SetSet with April Pride

124. Psychedelic Integration and Intuition: What Actually Changes After AyahuascaExplore psychedelic integration and intuition through ayahuasca, grief, and leadership. What really changes after plant medicine?Episode SummaryWhat actually happens after the ceremony ends? In this episode, April sits down with Lizzi Cutler to explore psychedelic integration and intuition beyond the peak experience. From ayahuasca integration to 5-MeO-DMT, Lizzi shares how plant medicine didn’t “fix” her—but instead revealed who she already was. The conversation moves through grief and identity, including the emotional reality of not becoming a mother, and expands into how intuition can be applied in unexpected places like business and leadership. This episode will help you understand how to integrate psychedelic experiences into daily life, trust your intuition, and rethink personal growth as an ongoing, nonlinear process.🔵 Key TakeawaysPsychedelics don’t fix you—they reveal patterns you’re already living insideTrue ayahuasca integration happens over years, not days or weeksIntuition isn’t mystical—it’s a skill that can be applied to leadership and hiringGrief and identity are deeply intertwined, especially around missed life pathsIntuitive leadership may be the missing link in building aligned teams and cultures🔵 Timestamps[00:00] Intro, disclaimer, and April’s context on consciousness + intuition[01:00] Introducing Lizzi Cutler and the theme of integration[02:00] Psychedelics and grief + upcoming salon context[03:00] Lizzi’s early work: yoga, meditation, and intuitive sensing[04:00] Naming subconscious patterns and how change begins[05:00] April’s narration: awareness, observation, and the double slit experiment[06:00] Applying intuition to business, hiring, and leadership[08:00] First ayahuasca invitation and entering ceremony work[09:00] Ayahuasca + San Pedro explained (context + risks)[10:00] First ceremonies: “feeling nothing” and frustration[10:30] Dieta explained: preparation, digestion, and intuition[12:00] First breakthrough experience and community bonding[13:00] Divorce, feeling “broken,” and seeking transformation[14:00] 30–40 ceremonies later: what ayahuasca actually revealed[15:00] “Own your power” and letting go of imitation[16:00] The apprenticeship dynamic + April’s ethical commentary[18:00] Surrendering to intuition and first real validation[19:00] Bringing intuitive work into real-world practice[20:00] Shifting from personal coaching to stress + behavior change[21:00] Breakthrough moment: intuition applied to business[22:00] Alignment, investing, and intuitive due diligence[23:00] Oneness, source, and early 5-MeO insights[24:00] Psychedelics don’t give gifts—they reveal them[25:00] Intuition as a natural ability vs learned skill[26:00] 5-MeO-DMT explained + non-dual awareness[26:30] “I am enough”: the end of the “I’m broken” narrative[27:00] Embodiment, love, and kintsugi (wholeness through integration)[28:00] Integration over time + relationships and emotional growth[29:00] Building an intuitive business model (CEO-focused work)[30:00] “Intuitive analysis” and reading organizational culture[31:00] AI vs intuition: human pattern recognition[32:00] Leadership decisions, restructuring, and team alignment[33:00] Working with investors, philanthropy, and impact[34:00] Money as energy + alignment in giving[35:00] Closing reflections + where this work is going[36:00] Outro + resources + psychedelic grief salon🔵 ResourcesMicro-Psyched 12-Week Microdosing ProgramWomen in the Wild gatherings - Reserve your spot in SeattleUpcoming Psychedelic Salon ticketsFollow April on SubstackOriginal Microdosing for Midlife Substack post: https://aprilpride.substack.com/p/psychedelic-integration-and-intuition-ayahuasca-leadershipHosted by April Pride @aprilpride_Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

123. Microdosing for Midlife: Emotional Resilience(Week 6)Week 6 explores extinction learning, emotional resilience, and how microdosing may support gradual rewiring of fear-based patterns in midlife.Episode SummaryThis episode is part Week 6 of Microdosing for Midlife—a 12-part audio companion to the original Substack series.In this conversation, April explores emotional resilience not as toughness or avoidance, but as the ability to update old responses in real time. Using entrepreneurship as metaphor, she reflects on how repeated attempts, setbacks, and recalibration build resilience—and how microdosing psilocybin intersects with that process.The episode introduces the neuroscience concept of extinction learning—the brain’s ability to replace outdated fear responses with more informed ones. Rather than positioning microdosing as a cure or shortcut, April frames it as a catalyst for noticing habitual reactions, pausing before reenactment, and building new neural pathways through integration.If the written post focused on the science and story, this episode explores how resilience is practiced—not performed—especially in midlife when old coping strategies no longer serve.🔵 Key TakeawaysWhat extinction learning means in practical termsHow emotional resilience differs from emotional suppressionWhy microdosing is described as a catalyst—not a quick fixThe role of integration in reinforcing new neural pathwaysHow midlife transitions resurface habitual responsesWhy subtle shifts often matter more than dramatic breakthroughsOne reflection to carry into the week ahead🔵 Timestamps[00:00] Episode opening[02:00] Entrepreneurship and resilience as metaphor[04:30] Extinction learning explained[07:00] Personal example of breaking habitual responses[10:00] Integration and grounding practices[13:00] Midlife transitions and emotional awareness[16:00] What to carry forward🔵 ResourcesMicro-Psyched 12-Week Microdosing ProgramWomen in the Wild gatherings - Reserve your spot in SeattleUpcoming Psychedelic Salon ticketsFollow April on SubstackOriginal Microdosing for Midlife Substack post: https://aprilpride.substack.com/p/microdosing-psilocybin-for-emotional-resilienceHosted by April Pride @aprilpride_Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

