Metabolic Mind

For decades, nutrition advice has centered on a single idea: that there’s one “right” way to eat for everyone. The standard low-fat, Mediterranean-style diet approach has shaped how we think about health. But it’s missing a critical piece.Here, Dr. Bret Scher breaks down the limitations of universal dietary recommendations and why relying on observational nutrition research may not provide clear answers for individual health.You’ll learn:Why “evidence-based” nutrition isn’t always as definitive as it seemsThe difference between observational studies and causal evidenceWhy metabolic health markers like insulin, triglycerides, and body composition matter more than just weight or cholesterolHow different people respond differently to the same dietWhen low-carb and ketogenic diets may offer powerful benefitsThis discussion challenges the idea of a single “best” diet and instead explores a more personalized approach, one that considers your metabolism, preferences, and long-term sustainability.As the field evolves, the future of nutrition may lie in moving beyond rigid guidelines and toward individualized care that actually works in the real world.👉 Explore what a well-formulated ketogenic diet looks like and how it may support metabolic health on our blog: Understanding the Well-Formulated Ketogenic Diet.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicineExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can ketosis trigger insomnia or even mania? Do you need supplements like L-carnitine to support ketone production? Is whey protein helping or hurting your metabolic health? And how do you maintain or gain weight on a ketogenic diet without losing ketosis?Harvard-trained psychiatrist Dr. Georgia Ede and cardiologist Dr. Bret Scher tackle your biggest questions in this Metabolic Mailbag episode, breaking down the science behind ketogenic metabolic therapy, including:Why some people struggle transitioning into ketosisThe role of electrolytes, protein, and meal timingBrain insulin resistance and mental healthCarnitine deficiency and ketone productionWeight loss vs. weight maintenance on a ketogenic dietProtein powders, dairy, and whole-food nutritionPractical ketogenic diet strategies for everyday lifeThis episode also explores an important theme in metabolic psychiatry: why metabolic health markers often tell us more than standard blood sugar testing alone, and how ketogenic interventions may support brain function even in people without obvious metabolic disease.Whether you're exploring ketogenic therapy for mental health, improving metabolic health, or simply trying to make keto sustainable long term, this episode is packed with practical insights and nuanced discussion.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicine #Q&AExpert Featured:Dr. Bret Scherhttps://x.com/bschermdDr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemd/https://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enExperts Mentioned:Dr. Guido Frankhttps://www.instagram.com/ucsdfranklab/linkedin.com/in/guido-k-w-frank-b7b42172https://profiles.ucsd.edu/guido.frankResources Mentioned:https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1749406/fullFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

For decades, LDL cholesterol has been the go-to metric for assessing heart disease risk. But growing research suggests there's a better predictor: ApoB. But is it a predictor in itself, or is it a marker of something even more important?Apolipoprotein B (ApoB) is a protein found on all potentially harmful lipoprotein particles, like LDL, VLDL, and remnants. Because each particle carries one ApoB, it offers a direct count of the total number of atherogenic particles, something LDL cholesterol can’t do.In this video, Dr. Bret Scher breaks down the key differences between LDL and ApoB, how metabolic health influences both, and why understanding the full picture is critical for preventing heart disease.📌 What you’ll learn:Why ApoB is more predictive than LDL in metabolically unhealthy individualsThe role of particle number vs. cholesterol contentWhat LDL and ApoB each reveal — and where they fall shortHow metabolic dysfunction drives up ApoB and cardiovascular riskWhy improving insulin sensitivity and inflammation matters more than chasing numbersWhether you're managing your own heart health or guiding others, this video will help you interpret labs more clearly so you can focus on what really matters.👉 Subscribe to Metabolic Mind to stay up-to-date on the latest in metabolic health, ketogenic therapy, and mental wellbeing: https://www.youtube.com/@metabolicmind.#MetabolicMind #KetogenicTherapy #HeartHealth🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdhttps://www.linkedin.com/in/bret-scher-08baaa102/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Starting a ketogenic diet, reaching ketosis, and setting the right keto macros can feel overwhelming at first, but the fundamentals are simpler than they seem. In this video, Dr. Bret Scher breaks down how to start a keto diet step by step, including how to lower carbs, balance protein, and use fat as your primary fuel source.Whether your goal is weight loss, metabolic health, or therapeutic ketosis, this guide walks through the key principles to help you get started safely and effectively.This video covers:How to reduce carbohydrates to reach ketosisHow much protein you need on a ketogenic dietHow fat supports energy and satiety on ketoWhat causes “keto flu” and how to minimize symptomsWhy hydration and electrolytes are essentialHow to test ketones and track progressYou’ll also learn how different dietary approaches, such as Mediterranean, vegetarian, and others, can still support ketosis when carbohydrates are low enough.Importantly, Dr. Scher notes that if you’re using a ketogenic diet for a medical or mental health condition, it’s important to work with a qualified healthcare provider. Dietary changes can affect medications and symptoms, making it crucial to have your healthcare team on board.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicineExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:https://www.metabolicmind.org/thinksmart/https://www.metabolicmind.org/resources/topics/bipolar/https://www.metabolicmind.org/resources/topics/schizophrenia/https://www.metabolicmind.org/resources/topics/keto-for-depression/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

As interest grows in alternative approaches to post-traumatic stress disorder (PTSD), like ibogaine and psilocybin-assisted therapy, researchers are also exploring how metabolic interventions may target the underlying biology of psychiatric conditions.Dr. Bret Scher speaks with Nicole Laurent, a licensed therapist and researcher, about a published case report exploring ketogenic metabolic therapy in treatment-resistant PTSD.Together, they break down some of the biology behind PTSD, including brain hypometabolism, oxidative stress, and neurotransmitter imbalances, and how ketogenic therapy may help address these underlying mechanisms.The conversation also explores a powerful real-world case: a woman with nearly two decades of persistent PTSD symptoms who experienced profound improvements after implementing a medically supervised ketogenic approach.In this conversation, you’ll also learn:Why metabolism may play a central role in psychiatric conditionsHow ketogenic therapy may support brain energy and neurotransmitter balanceThe importance of clinical supervision, especially when medications are involvedWhy individualized care and self-advocacy matter in emerging treatmentsWhile case reports don’t establish causation, they can highlight new directions for research and clinical care, especially for individuals who haven’t found relief with standard approaches.As research evolves, metabolic psychiatry is opening new conversations about how we understand and treat mental health conditions. If you or someone you love is living with PTSD, this discussion may offer a new perspective to explore with a qualified healthcare provider.Learn more about ketogenic therapy as an adjunct treatment for PTSD on our blog: Hope for PTSD: The Potential of Ketogenic Metabolic Therapies.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #PTSDExpert Featured:Nicole Laurent, LMHChttps://www.metabolicmind.org/team/nicole-laurent-lmhc/https://mentalhealthketo.com/nicole-laurent-lmhc-about-me/Chris Palmer, MDhttps://www.chrispalmermd.com/https://www.metabolicmind.org/team/chris-palmer-md/https://www.instagram.com/chrispalmermd/Resources Mentioned:PTSD Case Report: https://pubmed.ncbi.nlm.nih.gov/41783812/Robin Engelhardt Case report: https://www.researchgate.net/publication/400616091_Ketogenic_Therapy_as_a_Novel_Treatment_Approach_for_PTSD_An_Integrative_Review_and_ModelPalmer Case report: https://pmc.ncbi.nlm.nih.gov/articles/PMC12089804/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can a ketogenic diet affect your thyroid? What about bone health, uric acid, cannabis use, or ketone supplements?In this Metabolic Mailbag episode, Dr. Bret Scher and Dr. Georgia Ede answer your most pressing questions about ketogenic therapy and how it interacts with real-world health concerns.From thyroid function to mental health, this conversation highlights how nuanced and individualized metabolic therapies can be.You’ll learn:How ketogenic diets influence thyroid hormones, and why lower T3 doesn’t necessarily mean hypothyroidismWhen to monitor thyroid function more closely, especially with pre-existing conditions or medications like lithiumWhat the evidence says about protein intake, uric acid, and bone healthWhy temporary changes during the adaptation phase (like uric acid fluctuations) may not reflect long-term outcomesHow cannabis use may affect appetite, cravings, and adherence to a ketogenic dietWhether exogenous ketones and MCT oil provide the same benefits as nutritional ketosisDr. Ede also shares a key principle: context matters. Lab values, symptoms, and individual biology all need to be considered together, especially when using ketogenic therapy for mental health or metabolic conditions.The key takeaway: ketogenic therapy is not one-size-fits-all. It’s a dynamic, personalized approach that often requires thoughtful monitoring, adjustments, and collaboration with a knowledgeable clinician.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret Scherhttps://x.com/bschermd?ref_src=twsrc^google|twcamp^serp|twgr^authorhttps://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enExperts Mentioned:Dr. Jeff VolekWebsite: https://lowcarb.osu.edu/https://www.linkedin.com/in/jeff-volek-b3944092Dr. Stephan D. Phinneyhttps://www.linkedin.com/in/stephen-phinney-631467/Dr. Dom D’Agastinohttps://secure.instagram.com/dominic.dagostino.kt/Resources Mentioned:National Osteoporosis Foundation study on protein and skeletal health - https://pubmed.ncbi.nlm.nih.gov/28404575/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can something as simple as coconut oil support brain health in dementia?In this video, Dr. Bret Scher explores an emerging area of research focused on brain energy metabolism and how ketones may play a role in supporting cognitive function in conditions like Alzheimer’s disease and mild cognitive impairment.As the brain’s ability to use glucose declines in Alzheimer’s, researchers have begun investigating whether ketones can help fill that energy gap.In this video, you’ll learn:Why the brain may experience an energy deficit in Alzheimer’s diseaseHow ketones provide an “alternative” fuel for the brainThe role of coconut oil and MCTs in raising ketone levelsInsights from Dr. Mary Newport’s early observations and case reportsResearch from Dr. Stephen Cunnane on brain energy metabolismWhat current studies suggest about ketogenic therapies and cognitive functionCommon concerns about saturated fat and coconut oilDr. Scher also discusses the limitations of the current evidence. While early findings are promising, much of the research is still in its early stages, and more rigorous clinical trials are needed.At the same time, for individuals and families facing cognitive decline, low-risk lifestyle approaches like ketogenic strategies may be worth exploring under medical guidance.💡 To learn more about metabolic approaches to brain and mental health, visit metabolicmind.org🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #AlzheimersDisease #FoodAsMedicineExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:https://www.metabolicmind.org/resources/news-views/podcasts/metabolic-mind-podcast/hundreds-report-dementia-improvement-with-ketones-dr-mary-newports-report/https://www.metabolicmind.org/resources/news-views/podcasts/metabolic-mind-podcast/keto-and-mct-for-alzheimers-one-doctors-family-journey/https://www.metabolicmind.org/resources/news-views/podcasts/metabolic-mind-podcast/how-ketones-support-the-aging-brain-psychiatric-meds-disrupt-brain-energy-dr-stephen-cunnane/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Exogenous ketones have exploded in popularity, with claims ranging from better brain function to improved performance and weight loss. But what does the science actually say?In this in-depth conversation, Dr. Bret Scher sits down with leading ketone researcher Dr. Dominic D'Agostino to break down the reality behind exogenous ketones—what they are, how they work, and where they may (or may not) fit into your health strategy.They explore the key differences between:Endogenous ketones (produced by your body through diet or fasting)Exogenous ketones (supplements you consume)And why that distinction matters for both metabolic and brain health.This conversation covers:The different types of exogenous ketones (salts, esters, those derived from MCTs)Potential benefits for brain energy, seizures, and metabolic healthSafety considerations and why formulation mattersWhy exogenous ketones are best viewed as a tool, not a replacement for a ketogenic dietThe concept of a “sweet spot” for ketone levels in different conditionsOne of the biggest takeaways: context is everything. Exogenous ketones may offer the most benefit when used to support a well-formulated metabolic approach, rather than as a standalone shortcut.Dr. D’Agostino also shares insights from decades of research, including work with the Department of Defense, and discusses where the science is headed, especially in areas like neurological and psychiatric conditions.👉 Learn more about the growing body of research on ketogenic therapy and mental health on our clinical trials page: metabolicmind.org/resources/science/clinical-trials/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #ExogenousKetonesExpert Featured:Dr. Dom D’Agostinohttps://health.usf.edu/medicine/mpp/faculty/ddagostihttps://www.instagram.com/dominic.dagostino.kt?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==https://ketonutrition.org/Resources Mentioned:Papershttps://pubmed.ncbi.nlm.nih.gov/23552496/Additional resourceshttps://ketonutrition.org/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field, including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher, with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

