Permission With Shadia Akle

On this episode of Permission, Dr. Mary Pardee, a naturopathic and functional medicine doctor, reveals why years of protocols, supplements, and testing often leave patients feeling more stuck than ever before. After spending her own life struggling with unexplained gut issues, Dr. Pardee discovered that the "magic bullet" isn’t always physical.We dive deep into the science of the gut-brain axis and how the relentless pursuit of "health" through restriction and hyper-vigilance can actually amplify your physical symptoms. If you are a high-performer who feels like they are doing everything "right" but still can’t find relief, this conversation is for you.Key topics we discuss:The Gut-Brain Spiral: How paying more attention to a symptom tells your brain to amplify the pain.Maladaptive Behaviors: Why restrictive diets and constant "body checking" often make GI issues worse.The Price of Control: How rigidity and "Type A" perfectionism can prohibit the body from truly healing.Physiological Impact of Guilt: What happens inside a woman’s body when she eats with fear or restriction.Nervous System Safety: Why your body might be stuck in a fight-or-flight response despite your best efforts.Tools for Release: The science-backed benefits of diaphragmatic breathing and why crying is a powerful "biohack" for your nervous system.If you’ve been trying to fix yourself for years, it might be time to start listening instead.Connect with Dr. Mary Pardee:Website: modrnmed.comInstagram: @dr.marypardeeFollow the Podcast:Instagram → @spermission.podConnect with Shadia:🌐 shadiaakle.com📸 Instagram → @shadiaakle🎧 Listen on Spotify & Apple Podcasts → Permission with Shadia AkleIf this episode shifted something for you, leave a 5-star review and send it to someone who can benefit from it. That's how this work reaches the women it was made for.#permissionpodcast #biohackingtips #mentalhealth  #supplementscience #autoimmunehealing #nervoussystem #personaltransformation #consciousness #functionalmedicine #podcast #motivation #guthealth #gutmicrobiome #naturopathy #mindset 

This episode features a powerful conversation with Shawn Wells, a world-renowned biochemist and the man the industry calls the "World’s Greatest Formulator."Despite his massive professional success, Shawn’s personal journey began in a very different place, struggling with morbid obesity, chronic autoimmune diseases, and deep depression that led to frequent suicidal thoughts.In this vulnerable and science-backed discussion, Shawn reveals how he transformed his "rock bottom" into what he now calls a "bonus life." We bridge the gap between the lab and the soul to explore how your nervous system, your DNA, and even your sense of play dictate your health.Inside this episode, you’ll discover: -The Science of Generational Trauma: How up to 14 generations of trauma can be stored in your DNA and cells, and the protocol Shawn used to begin clearing it. -Why Your Supplements Might Not Be Working:The surprising reason your nervous system must be in "parasympathetic" mode to actually absorb and utilize nutrients.-The Truth About Depression: Why it isn't just a serotonin deficiency, but an "all-transmitter" shutdown designed to help your brain feel less pain. -Rewiring the Brain: How to turn off the "Default Mode Network" to silence the ego and rewrite the stories that keep you stuck in negative loops.-The Energy Revolution: Behind the scenes of Shawn’s creation of Paraxanthine, the natural caffeine alternative that boosts focus and GLP-1 without the "crash" or anxiety.-Boundaries as Self-Love: Why using your voice is a biological necessity for healing autoimmune disorders and reclaiming your power.If you are currently feeling broken or "begging yourself for permission" to live your life, this episode is your roadmap to starting over.Connect with Shawn Wells:Website: https://shawnwells.com/Instagram/Socials: @shawnwellshttps://www.instagram.com/shawnwells/ Bestselling Book: The Energy FormulaFollow the Podcast:Instagram → @spermission.podConnect with Shadia:🌐 shadiaakle.com📸 Instagram → @shadiaakle🎧 Listen on Spotify & Apple Podcasts → Permission with Shadia AkleIf this episode shifted something for you, leave a 5-star review and send it to someone who can benefit from it. That's how this work reaches the people it was made for.#permissionpodcast #biohackingtips #mentalhealth #shawnwells #supplementscience #autoimmunehealing #nervoussystem #personaltransformation #traumarecovery #glp1 #consciousness #functionalmedicine #podcast #motivation #