122. Microdosing for Midlife: Stability & Nervous System Change (Week 5)Week 5 explores masking, authenticity, the Default Mode Network, and how microdosing may soften rigid self-narratives in midlife.Episode SummaryThis episode is part Week 5 of Microdosing for Midlife—a 12-part audio companion to the original Substack series.In this conversation, April explores authenticity not as a dramatic revelation, but as a gradual unmasking. Rather than chasing peak experiences or forced breakthroughs, she reflects on how microdosing intersects with identity, ego softening, and the quiet recognition of truths long postponed. The episode examines the difference between escape and exposure—and why midlife often demands something more sustainable than either.Drawing from neuroscience, lived experience, and even a bridge to quantum physics, April considers how the Default Mode Network (DMN) reinforces self-stories—and how gentle disruptions may create space for new ones. This is not about dramatic ego dissolution. It’s about noticing the yes that’s actually a no, the roles we’ve outgrown, and the parts of ourselves we’ve hidden to stay acceptable.If you’ve read the original essay, this episode deepens it. If you haven’t, it stands on its own—and may send you back to read more closely.🔵 Key TakeawaysHow “masking” functions psychologically and neurologicallyThe role of the Default Mode Network in identity and self-storyWhy escape and authenticity are often confusedHow microdosing may soften rigid self-narrativesThe difference between forced revelation and sustained alignmentWhat flow actually represents in midlife transitionOne reflection to carry into the week ahead🔵 Timestamps[00:00] Episode opening[02:00] Masking, escape, and authenticity[05:00] A personal mask-off moment[07:00] Default Mode Network and ego narratives[10:00] Observation and identity[13:00] Flow and sustained alignment[15:00] What to carry forward🔵 ResourcesMicro-Psyched 12-Week Microdosing ProgramUpcoming Psychedelic Salon ticketsFollow April on SubstackOriginal Microdosing for Midlife Substack post: https://aprilpride.substack.com/p/microdosing-for-authenticityHosted by April Pride @aprilpride_Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

121. Microdosing for Midlife: Stability & Nervous System Change (Week 4)Week 4 of Microdosing for Midlife explores how nervous system stability shapes identity, growth, and long-term change in midlife.Episode SummaryThis episode is part Week 4 of Microdosing for Midlife—a 12-part audio companion to the original Substack series.In this conversation, April expands on what it actually means to feel stable while undergoing change. Midlife often brings visible transitions—shifts in hormones, identity, relationships, ambition—but underneath those external markers is something quieter: the nervous system recalibrating itself. Rather than focusing on dramatic breakthroughs, this episode examines how safety, steadiness, and subtle internal shifts create sustainable growth.Instead of chasing intensity, April reflects on how microdosing can support capacity—capacity to tolerate discomfort, to remain present in uncertainty, and to integrate insight gradually. The real work is not in peak moments. It’s in the ability to return to baseline without abandoning yourself.🔵 Key TakeawaysHow nervous system stability shapes long-term growth in midlifeWhy intensity is often mistaken for progressHow subtle shifts accumulate into meaningful identity changeWhat “capacity building” looks like beyond insightA reflection question to carry into the week ahead🔵 Timestamps[00:00] Episode opening[02:00] Framing the week’s theme[08:30] Nervous system stability vs intensity[15:00] Capacity building in midlife[22:00] Integration reflection[27:00] What to carry forward🔵 ResourcesMicro-Psyched 12-Week Microdosing ProgramUpcoming Psychedelic Salon ticketsFollow April on SubstackOriginal Microdosing for Midlife Substack post:https://aprilpride.substack.com/p/vagus-nerve-menopause-psilocybin-intuition-body-trustHosted by April Pride @aprilpride_ Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

120. Microdosing for Midlife: Hormones, Perception, and Libido (Week 3)Exploring how menopause, perception shifts, and nervous system regulation intersect with midlife libido.Episode SummaryThis episode continues Week 3 of Microdosing for Midlife, April Pride’s 12-part audio companion to her Substack series exploring microdosing through the lens of midlife transition.In this conversation, April examines one of the most quietly asked questions among women in perimenopause and menopause: can microdosing influence hormones or libido? Rather than positioning psilocybin as a hormonal intervention, she reframes the inquiry around perception, serotonin signaling, emotional regulation, and nervous system safety.The episode explores how estrogen fluctuations affect mood stability, why cortisol and stress patterns shape desire, and how subtle perceptual shifts—rather than dramatic sensations—may influence connection and intimacy. Through personal reflection and grounded science, April centers integration over hype.🔵 Key Takeaways• Sub-perceptual microdosing is about perception shifts, not noticeable psychedelic effects• Estrogen plays a role in serotonin regulation and emotional stability• Hormonal fluctuations in midlife can increase anxiety and mood vulnerability• Libido is influenced by stress regulation and psychological safety• Psilocybin research currently focuses on emotional systems—not hormone “balancing”• Interoception (body awareness) may shift during midlife transitions• Structured integration matters more than isolated insight🔵 Timestamps[00:00] Episode disclaimer and introduction[01:00] The neurobiology of change and structured microdosing[02:00] Sensation vs. perception in microdosing[04:00] Rewriting grief narratives and identity shifts[05:00] Estrogen, serotonin, and cortisol interactions[06:30] Oxytocin, connection, and emotional openness[08:00] Interoception and body awareness[09:00] Libido and menopause[10:00] Emotional safety and renewed desire[11:00] Closing reflections🔵 Additional ResourcesMicro-Psyched Microdosing GuideOriginal Week 3 post on SubstackWomen in the Wild - Reserve your spot!Learn more about this episode: https://aprilpride.substack.com/p/microdosing-for-midlife-week-3-hormones-libidoHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

119. Microdosing for Midlife: Brain Science of Change (Week 2)Week 2 of Microdosing for Midlife explores estrogen, menopause, hormone therapy, and cognitive health—plus how psilocybin supports neuroplasticity.Episode SummaryThis episode marks Week 2 of Microdosing for Midlife, a 12-week audio series exploring how psilocybin microdosing for women intersects with hormonal change, emotional regulation, and cognitive resilience during midlife.In this installment, April Pride expands on a central question that surfaced after Week 1: whether being “spared” classic menopausal symptoms—or choosing not to take hormone replacement therapy—puts women at greater risk for cognitive decline. Drawing from current research, April reframes the fear-driven narrative around menopause, estrogen, and dementia, offering a more nuanced and reassuring understanding of what actually shapes long-term brain health.The episode also explores estrogen’s role as a neuroprotectant, how the midlife brain becomes more vulnerable to stress-based patterning, and why psychedelics like psilocybin may support neuroplasticity by softening rigid survival scripts. Through personal reflection and lived experience, April illustrates how subtle shifts in perception—not emotional erasure—can change one’s relationship to anxiety, grief, and uncertainty.This episode functions as an audio companion to the written Week 2 essay, adding scientific context, integration insights, and real-life application without replacing the original post.🔵 Key Takeaways• Menopause as a neurological transition, not just a hormonal one• Estrogen’s role in cognition, mood, and neuroprotection• Why high symptom burden—not absence of symptoms—is linked to later cognitive risk• What hormone therapy does and does not do for long-term cognition• The default mode network and midlife rumination patterns• Psychedelics, neuroplasticity, and loosening fear-based survival scripts• Microdosing as a tool for integration rather than emotional suppression🔵 Timestamps[00:00] Reflections on Psychedelic Salon and Women in the Wild[02:30] Introducing Week 2 and the HRT cognition question[03:45] Menopausal symptoms and cognitive risk[05:00] What hormone therapy research actually shows[06:30] Estrogen as a neuroprotectant[08:30] Brain changes during midlife[10:00] Psychedelics and neuroplasticity[11:30] Personal reflections on anxiety and action[13:30] Reflection questions for listeners[15:00] Micro-Psyched program overview and what’s next🔵 Additional ResourcesOriginal Week 2 post on SubstackEpisode 55: Ketamine-Assisted Therapy: Brain Effects ExplainedWomen in the Wild - Reserve your spot! Learn more about this episode: https://aprilpride.substack.com/p/microdosing-for-midlife-estrogen-cognitionHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