GLP-1 medications like semaglutide have been widely discussed as breakthrough treatments for weight loss and metabolic health. But a large new study published in The Lancet Psychiatry is shifting the conversation toward something deeper: the connection between metabolic health and mental health.In this video, Dr. Bret Scher breaks down what the research actually shows, and just as importantly, what it doesn’t.The study analyzed health records from over 95,000 individuals with type 2 diabetes and depression or anxiety. Those taking GLP-1 medications showed a lower risk of severe psychiatric outcomes, including hospitalization and self-harm, compared to other diabetes treatments.But here’s the nuance:This wasn’t an intervention trial, and it didn’t show that GLP-1s treat depression or lead to remission. Instead, it showed less worsening of mental health over time.This video explores:What “less worsening” really means in mental health researchWhy metabolic health and brain health are closely connectedThe limitations of large observational studiesHow GLP-1s might fit into a broader metabolic approach to mental healthThe emerging role of ketogenic therapy and other metabolic interventions👉 To learn more about responsible use and clinical considerations for GLP-1 medications, explore the Coalition for Metabolic Health’s policy brief on GLP-1s.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #CoalitionForMetabolicHealth #KetogenicTherapyExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Coalition for Metabolic Health’s policy brief on GLP-1sFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

GLP-1 receptor agonists like semaglutide are often described as “game changers” for weight loss and cardiovascular health, and in many ways, the data support that claim. Clinical trials suggest meaningful reductions in major cardiovascular events, offering hope for individuals struggling with metabolic disease.But there’s an important nuance that deserves more attention: what happens when these medications are stopped?In this conversation, Dr. Bret Scher explores emerging real-world data showing that the benefits of GLP-1s, particularly for cardiovascular risk, appear to depend on continued use. For many individuals, stopping the medication leads to a reversal of progress, raising important questions about long-term strategy, sustainability, and what true metabolic healing looks like.Are we managing symptoms, or addressing root causes?What role should medications play in long-term care?How can we use powerful tools like GLP-1s to support, rather than replace, sustainable metabolic change?For some individuals, long-term use may be appropriate and beneficial. But we need to broaden the conversation toward approaches that aim to improve underlying metabolic health, support lasting behavior change, and ultimately reduce reliance on lifelong interventions when possible.If you’re exploring GLP-1s or are currently taking one, consider speaking with your healthcare provider about how to pair your treatment with sustainable lifestyle strategies such as nutrition, physical activity, and metabolic support, to help maintain progress over time.👉 How do GLP-1 medications impact mental health? Learn more on our blog:Ozempic, Wegovy, and Mental Health: Are GLP-1 Drugs Linked to Suicidal Thoughts?🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #GLP1 #FoodAsMedicineExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Glucagon-like peptide 1 receptor agonist discontinuation and risks of major adverse cardiovascular events in adults with type 2 diabetes: target trial emulationhttps://bmjmedicine.bmj.com/content/5/1/e002150Coalition for Metabolic Health: GLP-1 Policy Briefhttps://coalitionformetabolichealth.org/resources/glp-1-medications-and-metabolic-health/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

We’re seeing increasingly compelling results from ketogenic therapy in serious mental illness, including schizophrenia, bipolar disorder, and major depression. But what happens when a potential concern emerges along the way?In this conversation, Dr. Bret Scher sits down with psychiatrist Dr. Lori Calabrese to walk through a real patient case that highlights both the promise and the complexity of metabolic treatment.A young woman with longstanding schizophrenia experienced dramatic improvements in her mental health, metabolic markers, and quality of life after starting a ketogenic intervention. But alongside these gains, her LDL cholesterol rose significantly, raising important clinical questions.Rather than defaulting to extremes, either stopping the therapy or ignoring the lab values, Dr. Calabrese takes a thoughtful, patient-centered approach:Investigating deeper cardiovascular risk markersExploring potential underlying causes, including familial hypercholesterolemiaCollaborating across specialties, including cardiologyPrioritizing both psychiatric recovery and long-term healthThis case illustrates a critical principle in metabolic psychiatry: context matters. Lab values don’t exist in isolation, and neither do patients.It also highlights a broader shift in medicine where clinicians are increasingly called to step beyond traditional silos and consider the full metabolic picture when treating brain-based conditions.At Metabolic Mind, we believe these nuanced conversations are essential. The goal isn’t to ignore risk or to abandon effective therapies, but to better understand both so individuals can make informed decisions alongside their care teams.You can learn more about this conversation in the documentary The Cholesterol Code. The film shares firsthand accounts from individuals whose lives improved with ketogenic therapy, even as their LDL levels rose dramatically. It also follows how they worked with their care teams to better understand their cardiovascular risk and what that approach could mean in your own situation.🎬 The Cholesterol Code is now streaming on Amazon: https://www.amazon.com/gp/video/detail/B0GS8ZFCYN/#MetabolicMind #KetogenicTherapy #FoodAsMedicineExpert Featured:Lori Calabresehttps://www.loricalabresemd.com/https://www.metabolicmind.org/team/lori-calabrese-md/https://www.linkedin.com/in/loricalabresemdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

What do you do when keto is genuinely changing your life, but your LDL goes up?That's exactly the question Dr. Bret Scher sits down to answer in this conversation with podcast producer Erica Gerard.Erica started ketogenic therapy for two reasons: to support her taper off long-term antidepressants, and to address symptoms of complex PTSD. Six months in, the results were remarkable. A smoother taper, less anxiety, fewer flashbacks, and a greater sense of calm than she'd ever experienced.Then she got her labs back. Her LDL had jumped from 94 to 150.In this episode, Dr. Scher walks through one way to think about a rising LDL in the context of ketogenic therapy, and why the answer is almost never "stop doing what's working."You'll hear:Why total cholesterol is the least useful number to focus onWhy LDL is not the disease, vascular disease isWhat advanced imaging options exist for a more complete picture of heart healthWhy an initial LDL rise on keto may resolve on its own within a yearHow to have a productive conversation with your doctor about thisThis conversation sits at the heart of a bigger question, one that The Cholesterol Code documentary explores in depth.Featuring individuals whose lives were transformed by ketogenic therapy, only to see their LDL rise dramatically, the film asks an important question. Is abandoning a life-changing intervention really the right answer based on one biomarker alone? Is there a better way to assess heart health?🎬 The Cholesterol Code is now streaming on Amazon: https://www.amazon.com/gp/video/detail/B0GS8ZFCYN/AFTER YOU WATCH — Do this to help this film make a bigger impact 👇Leaving an honest review on Amazon can make a real difference. Reviews help this film qualify as an Amazon Prime listing, putting it in front of a much larger audience who might never have found it otherwise.You can also help this film reach more people by sending it directly to friends, family, and colleagues who you think could benefit from watching it. Start now by tagging a friend in the comments!Expert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

How do the latest Dietary Guidelines for Americans (DGA) and the American Heart Association (AHA) recommendations compare, and why do they differ?In this video, Dr. Bret Scher breaks down where these two major nutrition guidelines align, where they diverge, and what that means for your health. At the center of the conversation is a key question: should health be defined by a single lab marker, or by a broader view of metabolic function?In this video, you’ll learn:Why LDL cholesterol is only one piece of cardiovascular riskWhy the two guidelines differ on saturated fat, red meat, and full-fat dairyThe role of markers like fasting insulin, triglycerides, HDL, and body compositionHow different dietary patterns influence metabolic health in different waysWhy recommendations around saturated fat and full-fat dairy remain controversialHow historical beliefs and evolving evidence shape nutrition guidelinesThis discussion also highlights a critical point: nutrition science is complex, and population-wide recommendations don’t always translate clearly to individual health.While both organizations emphasize whole foods and reducing processed sugars and refined grains, the DGA reflects a growing recognition that there is more than one way to eat well, while the AHA continues to take a more prescriptive stance on saturated fat and animal-based foods.💡 Learn more about the role of saturated fat and animal products in a well-formulated ketogenic diet on our blog: Understanding the Well-Formulated Ketogenic Diet🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #DietaryGuidelinesExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

