PODCAST · health
Longevity Metrics
by Bill Brandenburg, MD
Longevity is the ultimate expression of human health. This podcast is for those rare individuals that seek to optimize their long term health and performance. No false promises, empty claims, or sales funnels. Just evidenced based education and research about the science of aging, how to optimize longevity, diagnostics for measuring health (longevity metrics), lifestyle optimization, environment optimization, disease prevention, prediction, and management. If you want to move the needle on your longevity, this is the place! If you want the latest research on longevity, here we go!
Episodes
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Carotid Artery Ultrasound and Longevity
Carotid Artery Ultrasound and Longevity The opposite of longevity is death. If longevity is what we seek we must obsess about death, and those things that increase the risk of us dying. #1 Killer – Cardiovascular Disease Cardiovascular disease is the biggest killer on the block claiming the lives...
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Visual Acuity and Longevity
Visual Accuity and Longevity Happy Halloween everybody! Hope everybody is dressing up, My kids are being Spiderman, Boba Fett, and a black cat. I am going out as Darth Vader. If you are new to parenting, you are probably also realizing that candy is an alcohol equivalent for children and they...
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Longevity Metrics
Health and longevity are measurable, quantifiable, and malleable. The first step toward health optimization is awareness. Awareness starts with measuring. Because: “What gets measured gets managed” - Said by many, made famous by Peter Drucker (known for modern management theory) - This idea is…
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Your Longevity Report Card
Your Longevity Report Card Today on Full Scope, I want to talk to you about Longetrics comprehensive, longevity focused, health screening, Your Longevity Report Card. Full disclosure, this service is how I make a living. As such, all of the recommendations and ideas in this podcast contain an...
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Life Expectancy in the United States - Declining for Over a Decade
There is a buzz about longevity. Many people feel that we are on the brink of a lifespan revolution. There is talk of making living to 100 the new norm. But the reality is just the opposite. So, I thought I should. The truth: Life expectancy is actually declining. Since its peak in 2014, the...
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Hype and Snake Oil in Longevity Medicine
The hype around longevity is huge in 2025. Money is pouring into the space. Longevity Start-ups are launching. Big claims are everywhere. But is all the hype justified? What can longevity medicine actually deliver now? Let's start with some quotes: Listen carefully. These come from leaders in the...
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Longevity Philosophy
Longevity Philosophy 5 Big Ideas That Will Deliver More Years NOW The longevity space is filled with empty claims! For example: - This supplement will extend your life (C15, spermidine, D3, fish oil, etc.) Truth: No supplement has ever been shown to extend human life in all comers (outside of a...
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DEXA Scan
Today we are going over the basics of DEXA. This will help patients understand the test and what is being measured. It will also help clinical providers understand this test better. Let's dive in! The Basics DEXA stands for Dual Energy X-Ray Absorptiometry - Xray machine used for analyzing body...
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Muscle, Biological Gold, Part 2
Muscle is your bodies bank account. It is the currency of life. It is biological gold. Quote: “I lift weights, and I lift weights for 1 reason, to be strong” – Arnold Schwarzenegger Deadlifts Deadlift: Lifting a weight from the floor to hip level. We use this movement anytime we pick something up...
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Muscle, Biological Gold, Part 1
Quote: “In movement, there is life” – Aristotle “Genius starts with the abs Max” – The Grinch Muscle is your bodies bank account. It is the currency of life. It is biological gold. Why Do People Need Nursing Homes? As a hospitalist I frequently have to place people in nursing homes . I estimate...
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VO2 Max, Part 2
Quote: “The greatest wealth is health” - Virgil, Roman poet < 2000 years ago Higher VO2 Max = Much Lower Risk of Dying…….Get off your ass! Let's illustrate this point: ICU Patient 68 year old man with diabetes type 2 presenting with weakness and shortness of breath found to have sepsis due to...