118. Microdosing for Midlife: Intention Setting, Integration, and Finding Your Dose (Week 1)Week 1 of Microdosing for Midlife explores intention setting, finding the right microdose, and integrating psilocybin gently during midlife transitions.Episode SummaryThis episode marks Week 1 of Microdosing for Midlife, a 12-week audio series exploring how psilocybin microdosing for women can support emotional awareness, intention, and integration during midlife transitions.In this opening installment, April Pride reads and expands on the first essay in the series, focused on intention setting and finding the right dose, while grounding the conversation in lived experience. Drawing from her own midlife hormonal transition, grief, and identity shifts, April frames microdosing as an integration practice that unfolds during daily life, rather than something that happens after a peak experience.The episode introduces why midlife—particularly during perimenopause and emotional regulation shifts—can be a uniquely potent time for this work. Listeners are invited to consider intention not as an outcome-driven goal, but as a present-moment orientation that supports nervous system regulation in midlife and long-term change.This episode serves as an audio companion to a Substack essay, offering context, reflection, and integration insights that stand on their own without replacing the original written post.🔵 Key Takeaways• Why midlife is a neurological, hormonal, and emotional transition• How microdosing supports integration during daily life• Intention setting in microdosing versus goal-setting• Nervous system regulation in midlife• Hormones, neurotransmitters, and emotional resilience• Microdosing protocol safety considerations• Why community-based psychedelic education supports accountability🔵 Timestamps[00:00] Series introduction and safety framing[02:00] Why this series is being shared as audio[03:00] Midlife as a period of sovereignty and transformation[04:30] Psychedelic integration practice in real time[05:30] Intention versus goals in microdosing[06:45] Hormones, neurotransmitters, and the midlife brain[07:45] Finding the right microdose and cadence[09:00] Safety considerations before beginning[09:45] Why microdosing should not be done in isolation[11:00] Listener questions and common concerns[12:30] What’s next in the 12-week microdosing series🔵 Additional ResourcesOriginal Week 1 post on SubstackEpisode 72: Preparing for a Psychedelic Journey SafelyWomen in the Wild applicationLearn more about this episode: https://aprilpride.substack.com/p/microdosing-for-midlife-intention-integration-week-1Hosted by April Pride Subscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

117. Ibogaine Therapy Safety & Ethics: What Responsible Care Really Looks LikeA grounded conversation on ibogaine therapy safety and ethics—covering medical oversight, risks, integration, and responsible psychedelic care.Episode SummaryIbogaine is often described as a breakthrough for addiction, trauma, and PTSD—but it’s also one of the most medically complex psychedelic therapies in use today. In this episode, April Pride sits down with Tom Feegel and Talia Eisenberg, co-founders of Beond Ibogaine, to explore what ethical, medically supported ibogaine care actually requires.Together, they unpack the difference between iboga and ibogaine, why cardiac screening and clinical monitoring are non-negotiable, and how integration—not intensity—is where real change happens. Talia shares her personal recovery story, Tom explains Beond’s safety-first model, and April grounds the conversation in harm reduction, nervous system care, and responsibility. This episode will help you understand the real risks, the emerging science, and the ethical questions shaping ibogaine’s future—without hype or shortcuts.🔵 Key TakeawaysIboga and ibogaine are not the same—and that distinction matters for safety, dosing, and ethics.Ibogaine carries real cardiac risk and should never be used without medical screening and monitoring.Post-acute withdrawal can last weeks or months and is a major relapse risk without support.Whole-plant medicines vary in potency; predictability is a safety issue, not a comfort preference.Integration starts before the medicine and continues long after—it’s a way of living, not a checklist.🔵 Timestamps[00:00] Safety disclaimer, why harm reduction matters, and setting the context[01:00] Iboga vs. ibogaine: what’s the difference and why it matters[03:00] Tom’s story: trauma, recovery, and building the place that didn’t exist[07:30] Talia’s first ibogaine experience and the risks of unregulated care[09:00] What post-acute withdrawal really looks like[12:00] Spiritual seeking, Osho, and early inner guidance[14:00] “Root medicine” and why support after the experience is critical[17:00] Potency variability: mushrooms, cannabis, and iboga compared[18:00] Cardiac risk, medical screening, and ethical boundaries[23:00] PTSD, TBI, and what the emerging research suggests[27:00] Cannabis use disorder, ketamine, kratom, and modern dependency patterns[31:00] What a medically supported ibogaine program actually includes[34:00] Integration vs. activation: turning insight into lived change[38:00] How to evaluate whether ibogaine care is right for you🔵 GuestsFollow Tom Feegel & Talia Eisenberg: Beond Ibogaine | https://beondibogaine.com | https://www.instagram.com/beondibogaine🔵 Additional ResourcesSetSet Psychedelic CardsWomen in the Wild applicationLearn more about this episode: https://aprilpride.substack.com/p/ibogaine-therapy-safety-and-ethicsHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

