PODCAST · health
SetSet with April Pride
by SetSet
SetSet supports women exploring psychedelics, cannabis, and hemp. This show is intended for anyone seeking transformation with the assistance of psychoactive substances. If you're looking to "trip" with friends or "journey" with a trained facilitator, SetSet offers practical, seasoned insights to help you optimize the potential of your next experience. Host April Pride shares expert knowledge, anecdotal stories, and data-backed resources for listeners, including as they integrate their insights and discoveries from expanded consciousness.
Episodes
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135. A Medical Doctor Gives His Opinion on Psychedelics and Grief
Can psychedelics help with grief? This is what we explore in the audience Q&A from Psychedelic Salon on grief, recorded live at Town Hall Seattle with Dr. Sunil Aggarwal. It picks up where last week's main conversation left off, and the questions that night ranged far wider than a single loss:...
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134. Can Psychedelics Help With Grief?
This episode is about psychedelics and grief, and it starts from an unusual place: not death, but everything else grief actually is. Loss of a future you thought you had. Loss of an identity, a marriage, a body that no longer works the way it used to. That's the frame Dr. Sunil Aggarwal and I set...
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133. Psilocybin and Seniors: Cost, Potency, and What to Do When Nothing Happens
133. What If Nothing Happened During Your Trip? Someone in the room had done everything right. Careful preparation, a trained guide, two booster doses of psilocybin. Nothing happened. No altered state. In this episode, learn what that means and what to do next.This is the audience Q&A from the...
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132. The Acid Queen, Rosemary Woodruff Leary: An LSD Muse and Fugitive
Rosemary Woodruff Leary sat in a jail cell for a month rather than testify against her husband. While she was inside, Timothy Leary gave a ten page interview to Playboy about what LSD does to a woman's body and did not mention her once. She was his editor, his translator, the person who read the...
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131. Can psilocybin help with menopause?
131. Can psilocybin help with menopause? A live audience of 300 at Town Hall Seattle asked Dr. Trish Singh and Kelly McGinty, C-FNP, co-authors of Mycelopause: Uncovering the Magic of Menopause with Psilocybin, the questions that don't come up in a doctor's office: whether psilocybin is safe…
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130. Psilocybin and Perimenopause: Two Clinicians Reframe Midlife for Women
130. Psilocybin and Menopause: Two Clinicians Reframe Midlife for Women Episode Summary Estrogen regulates the serotonin system, and psilocybin reaches the same receptor. That is where this Salon starts, and it is the most specific version of the psilocybin and menopause conversation I have heard...
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129. Psychedelics for Seniors: Aging, Grief, and Meaning Making
129. Psychedelics for Seniors: Aging & What's Next Episode Summary The psychedelic renaissance gets covered like a young person's story: executives microdosing before board meetings, twenty-somethings on retreats. But the fastest-growing population interested in this medicine right now is...
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128. Ancestral Trauma, IFS, and the Real Work of Psychedelic Integration
128. Ancestral Trauma & Psychedelic Integration A 45-year psychedelic guide on ancestral trauma, Internal Family Systems, and why integration, not the ceremony, is the real medicine. Episode Summary Most conversations about psychedelics stay at the level of the ceremony: the dose, the visions…
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127. Psilocybin and Anorexia: The First New Idea in Decades
127. Psilocybin for Anorexia: Inside UCSF's Trial Dr. Amanda Downey on UCSF's psilocybin trial for anorexia, why caregivers enroll, and what the medicine can and can't reach in eating disorders. Episode Summary Eating disorders are the deadliest psychiatric illness we have. Someone in the United...