Your gut has been trying to tell you something. This is the episode where you finally listen.The bloating that started in your twenties.The exhaustion no amount of sleep touches.The anxiety that arrives before your thoughts do.The autoimmune diagnosis no one in your family has.What if none of it is random? What if it's not your hormones, your stress levels, or your imagination, and what if the answer has been sitting in a place modern medicine is only just beginning to understand?In this episode of Permission, I sit down with Dr. Sabine Hazan, MD, one of the most respected microbiome researchers in the world, for a conversation that quietly dismantles almost everything we've been told about women's health.She explains why your gut holds what your mind has tried to forget.Why the probiotics on your kitchen counter are likely lying to you. Why the same protocol that healed your friend may be silently harming you. And why the medical system's obsession with killing what's wrong has cost us the ability to restore what's right.This is the conversation I wish every woman had access to in her twenties. Some episodes inform you. This one returns something to you.About Dr. Sabine Hazan, MD Dr. Sabine Hazan is a board-certified gastroenterologist, microbiome researcher, and founder of ProgenaBiome, a genetic sequencing research lab pioneering the future of precision gut medicine. She is currently leading FDA-approved clinical trials on familial fecal transplants for children with autism and is widely regarded as one of the most important voices reshaping how the medical world understands the human microbiome.Inside this episode:→ Why your gut and your nervous system speak the same language, and why healing one without the other is why you keep ending up back at square one→ The "fingerprint" microbiome theory: why no single diet, probiotic, or protocol could ever work for every body→ The yogurt study that should have made headlines: Dr. Hazan tested 26 store-bought probiotic yogurts. Only 3 contained the bacteria on the label.→ The antibiotic crisis no one's talking about, and the rise of superbugs we created ourselves→ Why the modern woman's microbiome is collapsing under stress, and how it's quietly fueling the autoimmune epidemic→ The FDA-approved clinical trial using sibling stool transplants to help children with autism regain speech→ A future where your microbiome predicts Alzheimer's and Parkinson's decades before they appear→ The unglamorous, deeply ancient practices Dr. Hazan says heal the gut faster than any supplement on the shelf. Permission with Shadia Akle is a podcast for women unlearning every voice that wasn't theirs. New episodes weekly.Connect with Shadia:🌐 shadiaakle.com📸 Instagram → @shadiaakle🎧 Listen on Spotify & Apple Podcasts → Permission with Shadia AkleConnect with Dr. Sabine Hazan:🌐 progenabiome.com📸 Instagram → @sabinehazanmdIf this episode shifted something for you, leave a 5-star review and send it to a woman in your life. That's how this work reaches the women it was made for.

You are more microbe than human and your gut bacteria are deciding whether you heal or stay sick. Research microbiologist and gut health pioneer Kiran Krishnan breaks down the gut-brain connection, how childhood trauma lives in your microbiome, why a single course of antibiotics can wipe out 90% of your gut, and why no matter what your body has been through, repair is always possible.In this episode we cover: — The gut-brain axis and why your gut controls your mood, anxiety, and nervous system — How stress triggers fight-or-flight and destroys your microbiome from the inside — Childhood trauma and how it imprints on your gut bacteria for decades — The root cause behind PCOS, diabetes, lupus, and chronic inflammation — Why the people you live with are shaping your biology right now — The vaginal microbiome, declining fertility, and what no one is talking about — Why most probiotics don't work and what actually does — How to test your microbiome the right way — The oral microbiome and why your mouthwash might be making you sick🔗 Learn more about Kiran Krishnan's work: https://www.instagram.com/kiranbiome/Subscribe to Permission for new episodes every Tuesday.