116. Psychedelics and Aging: Meaning in Later LifeAn educational conversation on psychedelics and aging, exploring meaning-making, grief, safety, and integration through lived experience and research.Episode SummaryWhat happens when psychedelic experiences arrive later in life—after careers, caregiving, grief, and loss have already shaped the nervous system? In this episode, April Pride sits down with journalist and author Abbie Rosner to explore psychedelics and aging through the lens of elderhood, meaning-making, and maturity. Rather than framing psychedelics as a return to youth, this conversation looks at how these experiences can land differently for older adults—bringing reflection, perspective, and emotional capacity rather than novelty or intensity. Together, April and Abbie discuss research on end-of-life anxiety, lived experiences of grief and joy, and why preparation, support, and integration matter more than peak experiences. This episode offers a grounded, harm-reduction–oriented exploration of what psychedelics may offer later in life—without hype, pressure, or promises.🔵 Key TakeawaysPsychedelics often land differently later in life because the nervous system carries decades of lived experience.Elderhood is not decline—it’s integration of youth, age, wisdom, and impermanence.Research on psychedelics and end-of-life anxiety points to increased emotional capacity, not the elimination of grief or fear.Challenging experiences are not uncommon, but preparation and support can reduce long-term difficulty.Community becomes increasingly important for integration, care, and meaning as we age.🔵 Timestamps[00:00] Why psychedelics and aging require a different conversation[02:30] Abbie Rosner’s journey into psychedelics later in life[05:30] Seniors vs. elders and why language matters[07:15] Elderhood as integration, not decline[11:25] Meaning making, mortality, and end-of-life research[14:20] What older adults seek from psychedelic experiences[21:00] Harm reduction, challenging experiences, and safety[26:00] Preparation pathways: legal, underground, and supported options[29:00] Psychedelics, grief, and emotional release[33:00] Community, mutual care, and aging with intention[36:50] Integration over intensity: closing reflections🔵 GuestsAbbie Rosner is a journalist and author focused on psychedelics and aging, and elderhood. Her forthcoming book explores how psychedelic experiences intersect with meaning making, grief, and community later in life.Follow Abbie Rosner: Elderevolution on Substack | Instagram — @elderevolution🔵 Additional ResourcesSetSet Psychedelic CardsWomen in the Wild applicationLearn more about this episode: https://aprilpride.substack.com/p/psychedelics-and-agingHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

115. 5-MeO-DMT Experience ExplainedA grounded conversation on the 5-MeO-DMT experience—how it affects the nervous system, how it differs from DMT, and why safety and integration matter.Episode SummaryWhat is 5-MeO-DMT, and why do people describe it so differently from other psychedelics?In this episode, April Pride sits down with licensed clinicians and facilitators Roger and Dustin to explore the 5-MeO-DMT experience through both lived experience and emerging neuroscience. Often referred to as the God molecule psychedelic, 5-MeO-DMT is widely described as a non-visual psychedelic experience—one that quiets the nervous system rather than amplifying imagery, stories, or symbols.Together, they break down 5-MeO-DMT vs DMT, explain how this compound interacts with serotonin receptors in the brain, and discuss why many people report profound ego dissolution, nervous system regulation, and long-term shifts in how they experience safety and connection.This episode also centers women and psychedelics, examining why women—particularly those who have spent years in control, caretaking, or emotional labor—may feel especially drawn to this form of surrender-based medicine.If you’re seeking grounded insight into psychedelic harm reduction, integration after 5-MeO-DMT, and what makes this medicine fundamentally different from other psychedelic experiences, this conversation is an essential listen.🔵 Key TakeawaysThe 5-MeO-DMT experience is often felt rather than seen, with little to no visuals or narrative contentUnlike classic psychedelics, 5-MeO-DMT is widely described as a non-visual psychedelic experienceUnderstanding 5-MeO-DMT vs DMT is critical—many vape pens labeled “DMT” contain N-N-DMT, not 5-MeO-DMT5-MeO-DMT strongly activates both 5-HT2A and 5-HT1A serotonin receptors, impacting cognition and nervous system regulationThe medicine often quiets the nervous system rather than stimulating imagery or meaning-makingSynthetic 5-MeO-DMT allows for more precise dosing and supports harm reduction by protecting the Sonoran Desert toadWomen may experience particular resonance due to lifelong patterns of regulation, control, and emotional laborPsychedelic integration after 5-MeO-DMT is essential; the effects unfold over time, not just during the sessionScreening, contraindications, and aftercare are non-negotiable components of responsible psychedelic use🔵 Timestamps[00:00] What people mean when they describe the God molecule psychedelic[02:10] How Roger and Dustin came to work with 5-MeO-DMT[03:36] Why this is a non-visual psychedelic experience[04:22] Synthetic vs toad-derived 5-MeO-DMT and harm reduction[06:57] Why some therapeutic “stuckness” responds differently to 5-MeO-DMT[08:28] Serotonin receptors and psychedelics: the double-door explanation[10:00] Nervous system regulation and surrender, especially for women[11:14] Gamma brainwaves, endogenous release, and embodied remembering[13:41] April’s experience with DMT vapes and common confusion[16:19] Clear distinctions between 5-MeO-DMT vs DMT[18:30] Health risks, medications, and serotonin syndrome[20:30] Ketamine, DMT, and the limits of comparison[22:53] Why women and psychedelics intersect uniquely here[23:21] Integration, meaning-making, and what comes after the experience🔵 GuestsRoger & DustinLicensed clinicians and facilitators at Sky Mountain Retreats, specializing in carefully screened, harm-reduction-focused 5-MeO-DMT experiences with an emphasis on preparation, precision dosing, and long-term integration.🔵 Additional ResourcesSetSet Psychedelic CardsWomen in the Wild applicationLearn more about this episode: https://aprilpride.substack.com/p/5-meo-dmt-experience-nervous-system-safetyHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