People with treatment-resistant depression and anxiety are seeing real improvements through ketogenic therapy. Now there's real-world clinical data to back it up.In this interview, Dr. Bret Scher sits down with Dr. Erin Bellamy to discuss her newly published findings from a clinical program bringing ketogenic therapy into everyday mental health care.While this was not a randomized controlled trial, the results offer an important look at how these interventions may work in everyday clinical practice, with meaningful improvements reported across both depression and anxiety measures.In this conversation, you’ll learn:What the study found and how to interpret the resultsThe difference between real-world evidence and randomized trialsWhy some individuals were able to achieve clinically meaningful improvements, including remissionThe role of structure, education, and ongoing support in implementing ketogenic therapyCommon challenges people face and how group support can help navigate themHow ketogenic therapy can be personalized based on individual needsThe real-life improvements participants experienced in mood, anxiety, daily functioning, and quality of lifeDr. Bellamy also shares powerful insights from her clinical experience, including how individuals with long-standing, treatment-resistant symptoms were able to make meaningful lifestyle changes, challenging the idea that people with mental health conditions cannot adhere to dietary interventions.Looking ahead, Dr. Bellamy is launching a new study through the Metabolic Psychiatry Scholar Award to further explore and scale this approach.Learn more about the impact of metabolic therapies on depression and mood disorders on our Depression Topic Page: https://www.metabolicmind.org/resources/topics/keto-for-depression/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #DepressionExpert Featured:Dr. Erin BellamyIKRT.orghttps://x.com/ikrt_orghttps://www.instagram.com/ikrt_org/Resources Mentioned:Papershttps://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1751564/fullVideoshttps://www.youtube.com/watch?v=LXvKhdRqXiwAdditional resourceshttps://www.metabolicmind.org/resources/awards/(Metabolic Psychiatry Scholar Award)IKRT.org/trialFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Are we turning to ADHD and depression medications too quickly for kids?The Wall Street Journal and New York Times recently published powerful investigations into the overuse of psychiatric medications in children. In this video, Dr. Bret Scher unpacks the key takeaways, the risks of polypharmacy, and why a comprehensive, root-cause approach is more important than ever for kids facing mental health challenges.🔍 In this episode, Dr. Scher covers:The risks of overmedicating: side effects, polypharmacy, and long-term consequencesWhy behavioral therapy is being overlooked, even though it's supposed to be first-lineHow nutrition and metabolic health impact focus, mood, and behavior in kidsWhy low-carb and ketogenic therapies may offer new hopeThe growing research into metabolic therapies for pediatric mental healthAs the youth mental health crisis continues to worsen, it's time we examine our current treatment options and consider what's missing and how we can prioritize nutrition, behavioral therapy, and safer first-line care.👉 To learn more about ketogenic therapy for youth mental health, check out our Youth Mental Health Hub: https://www.metabolicmind.org/resources/topics/youth-mental-health/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #YouthMentalHealth #ADHDExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Millions of Kids Are on ADHD Pills. For Many, It’s the Start of a Drug Cascade.https://www.wsj.com/health/wellness/kids-adhd-drugs-medication-06dfa0b7?gaa_at=eafs&gaa_n=AWEtsqcVhhl0bubzA_1q6yvfc7z3u0t44jw3AzUR9AZSyNO6avhB6NAoOJw72qVmojw%3D&gaa_ts=692b4191&gaa_sig=J0FYmn3CRlIzfq4EpHUykmVvbcGCu-cxuLnKihjrGx1rkjdeoIP693bQ3368UEKDGO2StTwq0maWdWb1L_TTdA%3D%3DWhat to Know About Teen Sexual Development and S.S.R.I.shttps://www.nytimes.com/2025/11/12/magazine/what-to-know-teen-sexual-development-ssris.htmlOxford’s Keto for ADHD & Depression Randomized Controlled Trial – with Ally Houstonhttps://www.metabolicmind.org/resources/news-views/podcasts/metabolic-mind-podcast/oxfords-keto-for-adhd-depression-randomized-controlled-trial-with-ally-houston/What Happens When Kids Try Keto for Bipolar? featuring Elizabeth Erricohttps://www.metabolicmind.org/resources/news-views/podcasts/metabolic-mind-podcast/what-happens-when-kids-try-keto-for-bipolar-featuring-elizabeth-errico/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

If you carry the ApoE4 gene, you’ve likely been told your risk for Alzheimer’s disease is significantly higher. But what does that really mean, and how much control do you actually have?In this video, Dr. Bret Scher breaks down the science behind ApoE4, one of the strongest genetic risk factors for Alzheimer’s disease, and explains why increased risk does not mean a predetermined outcome.You’ll learn how ApoE4 may influence brain health through inflammation, lipid metabolism, and energy use, and why lifestyle and environment play a critical role in shaping these pathways.This video also explores:Why ApoE4 does not guarantee Alzheimer’s diseaseWhat research shows about traditional populations with low dementia ratesHow metabolic health, diet, and lifestyle may influence brain agingNew research challenging common assumptions about meat, fat, and dementia riskThe role of key nutrients like B12, iron, and amino acids in brain functionDr. Scher also reviews recent observational studies suggesting that higher meat consumption may be associated with lower dementia risk in ApoE4 carriers, challenging long-standing dietary narratives.The takeaway: your genes are one piece of the puzzle. Your daily choices, environment, and metabolic health may play a powerful role in shaping long-term brain outcomes.💡 To learn more about metabolic approaches to brain and mental health, visit metabolicmind.org🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #FoodAsMedicine #AlzheimersDiseaseExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Meat Consumption and Cognitive Health by APOE GenotypeDOI: https://doi.org/10.1001/jamanetworkopen.2026.6489A gradient risk of cognitive impairment with vegetarian diets in older adults: highest for vegan and potential benefit for pescatarianDOI: https://doi.org/10.1016/j.foodres.2026.118455Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

How do we actually define “healthy food”? And how is it possible that processed, sugary cereals like Lucky Charms score higher than natural foods like eggs and meat in some food scoring systems?Dr. Bret Scher sits down with Dr. Ty Beal to explore a newly developed nutritional value scoring system designed to better reflect nutrient density, bioavailability, and chronic disease risk.Unlike many existing systems that can produce confusing or counterintuitive rankings, this approach aims to take a more comprehensive and transparent look at what makes food truly nourishing.In this interview, you’ll learn:Why many popular food scoring systems fall shortWhat “nutrient density” really means and why it’s more complex than it soundsHow bioavailability, protein quality, and nutrient diversity factor into food qualityThe role of ultra-processing, fiber, omega-3s, and nutrient ratios in shaping health outcomesWhy animal-source foods like meat, fish, eggs, and dairy can play an important role in a healthy dietHow this system can be adapted to different dietary patterns, including plant-based, omnivorous, and ketogenic approachesDr. Beal also shares the challenges of developing a system like this, from navigating scientific trade-offs to facing intense peer review, and why transparency and flexibility are essential when translating nutrition science into real-world tools.Importantly, this scoring system offers a framework to help individuals, clinicians, and policymakers better understand food quality within the context of overall dietary patterns and metabolic health. Rather than relying on overly simplistic labels like “good” or “bad,” tools like this can help guide more informed, personalized decisions.💡 Explore more resources on metabolic health, mental health, and the current state of nutrition research atmetabolicmind.org🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #FoodAsMedicine #NewPublicationExpert Featured:Dr. Ty Bealtybeal.comhttps://x.com/TyBealPhDhttps://www.instagram.com/tybealphd/Resources Mentioned:Nutritional Value Score Rates Foods Based on Nutrient Density and Noncommunicable Disease Preventionhttps://jn.nutrition.org/article/S0022-3166(26)00092-1/fulltextFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Nurturing your relationship with yourself and your body can play a meaningful role in how you move forward from a mental health setback.Nicole Laurent shares a grounded, compassionate perspective on navigating setbacks. She explores how these moments can sometimes disrupt trust in ourselves, creating an internal tension that makes progress feel harder than it needs to be.She explores:Why setbacks can shake trust in your body, and how to rebuild itHow to approach challenges with curiosity instead of self-judgmentCommon triggers that can lead to going off trackHow mindset and framing influence long-term successHow your relationship with food and your body can evolve over timeThe key takeaway: setbacks are part of the learning process. Reconnecting with the idea that your body is working toward balance can help you move forward with more clarity, confidence, and resilience.💡Learn more about navigating setbacks on the mental health journey in our blog: How to Bounce Back from Challenges and Setbacks.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatryExpert Featured:Nicole Laurent, LMHChttps://mentalhealthketo.com/nicole-laurent-lmhc-about-me/https://x.com/KetoCounselorhttps://www.linkedin.com/in/nlaurent/https://www.instagram.com/mentalhealthketo/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is high LDL cholesterol always a red flag?For a growing group of people known as Lean Mass Hyper-Responders (LMHRs), the answer might not be so black and white.In this video, Dr. Bret Scher unpacks the science and questions behind LMHRs—metabolically healthy, lean individuals who see a dramatic rise in LDL cholesterol after starting a ketogenic diet. Unlike people with familial hypercholesterolemia (FH), their elevated LDL occurs in a unique metabolic context: low insulin, high HDL, low triglycerides, excellent metabolic health, and comes on only after adopting a ketogenic diet.🔍 In this video, you'll learn:• What defines a Lean Mass Hyper-Responder• Why conventional cholesterol risk frameworks may not apply to LMHRs• The key differences between LMHRs and those with familial hypercholesterolemia• Why context, like insulin sensitivity and metabolic health, might matter• Why this phenomenon deserves thoughtful study, not assumptionsThis growing curiosity around LMHRs is the focus of a powerful new documentary: The Cholesterol Code. Featuring researchers, clinicians, and individuals living with this phenotype, the film challenges long-held beliefs about cholesterol, risk, and metabolic health, and opens the door to a more nuanced conversation🎬 Real change starts with real conversations. Join us in sharing The Cholesterol Code, a powerful film that challenges outdated thinking about cholesterol and heart health. Sign up to host a screening or find one near you at 🔗 https://cholesterolcodemovie.com/host-a-screening/.Together, we can reach the people who need this most.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicine #LDLCholesterolExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:https://cholesterolcodemovie.comFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Are we destined for cognitive decline as we age, or do we have more control than we think?In this conversation, Dr. Bret Scher sits down with neuroscientist and researcher Dr. Tommy Wood to explore a powerful shift in how we think about brain health, aging, and dementia prevention.Dr. Wood challenges the common belief that cognitive decline is inevitable, highlighting how lifestyle, environment, and daily habits can meaningfully shape our brain’s trajectory over time. He introduces his “3S Framework”—Stimulus, Supply, and Support—to explain how brain function is built, maintained, and optimized across the lifespan.In this interview, you’ll learn:Why cognitive decline isn’t inevitableHow mindset and engagement can influence brain agingThe role of metabolic health and energy supply in brain functionHow nutrition, sleep, exercise, and social connection interact to support the brainWhere ketogenic therapy and ketones may fit into brain health and cognitive declineHow to navigate modern challenges like technology, AI, and information overload from a brain health perspectiveDr. Wood also shares insights from his upcoming book, The Stimulated Mind, offering a practical framework to help individuals “future-proof” their brain and stay sharp in an ever-changing world.The key takeaway: brain health isn’t about a single intervention. It’s about consistently engaging, fueling, and supporting the brain in ways that promote resilience over time.💡 To learn more about metabolic approaches to brain and mental health, visit metabolicmind.org or sign up fo the Metabolic Mind newsletter at metabolicmind.org/newsletter🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #DementiaExpert Featured:Dr. Tommy Woodhttps://www.drtommywood.com/https://www.instagram.com/drtommywood/Resources Mentioned:Dr. Wood's Bookhttps://www.drtommywood.com/stimulated-mindGoogle effects on memory: cognitive consequences of having information at our fingertipshttps://pubmed.ncbi.nlm.nih.gov/21764755/Adult Changes in Thought study: dementia is an individually varying convergent syndrome with prevalent clinically silent diseases that may be modified by some commonly used therapeuticshttps://pubmed.ncbi.nlm.nih.gov/22471861/Dietary cholesterol or egg consumption do not increase the risk of stroke, Finnish study findshttps://www.sciencedaily.com/releases/2019/05/190520093448.htmMultimodal strategy to rescue the brain in mild cognitive impairment: Ketogenic oral nutrition supplementation with B vitamins and aerobic exercisehttps://pmc.ncbi.nlm.nih.gov/articles/PMC9541319/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