By the time you're 40, your body has already lost a significant amount of the one molecule responsible for keeping your cells alive, energized, and repairing themselves. It's called NAD. Without it, you'd die in 30 seconds. And almost no one is talking about why it disappears, or what actually works to bring it back.I sat down with Dr. Nichola Conlon — molecular biologist, longevity scientist, and founder of Nuchido — and she didn't hold back. She walked me through what's really happening inside our cells as we age, why the decline hits women especially hard during perimenopause and menopause, and why some of the most popular anti-aging treatments on the market right now — including NAD IVs — could be triggering an inflammatory response instead of helping you.She also told me what she thinks actually works. And honestly, it's not what I expected to hear from someone with her background.We talk about why your skin is aging from the inside out and what that really means, the foundational habits she puts above every supplement and treatment, and the 12 hallmarks of aging that scientists now believe are driving chronic disease.And then something shifted in this conversation. A woman who's spent her career in drug development and cell biology tells me she's gone back to university, not for more science, but to study consciousness, metaphysics, and what psychedelics are revealing about the human mind. She talks about 37 trillion cells working together inside your body, why your gut feelings might be more intelligent than you give them credit for, and what happens when a scientist reaches the edge of what science can explain.This one stayed with me long after we stopped recording.CONNECT WITH DR. NICHOLA CONLON:🔬 Nuchido 📸 Instagram CONNECT WITH PERMISSION:📸 Instagram 🎙️ Spotify 🎙️ Apple Podcasts 🎙️Youtube🔔 Subscribe to Permission so you never miss an episode.

Welcome to Permission, a space for the conversations that ask us to come home to ourselves.For Episode 2, I sat down with Dr. Vincent Pedre, gut health expert and integrative medicine physician. We talk about what the body remembers, why our symptoms are rarely random, and how emotional trauma shapes the gut in ways most doctors miss.In this conversation:The connection between heartbreak, loss, and physical illness like SIBO and bloating.Why trapped memories and unprocessed grief live in the body.The placebo effect as real clinical medicine.Vincent's own story of gut issues starting at age ten.A teenage patient who reversed her autoimmune diagnosis through gut healing.Energetic boundaries and how to protect your vitality.The Zen mindset shift that changes how we move through the world.For the woman ready to listen to what her body has been saying.Follow @permission.pod and @shadiaakle on Instagram.Connect with Dr. Vincent Pedre:Instagram: @drpedreBooks: Happy Gut and The GutSMART Protocol (available on Amazon)Take his free 2-minute gut quiz at happygutlife.comWork with Dr. Pedre at pedremd.com

Welcome to Permission, a space for the conversations that ask us to come home to ourselves.For the first episode, I sat down with Annalie Howling, author of Unapologetic and a trauma specialist. We talk about shame, self-abandonment, and what it actually means to come home to ourselves.In this conversation:Why shame is a liar.The difference between guilt and shame.The inner critic as the custodian of your comfort zone.Fawning and why it carries the most shame of all trauma responses.Pleasure as self-responsibility.Self-compassion as the cure.For the woman ready to stop carrying what was never hers to carry.Follow @permission.pod and @shadiaakle on Instagram.Annalie's book Unapologetic is available on Amazon.

Welcome to Permission with Shadia Akle. Here's what nobody talks about in wellness: you can do everything right and still not feel right. The supplements, the protocols, the labs, the clean eating, and your body is still asking for something none of it can give.Your body isn't broken. It never was. It's been carrying what you couldn't. The job that drained you. The relationship that shrank you. The version of yourself you kept performing because somewhere, quietly, you were taught your needs would have to wait.No supplement in the world can speak louder than a life that needs you to finally listen.Every week, I sit down with brilliant doctors, scientists, researchers, and healers, and together we talk about the part most health conversations leave out. Not just what's happening in your body — but why. The science and the story behind it. The biology and what it's been holding for you. The conversation your symptoms have been trying to start.I don't come here as the woman with all the answers. I come as someone who has been in the question, is still in the question, and has picked up enough along the way to want to share it.This is for the woman who has done everything “right” and is tired of pretending that's enough. Who senses her body is trying to tell her something her labs can't explain. Who is done waiting for the right time to come home to herself.You don't need another protocol. You need permission.Permission to rest. Permission to listen. Permission to stop waiting and start becoming.Welcome to Permission. Your body's been waiting for this conversation.Youtube: https://www.youtube.com/@shadiaakleInstagram: https://www.instagram.com/permission.podhttps://www.instagram.com/shadiaakleTikTok: https://www.tiktok.com/@permission.podLinkedIn: https://www.linkedin.com/in/shadia-akle