114. How to Start Microdosing with PsilocybinA science-backed guide to microdosing psychedelics with SetSet’s 12-week protocol, featuring expert insight and lived experience.Episode SummaryIf you’ve been microdose-curious — or maybe you’re already experimenting and want a little more structure — this episode is your map. Host April Pride pulls together insights from SetSet collaborators including author Amy Wong, integrative therapist Kendra Bloom, and medicine woman Sand Symes.You’ll learn exactly what microdosing is, why it works, and how SetSet’s 12-week Micro-Psyched protocol guides real, sustainable shifts—especially for women navigating overwhelm, transitions, or burnout.Whether you’re a total beginner or an experienced journeyer seeking structure, this episode will help you align mindset, medicine, and method.🔵 Key TakeawaysMicrodosing is a sub-perceptual, regular-dose protocol designed to shift your mental patterns gently over time.There are three main microdosing personas: psychedelic curious, psychedelic conscious, and providers supporting others.Microdosing supports subtle but profound behavior changes—like reducing compulsions or regaining clarity.SetSet’s 12-week structure mirrors the natural cycle of change: preparation, resistance, and consolidation.Real change doesn’t require fireworks. Tiny, steady choices reshape your reality.🔵 Timestamps00:36 What microdosing really is and how it works (Amy Wong)02:10 Three types of people who join SetSet’s protocol08:45 Why structure matters: stories from women in Micro-Psyched13:20 Real-life benefits from microdosing: cravings, clarity, choice18:00 Why 12 weeks? The brain’s timeline for transformation21:40 Live workshops: coming to Seattle in 202524:00 What’s included in SetSet’s Annual Membership27:10 Final reflections: microdosing as a relationship, not a hack🔵 GuestsAmy Wong: Author of Living on Purpose | amywong.comKendra Bloom: Therapist, Integration Specialist | @kendrabloomSand Symes: Medicine woman and facilitator | @sandsymes🔵 Additional ResourcesQ: How Do Psychedelics Unlock Creativity?Micro-Psyched 12-Week Microdosing ProgramWomen in the Wild applicationLearn more about this episode: https://aprilpride.substack.com/p/how-to-start-microdosing-psilocybinHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

113. Psychedelic Law in Seattle: What’s Actually Legal in 2025?SetSet Salon breaks down psychedelic law in Seattle with attorneys Perry Salzhauer & Daniel Shortt—what the entheogen resolution covers, what it doesn’t, and the risks it creates.Episode SummaryMost people think Seattle has legalized psychedelics. It hasn’t—at all. In this episode, recorded live at SetSet’s Psychedelic Salon at Town Hall Seattle, host April Pride sits down with attorneys Perry Salzhauer and Daniel Shortt—two of the most respected legal voices shaping psychedelic and cannabis policy in the U.S.Together, they break down psychedelic law in Seattle, clarify what the city’s 2021 Entheogen Resolution really allows (and what it absolutely does not), and explain the risks around gifting, cultivating, and even discussing psychedelics in a professional setting.If you’re microdosing quietly, contemplating a community container, or considering any psychedelic-related offering, this episode is your essential legal literacy guide.Frequently Asked Questions About Psychedelic Law in Seattle1. Is psilocybin legal in Seattle?No. Psilocybin is still illegal under Washington state and federal law. Seattle’s 2021 resolution merely deprioritizes enforcement for certain activities such as possession, gifting, and small-scale cultivation.2. What does “decriminalized” actually mean in Seattle?Seattle has not decriminalized psychedelics. Instead, the City Council instructed law enforcement to place the lowest priority on pursuing cases involving noncommercial entheogen possession, gifting, and cultivation.3. Can I legally buy mushrooms in Seattle?No. Any form of purchasing—even disguised transactions like “stickers,” “sandwiches,” or “cover charges that include mushrooms”—falls outside the resolution and can still lead to prosecution.4. Is gifting psychedelics allowed?Gifting without any compensation—money, labor, products, services, or “value”—is deprioritized for enforcement.However, anything that resembles a commercial transaction can increase legal risk.5. Can I grow mushrooms at home in Seattle?Cultivation is formally deprioritized under the city resolution, but still illegal under state and federal law. There is no legal safe harbor for personal cultivation.6. Are psychedelic therapy sessions legal in Washington?No. Washington has no legal pathway for psychedelic-assisted therapy. Colorado currently offers the safest regulated route for professionals seeking to integrate entheogens into clinical practice.🔵 Resources- Upcoming Psychedelic Salon at Town Hall Seattle- SetSet’s Psychedelic Toolkit - Micro-Psyched 12-Week Microdosing Program- Perry Salzhauer & Daniel Shortt: Attorneys at Salzhauer & Shortt | salzhauershortt.comLearn more about this episode: https://aprilpride.substack.com/p/psychedelic-law-seattle-entheogen-decriminalizationHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

112. Epidemic of Fear: How Psychedelics Help Us Transcend StucknessDiscover how psychedelics help retrain the nervous system to move from fear to flow. April Pride explores the roots of stuckness, the Hero’s Journey, and how microdosing and macrodosing support nervous system healing.🔵 What You’ll Learn- Why fear is the defining epidemic of our time—and how it paralyzes potential.- How Traditional Chinese Medicine, neuroscience, and psychedelics all point to fear as stuck energy—and what to do about it.- The biological mechanisms behind psychedelics’ ability to downregulate fear-based responses and support nervous system healing.- Why flow, faith, and nervous system regulation are the antidotes to fear—and how SetSet’s integration-first approach mirrors the Hero’s Journey.🔵 Key Takeaways- Fear isn't the enemy—it's a threshold guardian. It signals that you’re close to a transformation.- Psychedelics like psilocybin, MDMA, ketamine, and LSD help retrain the nervous system, soften the amygdala, and create new associations.- Microdosing is a nervous system rehearsal, teaching the body that “this cue is safe.” Over time, safety becomes a state, not a goal.- Flow = faith in motion. It’s not about erasing fear—it’s about metabolizing it into freedom.🔵 Resources - April’s Substack series: Microdosing for Midlife- SetSet Psychedelic Card Deck- Town Hall Seattle SalonsLearn more about this episode: https://aprilpride.substack.com/p/epidemic-of-fear-psychedelics-stucknessHosted by April PrideSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

111. Trip Report: Kanna vs. MDMA Plus How Molly Effs With Your Sleep For WeeksWhat if you could feel more connected, relaxed, and joyful—without alcohol or MDMA? In this episode, I talk to Andrew Weisse, founder of getKanna and writer of Substack's The Psychedelic Blog, about the mood-enhancing, heart-opening power of Kanna, a South African plant that’s gaining popularity as a functional empathogen. We discuss its chemical makeup, traditional use, and modern applications for social connection, romantic intimacy, and MDMA replacement. This is a big one for anyone exploring a sustainable way to engage with psychedelics.🔵 Key Takeaways- Kanna enhances emotional openness, connection, and calm without a crash or sleep disruption- It’s a serotonin reuptake inhibitor, not a psychedelic—legal and gentle- Unlike MDMA, Kanna is non-depleting and can be taken more regularly- April shares her sober-in-Seattle story with Kanna as her “plus one”- Andrew offers insights on sourcing, dosing, and why alcohol-free connection is the futureLearn more about this episode, including guests and resources on Substack: https://aprilpride.substack.com/p/mdma-vs-kanna-trip-report-with-andrew-weisse-the-psychedelic-blogHosted by April PrideFeaturing Andrew Weisse, getKanna and The Psychedelic BlogSubscribe for April’s newsletter on Substack at https://aprilpride.substack.com/subscribe or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