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126. Psychedelics & Addiction: What the Research Actually Says
126. Psychedelics & Addiction: What the Research Shows Addiction psychiatrist Dr. Nathan Sackett on psilocybin, ibogaine, MDMA, ketamine, and what psychedelic-assisted therapy can and cannot do for substance use disorder. Episode Summary The conversation about psychedelics as addiction treatment…
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125. What Women's Hormones, Cycles, and Lived Experience Have to Teach Psychedelic Medicine
125. The Wise Body: What Women's Hormones, Cycles, and Lived Experience Have to Teach Psychedelic Medicine Stephanie Karzon Abrams of Galilea on why psychedelic care must account for women's cycles, life stage, and the knowledge that predates clinical trials. Episode Summary The research on...
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124. Psychedelic Integration and Intuition: What Actually Changes After Ayahuasca
124. Psychedelic Integration and Intuition: What Actually Changes After Ayahuasca Explore psychedelic integration and intuition through ayahuasca, grief, and leadership. What really changes after plant medicine? Episode Summary What actually happens after the ceremony ends? In this episode, April...
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123. Microdosing for Midlife — Week 6: Emotional Resilience and Rewriting Old Patterns
123. Microdosing for Midlife: Emotional Resilience(Week 6) Week 6 explores extinction learning, emotional resilience, and how microdosing may support gradual rewiring of fear-based patterns in midlife. Episode Summary This episode is part Week 6 of Microdosing for Midlife—a 12-part audio…
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122. Microdosing for Midlife — Week 5: Mask Off — Authenticity for Real
122. Microdosing for Midlife: Stability & Nervous System Change (Week 5) Week 5 explores masking, authenticity, the Default Mode Network, and how microdosing may soften rigid self-narratives in midlife. Episode Summary This episode is part Week 5 of Microdosing for Midlife—a 12-part audio…
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121. Microdosing for Midlife — Week 4: Stability, Change, and the Nervous System
121. Microdosing for Midlife: Stability & Nervous System Change (Week 4) Week 4 of Microdosing for Midlife explores how nervous system stability shapes identity, growth, and long-term change in midlife. Episode Summary This episode is part Week 4 of Microdosing for Midlife—a 12-part audio…
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120. Microdosing for Midlife, Week 3: Hormones, Perception, and Libido in Menopause
120. Microdosing for Midlife: Hormones, Perception, and Libido (Week 3) Exploring how menopause, perception shifts, and nervous system regulation intersect with midlife libido. Episode Summary This episode continues Week 3 of Microdosing for Midlife, April Pride’s 12-part audio companion to her...
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119. Microdosing for Midlife, Week 2: Brain Science of Change
119. Microdosing for Midlife: Brain Science of Change (Week 2) Week 2 of Microdosing for Midlife explores estrogen, menopause, hormone therapy, and cognitive health—plus how psilocybin supports neuroplasticity. Episode Summary This episode marks Week 2 of Microdosing for Midlife, a 12-week audio...
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118. Microdosing for Midlife, Week 1: Intention & Dosage
118. Microdosing for Midlife: Intention Setting, Integration, and Finding Your Dose (Week 1) Week 1 of Microdosing for Midlife explores intention setting, finding the right microdose, and integrating psilocybin gently during midlife transitions. Episode Summary This episode marks Week 1 of...
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117. Ibogaine Therapy Safety & Ethics: What Responsible Care Really Looks Like
117. Ibogaine Therapy Safety & Ethics: What Responsible Care Really Looks Like A grounded conversation on ibogaine therapy safety and ethics—covering medical oversight, risks, integration, and responsible psychedelic care. Episode Summary Ibogaine is often described as a breakthrough for…
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116. Psychedelics and Aging: Meaning, Grief, and Integration in Later Life
116. Psychedelics and Aging: Meaning in Later Life An educational conversation on psychedelics and aging, exploring meaning-making, grief, safety, and integration through lived experience and research. Episode Summary What happens when psychedelic experiences arrive later in life—after careers,...