In this second video of our Bounce Back Series, Dr. Georgia Ede shares practical, compassionate guidance for returning to ketosis using simple, effective strategies rooted in diet and lifestyle.Rather than approaching setbacks with frustration or perfectionism, Dr. Ede emphasizes a mindset of curiosity and learning. Falling out of ketosis will happen and it’s not a failure. With the right tools, you can use that information to refine what works best for your body.In this video, you’ll learn:Why “ketosis interruptions” are normal and part of the processHow mindset plays a critical role in long-term successSimple strategies to return to ketosis quickly, including fasting and exerciseHow food choices can support appetite regulation and metabolic stabilityThe role of supplements like exogenous ketones and their limitationsWhy personalization is key to sustainable metabolic healthDr. Ede also explains the underlying physiology of ketosis: how insulin, glucose, and stored glycogen influence your body’s ability to shift back into fat-burning mode.The key takeaway: consistency matters, but perfection isn’t required. With the right approach, you can recover quickly, learn from the experience, and continue moving forward.💡Learn more about navigating setbacks on the mental health journey in our blog: How to Bounce Back from Challenges and Setbacks.Check out part 1 of this series: https://youtu.be/C4KCNIO31tM🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatryExpert Featured:Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

If you only read the headlines, it sounds simple: plants are protective, red meat is harmful. But when you examine the actual studies behind those claims, the conclusions aren’t nearly so clear.In this video, Dr. Bret Scher takes a closer look at two recently published papers, one linking red meat consumption to diabetes risk and another suggesting vegetarian diets reduce cancer risk. Both studies rely on observational nutrition data, which can reveal associations but cannot prove cause and effect.In this video, you'll learn:Why many nutrition headlines oversimplify complex researchThe difference between observational studies and causal evidenceHow healthy user bias and lifestyle confounding can distort resultsWhy hazard ratios in nutrition studies are often too small to draw meaningful conclusionsHow media coverage and expert commentary can reinforce existing dietary narrativesDr. Scher explains why these studies may say more about overall lifestyle patterns like calorie intake, diet quality, alcohol use, and smoking, than about individual foods like red meat or plant-based diets.The bigger takeaway: nutrition science is nuanced, and the best diet for metabolic health may vary from person to person. Instead of focusing on simplistic narratives like “meat bad, plants good,” we should focus on improving overall dietary quality and metabolic health.💡If you’re looking for deeper, more nuanced discussions about nutrition, metabolic health, and mental health, explore our resources at metabolicmind.org.#MetabolicMind #KetogenicTherapy #FoodAsMedicine🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Vegetarian diets and cancer risk: pooled analysis of 1.8 million women and men in nine prospective studies on three continentshttps://www.nature.com/articles/s41416-025-03327-4Association between red meat intake and diabetes: a cross-sectional analysis of a nationally representative sample of US adults (NHANES 2003-2016)https://pubmed.ncbi.nlm.nih.gov/41667215/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

In this special episode of Metabolic Mind, Dr. Julie Milder, Director of Neuroscience at Baszucki Group, speaks with Dr. Fabiano Gomes, psychiatrist and researcher at McMaster University, and the inaugural recipient of the Baszucki Group Metabolic Psychiatry Scholar Award.Dr. Gomes recently published a pilot feasibility trial of a ketogenic diet for depression in the Journal of Affective Disorders. In this conversation, he shares how the study came together, what the results revealed, and why metabolic approaches may offer new hope for people struggling with treatment-resistant depression.In this episode, they discuss:The pilot ketogenic diet trial for depression and its key findingsHow the study successfully transitioned to a fully remote clinical trial during COVIDWhat the results suggest about feasibility, adherence, and clinical improvementsThe role of nutritional ketosis in mood disorders and metabolic psychiatryDr. Gomes’ vision for launching a Metabolic Psychiatry Clinic in CanadaPlans to integrate biomarkers, brain imaging, and real-world clinical careThe importance of training clinicians and dietitians to expand access to metabolic therapiesDr. Gomes’s work represents an exciting step forward in the growing field of metabolic psychiatry, which explores how metabolism and brain energy may influence conditions like depression, bipolar disorder, and other mental health disorders.The conversation also highlights the importance of building clinical infrastructure and training programs to make metabolic therapies more accessible to patients today.💡Learn more about the growing research on metabolic psychiatry and depression on our Depression Topic Page: https://www.metabolicmind.org/resources/topics/keto-for-depression/👍 If you found this discussion helpful, please like and subscribe for more conversations about metabolic health and mental health.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #DepressionExpert Featured:Dr. Julie Milderhttps://www.metabolicmind.org/team/julie-milder-phd/http://linkedin.com/in/juliemilderDr. Fabiano Gomeshttps://www.instagram.com/dr.fabianogomes/linkedin.com/in/fabiano-gomes-b03b492a/https://x.com/fagomes1981Resources Mentioned:https://canbind.ca/Medically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot studyhttps://doi.org/10.1016/j.jad.2025.121079Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Setbacks are a natural part of any journey, and mental health recovery is no exception. In this video, Dr. Matt Bernstein shares a powerful perspective on why downturns aren’t failures, but opportunities to learn, adapt, and build resilience.Rather than viewing setbacks as something to fear or avoid, Dr. Bernstein explains how adopting a growth mindset can transform the way we respond to challenges. With the right preparation and support, moments of struggle can become key turning points in long-term recovery.In this video, you’ll learn:Why setbacks are normal in any recovery journeyHow to reframe “failures” as opportunities for growthThe importance of identifying early warning signsHow to build a personal plan for navigating downturnsWhy support systems and connection are critical during difficult timesHow tools like mindfulness and structured planning can help you regain momentumDr. Bernstein also discusses practical strategies like creating a Wellness Recovery Action Plan, leveraging your support network, and even planning ahead for more serious crises with tools like a healthcare proxy.If you’re navigating mental health challenges or supporting someone who is, this conversation offers practical tools and a more compassionate framework for the journey.💡Learn more about navigating setbacks on the mental health journey in our detailed article: How to Bounce Back from Challenges and Setbacks.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatryExpert Featured:Dr. Matt Bernsteinhttps://accordmh.com/http://linkedin.com/in/matthew-bernstein-md-5743338Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can a ketogenic diet improve mental health?This week marks a significant moment for metabolic psychiatry and ketogenic therapy for serious mental illness.A New York Times piece highlighted early research from Stanford University, The Ohio State University, and the University of Edinburgh—alongside stories from individuals who have shared their lived experience here on Metabolic Mind.This kind of visibility matters. It reflects years of work by researchers and clinicians like Drs. Chris Palmer, Shebani Sethi, and Iain Campbell, research funded by Baszucki Group, advocates like Jan Baszucki, as well as the many people who have been willing to share their personal stories.Lived experience alone isn’t enough. Early data alone isn’t enough. But together, they point to something that must be tested, confirmed — or challenged — through high-quality science. That’s why we are excited about several RCTs currently completed or underway around the world.We need to continue efforts to advance education, public awareness and research on a scale that will require public funding. That’s how medicine moves forward. And that’s the exciting work ahead.📰 Read the full article here: https://nyti.ms/4sj2WZDHear more from our founder Jan Baszucki, calling for further investments in research and clinical care, and sharing her family’s story highlighting how after a decade of illness, ketogenic therapy sent her son's bipolar I disorder symptoms into remission and has kept him there since 2021.🔗 Read Jan’s op-ed: https://bit.ly/4dpkU7Z🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:NYT Article: Can the Keto Diet Really Improve Mental Health?https://nyti.ms/4sj2WZDFoundational Clinical Trials Pagehttps://www.metabolicmind.org/resources/science/clinical-trials/Maya Schumer’s THINK+SMART Profile:https://www.metabolicmind.org/thinksmart/explore-strategies/maya-schumer/Lewis Anstee’s THINK+SMART Profile:https://www.metabolicmind.org/thinksmart/explore-strategies/lewis-anstee/Lived Experience Stories & Strategieshttps://www.metabolicmind.org/thinksmart/explore-strategies/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can the ketogenic diet help improve symptoms for individuals living with treatment-resistant depression?In this conversation, Dr. Bret Scher sits down with Dr. Megan Kirk Chang, a senior researcher in metabolic psychiatry at the University of Oxford and a co-author of the recently published DIME trial.This study represents the first randomized clinical trial to evaluate a ketogenic diet in adults with treatment-resistant depression.Participants were assigned to either a ketogenic diet or a plant-rich comparison diet for six weeks to assess whether dietary intervention could influence depressive symptoms. Both groups experienced meaningful improvements in depression scores, with the ketogenic diet slightly outperforming the control group at 6 weeks.While the difference between groups did not reach the threshold for statistical significance, the findings suggest a positive signal that warrants further investigation.In this interview, Dr. Kirk Chang reflects on:The strengths of the study and where she sees opportunity for improvement.What the modest difference between diets might meanWhy early pilot trials are designed to detect signals rather than definitive answersWhat the study revealed about adherence, cravings, and behavioral factorsHow these results will inform larger and longer clinical trials now being plannedAs Dr. Kirk Chang explains, this six-week pilot trial was designed as proof-of-concept research to determine whether there is enough signal to justify larger studies in metabolic psychiatry.At Metabolic Mind, we view studies like this as an important step in a growing scientific effort to understand how metabolism and nutrition may influence serious mental illness. Each new study contributes to the evolving evidence base that will help researchers determine who may benefit, why, and under what conditions.🔗 To learn more about the available evidence for ketogenic therapy in depression and our top resources, visit our Depression Topic Page: https://www.metabolicmind.org/resources/topics/keto-for-depression/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Megan Kirk Chang, PhDSenior Researcher, Department of Psychiatry, University of Oxfordhttps://x.com/DrMegKirkChanghttps://www.linkedin.com/in/megankirkchang/Resources Mentioned:A Ketogenic Diet for Treatment-Resistant Depression: A Randomized Clinical Trialhttps://doi.org/10.1001/jamapsychiatry.2025.4431Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