110. How to Rethink Drinking Without "Hitting Rock Bottom"What if your relationship with alcohol doesn’t require a dramatic rock-bottom moment to change? In this episode of SetSet, I sit down with sobriety coach Martha Wright, who went from building a life around wine—professionally and personally—to questioning its role in her daily rituals. Just as I did with cannabis. Together, Martha and I explore what it means to be a “gray area drinker,” how midlife hormonal shifts impact our cravings and consumption, and how reframing our beliefs about alcohol can free us from it—without shame or labels. This conversation is rich in neuroscience, compassion, and personal insight, offering a fresh and empowering approach to alcohol use.🔵 Key Takeaways- Gray area drinking impacts 80% of alcohol consumers—many of whom don’t identify as addicts but still want change.- Willpower isn’t enough—rewiring the brain’s dopamine reward system is key to sustainable change.- Cultural myths about “normal drinking” prevent many women from questioning their habits.- Midlife hormonal shifts (like menopause) significantly impact alcohol tolerance and desire.- A “luscious sabbatical” from alcohol can reawaken sensory pleasure, curiosity, and joy.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/rethinking-alcohol-martha-wrightHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

How MDMA Is Transforming Love, Aging & GriefMany people think MDMA is a party drug. What if it’s actually a medicine for seniors?Episode 111 of the SetSet Podcast. Join us for this deeply personal, science-backed live recording of our August virtual Psychedelic Salon. I was joined by Charley Wininger, licensed therapist and author of Listening to Ecstasy, and his wife Shelly, who introduced Charley to MDMA and inadvertently changed both their lives.This episode unpacks how MDMA has enhanced their relationship, deepened their intimacy, helped process grief, and brought unexpected youthful vitality back into their lives. We touch on everything from safe use protocols to sex, aging, grief, and even using MDMA to support decision-making during divorce.It’s a joyful, intimate conversation rooted in love, community, and years of experience. A must-listen for anyone curious about the intersection of psychedelics, aging, and emotional healing.🔵 Key Takeaways- MDMA can bring back vitality, joy, and intimacy in aging couples.- Grief and trauma are central to many people’s suffering—and MDMA can offer a path to healing.- Proper protocols and post-use care make a huge difference in experience and recovery.- Seniors face unique considerations around prescription meds and safety—but age isn’t a disqualifier.- Community, connection, and shared experiences amplify MDMA’s therapeutic effects.🔵 Timestamps[00:00] Introduction by April Pride[01:00] Charley and Shelly’s love story and MDMA origin[04:00] MDMA for connection, not just therapy[07:00] Microdosing vs. full doses for aging bodies[10:00] Reclaiming joy and youth in your 60s and 70s[13:00] Protocols, safety, and navigating medications[17:00] Using MDMA to address grief after major loss[22:00] Intimacy, sex, and MDMA in long-term relationships[27:00] Can MDMA help save or end a marriage?[31:00] FDA, safety concerns, and overlooked age groups[37:00] Community healing: Potlucks, shared rolls, and one pulse[41:00] Advice for couples using MDMA without a guide[49:00] Final reflections and upcoming events🔵 Featured GuestsCharley Wininger – Licensed therapist, author of Listening to Ecstasy📘 charleywininger.comShelly Wininger – Former critical care nurse, cannabis advocate, and spiritual explorerSubscribe to get SetSet with psychedelics!Learn more about this episode, including guests and resources on https://aprilpride.substack.com/p/psilocybin-mushrooms-beyond-the-tripHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

109. How Psilocybin Microdosing Supports Menopause: A Brain-Based GuideHow can women navigate the emotional, cognitive, and hormonal rollercoaster of perimenopause and menopause? In this episode, April Pride explores how psilocybin microdosing may offer real support for women in midlife. From balancing neuroplasticity and mood to improving sexual function and breaking addictive patterns, this conversation highlights the science, lived experience, and emerging protocols behind psilocybin’s potential to ease this complex life stage. If you're wondering how to recalibrate your brain (not just your hormones), this episode offers data-backed, compassionate insights into how psychedelics fit into midlife care.🔵 Key Takeaways-Hormonal shifts in perimenopause and menopause deeply impact brain function, mood, and resilience.-Psilocybin may support neuroplasticity, emotional regulation, and cognitive clarity during these transitions.-Microdosing could help improve libido, body image, and intimacy—areas often impacted by hormonal decline.-Midlife women are increasingly self-medicating with psychedelics to manage menopause-related symptoms.-Community support and intentional protocols are critical for safe, effective microdosing.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/how-psilocybin-microdosing-supports-menopauseHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

108. Why Bong Design Matters for Modern Women: Esther Ramirez from Session GoodsWhat if your bong could live on your coffee table—without shame or splashback? In this 4/20 Easter special, April Pride sits down with Esther Lenore Ramirez, co-founder and CEO of Session Goods, to explore how minimalist bong design supports women who want elegant, intentional tools for cannabis. From design trade-offs (no percs, no ice pinches) to the bong’s global history, this episode reclaims what it means to be a woman who smokes. Esther shares how clean glassware, thoughtful accessories, and user-friendly dimensions offer a new kind of cannabis ritual—especially for women coming back to the plant after a long hiatus.🔵 Key Takeaways-Designing a bong for your lifestyle means no splash guards, no logos—just clean lines and easy cleanup.-Session Goods took cues from wine decanters and candle bases to create pieces that blend in beautifully.-Glass fuming, color limitations, and mouthpiece angles all matter—especially when lipstick and group sharing are in play.-The word “bong” likely comes from Thai, but the evolution of glassblowing gave us the modern version we know today.-Homegrown cannabis or mushroom gifts add emotional connection and storytelling to the ritual of use.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/modern-bong-design-for-women-who-smokeHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