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115. The 5-MeO-DMT Experience: Nervous System Surrender, Safety, and the God Molecule
115. 5-MeO-DMT Experience Explained A grounded conversation on the 5-MeO-DMT experience—how it affects the nervous system, how it differs from DMT, and why safety and integration matter. Episode Summary What is 5-MeO-DMT, and why do people describe it so differently from other psychedelics? In…
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114. Why & How to Start Microdosing: The Gentle Revolution
114. How to Start Microdosing with Psilocybin A science-backed guide to microdosing psychedelics with SetSet’s 12-week protocol, featuring expert insight and lived experience. Episode Summary If you’ve been microdose-curious — or maybe you’re already experimenting and want a little more structure…
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113. Psychedelic Law in Seattle: What’s Actually Legal in 2025?
113. Psychedelic Law in Seattle: What’s Actually Legal in 2025? SetSet Salon breaks down psychedelic law in Seattle with attorneys Perry Salzhauer & Daniel Shortt—what the entheogen resolution covers, what it doesn’t, and the risks it creates. Episode Summary Most people think Seattle has…
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112. Epidemic of Fear: How Psychedelics Help Us Get Unstuck
112. Epidemic of Fear: How Psychedelics Help Us Transcend Stuckness Discover how psychedelics help retrain the nervous system to move from fear to flow. April Pride explores the roots of stuckness, the Hero’s Journey, and how microdosing and macrodosing support nervous system healing. 🔵 What...
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111. MDMA vs. Kanna Trip Report, Molly's Effect on Sleep, and Bufo! with Andrew Weisse of The Psychedelic Blog
111. Trip Report: Kanna vs. MDMA Plus How Molly Effs With Your Sleep For Weeks What if you could feel more connected, relaxed, and joyful—without alcohol or MDMA? In this episode, I talk to Andrew Weisse, founder of getKanna and writer of Substack's The Psychedelic Blog, about the mood-enhancing,...
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110. Can Psilocybin Help You Drink Less?
110. How to Rethink Drinking Without "Hitting Rock Bottom" What if your relationship with alcohol doesn’t require a dramatic rock-bottom moment to change? In this episode of SetSet, I sit down with sobriety coach Martha Wright, who went from building a life around wine—professionally and...
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Book Club: Listening to Ecstasy with Charley Wininger (Recorded Live)
How MDMA Is Transforming Love, Aging & Grief Many people think MDMA is a party drug. What if it’s actually a medicine for seniors? Episode 111 of the SetSet Podcast. Join us for this deeply personal, science-backed live recording of our August virtual Psychedelic Salon. I was joined by Charley...
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109. How Psilocybin Microdosing Supports Menopause: A Brain-Based Guide
109. How Psilocybin Microdosing Supports Menopause: A Brain-Based Guide How can women navigate the emotional, cognitive, and hormonal rollercoaster of perimenopause and menopause? In this episode, April Pride explores how psilocybin microdosing may offer real support for women in midlife. From...
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Ep. 108 | Modern Bong Design for Women Who Smoke
108. Why Bong Design Matters for Modern Women: Esther Ramirez from Session Goods What if your bong could live on your coffee table—without shame or splashback? In this 4/20 Easter special, April Pride sits down with Esther Lenore Ramirez, co-founder and CEO of Session Goods, to explore how...
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Ep. 107 | Psilocybin for Menstrual Cycles and Menopause: A Women’s Wellness Protocol
107. Psilocybin for Menstrual Cycles and Menopause: A Women’s Wellness Protocol How can mushrooms sync with your cycle—or shift your experience of menopause? In this episode, April Pride is joined by Jennifer Chesak, author of The Psilocybin Handbook for Women, to decode the powerful relationship...
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Ep. 106 | Natural Psychedelics for Trauma Healing
106. Natural Psychedelics and the Healing Power of Community What if the most potent medicine isn’t just the mushroom or the ceremony—but the community that holds you through it? In this soul-stirring conversation, host April Pride continues her dialogue with healer and teacher Satya on the role…
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Ep. 105 | Science Meets Spirit in Psychedelic Healing
105. Integrating Science and Spirituality: A New Framework for Psychedelic Healing What does it mean to truly heal in a psychedelic space? In this episode, host April Pride is joined by Satya—a seasoned facilitator whose work bridges psychotherapy, meditation, and natural psychedelic therapy....