A new meta-analysis just dropped, and once again, saturated fat takes center stage. But does the data actually support the decades-long warnings we've heard about saturated fat and heart disease? Not exactly.In this video, Dr. Bret Scher dives deep into a recent study published in the Annals of Internal Medicine that reviewed randomized controlled trials on saturated fat intake and health outcomes.Despite the headlines and abstract language hinting at risk, a closer look at the data reveals no statistically significant increase in heart attacks, strokes, or early death, even with modest increases in LDL.So why the disconnect between what the data shows and what the authors claim? Dr. Scher breaks it down and explores the nuances often missing from the conversation about saturated fat, including context like food quality, carbohydrate intake, metabolic health, and lifestyle factors that make a big difference.🔍 Key Topics Covered:What this new meta-analysis actually found (vs. what it claimed)The persistent bias in nutrition science and reportingWhy LDL isn’t the whole storyHow dietary context, like carbs, processing, and lifestyle, matters more than saturated fat aloneWhy focusing on whole dietary patterns is essential for metabolic healthDr. Scher says it best, “If the medical and dietetic institutions are so certain that saturated fat is harmful, why are there so many studies that fail to reach meaningful conclusions?”To learn more about ketogenic therapy and heart disease, check out our Is Keto Safe Topic Page for more content from cardiologist Dr. Bret Scher breaking down keto, dietary fat, saturated fat, LDL, and more.https://www.metabolicmind.org/resources/topics/is-keto-safe/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Effect of Interventions Aimed at Reducing or Modifying Saturated Fat Intake on Cholesterol, Mortality, and Major Cardiovascular Events: A Risk Stratified Systematic Review of Randomized Trialshttps://doi.org/10.7326/ANNALS-25-02229Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

You may have seen headlines or social media posts claiming that ketones increase the risk of heart attacks and that this proves ketogenic diets are dangerous for heart health. But when you actually examine the study behind those claims, the data tell a very different story.In this video, Dr. Bret Scher takes a closer look at a recent paper published in the Journal of the American Heart Association that analyzed circulating ketone levels in participants from the UK Biobank. The study has been widely shared online as evidence against ketogenic diets. The issue? The participants weren’t following a ketogenic diet at all.Instead, researchers measured very small baseline ketone levels in a general population that was consuming around 250 grams of carbohydrates per day, that’s far from the levels associated with nutritional ketosis.In this video, you’ll learn:Why this study was not a ketogenic diet studyThe difference between association and causation in epidemiologyWhy the measured ketone levels were far below nutritional ketosisHow metabolic stress, illness, or diabetes can raise ketone levels independently of dietWhy these findings don’t tell us anything about ketogenic dietsUnderstanding the context behind nutrition research is critical. Misinterpreting observational data can easily lead to misleading headlines and unnecessary confusion about diet and health.💡If you want to learn more about the science behind ketogenic metabolic therapy, visit metabolicmind.org for research, resources, and expert insights.👍 If you found this helpful, like and subscribe for more evidence-based discussions about metabolic health and mental health.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicineExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Circulating Ketone Bodies and Incident Cardiovascular Outcomes and Mortality: Insights From the UK Biobankhttps://www.ahajournals.org/doi/10.1161/JAHA.125.042582Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can you reverse fatty liver disease with a ketogenic diet?Fatty liver disease is now one of the fastest-growing liver conditions in the world, affecting roughly 30% of adults and an increasing number of children. And in many cases, it’s driven by metabolic dysfunction and insulin resistance.In this conversation, Dr. Bret Scher speaks with Dr. Amy Goss (University of Alabama at Birmingham) and Dr. Karen Jerome-Zapadka (Trajectory Health Partners) about the growing epidemic of metabolic dysfunction–associated steatotic liver disease (MASLD) and why carbohydrate restriction and ketogenic nutrition may be powerful tools for addressing it.In this interview, you’ll learn:What MASLD (formerly NAFLD) is and why it’s becoming so commonHow insulin resistance and excess carbohydrates contribute to fatty liverNew research showing how carbohydrate restriction can reduce liver fatWhy ketogenic and low-carb diets may improve liver metabolism beyond weight lossThe clinical experience of reversing fatty liver through metabolic therapyWhy lifestyle approaches often receive less attention than medicationsDr. Amy Goss and her team at the University of Alabama at Birmingham are currently conducting a large NIH-funded clinical trial investigating how carbohydrate restriction affects liver fat and insulin sensitivity in adolescents with fatty liver disease.At the same time, Dr. Karen Jerome-Zapadka is applying these metabolic principles in clinical practice at Trajectory Health Partners, helping patients reverse steatotic liver disease through carbohydrate reduction and comprehensive metabolic care. Together, their research and real-world clinical experience are helping advance a deeper understanding of how targeting metabolic dysfunction may transform the way fatty liver disease is treated.Curious about the safety of ketogenic therapy? Visit our Is Keto Safe topic page to see all of our top content on the topic: https://www.metabolicmind.org/resources/topics/is-keto-safe/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #MASLD #FattyLiverExpert Featured:Dr. Amy Miskimon Gosshttps://www.instagram.com/dr.amygoss/www.linkedin.comDr. Karen Jerome-ZapadkaTrajectoryhp.cominstagram.com/kzapadkahttps://www.linkedin.com/in/karen-jerome-zapadka-md-dabom-mhp-581b22113/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

A new meta-analysis of 174 randomized controlled trials on “carbohydrate-restricted diets” found consistent benefits for body composition, blood pressure, inflammation, and more. But instead of highlighting the metabolic benefits, most of the headlines focused almost entirely on a small bump in LDL.In this video, Dr. Bret Scher breaks down why that reaction misses the point and how biases in nutrition reporting are holding back real progress in improving metabolic health.📌In this video, you’ll learn:How the authors classified “carbohydrate-restricted diets”The many health benefits associated with restricting carbohydratesWhat impact low carbohydrate diets had on LDL levelsWhether or not we should sound the alarm on LDL increasesThe double standard in how we talk about diet vs. diabetes drugs that may produce increases in LDLWhat matters more than LDL alone when assessing metabolic riskWhether you're a patient or a practitioner, it’s essential to look beyond sensational headlines and focus on the full body of evidence, especially when it comes to nutrition and cardiovascular risk. Clear and balanced conversations are more important than ever if we want to turn the tide on metabolic disease.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.👉 Subscribe to Metabolic Mind to stay up-to-date on the latest in metabolic psychiatry, low-carb nutrition, and brain health: https://www.youtube.com/@metabolicmind.#MetabolicMind #KetogenicTherapy #MetabolicDiseaseExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Effects of carbohydrate-restricted diets and macronutrient replacements on cardiovascular health and body composition in adults: a meta-analysis of randomized trialshttps://doi.org/10.1016/j.ajcnut.2025.09.012Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Are there real contraindications to a ketogenic diet? Yes, but they’re far rarer than many people think. So who shouldn’t do keto?In this video, Dr. Bret Scher breaks down the difference between absolute and relative contraindications to ketogenic therapy. While rare inborn metabolic disorders and certain acute illnesses are true absolute contraindications, most commonly cited concerns, including type 1 or type 2 diabetes, heart disease, serious mental illness, high cholesterol, and even pregnancy are listed as relative contraindications, which really means, “use caution and work with an experienced clinician.”Watch to learn who should avoid ketogenic therapy, who may benefit, and why clinical guidance makes all the difference.👉To learn more about the safety and efficacy of ketogenic therapy, check out our “Is Keto Safe?” topic page: https://www.metabolicmind.org/resources/topics/is-keto-safe/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicineExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Clinician Directorieshttps://www.metabolicmind.org/peers-families/get-help/Can a Keto Diet Cause Hypomania, and How Can It Be Avoided?https://www.youtube.com/watch?v=F11ZBvCjVNkFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Ketogenic therapy for schizophrenia, bipolar disorder, and depression is gaining attention, but how can it be safely implemented into clinical practice?A newly published expert consensus provides practical recommendations to help clinicians thoughtfully apply ketogenic metabolic therapy (KMT) for serious mental illnesses.In this in-depth conversation, Dr. Matt Bernstein and Dr. Georgia Ede, both members of the expert committee, discuss how this Delphi consensus was developed, what it includes, and how it can be responsibly integrated into psychiatric practice.In this interview, they discuss:What a Delphi process is and why it was usedThe results of the Delphi process (33 consensus statements and 10 clinical recommendations)Who may be appropriate candidates for KMTAbsolute and relative contraindicationsRecommended laboratory screening and monitoringHow long a trial should last before assessing efficacyHow clinicians can personalize implementation safelyImportantly, the authors emphasize that ketogenic metabolic therapy is not a replacement for standard psychiatric treatment. Rather, it may be considered alongside first-line therapies, particularly for individuals who have not responded adequately, cannot tolerate medications, or are seeking additional options.Reflecting on the value of this work, Dr. Bernstein shares:“I would have loved to have read this six years ago when I was starting to think about implementing these types of practices. It would have given me confidence to charge forward… I probably would have been further along now than I am.”With randomized controlled trials ongoing and more research expected in the coming years, this consensus provides a thoughtful, experience-informed framework for clinicians who are seeing growing interest in metabolic approaches.If you are a clinician, we encourage you to read the full publication.If you are a patient or family member, consider sharing this interview and the paper with your care team to support an informed discussion about whether metabolic strategies may be appropriate in your individual case.As always, clinical decisions should be made in partnership with qualified healthcare professionals.📚 Read the Paper: Published in Frontiers in Nutrition: https://doi.org/10.3389/fnut.2026.1749406🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Georgia EdeHarvard-Trained Psychiatristhttps://www.diagnosisdiet.com/Dr. Matthew BernsteinCEO of Accord: https://accordmh.com/https://www.linkedin.com/in/matthew-bernstein-5743338/Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Awareness and Best Practices in using Ketogenic Therapy to Treat Serious Mental Illness: A Modified Delphi Consensushttps://doi.org/10.3389/fnut.2026.1749406Ketogenic Diets for Mental Health Clinician Training Coursehttps://www.diagnosisdiet.com/trainingFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