107. Psilocybin for Menstrual Cycles and Menopause: A Women’s Wellness ProtocolHow can mushrooms sync with your cycle—or shift your experience of menopause? In this episode, April Pride is joined by Jennifer Chesak, author of The Psilocybin Handbook for Women, to decode the powerful relationship between psilocybin and women’s hormones. Together, they explore the latest research, ancestral wisdom, and practical strategies for using psychedelics across different phases of a woman’s life. From syncing mushroom journeys with ovulation to microdosing through perimenopause, this conversation empowers women to tailor their approach to their unique physiology. Expect science, storytelling, and no-BS protocol advice grounded in lived experience.🔵 Key Takeaways-Psilocybin affects the menstrual cycle via the stress-regulating HPA axis, with possible benefits like cycle regulation or early onset.-Optimal time to journey is near ovulation, when energy and estrogen levels support a deeper experience.-Indigenous wisdom aligns with new science, reinforcing cycle-aware practices for safe, intentional use.-Psilocybin can support perimenopause by easing depression, improving libido, and helping resolve trauma.-A microdosing protocol should be personal—guided by intuition, not rules made by men.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psilocybin-menstrual-cycles-menopauseHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

106. Natural Psychedelics and the Healing Power of CommunityWhat if the most potent medicine isn’t just the mushroom or the ceremony—but the community that holds you through it? In this soul-stirring conversation, host April Pride continues her dialogue with healer and teacher Satya on the role of natural psychedelics in helping women heal trauma and reconnect with their core selves. From the roots of survival instinct to the chemistry of trust, they explore why healing doesn't happen in isolation—and how community care, spiritual insight, and ethical facilitation are essential to any psychedelic journey. Whether you're new to plant medicine or rethinking your own integration path, this episode grounds the mystical in the everyday and reminds us: the real work happens after the trip.🔵 Key Takeaways-Natural psychedelics help dissolve survival-based trauma that keeps women disconnected from themselves and others.-True healing starts after the retreat. Integration, accountability, and sustained connection are what turn insights into change.-Community support is non-negotiable. Healing happens in safe, nonjudgmental spaces—not in isolation.-Facilitator integrity is critical. Training, experience, and humility must precede serving psychedelic medicine.-We must reframe our cultural obsession with more. Sometimes awe, not intensity, is the deepest form of medicine.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/natural-psychedelics-for-trauma-healingHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

105. Integrating Science and Spirituality: A New Framework for Psychedelic HealingWhat does it mean to truly heal in a psychedelic space? In this episode, host April Pride is joined by Satya—a seasoned facilitator whose work bridges psychotherapy, meditation, and natural psychedelic therapy. Together, they unpack how conscious language, sacred space, and personalized protocols shape transformative outcomes. From working with trauma survivors and cancer patients to designing women-only retreats for deep healing, Satya reveals how integrating science and spirituality can unlock layers of self that pharmaceuticals and talk therapy alone cannot reach. If you’re questioning whether psychedelics are for you—or how to choose between a retreat with or without medicine—this episode helps you explore those decisions through the lens of compassion, integrity, and feminine wisdom.🔵 Key Takeaways-Psychedelic healing is not one-size-fits-all—the path begins with your needs, history, and readiness.-Language shapes experience. Conscious facilitation means guiding, not imposing, especially during altered states.-Cancer patients, trauma survivors, and military veterans have unique responses and needs in integration work.-Women’s-only spaces allow for safer, deeper healing, especially for survivors of sexual trauma or body image issues.-Science and spirituality aren’t opposites—they’re complementary tools for individual and collective healing.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/science-meets-spirit-psychedelic-healingHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

104. How Microdosing for Women Rewires Habit, Hormone, and Healing CyclesHow does a microdose change a life? In this powerful conversation, April Pride returns with part two of her interview with guide Sand Symes to unpack what really happens when women begin a psychedelic microdosing protocol. From rewiring somatic patterns to clearing menopausal brain fog, this episode explores how subtle shifts lead to seismic inner changes. Sand shares her personal experience as well as insights from guiding others through emotional healing with psychedelics. Expect science-backed nuance, spiritual depth, and hard-won clarity on how to start integrating psychedelics into a sustainable practice—especially for women navigating midlife. Whether you're microdosing out of curiosity or crisis, this episode offers community and guidance on your path forward.🔵 Key Takeaways-Microdosing can quietly interrupt deeply held somatic habits, from sugar cravings to codependent relationships.-Hormonal shifts like menopause can be softened by psychedelics—Sand describes brain fog lifting mid-protocol.-Integration isn’t optional. It's how the medicine keeps working long after the last dose.-Doing it alone? Not ideal. Community is key to meaningful psychedelic integration, especially for women.-Microdosing supports spiritual clarity, emotional regulation, and better decisions—one subtle shift at a time.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/microdosing-for-womenHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

103. Feminine Psychedelic Power: Healing Stories from the Inside OutIn this soulful and story-rich episode, April Pride welcomes Sand Symes, a guide with decades of experience guiding women through psychedelic journeys. Together, they explore how feminine energy—when supported by plant medicine like psilocybin, cannabis, and MDMA—can become a powerful portal to emotional liberation and embodied truth. Through lived experience and clinical wisdom, Sand unpacks why traditional therapy often falls short for women and how sacred psychedelics offer a different kind of transformation—rooted in intuition, ancestry, and nervous system recalibration. If you’ve ever wondered what it looks like to prepare for a journey as a woman, or why psilocybin healing feels so personal, this conversation will meet you where you are.🔵 Key Takeaways-Feminine energy healing with psychedelics helps women release outdated stories embedded in their nervous systems.-Sand Symes shares her journey from social work to sacred medicine, working with psilocybin, cannabis, and MDMA.-Psychedelics help rewire trauma responses and open a deeper connection to ancestral and intuitive wisdom.-The power of preparation and integration: true healing begins before and continues long after the journey.-These medicines invite sovereignty, not escapism—women reclaim their truth through presence and self-compassion.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/feminine-energy-healing-with-psychedelicsHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

102. Is At-Home Ketamine Treatment Safe for Women with Trauma?In this powerful second conversation with author and mental health advocate Kaia Roman, host April Pride explores the clinical, emotional, and cultural dimensions of at-home ketamine treatment—particularly for women navigating trauma, depression, and midlife transitions. With brutal honesty and personal insight, the two discuss dissociation, PTSD, accessibility, and whether at-home ketamine is a fit for women with a history of sexual trauma. This episode doesn’t shy away from the hard questions: Can ketamine help with suicidal ideation? What’s the difference between medical and spiritual dissociation? How do we keep these treatments safe, affordable, and trauma-informed? Whether you're ketamine-curious or rethinking your mental health toolkit, this episode delivers the science, story, and support you need.🔵 Key Takeaways-Ketamine therapy offers rapid relief for depression, PTSD, and even suicidal ideation—especially when traditional meds fail.-At-home ketamine treatment must be guided and never done alone, especially for trauma survivors.-Dissociation in ketamine can be healing—not retraumatizing—when properly supported.-Initial protocols often require 4–6 sessions in 2–3 weeks, with boosters tailored to the individual.-Ketamine is a safe, flexible tool with almost no side effects—but it's not a one-and-done solution.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/at-home-ketamine-for-womenHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

