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Itchy and Bitchy

PODCAST · health

Itchy and Bitchy

Nurse practitioner Karen Nickell discusses the realities of menopause and the female midlife in a way that is both informative and fun.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  1. 215

    Estrogen Has Been Let Out of Jail!

    Karen is joined by future Itchy and Bitchy hosts Stephen Miller, an acute care nurse practitioner specializing in cardiovascular disease, and Dr. Keith Hnilica, a veterinary dermatologist, for a wide-ranging conversation about estradiol and hormone replacement therapy. They discuss the recent removal of the FDA black box warning from most menopausal hormone therapy products and the long shadow of the Women’s Health Initiative study.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  2. 214

    Dining with Your Dog: No Kibble Needed

    Family nurse practitioner Karen Nickell introduces future Itchy and Bitchy host Dr. Keith Hnilica, a veterinary dermatologist, for a lively conversation about pet food and what animals can teach us about wellness. They dig into GLP-1 drugs for pet obesity, the links between processed kibble, gut inflammation, and skin issues, why fresh or Mediterranean-style diets may be better for dogs.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  3. 213

    Can Heartbreak Physically Break Your Heart?

    Karen kicks off a new chapter for Itchy and Bitchy by introducing future host Stephen Miller, a cardiology nurse practitioner, for a conversation on Takotsubo cardiomyopathy, or “broken heart syndrome.” Together they explain what this stress-triggered heart condition is, why it so often affects postmenopausal women, and what recovery can look like.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  4. 212

    Vaginal Biofilm: Stranger Than Fiction!

    Karen answers a listener's question about vaginal biofilms. What are they and why do they make recurrent BV and yeast infections so hard to treat? She explains how these bacterial or fungal communities form protective layers that resist standard treatment, reviews options that may help break the cycle and looks at at-home microbiome testing.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  5. 211

    How to Reset Distress to Peace and Joy (RERUN)

    Karen shares a collection of grounding techniques to help listeners manage stress, anxiety, and negative emotions. From holding ice, savoring food, and taking mindful walks to laughter, music, anchoring exercises, the 5-4-3-2-1 method, and even the calming power of pets, Karen offers tools to help listeners return to the present moment, ease stress, and reconnect with a sense of safety and calm.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  6. 210

    AI in Medicine: Friend or Foe?

    Karen explains how AI is already being used in healthcare, from helping find polyps during colonoscopies to speeding documentation. She also covers the biggest concerns, including the possibility of errors, bias, privacy risks, and over-reliance.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  7. 209

    Digital Health: The New Wild, Wild West

    Karen unpacks the fast-growing world of digital health, from Apple Watch and smartphone apps to telehealth and new hospital tech that can improve care and streamline recovery at home. She also addresses the downsides, raising concerns around the security of these technologies.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  8. 208

    Healing After Pet Loss: A Personal Tale

    Karen shares a deeply personal episode on the human-animal bond after the loss of her family’s lovebird, Saki, exploring why pet grief can feel so profound and practical ways to heal. She offers suggestions, from letting yourself feel what you feel to creating memorial rituals, revisiting joyful memories, and caring for your body while you mourn, plus when to seek professional support.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  9. 207

    Grandmothers Rule: Menopausal Mammals Revisited

    Karen Nickell revisits menopausal mammal, this time with brand new context: new research from Uganda’s Ngogo chimpanzees shows some chimps experience menopause too. She explains what makes humans evolutionary outliers, unpacks the grandmother hypothesis, and explores why certain toothed whales (like orcas) stop reproducing yet continue to live for decades.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  10. 206

    GLP-1: Not Just a Weight Loss Med

    Karen takes a look at GLP-1 receptor agonists, best known for weight loss and diabetes. She explores the rapidly expanding list of conditions these medications may help treat. From emerging and sometimes conflicting research on Parkinson’s and Alzheimer’s disease to FDA-approved benefits for cardiovascular health, kidney disease, and fatty liver disease, Karen breaks down what the science currently shows and where caution is still needed.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  11. 205

    Countdown of Karen's Top Ten Episodes of 2025

    Karen counts down her top 10 Itchy & Bitchy moments of 2025, from smarter New Year’s resolutions and promising UTI vaccines on the horizon to updated insights on HRT.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  12. 204

    Oh, Snap! Osteoporosis!

    Karen shares her personal journey with osteoporosis. What distinguishes it from osteopenia? How are DEXA T-scores interpreted? Why does early screening matter? She covers lifestyle and nutrition, hormone considerations, and medication options.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  13. 203

    Red Light Under My Christmas Tree?