How can doctors, psychiatrists, and other health practitioners implement keto for serious mental illnesses like schizophrenia, bipolar disorder, and depression?In this short interview, Dr. Bret Scher sits down with Dr. Georgia Ede to discuss a newly published Delphi consensus paper in Frontiers in Nutrition, authored by eight experienced clinicians and researchers to establish best practices for the use of ketogenic metabolic therapy (KMT) in serious mental illnesses.Using a structured expert consensus process, the group created 33 statements clarifying things like:What ketogenic metabolic therapy isWho may be appropriate candidates?Safety considerations and medical screeningMonitoring standards and clinical implementationHow KMT can be integrated alongside standard psychiatric careThese statements were then brought to a larger group of experienced clinicians to assess broader consensus, which resulted in all 33 statements reaching the consensus threshold.This paper is not a set of formal treatment guidelines. Instead, they represent an important first step in delivering practical, experience-informed guidance for clinicians who are seeing growing patient interest in metabolic approaches to serious mental illnessAs research continues to evolve, this consensus provides a thoughtful framework for psychiatrists, primary care clinicians, therapists, dietitians, and multidisciplinary teams who wish to incorporate ketogenic metabolic therapy into individualized treatment plans.If you are a clinician interested in learning more about metabolic approaches in psychiatry, we encourage you to explore the full publication.If you are a patient or family member, consider sharing this paper with your care team to start an informed discussion about whether metabolic strategies may be appropriate in your individual case.With the clinical evidence still accumulating and randomized controlled trials ongoing, we expect this clinical guidance to continue to evolve as more data and real word experience becomes available.📚 Read the Paper: Published in Frontiers in Nutrition: https://doi.org/10.3389/fnut.2026.1749406#MetabolicMind #KetogenicTherapy #MetabolicPsychiatry🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Georgia EdeHarvard-Trained Psychiatristhttps://www.diagnosisdiet.com/Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Awareness and Best Practices in using Ketogenic Therapy to Treat Serious Mental Illness: A Modified Delphi Consensushttps://doi.org/10.3389/fnut.2026.1749406Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Polycystic Ovary Syndrome (PCOS) is the leading cause of infertility in women, but what if the real issue isn’t the ovaries?In this eye-opening conversation, Dr. Bret Scher speaks with Dr. Steven Palter, reproductive endocrinologist and founder of Gold Coast IVF, about the powerful connection between PCOS, metabolic health, mental health, and fertility.For decades, PCOS has been treated symptom-by-symptom: birth control for irregular cycles, fertility drugs for ovulation, IVF for infertility. But Dr. Palter explains why this approach often misses the root cause: insulin resistance and metabolic dysfunction.When you address the metabolic driver, everything can change.Ketogenic and low-carbohydrate dietary approaches are showing promise in improving insulin sensitivity, restoring ovulation, improving mood, and even supporting fertility, often before significant weight loss occurs. In many cases, women who were preparing for IVF are conceiving naturally after correcting their metabolic health.In this video, you’ll learn:Why PCOS is best understood as a metabolic disorderHow insulin resistance drives infertility, mood changes, and long-term health risksWhy traditional “eat less, move more” advice often failsHow ketogenic therapy may restore ovulation and improve fertilityThe connection between PCOS, depression, and binge eatingWhy GLP-1 medications aren’t the same as metabolic repairIf you or someone you know is struggling with PCOS, infertility, or unexplained hormonal symptoms, this episode offers a hopeful and science-based perspective on what’s possible when metabolic health becomes the priority.As always, consult your healthcare provider before making significant dietary changes.💡Learn more about the safety and efficacy of ketogenic therapy on our “Is Keto Safe?” topic page: https://www.metabolicmind.org/resources/topics/is-keto-safe/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #PCOS #InsulinResistanceExpert Featured:Dr. Steven Palterhttps://www.instagram.com/stevenpaltermdhttps://www.tiktok.com/@stevenpaltermdhttps://www.youtube.com/@StevenPalterMDhttps://www.facebook.com/@stevenpaltermdResources Mentioned:https://www.goldcoastivf.com/pcosbaby.comFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

February is Heart Health Month, making it the perfect time to challenge common misconceptions about diet and cardiovascular health.One claim that always resurfaces? That ketogenic diets are bad for your heart. But when you take a closer look at the science, that assumption simply doesn’t hold up.In this video, Dr. Bret Scher breaks down the real evidence behind ketogenic diets and cardiovascular risk, addressing:✅ How many “keto” studies don’t actually study true ketogenic diets✅ The truth about LDL cholesterol on keto (it doesn’t go up for everyone!)✅ Why triglycerides, HDL, insulin, and inflammation may matter more than LDL✅ How keto compares to DASH for blood pressure and metabolic health✅ Why saturated fat from real food behaves differently in the body✅ The critical difference between ultra-processed high-fat/high-carb diets and low-carb, whole-food ketogenic diets💡 Using the most up-to-date clinical evidence, Dr. Scher explains why ketosis can be a heart-supportive strategy, especially for those with type 2 diabetes, hypertension, insulin resistance, or poor metabolic health.If you’re interested in learning more about the safety of ketogenic therapy, check out our “Is Keto Safe” topic page: https://www.metabolicmind.org/resources/topics/is-keto-safe/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicine #HeartHealthExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is there evidence that the ketogenic diet can cure schizophrenia?Recent comments from HHS Secretary Robert F. Kennedy Jr. sparked headlines…and controversy. While “cure” isn’t the right word, the conversation has brought much-needed attention to an emerging field: metabolic psychiatry.In this video, Dr. Bret Scher breaks down what the science actually shows about ketogenic metabolic therapy as a potential adjunctive treatment for serious mental illness, including schizophrenia, bipolar disorder, and major depressive disorder.You’ll learn about:What nutritional ketosis is and why brain energy matters for serious mental illnessHow psychiatric conditions like schizophrenia, bipolar disorder, and major depressive disorder involve underlying metabolic dysfunctionEarly evidence on ketogenic therapy for serious mental illness from Stanford, Edinburgh, and The Ohio State UniversityHow consistent lived experiences aligned with emerging clinical data warrant serious scientific explorationWhat new research is on the wayKetogenic therapy is emerging as a serious metabolic strategy that may expand how we think about treating complex psychiatric conditions. We are now faced with the opportunity to study it rigorously, apply it thoughtfully, and ensure patients have access to every tool that could help.💡Learn more about the ongoing research in metabolic psychology on our Clinical Trials page: https://www.metabolicmind.org/resources/science/clinical-trials/🏛Check out our condition specific topic pages to see our best resources on keto for serious mental illnesses:Keto for Schizophrenia: https://www.metabolicmind.org/resources/topics/schizophrenia/Keto for Bipolar Disorder: https://www.metabolicmind.org/resources/topics/bipolar/Keto for Depression: https://www.metabolicmind.org/resources/topics/keto-for-depression/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #SchizophreniaExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:A pilot study examining a ketogenic diet as an adjunct therapy in college students with major depressive disorderhttps://doi.org/10.1038/s41398-025-03544-8Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trialhttps://doi.org/10.1016/j.psychres.2024.115866A pilot study of a ketogenic diet in bipolar disorder: clinical, metabolic and magnetic resonance spectroscopy findingshttps://doi.org/10.1192/bjo.2024.841https://www.metabolicmind.org/resources/science/clinical-trials/https://www.metabolicmind.org/thinksmart/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

In this powerful interview, Dr. Bret Scher speaks with Dr. Robin Engelhardt, a German researcher and PhD in psychology, who is launching a pilot study investigating ketogenic metabolic therapy as a treatment for PTSD and complex PTSD.Using his own personal experience of healing from PTSD through nutritional ketosis, Dr. Engelhardt is now launching a pilot study to explore whether this approach can help others. His pilot study will test feasibility, safety, and symptom response, paving the way for future randomized controlled trials.📘 What you’ll learn in this video:Why Dr. Engelhardt turned to a ketogenic diet for his PTSDWhat existing (though limited) research says about keto and traumaThe mechanisms that might explain why ketosis could benefit PTSD (e.g., improved brain energy, reduced inflammation)How this new feasibility study is structured, and what researchers hope to uncoverThe real-life challenges of implementing therapeutic ketosis for brain healthThis conversation is a rare look at the intersection of personal healing and scientific discovery, and a glimpse into the future of trauma treatment through metabolic approaches. Whether you're a clinician, researcher, or someone impacted by PTSD, this is an interview you won’t want to miss.👉 For more information on metabolic psychiatry and PTSD, check out our blog: Hope for PTSD: The Potential of Ketogenic Metabolic Therapies🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #MetabolicPsychiatry #PTSD #KetogenicTherapyExpert Featured:Robin EngelhardtTo learn more about the study, contact Dr. Engelhardt’s team at [email protected] CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Saturated fat is back in the headlines, and so is the confusion.The new Dietary Guidelines for Americans just dropped, and while there’s clear progress (more support for animal-based protein, low-carb options, and reduced sugar), they’ve kept the 10% cap on saturated fat. But does the science still support that limit, and does it make sense with the rest of the recommendations?In this episode, Dr. Bret Scher breaks down the real story on saturated fat: where the guidelines get it right, where they fall short, and why context is everything when it comes to fat, food, and metabolic health.He covers:✅ The 5 main types of evidence on saturated fat✅ Why source and dietary context matter more than grams✅ What randomized trials, ketogenic studies & LDL data really show✅ The problem with lumping steak and pizza into one category✅ Why blanket limits may harm people trying to improve their metabolic healthThe saturated fat debate isn’t just about grams, it’s about individual metabolic health. When we zoom out and look at the full picture, it becomes clear that not all saturated fat is created equal. Understanding where it comes from and how it fits into an overall dietary pattern is key to moving the conversation forward.👉 Subscribe to Metabolic Mind for more conversations, research, and updates on metabolic health and metabolic psychiatry.#MetabolicMind #KetogenicTherapy #FoodAsMedicine #SaturatedFat🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret Scherhttps://x.com/bschermdhttps://www.linkedin.com/in/bret-scher-08baaa102/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