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VO2 Max, Part 1
Title: VO2 Max, Part 1 This is just the 101 course: Quote: “If you don’t make time for exercise, you will probably have to make time for illness” - Robin Sharma, Attorney, Writer, Consultant What is VO2 Max Perhaps the most important metric for longevity and health in 2024 V=Volume (actually…
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Health Report Cards
Title: Health Report Cards Quote: “what gets measured gets managed” - unknown source When you measure something you become aware of it and can objectively manage it. Potential Pitfalls: The right things must be measured. Measurement must be accurate. What is a Report Card: - an evaluation of...
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Longevity Conferences (ARDD and Dublin Longevity)
Title: Longevity Conferences (ARDD and Dublin Longevity) Quote: “Its not what you know but who you know” Said by many across multiple cultures Today we review: The Aging Research and Drug Discovery Conference in Copenhagen, Denmark The Dublin Longevity Summit in Dublin, Ireland 3 Plugs - keep...
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The Longevity Physician
Quote: “The best physician is also a philosopher” – Galen (Claudius Galenus) Reflection is key! What can I do better and why am I doing it in the first place? Harness failures as the great teachers that they are and constantly improve. Why this person is important: Roman and Greek Physician,...
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Why Longevity
Quote: “Death gives meaning to our lives. It gives importance and value to time. Time would become meaningless if there were too much of it” - Ray Kurzweil Too much time….. Why this person is important: Computer scientist, inventor, and futurist (one of the greatest of the modern era) What is...
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How You Will Die
Death is coming for you, me, and all of this. If you seek Longevity, stop avoiding this, assess your risks, and make a plan. Blog post about this podcast available at: https://www.wondermedicine.com/wonder-medicine-blog How to assess death - What are my current medical problems, risks, and...
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4 Amazing Ways Ketamine Will Change Your Brain
Live Better, Longer A Longevity Physicians Secrets to Health and Fulfillment Available for free at: wondermedicine.com See full written episode description on our blog available at: https://www.wondermedicine.com/wonder-medicine-blog 4 Amazing Ways Ketamine Will Change Your Brain Ketamine is an...
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Longevity and Performance Program at Wonder Medicine
Executive Summary The Longevity and Performance Program at Wonder Medicine is a physician directed-proactive healthcare program for high performing individuals. Its principle aims are health optimization, disease prediction and prevention, exceptional performance, emotional wellness, and…
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4 Longevity Tips to make this Holiday Season Exceptional
Holiday Season October 31 – January 2nd Halloween to New Years - Tough time of year - Loved ones, memories of past loved ones, relationships gone bad, events, obligations, good memories, bad memories, and even trauma. - Can be the best time of the year or a time of pain. - Take care of yourself,...
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Lifestyle Medicine with Benjamin Franklin and Wonder Medicine
Benjamin Franklin: “Search others for their virtues, thy self for thy vices” - Poor Richards Almanac The best way to maximize longevity in 2023 is not a drug, supplement, or other high tech therapeutic; its Lifestyle medicine. Wonder Medicine specializes in the translation of longevity…
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Dia de Los Muertos and Longevity
Dia de Los Muertos and Longevity The day of the Dead. What can the dead and this Mexican cultural holiday teach us about longevity? Is there more to the story than candy, spooky witches, monsters, tricks, and treats. Let's find out What is day of the Dead? - A holiday most often celebrated on Nov...
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The 6 BIG Benefits of Longevity
The 6 BIG Benefits of Longevity Be a victim or conquer longevity. You must choose! Longevity - Longevity Definition: Long existence or service - Human longevity relates to both existence (remaining alive) and service (remaining useful). - I strive for nothing less than long existence and long...
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Blue Zones
Live to 100: Secrets of the Blue Zones - 2023 Netflix documentary, 4 episodes - Based on the 2008 book: “The Blue Zones: Lessons for Living Longer from People Who’ve Lived the Longest.” - By Dan Buettner, Journalist, National Geographic Explorer, New York Times Best Seller What is a Blue Zone -...
