloantonio - Part 3. Obesity, weight loss, satiety and hunger hormones
@michaelsalzle. Learn more about obesity, weight loss, hormones, calories in vs. calories out, importance of protein in muscle sparing, and metabolic rates
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64. Win, by Dr. James Dinicloantonio - Part 1. Using cold and hot therapy to improve your healthspan
@michaelsalzle. Hot and cold protocols for improving performance, recovery, and overall health. Using glaborous skin to your advantage and the role of AVA‘s, the benefits of pre-exercise cooling, negative effects of cold exposure on exercise performance and adaptation, and heat exposure/heat…
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63. True Age, by Dr. Morgan Levine - Part 5
@michaelsalzle. Exercise, sleep, and future innovations in the field of aging (CR mimetics, senolytics, young blood, and yamamaka factors)
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62. True Age, by Dr. Morgan Levine - Part 4
@michaelsalzle. IGF, protein restriction, FMD, TRE, 5:2 and ADF
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61. True Age, by Dr. Morgan Levine - Part 3
@michaelsalzle. The benefits of calorie restriction and slowing our biological age
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60. True Age, by Dr. Morgan Levine - Part 2
@michaelsalzle. Ways to measure your biological age
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59. True Age, by Dr. Morgan Levine - Part 1
@michaelsalzle. Biological age vs. chronological age, and the importance of making aging a disease. She also reviews the different hallmarks of aging
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58. Drop Acid, by Dr. David Perlmutter - Part 3
@michaelsalzle supplements to lower uric acid, CGM importance, and the importance of time restricted eating.
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57. Drop Acid, by Dr. David Perlmutter - Part 2
@michaelsalzle. Uric Acid and the link with Alzheimer’s disease, sleep and uric acid, and other instigators of elevated uric acid
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56. Drop Acid, by Dr. David Perlmutter - Part 1
@michaelsalzle. Uric Acid- what it is, where it comes from, and how its implicated in many diseases including HTN, diabetes, NAFLD, Alzheimer’s, and much more.
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55. Life Force, by Tony Robbins - Part 3
@michaelsalzle Diabetes, Obesity, and Alzheimer’s therapeutics
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54. Life Force, by Tony Robbins - Part 2
@michaelsalzle Peptide, Key nutraceuticals like Metformin and NAD, hormones, fasting, time restricted eating, and the healing powers of hot and cold
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53. Life Force, by Tony Robbins - Part 1 (continued)(updated)
@michaelsalzle. AI diagnostics, anti aging, CAR T cell therapy, CRISPR, and the WNT signaling pathway
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52. Life Force, by Tony Robbins - Part 1
@michaelsalzle. Introductory episode. Why Tony Robbins is writing a book about regenerative technology, diagnostic breakthroughs, and anti aging. I also discuss the power of stem cells.
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51. Why We Sleep, by Dr. Matthew Walker - Part 4
@michaelsalzle. Sleep disorders, alcohol and sleep, temperature and sleep, the dark side of sleeping pills, and sleep in healthcare
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50. Why We Sleep, by Dr. Matthew Walker - Part 3
@michaelsalzle. Dreaming, Freud, the purpose of dreaming, nghtmres, ptsd, and dreaming for creativity
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49. Why We Sleep, by Dr. Matthew Walker - Part 2
@michaelsalzle. Sleep for learning and memory. And sleep and it’s association with Alzheimer’s, CVD, and Cancer
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48. Why We Sleep, by Dr. Matthew Walker - Part 1 (continued)
@michaelsalzle. The four differences in sleep across species, sleep before birth, sleep and its possible association with ASD, childhood sleep, and sleep in midlife and old age and why it decreases so substantially
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47. Why We Sleep, by Dr. Matthew Walker - Part 1
@michaelsalzle. In this episode, I cover What sleep is, what sleep isn’t, caffeine, melatonin, sleep pressure, the sleep cycle, defining and generating sleep, NREM and REM
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46. Dirty Genes, by Ben Lynch - Part 2 (continued)
@michaelsalzle. GST, NOS3, and PEMT
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