In this deeply personal and powerful conversation, Metabolic Mind founder Jan Ellison Baszucki joins mental health advocate Laura Delano to share a mother’s journey through her son’s bipolar disorder diagnosis, years of psychiatric crisis, and ultimately, hope.After five years, 29 medications, multiple hospitalizations, and a system that offered few lasting solutions, Jan’s son Matt found real and sustained stability through metabolic therapies, including a therapeutic ketogenic diet.In this conversation, you’ll hear:• What it’s like to navigate the mental health system as a parent• How conventional care fell short, and what was missing• Why Jan calls metabolic psychiatry “energetic medicine for the mind”• How diet, sleep, light, and lifestyle can transform mental health• A powerful message for other families searching for answersThis experience didn’t just transform Jan’s family; it sparked a mission. Jan and her family founded Metabolic Mind to raise awareness about the therapeutic potential of metabolic interventions for serious mental illness. Today, Metabolic Mind is helping to bridge the gap between psychiatry and metabolic health by supporting research, educating clinicians and families, and empowering those still searching for answers.💡Learn more at metabolicmind.org👉 Subscribe to Metabolic Mind for more interviews, research, and updates in the field of metabolic psychiatry.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #BipolarDisorderExpert Featured:Jan Ellison BaszuckiPresident of Baszucki Group and founder of Metabolic Mindhttps://x.com/janellisonhttps://www.instagram.com/jan_ellison_baszucki/https://www.linkedin.com/in/janellisonbaszucki/Laura Delanohttps://www.lauradelano.com/https://www.facebook.com/laurafdelanohttps://www.youtube.com/channel/UCMgs1cXo8Frtf1v7WcNvwuQhttps://www.instagram.com/_lauradelano_/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can a ketogenic diet help with depression when other options have failed? Emerging suggests the answer may be yes.In this video, Dr. Bret Scher shares the latest clinical data on ketogenic therapy for depression, including two new studies showing meaningful improvements, even remission, in people with moderate to severe symptoms. For individuals struggling with treatment-resistant depression, these findings offer real hope and open the door to a new therapeutic pathway: metabolic interventions that target brain energy.In this video, you’ll learn:How ketosis may support brain function and mental healthWhat two new pilot studies reveal about keto for depression and anhedoniaHow researchers are beginning to rethink the metabolic roots of mood disorders🔍 Explore more and dive into the research on our Depression Topic Page: https://www.metabolicmind.org/resources/topics/keto-for-depression/👉 Subscribe to Metabolic Mind for more interviews, research, and updates in the field of metabolic psychiatry.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #Depression #MetabolicPsychiatryExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:A pilot study examining a ketogenic diet as an adjunct therapy in college students with major depressive disorderhttps://doi.org/10.1038/s41398-025-03544-8Medically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot studyhttps://doi.org/10.1016/j.jad.2025.121079Keto For College Depression Bloghttps://www.metabolicmind.org/resources/library/blog/perspectives-in-metabolic-psychiatry/new-research-a-ketogenic-diet-improved-depression-in-college-students/Depression Topic Pagehttps://www.metabolicmind.org/resources/topics/keto-for-depression/THINK+SMART Pagehttps://www.metabolicmind.org/thinksmart/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

The second-ever pilot trial (published in the Journal of Affective Disorders) is making waves: a virtual medically supervised ketogenic diet showed impressive improvements in people with moderate to severe depression, including nearly 7 out of 8 study completers achieving clinical remission.In this interview, Dr. Bret Scher sits down with lead researcher Dr. Elisa Brietzke, Professor of Psychiatry at Queen’s University, to explore the inspiration, execution, and implications of this study.What began as a bold idea, that metabolic dysfunction plays a role in depression, evolved into a fully remote clinical intervention. Despite skepticism and challenges, the results were clear: ketogenic therapy can be safely and effectively implemented in a remote outpatient setting. Participants who completed the study experienced improvements in depression, anxiety, and anhedonia (the loss of pleasure).In this conversation, Dr. Brietzke shares:Why she turned to metabolic therapy for mental healthHow the team pulled off a fully remote ketogenic trial during the pandemicThe science behind how inflammation, insulin resistance, and brain energy affect moodWhy traditional antidepressants often fail to address anhedoniaWhat’s next for research, and how this could shape depression treatment guidelines👉 If you or someone you know is struggling with treatment-resistant depression, learn more about metabolic therapies on our Depression Topic Page: https://www.metabolicmind.org/resources/topics/keto-for-depression/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicine #Depression #AnhedoniaExpert Featured:Dr. Elisa Brietzkehttps://psychiatry.queensu.ca/news/welcome-dr-elisa-brietzkehttps://www.linkedin.com/in/elisa-brietzke-844606281/?originalSubdomain=cahttps://www.instagram.com/dr.elisabrietzke/https://x.com/@e_brietzkeResources Mentioned:Medically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot studyhttps://doi.org/10.1016/j.jad.2025.121079Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

The 2025-2030 Dietary Guidelines for Americans have arrived, and they’re sparking serious debate. Are we finally seeing a meaningful shift toward metabolic health? What do the guidelines get right, and where is there still room for improvement?To unpack it all, Dr. Bret Scher is joined by two long-time voices in nutrition science: Dr. David Ludwig and Gary Taubes. Together, they dig into what the new guidelines get right, what they overlook, and what this all means for public health, clinical practice, and the food industry.They explore:The shifting stance on animal protein, and the controversy it’s stirredA long-overdue move away from refined carbohydratesWhy the term “ultra-processed food” was intentionally left outThe important nod to low-carb diets for chronic diseaseHow school lunches and government food programs may (or may not) changeThe tension between dietary health and environmental goalsWhy robust clinical trials, not just policy documents, are urgently neededThis lively discussion blends agreement, disagreement, and deep insights into what these guidelines mean, not just on paper, but in real life. Whether you're a clinician, policymaker, parent, or just trying to eat healthier, this episode will help you rethink the “official” nutrition narrative.👉 Subscribe to Metabolic Mind for more conversations covering metabolic health, nutrition, food as medicine, and more.#MetabolicMind #FoodAsMedicine #DietaryGuidelines👉Do you have a question about ketogenic therapy or metabolic psychiatry? Submit your question to our team here: metabolicmind.org/questionsExpert Featured:Gary [email protected]://x.com/garytaubesDr. David [email protected]://x.com/davidludwigmdResources Mentioned:https://www.dietaryguidelines.gov/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can a ketogenic diet affect cardiovascular risk? Do nuts belong in a low-carb diet? What about ice cream, supplements, and electrolytes?In this episode of Metabolic Mailbag, Dr. Bret Scher tackles some of the most common and misunderstood questions about ketogenic therapy for metabolic and mental health. From concerns about LDL cholesterol to fears of liver and kidney damage, this conversation cuts through the noise with nuance, evidence, and practical guidance.This episode covers:LDL cholesterol spikes on a ketogenic diet: what’s normal, what’s not, and how to think beyond one lab numberStatins vs. individualized risk assessment (imaging, metabolic markers, trends over time)How nuts fit into a ketogenic diet and when they become a problemKetogenic diets and liver/kidney health: what human data actually shows“Good keto” vs. “bad keto” and the role of whole foodsSupplements, electrolytes, and when they’re truly neededSnacking, sweeteners, keto desserts, and staying in ketosisWhether you’re just starting a ketogenic diet or fine-tuning it for long-term metabolic or mental health, this episode offers clarity where confusion is common. By unpacking real-world questions with a clinical lens, Dr. Scher empowers you to think critically, personalize your approach, and make decisions rooted in human evidence—not fear or headlines.Do you have more questions? Check out our other Mailbag Q&A episodes with Dr. Bret Scher and Dr. Georgia Ede:Episode 1: https://youtu.be/PDgM-SD3Fx4Episode 2: https://youtu.be/3m6Fm0nXaMQEpisode 3: https://youtu.be/UgaaYl6RPbsEpisode 4: https://youtu.be/roMq4YU58rcEpisode 5: https://youtu.be/_eSVU5_P7YsEpisode 6: https://youtu.be/TcfGZ3m-lzE🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatry #QAExpert Featured:Dr. Bret Scherhttps://x.com/bschermdhttps://www.linkedin.com/in/bret-scher-08baaa102/Resources Mentioned:Understanding the Well-Formulated Ketogenic Diet https://www.metabolicmind.org/resources/library/blog/perspectives-in-metabolic-psychiatry/well-formulated-ketogenic-diet/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is carb-loading really the key to endurance and performance? A groundbreaking 100-page publication led by Dr. Andrew Koutnik says it’s time to question the dogma.For decades, athletes have been told that more carbs mean better performance. Strategies like carb-loading before and using sugary gels during exercise have become staples of endurance performance.But recent research has unveiled a shocking truth. Many athletes, even those who look healthy on the outside, are showing glucose levels consistent with prediabetes on the inside.In this interview, Dr. Bret Scher and Dr. Andrew Koutnik unpack the new landmark publication that challenges outdated sports nutrition guidelines and reveals another approach to fueling human performance.📌 What you’ll learn:How carb-loading is increasing the risk of prediabetes in fit, lean, athletesHow glycogen and carbohydrate intake have been mistaken as the primary predictors of performanceWhy maintaining stable blood glucose is the real key to performanceA new model for fueling that prioritizes brain energy and metabolic healthThis conversation is for athletes at every level, from elite competitors to everyday movers, and for anyone curious about how metabolism shapes performance, resilience, and long-term health.👉 Subscribe to Metabolic Mind to stay up-to-date on the latest in metabolic health, ketogenic therapy, and mental wellbeing: https://www.youtube.com/@metabolicmind.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.📨 Sign up for the Metabolic Mind Newsletter for the latest research, science, and tools for metabolic therapy at https://www.metabolicmind.org/about-us/newsletter/#MetabolicMind #KetogenicTherapy #SportsNutritionExpert Featured:Dr. Andrew KoutnikX.com/@AKoutnikinstagram.com/andrewkoutnikphdyoutube.com/andrewkoutnikphdwww.andrewkoutnik.comResources Mentioned:Carbohydrate Ingestion on Exercise Metabolism and Physical Performancehttps://doi.org/10.1210/endrev/bnaf038Coalition For Metabolic Healthcoalitionformetabolichealth.orgFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