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Ep. 104 | Microdosing for Women: Habit and Hormone Healing
104. How Microdosing for Women Rewires Habit, Hormone, and Healing Cycles How does a microdose change a life? In this powerful conversation, April Pride returns with part two of her interview with guide Sand Symes to unpack what really happens when women begin a psychedelic microdosing protocol....
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Ep. 103 | Feminine Energy Healing with Psychedelics
103. Feminine Psychedelic Power: Healing Stories from the Inside Out In this soulful and story-rich episode, April Pride welcomes Sand Symes, a guide with decades of experience guiding women through psychedelic journeys. Together, they explore how feminine energy—when supported by plant medicine...
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Ep. 102 | At-Home Ketamine for Women: What to Know
102. Is At-Home Ketamine Treatment Safe for Women with Trauma? In this powerful second conversation with author and mental health advocate Kaia Roman, host April Pride explores the clinical, emotional, and cultural dimensions of at-home ketamine treatment—particularly for women navigating trauma,...
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Ep. 101 | Ketamine for Emotional Healing and Divorce
101. Ketamine for Emotional Healing: Divorce, Depression, and Dosing with Kaia Roman What happens when your life falls apart—and a new path reveals itself through ketamine-assisted therapy? In this vulnerable and science-savvy episode, April Pride talks with Kaia Roman, author of The Joy Plan,...
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Ep. 100 | Psychedelic Therapy for Women: 100 Episodes In
100. 100 Episodes In: What We’ve Learned About Psychedelic Therapy for Women This milestone episode is a love letter to our listeners. April Pride marks 100 episodes of SetSet by reflecting on what’s changed—and what still needs changing—in the conversation around psychedelic therapy for women....
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Ep. 99 | Ketamine Therapy for Women’s Mental Health
99. Ketamine Therapy for Women: Healing Trauma and Depression at Home How does healing begin when traditional mental health tools fall short? In this episode, April Pride continues her conversation with Jennifer Whetzel—branding expert, researcher, and founder of the Women in Cannabis Study....
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Ep. 98 | At-Home Ketamine Therapy for Trauma
98. At-Home Ketamine Therapy for Trauma: Jennifer Whetzel on Healing from the Inside Out What happens when traditional therapies stop working, but the healing isn’t done yet? In this episode, April Pride talks with Jennifer Whetzel—cannabis branding expert and creator of the Women in Cannabis...
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Ep. 97 | Psychedelic Healing Through Photography
97. From Tour Buses to Trauma Work: Rachel Demy on Psychedelic Healing Photography What happens when a touring photographer turns the camera inward? In this episode, April Pride sits down with Rachel Demy—longtime Death Cab for Cutie crew member turned fine art photographer—to explore how...
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Ep. 96 | Functional Mushroom Coffee for Mood and Brain Health
96. Why Functional Mushroom Coffee Might Be the Future of Wellness Curious about the magic behind mushroom coffee? In this episode, we’re sharing a feed drop from the Mush Love Podcast hosted by Tim Keck, featuring Wonderground founder Jody Hall. From Cupcake Royale to cannabis edibles to…
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Ep. 95 | Psilocybin Product Safety: What You Need to Know
95. What’s Really in Your Mushroom Bar? The Truth About Psilocybin Product Safety What if your “mushroom chocolate” has no mushrooms at all? In this eye-opening episode, April Pride continues her conversation with Joe Robinson, founder of PsiloSafe, to unpack the chaotic world of unregulated...