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Stop Avoiding the (Your) Thing
We all have weaknesses. These weaknesses will eventually limit your life and longevity tremendously. Train these weaknesses out and become the best version of yourself. See full notes at: https://www.wondermedicine.com/wonder-medicine-blog
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Three Things to Improve Your Longevity Today
Blog post about this podcast available at: https://www.wondermedicine.com/wonder-medicine-blog Three Things to improve your longevity today. 1. Exercise - Stop pretending to care about longevity or health if you are not exercising - Bodies in motion stay in motion, bodies that stop, soon stop...
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The Wonder Medicine and Bill Brandenburg Story in 2023
Overview - new 10-to-20-minute podcast every Monday - the science, philosophies, and actional information around health, longevity, and performance - meant to help listeners become the highest performing individual possible - Increase your lifespan, healthspan, and view your life through the full...
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61. Creatine
Summary Phosphocreatine is a molecule that can recharge ADP into ATP. This provides energy to skeletal muscle and the brain. Dietary and supplemental creatine can raise the bodies stores of phosphocreatine, providing additional energy. In this podcast, we discuss creatine, what is is, how it…
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Metabolic Syndrome
Summary Metabolic syndrome is a medical condition characterized by unhealthy and markedly deranged metabolism. Over 50% of United States adults have metabolic syndrome and another 40% are at risk of developing it (90% of US adults!). Metabolic syndrome is the great killer of our time, a global...
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Comfort Care, Hospice, Code Status, and Goals of Care
Summary What is your plan for medical care as you get older? Most people don’t know. While 87% of people say they want to die at home, just under half of people do. In this episode we discuss goals of care, comfort care, palliative care, hospice, code status and more. Morbidity and Mortality...
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Interview with Sycamore
Sycamore is a physician staffing and independent locums company that encourages physicians to run their career like a business. Price transparency, low fees, direct contracts, and aligned incentives set Sycamore Health apart from other physician staffing companies. In this interview, I discuss...
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Alcohol Withdrawal, Part 2
Alcohol Withdrawal, Part 2 Summary Drinking alcohol (specifically ethanol) on a regular basis leads to alcohol dependence. When alcohol dependent persons stop drinking, they experience withdrawal. Withdrawal from alcohol is very dangerous and should be managed aggressively in order to prevent…
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Alcohol Withdrawal, Part 1
Summary Drinking alcohol (specifically ethanol) on a regular basis leads to alcohol dependence. When alcohol dependent persons stop drinking, they experience withdrawal. Withdrawal from alcohol is very dangerous and should be managed aggressively in order to prevent long term complications and...
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Policy not Politics Interview
This is a conversation I had with Justin Cotton, host of the Policy not Politics podcast. It does not contain any medical knowledge. But it is a thought provoking conversations about my opinions regarding healthcare policy. Please enjoy. This will be the final episode of Full Scope season 2. I am...
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Sleep, Part 3 (How to Get Better Sleep)
Summary Sleep is the most important thing a person can do for themself. Getting 8 hours of quality sleep equals better cognition (thinking), better body function, less disease, and a longer lifespan. Morbidity and Mortality At least 20% of automobile accidents have been linked to sleep…
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53. Sleep, Part 2
Summary Sleep is the most important thing a person can do for themself. Getting 8 hours of quality sleep equals better cognition, better body function, less disease, and a longer lifespan. Morbidity and Mortality Atleast 20% of automobile accidents have been linked to sleep deprivation. Teenagers...
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52. Sleep, Part 1
Summary Sleep is the most important thing a person can do for themself. Getting 8 hours of quality sleep equals better cognition (thinking), better body function, less disease, and a longer lifespan. Morbidity and Mortality At least 20% of automobile accidents have been linked to sleep…
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51. Hospitals 2.0
Summary Acute care in the United States is considered to be among the best in the world. But do not be fooled. Healthcare is widely considered the third leading cause of death in the US. Additionally, we have considerable room for improvement in the care of our acutely sick patients. This podcast...