    Karen breaks down red light therapy (photobiomodulation) and where it actually helps: smoothing signs of aging, supporting hair regrowth, calming acne (especially paired with blue light), easing chronic pain and inflammation, and even emerging research for cognition in dementia.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  14. 202

    Holiday Heart Doesn't Mean a Happy Heart (RERUN)

    Family nurse practitioner Karen re-airs a timely episode on “holiday heart syndrome,” the spike in alcohol-triggered arrhythmias (often AFib) that can strike otherwise healthy people during festive gatherings. She explains what binge drinking looks like, key symptoms to watch for (from palpitations and chest pressure to shortness of breath), why it raises stroke risk, and simple prevention steps.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  15. 201

    Surprising Update on Healthcare Self Advocacy!

    After listening to an episode of Itchy and Bitchy, a woman pushed for further testing and caught grade 1A ovarian cancer early—requiring only surgery. Karen revisits why self-advocacy saves lives, translating expert definitions into everyday guidance and offering practical steps: build a true partnership with your provider, keep detailed symptom and medication notes, ask clear questions about tests, risks, and costs, use reliable resources (not “Dr. Google”), consult your pharmacist, and keep your advance care planning up to date.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  16. 200

    Estradiol and Skin: The Perfect Match!

    Karen tackles a common menopause question: oral vs. topical estradiol. She explains first-pass metabolism and why transdermal options can lower clot, gallstone, and side-effect risks for many, then compares real-world choices.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  17. 199

    Redefining Lithium with Low Dosing

    Karen tackles a listener question about low-dose lithium. She reviews micro- vs. low-dose ranges, discusses forms like lithium orotate/aspartate and third-party-tested supplement options, and flags safety essentials such as toxicity symptoms, thyroid/kidney considerations, and when to loop in your clinician.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  18. 198

    Blood Tests for Multiple Cancers + Whole Body Scan Info

    In this update to the August 2024 episode, Karen explains the surge of direct-to-consumer “whole-body” MRI/CT screenings and how to decide with your provider whether they’re a good fit. In the re-aired episode, Karen explores the Galleri test, a multi-cancer early detection (MCED) blood test that can identify over 50 types of cancer. She explains how the test works, its potential benefits, and the risks associated with its use. She also shares personal stories from individuals who benefited from the test, while discussing ongoing research to determine its effectiveness in improving cancer outcomes.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  19. 197

    BPC-157: What Are You Really Buying?

    Karen takes a look at BPC-157, the buzzy peptide touted for faster healing and joint relief, explaining what animal studies actually show, the lack of human clinical trials, and its regulatory reality.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  20. 196

    Getting to the Point: Microneedling Reviewed

    Karen demystifies the popular skincare treatment known as microneedling. She explores how this minimally invasive procedure stimulates collagen and elastin production to improve skin texture, reduce wrinkles, and help with scars and stretch marks. She compares professional treatments with at-home devices, explains the pros and cons of each, and provides detailed guidance on safe at-home use.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  21. 195

    Unpacking Your Eye Bags

    Karen tackles the puffy eye predicament that's turning well-rested people into walking advertisements for concealer. From the cruel reality of aging to your body's dramatic reaction to that late-night pizza binge, Karen breaks down the reasons your under-eyes are staging their own little rebellion.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  22. 194

    GLP-1 Meds & Hair Loss: Skinny and Bald Not the Look You're Going For?

    Karen tackles the surprising link between GLP-1 medication (like Ozempic and Wegovy) and hair loss. As more people turn to these drugs for diabetes and weight management, some are left wondering: is the price of shedding pounds also shedding your hair? Karen explores possible causes behind this side effect, including rapid weight loss, nutritional deficiencies, and hormonal changes, and shares science-backed strategies to help prevent or reduce hair thinning while on these medications.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  23. 193

    How to Keep Your Cool as the World Heats Up (RERUN)

    Karen shares potentially life-saving advice for staying safe in extreme heat as record-breaking temperatures sweep across the country. She explains how heat exhaustion and heat stroke develop, how to recognize early warning signs, and what to do if you or someone else is affected.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  24. 192

    Methylene Blue: What Is It Really?

    Karen unpacks the hype surrounding methylene blue, a vivid cobalt dye that's gained popularity as a trendy wellness supplement. From its historical use as a textile dye and medical treatment to modern claims about boosting brain power, energy, and longevity, Karen breaks down what the science actually says—and what it doesn’t. With potential risks ranging from drug interactions to serotonin toxicity, she urges listeners to think twice before adding this unregulated supplement to their daily routine.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  25. 191

    Face Taping: Karen's Mom is Loving This!