In this special Metabolic Mailbag episode, cardiologist Dr. Bret Scher steps into the hot seat to answer your most pressing questions about ketogenic therapy, heart health, and metabolic markers. Drawing directly from listener questions, this conversation tackles the confusion and concern many people face when lab results change after starting a ketogenic diet.📌 In this video, you’ll learn:Why LDL may rise on a ketogenic diet and when that change is clinically meaningfulWhat cholesterol markers actually tell us about heart disease riskHow to think about hyper-responders and familial hypercholesterolemia (FH)How to interpret CRP and other inflammation markers in contextWhether you really need to track ketones and affordable ways to do itHow often to test labs like LDL, CRP, and other key markersThere’s a lot of confusion around ketogenic diets, cholesterol markers, and heart disease risk. In this episode, Dr. Scher debunks some of the most common myths and offers a clearer, more nuanced understanding of how ketogenic therapy can impact, and often improve, metabolic and cardiovascular health.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #Q&A #HeartHealthExpert Featured:Dr. Bret Scherhttps://x.com/bschermdhttps://www.linkedin.com/in/bret-scher-08baaa102/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

The science of metabolic psychiatry is advancing, but the movement behind it is just getting started. In this episode, Dr. Bret Scher sits down with Natasha Smikles and Eddie Rodriguez from Metabolic Collective, a new nonprofit working to build an international advocacy network for ketogenic and metabolic therapies.Their goal: accelerate awareness, adoption, and support for metabolic interventions in mental health.They cover:The personal journeys that led Natasha and Eddie to metabolic therapyWhy lived experience is such a powerful driver of changeWhy Metabolic Collective was created, and who it’s forHow Metabolic Collective is organizing community-led advocacy and educationWhat tools, resources, and events are available to help you get involvedHow to support others, start a local group, or bring metabolic psychiatry into your communityMetabolic psychiatry is growing, and movements like this are helping close the gap between research and real-world impact. From mental health challenges to neurological disorders, the Metabolic Collective hopes to spread the word about metabolic therapies and empower patients with alternative options to standard of care.👉Learn more about the Metabolic Collective at https://metaboliccollective.org. 👉Read the Metabolic Collective case for support at https://metaboliccollective.org/case-for-support/.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatry🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Experts Featured:Natasha [email protected]://www.instagram.com/natasha.smikles/https://x.com/NatashaSmikleshttps://www.linkedin.com/in/natasha-smikles-93753523a/Eddie Rodriguezhttps://www.instagram.com/brainheal_th_/?hl=enhttps://www.youtube.com/@BrainHeal_th_https://x.com/BrainHealth919Resources Mentioned:https://metaboliccollective.org/https://metaboliccollective.org/case-for-support/https://www.metabolicmind.org/thinksmart/https://www.facebook.com/groups/metaboliccollective/https://x.com/metcollectiveFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is caffeine sabotaging your mental health progress? Should you try a carnivore diet if keto isn't working? What if your meds lower ketones?In this new Metabolic Mailbag episode, Dr. Georgia Ede joins Dr. Bret Scher to answer your most pressing questions about metabolic therapies, mental health, and more.Together, they dive into nuanced, evidence-informed conversations about:The real impact of caffeine on mood, sleep, and ketosisWhether the carnivore diet is “too high” in proteinWhy some people see mental health improvements on carnivore when a ketogenic diet hasn’t workedWhat to do when medications interfere with ketone levels, and why deprescription must be done safely and strategicallyAnd moreMetabolic psychiatry is a promising frontier, and we’re here to empower individuals navigating serious mental illness with tools and knowledge rooted in science, compassion, and real-world experience.🔎Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.🔔 Subscribe to Metabolic Mind and join the growing community exploring metabolic therapies for mental health: https://www.youtube.com/@metabolicmind#MetabolicMind #KetogenicTherapy #FoodAsMedicine #QuestionAndAnswerExpert Featured:Dr. Bret Scherhttps://x.com/bschermd/https://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enResources Mentioned:Change Your Diet, Change Your Mind by Dr. Georgia Edehttps://www.amazon.com/Change-Your-Diet-Mind-Powerful/dp/1538739070 Taper Down Slowly: A Beginners Guide to Psychiatric Drug Tapering (Part 1)https://www.youtube.com/watch?v=RVMvi-vU5E8 Go Slowly: A Beginners Guide to Psychiatric Drug Tapering (Part 2) https://www.youtube.com/watch?v=rUdXDG8uKUY Keto and Psych Meds Topic Pagehttps://www.metabolicmind.org/resources/topics/keto-and-psych-meds/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Do SSRIs help your brain?SSRI medications are among the most widely prescribed antidepressants, but what if we’ve misunderstood how they work? In this interview, Dr. Bret Scher sits down with biochemist and nutrition scientist Dr. Chris Masterjohn to explore a deeper, more systemic view of mental health and how we treat it.Dr. Masterjohn reveals why serotonin isn’t just a “mood booster,” how SSRIs may be disrupting mitochondrial function, and why focusing on lifestyle strategies that support brain energy metabolism could unlock new paths for treating depression.🔍 What you’ll learn:Chris’s personal journey from veganism to carnivoreThe importance of testing for nutrient deficienciesHow mitochondria influence mood and cognitionWhy SSRIs may disrupt brain energy metabolismThe truth about serotonin and morning sunlightWhy exercise & nutrition often outperform medicationWhat SSRIs really do (and what they don’t)If you've ever questioned the serotonin theory of depression, or sensed there’s more to the story than what mainstream medicine tells us, this conversation fills in some of the missing pieces.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.👉 Subscribe to Metabolic Mind for more interviews, research, and updates in the field of metabolic psychiatry.Expert Featured:Dr. Chris Masterjohnhttps://www.chrismasterjohn-phd.com/https://substack.com/@chrismasterjohnphdhttps://x.com/ChrisMasterjohnhttps://www.facebook.com/chrismasterjohn/https://www.instagram.com/chrismasterjohn/Resources Mentioned:Substack: Prozac is a Performance Enhancing Drughttps://chrismasterjohnphd.substack.com/p/prozac-is-a-performance-enhancingMitome: Mitochondrial Analysishttps://www.mito.me/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is carb-cycling okay on a ketogenic diet? What about high histamine foods?In this episode of Metabolic Mailbag, Dr. Bret Scher and Dr. Georgia Ede answers questions on everything from the best sources of dietary fat to how to handle anxiety, perimenopause, and alcohol while maintaining ketosis.They unpack how to build a nutrient-dense, brain-supportive ketogenic diet using whole foods, why “keto-friendly” processed products can sometimes derail progress, and when supplements might be beneficial. You’ll also learn why histamine sensitivity, caffeine, or cycling in and out of ketosis can affect mood, and how to troubleshoot each.This conversation covers:Why a whole food ketogenic diet can be ideal for mental healthHow to identify the best fat sources and avoid “factory fats”Ketogenic dieting for women’s healthWhy anxiety can worsen mid-journey, and how to adaptThe truth about alcohol, carb cycling, and ketosisIf you’re exploring ketogenic therapy for mental or metabolic health, this episode offers practical, science-based guidance to help you refine and personalize your approach.🔎 Have questions about ketogenic diets or how to apply ketogenic therapy effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.👉Stay up to date with the latest, news, insights, and research on metabolic psychiatry by subscribing to Metabolic Mind: https://www.youtube.com/@metabolicmind#MetabolicMind #KetogenicTherapy #FoodAsMedicine #QuestionAndAnswerExpert Featured:Dr. Bret Scherhttps://x.com/bschermd/https://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enResources Mentioned:Dr. Bret Scher’s Carb Cycling Video: https://www.youtube.com/watch?v=b5bUc7TbS6oDr Madison Kackley: Keto for Women https://www.youtube.com/watch?v=IQ8aGNwGB9cFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

New research links chronic stress, brain energy, and psychiatric conditions, including PTSD, depression, and bipolar disorder.Stress doesn’t just impact your mood; it affects how your brain allocates energy. In this interview, Dr. Bret Scher sits down with Dr. Parker Kelly, a postdoctoral fellow at UCSF and the San Francisco VA, to unpack the Allostatic Triage Model of Psychopathology, a new framework proposing that psychiatric symptoms may emerge when the brain is forced to triage limited metabolic resources under chronic stress. Co-authored with mitochondrial researcher Dr. Martin Picard, this model could shift how we understand and treat mental illness.In this conversation, you’ll learn:How stress drives brain energy dysfunctionWhy mitochondria and metabolism may be central to mental illnessWhich brain networks are impacted by energy deficitsThe role of predictability and routine in stress resilienceHow metabolic therapies like nutrition, sleep, and even psychedelics, may support brain energy regulationThis conversation bridges neuroscience, metabolism, and mental health, offering a unique and unifying lens on complex psychiatric conditions.👉Subscribe to Metabolic Mind for more conversations about metabolic health, metabolic psychiatry, and mental health: https://www.youtube.com/@metabolicmind.#MetabolicMind #KetogenicTherapy #NeuroscienceExpert Featured:D. Parker KelleyX.com/sequencemyneurohttps://bsky.app/profile/sequencemyneuro.bsky.socialhttps://www.linkedin.com/in/dparkerkelleyphd/Resources Mentioned:The allostatic triage model of psychopathology (ATP Model): How reallocation of brain energetic resources under stress elicits psychiatric symptomshttps://doi.org/10.1016/j.neubiorev.2025.106419Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.