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Part 3, Genetic Diversity and the Extinction of the Human Microbiome
Summary Diversity in ecology and genetics appears to be a very good thing. The human species has a genetic pool (all the gene variants from all the humans alive) that is diverse and protective for our species. Human bodies and all other multi-cellular organisms also host diverse arrays of...
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Part 2, Genetic Diversity and the Extinction of the Human Microbiome
Summary Diversity in ecology and genetics appears to be a very good thing. The human species has a genetic pool (all the gene variants from all the humans alive) that is diverse and protective for our species. Human bodies and all other multi-cellular organisms also host diverse arrays of...
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48. Crisis Standards of Care and How Front Line Healthcare Workers Have Lost Complete Control of Healthcare
Summary Idaho entered a state wide crisis mode on Sept 16, 2021. Alaska has since followed. Many other state are also being hit hard. In this podcast, I discuss crisis care, leadership, and how front line healthcare workers have lost complete control of the healthcare industry. Morbidity and...
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47. Genetic Diversity and the Extinction of the Human Microbiome, Part 1
Summary Diversity in ecology and genetics appears to be a very good thing. The human species has a genetic pool (all the genes variants from all the humans alive) that is diverse and protective for our species. Human bodies and all other multi-cellular organisms host diverse arrays of...
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46. Autophagy
Summary We have been taught to not skip meals, make carbohydrates the most abundant macronutrient we consume, and to snack throughout the day. Sadly, this all appears to be wrong. Fasting exists in many forms and growing evidence suggests it is essential to health. We are all spending way too…
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Part 3, Human Destruction of Earth and Its Effect on Our Health
Summary Planet earth is being destabilized as a result of human activity. Over half of the habitable land on earth is now used for human agriculture, 40% of our forests have been cut down, and humans now move more rock and sediment than any natural process. If we do not act quickly, it is likely...
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Human Destruction of Earth and Its Effect on Our Health, Part 2
Summary Planet earth is being destabilized as a result of human activity. Over half of the habitable land on earth is now used for human agriculture, 40% of our forests have been cut down, and humans now move more rock and sediment than any natural process. If we do not act quickly, it is likely...
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43. Human Destruction of Earth and Its Effect on Our Health, Part 1
Summary Planet earth is being destabilized as a result of human activity. Over half of the habitable land on earth is now used for human agriculture, 40% of our forests have been cut down, and humans now move more rock and sediment than any natural process. If we do not change our behavior…
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Heat Stroke
Summary Exposure to warm environments can cause a number of heat-related illnesses including muscle cramps, heat rash, edema, syncope, heat exhaustion, and heat stroke. All of these issues are preventable. Early recognition of heat stroke is paramount for improving survival. Cool patients with…
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Radon
Summary Radon is a radioactive element that accumulates in homes and buildings. It is the second leading cause of lung cancer worldwide. All homes should be tested for radon, and if above actions levels (US - 4 pCi/L), a radon mitigations strategy (getting rid of the radon) should be utilized....
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Yellow Fever, Part 2
Summary Yellow Fever is a viral tropical disease. It is most prevalent in equatorial Africa (90%) and South America (10%). No specific treatments exist but it can be prevented with a highly affective vaccine. The disease is spread via mosquito vectors (arbovirus). Yellow refers to the jaundice…
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Yellow Fever, Part 1
Summary Yellow Fever is a viral tropical disease. It is most prevalent in equatorial Africa (90%) and South America (10%). No specific treatments exist but it can be prevented with a highly affective vaccine. The disease is spread via mosquito vectors (arbovirus). Yellow refers to the jaundice…
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ABOUT THIS SHOW
Longevity is the ultimate expression of human health. This podcast is for those rare individuals that seek to optimize their long term health and performance. No false promises, empty claims, or sales funnels. Just evidenced based education and research about the science of aging, how to optimize longevity, diagnostics for measuring health (longevity metrics), lifestyle optimization, environment optimization, disease prevention, prediction, and management. If you want to move the needle on your longevity, this is the place! If you want the latest research on longevity, here we go!
HOSTED BY
Bill Brandenburg, MD
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