    Karen breaks down the growing trend of face taping as a non-invasive approach to reducing wrinkles and lifting sagging skin. She explains the difference between aesthetic taping for red carpet-ready lift and overnight wrinkle patches like Frownies that aim to retrain facial muscles. Karen walks listeners through product options, techniques, and safety tips—while sharing her own experiences (and her mom’s timeless advice) about fighting the dreaded “11s.”Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  26. 190

    Presto Chango: Hormone Precursors

    Karen breaks down the benefits of precursor hormones—specifically pregnenolone and DHEA—for those who struggle with traditional hormone replacement therapy. She explains how these naturally occurring compounds support the production of estrogen, progesterone, and testosterone, and how they may offer relief from symptoms like brain fog, fatigue, sleep disturbances, and low libido.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  27. 189

    Cancer in Young Adults: What in the World is Happening?

    Karen addresses the troubling rise in early-onset cancers among adults under 50, particularly women. Drawing on the latest research, she discusses contributing factors—from delayed screenings and family history to gut health, environmental exposures, and systemic inflammation. Karen also highlights how current healthcare gaps, lifestyle factors, and even prenatal influences may be playing a role in this growing health crisis.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  28. 188

    The Hormone Makeover with Donna White

    Karen welcomes Donna White, a leading expert in bioidentical hormone replacement therapy (BHRT) with over 30 years of experience. They discuss the myths and truths about hormone therapy, the critical role of proper testing and individualized treatment plans, and how BHRT can drastically improve quality of life for women in menopause and beyond. Donna shares her personal journey with hormonal imbalance, her mission to train providers across the country, and practical advice for finding a knowledgeable, well-trained BHRT provider.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  29. 187

    Hormones and High Notes

    Karen unpacks the surprising connection between hormones and the human voice—especially for singers. Drawing from her dual background in opera and medicine, she explains how hormonal shifts throughout the menstrual cycle can impact vocal quality, flexibility, and range.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  30. 186

    Scalp Cooling to Spare Your Hair During Chemotherapy

    Karen shares how a friend's breast cancer diagnosis became a powerful example of self-advocacy in action. From discovering she didn’t need chemotherapy after requesting additional testing, to researching scalp cooling treatments and skin protection during radiation, this story highlights how knowledge and persistence can lead to better care. Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  31. 185

    The Best Health Advocate is YOU!

    Karen shares a powerful listener story about self-advocacy in healthcare and how trusting your instincts can be lifesaving. After experiencing persistent symptoms that were initially dismissed by a doctor, this listener took charge of her health, sought a second opinion, and ultimately discovered a serious diagnosis.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  32. 184

    Menopause and HPV (Part 2 of 2)

    Karen continues her discussion on HPV, focusing on the types of cancers it can cause and the best prevention methods. She breaks down the staggering statistics on HPV-related cancers, explains why the virus can remain dormant for decades, and highlights the importance of screening and early detection.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  33. 183

    Menopause and HPV (Part 1 of 2)

    Karen unpacks the risks of HPV for women in their perimenopausal and menopausal years. She explains how the virus spreads, why it can re-emerge decades after initial exposure, and how hormonal and immune system changes impact its persistence.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  34. 182

    Iodine: This Element is Elemental!

    Karen explores the importance of iodine and how its deficiency can impact overall health. She discusses the essential role iodine plays in thyroid function, metabolism, and cognitive development, particularly in pregnant women. Karen explains why iodine deficiency is on the rise, how to test for it, and the best ways to ensure adequate intake through diet and supplements.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  35. 181

    Not Another UTI! Help on the Horizon

    Karen explores the potential of UTI vaccines as an alternative to antibiotics for treating recurrent urinary tract infections. She explains how UTIs develop, why traditional antibiotic treatments often fail, and how vaccines work to boost the body's immune response.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  36. 180

    Love Your Liver? Think Twice Before Starting Kava for Anxiety

    Karen examines the use of kava supplements, exploring their potential benefits for anxiety and their serious risks, including liver toxicity. She highlights key studies on kava's effectiveness, explains its traditional use, and warns of its interactions with medications. She also shares a list of alternative supplements that have been shown to help with anxiety and depression without the significant risks associated with kava. Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  37. 179

    2025 Resolutions: Karen Has One, Do You?

    Karen kicks off 2025 by examining the science behind New Year's resolutions. She explores why we make them, who is most likely to set goals for the new year, and the reasons resolutions often fail. She also shares practical tips for improving success rates, such as setting small, meaningful goals, using habit trackers, and practicing self-compassion after setbacks.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  38. 178

    The Great Undies Debate

    Karen settles the great debate: should you sleep with or without underwear? She explores the health benefits and potential drawbacks of both choices. From reducing the risk of infections to promoting vaginal health, she provides research-backed insights to help you make the best decision for your body.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  39. 177