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Ep. 94 | Psilocybin Harm Reduction with PsiloSafe
94. Can We Trust Psychedelics? Inside PsiloSafe’s Mission to Keep You Safe How do we reduce harm as psychedelics move from sacred circles to Shopify carts? In this eye-opening episode, April Pride is joined by Joe Robinson, founder of PsiloSafe—a self-regulating initiative working to bring...
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Ep. 93 | Life Clarity Practice and Microdosing Guide
93. Life Clarity Practice and Microdosing: The Self-Inquiry Ritual You Didn’t Know You Needed How do we actually begin again—when the road ahead feels foggy, when our energy’s off, or we just feel like we’ve lost ourselves in the grind? In this episode, April Pride welcomes creative strategist…
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Ep. 92 | Amanita Muscaria for Anxiety and Focus: Beyond the Trip
92. Amanita Muscaria for Anxiety and Focus: Beyond the Trip In this second half of her conversation with Christian Rasmussen, host April Pride explores the broader applications of Amanita muscaria beyond addiction recovery. Christian shares real-world stories from his customers, tips for safe...
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Ep. 91 | Amanita Muscaria and Addiction Recovery: One Man’s Path Off Benzos
91. Amanita Muscaria and Addiction Recovery: One Man’s Path Off Benzos In this episode, host April Pride talks with Christian Rasmussen, founder of MN Nice Ethnobotanicals and the largest Amanita muscaria merchant in the U.S. Christian shares his powerful story of overcoming addiction to opiates...
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Ep. 90 | Therapeutic Microdosing with Amy Wong
90. Therapeutic Microdosing for Emotional Clarity and Identity Healing In this conversation between April Pride and Amy Wong Hope, we dive into the therapeutic power of microdosing psilocybin—not as a productivity hack, but as a personal practice to gently unravel conditioned identities and…
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Ep. 89 | MDMA-Assisted Healing and Psychedelic Therapy
89. MDMA-Assisted Healing & the Psychedelic Shift: A Therapist’s Take What happens when the FDA says no to MDMA therapy—but the healing continues anyway? In this two-part conversation, April Pride sits down with Amy Wong Hope, a licensed social worker and MAPS-trained MDMA-assisted therapy...
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Ep. 88 | Psilocybin Integration Cards for Connection
88. Set and Setting in a Box: How Psilocybin Integration Cards Spark Real Connection In this episode, April Pride invites listeners into her Seattle high-rise past for a raw, unscripted session with the psilocybin integration cards. You’ll meet Summer, a first-time participant, and Tilson, the...
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Ep. 87 | High Tech Weed for Modern Smokers
87. High Tech Weed & Design-Forward Devices: Reimagining the Ritual What happens when cannabis goes digital—and women lead the conversation? In this design-forward episode, April Pride continues her conversation with writer Clare Sausen of High Design, diving into how tech meets tradition in...
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ABOUT THIS SHOW
SetSet supports women exploring psychedelics, cannabis, and hemp. This show is intended for anyone seeking transformation with the assistance of psychoactive substances. If you're looking to "trip" with friends or "journey" with a trained facilitator, SetSet offers practical, seasoned insights to help you optimize the potential of your next experience. Host April Pride shares expert knowledge, anecdotal stories, and data-backed resources for listeners, including as they integrate their insights and discoveries from expanded consciousness.
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Frequently Asked Questions
How many episodes does SetSet with April Pride have?
SetSet with April Pride currently has 115 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is SetSet with April Pride about?
SetSet supports women exploring psychedelics, cannabis, and hemp. This show is intended for anyone seeking transformation with the assistance of psychoactive substances. If you're looking to "trip" with friends or "journey" with a trained facilitator, SetSet offers practical, seasoned insights to...
How often does SetSet with April Pride release new episodes?
SetSet with April Pride publishes regularly with 115 episodes available. Check the episode list for the typical release schedule.
Where can I listen to SetSet with April Pride?
You can listen to SetSet with April Pride on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts SetSet with April Pride?
SetSet with April Pride is created and hosted by SetSet.
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