    Baby, It's Cold Outside: What to Know About Cold Related Illness

    Karen discusses the dangers of cold-related illnesses and how to stay safe during the winter months. She explains the causes, symptoms, and prevention strategies for conditions such as hypothermia, frostbite, chillblains, and trench foot. Learn practical tips for dressing warmly, avoiding prolonged exposure to cold, and recognizing early warning signs of these conditions to prevent severe complications.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  40. 176

    A Vagina Day! Beating Bacterial Vaginosis

    Karen addresses bacterial vaginosis (BV), a common vaginal infection that affects many women. She explains its symptoms, causes, and risk factors, while offering practical solutions for both treatment and prevention. From prescription antibiotics to boric acid suppositories and probiotics, Karen shares a comprehensive approach to managing recurrent BV.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  41. 175

    How to Reset Distress to Peace and Joy

    Karen shares a collection of grounding techniques to help listeners manage stress, anxiety, and negative emotions.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  42. 174

    Sore Tongue or Cracked Lips? Might Be Iron Deficiency Anemia

    Karen sheds light on iron deficiency anemia, covering its causes, symptoms, and treatment options. She explains the stages of anemia development, common risk factors, and how to recognize signs like fatigue, pale skin, and brittle nails.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  43. 173

    HRT Pellets: A Pain in the Butt or a Perfect Fit?

    Karen discusses hormone pellet therapy, one form of bioidentical hormone replacement that is designed to produce consistent, long-term hormone levels. She outlines how these tiny pellets are inserted under the skin and can be used to minimize the symptoms of menopause and hormone imbalance—exploring the benefits, possible side effects, and risks associated with them. She also gives tips on what to expect with the treatment and suggestions for finding a trusted provider.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  44. 172

    Inositol – It Helps Mood & Metabolic Problems

    Karen takes on the topic of inositol supplements, particularly their benefits for managing metabolic and mood disorders. She explores the science behind inositol, a substance naturally found in the body, and how it can support insulin regulation and neurotransmitter balance.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  45. 171

    Magnesium Mix-up: So Many Choices! (RERUN)

    Karen answers the question: "What type of magnesium should I take if I decide to take a supplement?" She explains magnesium's essential role in health, touching on its benefits for brain, heart, and muscle function, and highlights the widespread issue of magnesium deficiency, often due to processed food diets.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  46. 170

    Karen Tells All About How to Improve That Saggy, Wrinkled Face

    Karen covers the topic of estrogen loss during perimenopause and its effects on skin health, particularly facial skin. She explores how declining estrogen levels lead to reduced skin elasticity, collagen loss, and increased dryness, and discusses the benefits of using topical estrogen creams to counteract these effects. She also reviews the history of estrogen in skincare, recent studies on its effectiveness, and shares her own experience with adding estrogen cream to her facial care regimen.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  47. 169

    Blood Test for Multiple Cancers: Yup, It Exists!

    Karen explores the Galleri test, a multi-cancer early detection (MCED) blood test that can identify over 50 types of cancer. She explains how the test works, its potential benefits, and the risks associated with its use. She also shares personal stories from individuals who benefited from the test, while discussing ongoing research to determine its effectiveness in improving cancer outcomes.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  48. 168

    There's No Hocus-Pocus to Get Focus

    You have a limited offer you can use now, that gets you up to 48% off your first subscription or 20% off one time purchases with code ITCHY20 at checkout. You can claim it at: https://magicmind.com/itchyKaren explores the topic of improving focus and concentration, sharing research-backed methods to help listeners sharpen their mental clarity. From brain training games like Sudoku and crossword puzzles to the benefits of regular exercise and proper sleep, Karen provides practical tips for enhancing cognitive function.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  49. 167

    Debunking TikTok Trends: Garlic Cloves Up the Nose?

    Karen addresses the rise of medical misinformation on TikTok. She highlights the dangers of following non-factual advice from non-medical influencers, explaining the importance of consulting reliable sources and medical professionals for health advice. She also provides tips on how to identify and avoid false health claims on social media. Learn how to navigate the murky waters of TikTok health trends and protect your well-being.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

  50. 166

    The Bite IS Worse Than the Buzz: Mosquito Borne Diseases (Part 2)

    In part two of our series on those pesky mosquitos, Karen dives into practical measures to prevent mosquito bites and protect against mosquito-borne diseases. She explores effective repellents, proper application methods, and household tips to minimize mosquito presence. Tune in to find out how Victoria's Secret could play a role in preventing bug bites this summer.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

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ABOUT THIS SHOW

Nurse practitioner Karen Nickell discusses the realities of menopause and the female midlife in a way that is both informative and fun.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.

HOSTED BY

Karen Nickell

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