101. Ketamine for Emotional Healing: Divorce, Depression, and Dosing with Kaia RomanWhat happens when your life falls apart—and a new path reveals itself through ketamine-assisted therapy? In this vulnerable and science-savvy episode, April Pride talks with Kaia Roman, author of The Joy Plan, about using ketamine for emotional healing during divorce and lockdown. Kaia breaks down how different types of ketamine administration affect your brain, what it actually feels like to dissociate, and why set and setting are non-negotiables. Whether you’re skeptical of psychedelics or searching for a safe reset, this conversation blends research, real talk, and deeply personal insights on what it means to grow through rupture.🔵 Key Takeaways-Ketamine can help interrupt depressive loops and open windows for rewiring the brain—especially during high-stress events like divorce.-Intramuscular injections may offer a deeper experience than IV or lozenges, though dosage control is trickier.-At-home ketamine lozenges offer accessibility and affordability—but sublingual absorption is only ~25% compared to other methods.-Spravato, the nasal S-ketamine, is FDA-approved but may activate opioid receptors, making it less ideal than clinical or at-home lozenge treatments.-Integration support is crucial. Post-session neuroplasticity offers a rare chance to rewire thought patterns and behaviors.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/ketamine-for-emotional-healing-divorceHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

100. 100 Episodes In: What We’ve Learned About Psychedelic Therapy for WomenThis milestone episode is a love letter to our listeners. April Pride marks 100 episodes of SetSet by reflecting on what’s changed—and what still needs changing—in the conversation around psychedelic therapy for women. From the rise of ketamine clinics to our monthly psychedelic integration Salons, SetSet continues to fill the critical gaps in education, safety, and community. In this episode, April reads listener reviews, previews our latest Salon on psychedelics and depression, and shares why science alone isn't enough without lived experience and practical tools for transformation.🔵 Key Takeaways-100 episodes in, the need for clear, science-backed education around psychedelics is more urgent than ever.-Listener feedback highlights SetSet as a top resource on ketamine for depression—more helpful than many providers.-Integration is essential: taking the medicine is only the beginning of the transformation process.-SetSet’s monthly Salon series and downloadable guides bridge the gap between clinical knowledge and real life.-Community reviews show that honest, digestible education helps listeners feel less alone and more empowered.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psychedelic-therapy-for-womenHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

99. Ketamine Therapy for Women: Healing Trauma and Depression at HomeHow does healing begin when traditional mental health tools fall short? In this episode, April Pride continues her conversation with Jennifer Whetzel—branding expert, researcher, and founder of the Women in Cannabis Study. Together, they unpack the role of at-home ketamine therapy in treating major depression and PTSD. Jennifer shares the rituals, risks, and realities of being a woman navigating both the cannabis and psychedelic space—and how creative integration practices like selfies, sparkle gardens, and AI storytelling transformed her healing. If you’re curious about how ketamine can help resolve trauma, or wondering whether microdosing is enough, this episode invites you into the lived experience of someone who’s done the work—twice a week, for years.🔵 Key Takeaways-Ketamine therapy for women can offer immediate relief from depressive episodes and PTSD—especially when combined with integration.-Women in cannabis often enter the industry for healing, but face burnout, sexism, and untreated mental health challenges.-Jennifer’s DIY integration rituals—like selfies and sparkle gardens—help prolong ketamine’s effects and create joy in daily life.-Misconceptions around long-term ketamine use can create shame, but some women need ongoing protocols to maintain stability.-New research and community stories are crucial to overcoming stigma and helping more women access safe, science-backed psychedelic care.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/ketamine-therapy-for-womens-mental-healthHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

98. At-Home Ketamine Therapy for Trauma: Jennifer Whetzel on Healing from the Inside OutWhat happens when traditional therapies stop working, but the healing isn’t done yet? In this episode, April Pride talks with Jennifer Whetzel—cannabis branding expert and creator of the Women in Cannabis Study—about how at-home ketamine therapy became a powerful tool for processing trauma, managing chronic pain, and rewiring lifelong emotional patterns. Jennifer gets personal about her years of pill dependence, alcohol use, and disordered eating—and how plant and psychedelic medicines helped her reclaim her agency, her creativity, and her calm. If you’ve been curious about trying ketamine but unsure where to start, this honest conversation offers insight, real-world protocols, and inspiration for your own healing journey.🔵 Key Takeaways-Ketamine therapy helps break trauma loops by offering access to self-compassion and clarity—especially when paired with meditation and integration.-Dissociation is therapeutic, not escapist. Jennifer explains how ketamine-induced disconnection from the body allowed her to access and reprogram her mind.-Cannabis and ketamine are not a cure-all. But together, they helped Jennifer taper off opioids and stabilize mental health without pharmaceuticals.-Guided meditation enhances ketamine’s benefits. ADHD made traditional meditation difficult—until she found tools that made inner stillness accessible.-Healing is not linear. From childhood trauma to adult surgery recovery, Jennifer’s story is a reminder that harm reduction is a valid and powerful strategy.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/at-home-ketamine-therapy-for-traumaHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

97. From Tour Buses to Trauma Work: Rachel Demy on Psychedelic Healing PhotographyWhat happens when a touring photographer turns the camera inward? In this episode, April Pride sits down with Rachel Demy—longtime Death Cab for Cutie crew member turned fine art photographer—to explore how addiction, trauma, and psychedelics shaped her latest solo exhibition. Demy shares how a prescribed medication led to addiction and ultimately sparked a profound creative reckoning. From managing bands to managing her shadow, Rachel’s story invites us to rethink what recovery and self-expression can look like. You’ll also hear about the upcoming Psychedelic Salon at Town Hall Seattle, where Rachel will appear alongside Tim Keck (The Stranger, Mush Love Podcast) to explore psychedelic healing photography and the art of seeing through new eyes.🔵 Key Takeaways-Rachel’s path to photography started with band management and evolved into documenting emotional landscapes.-Prescribed Vyvanse led to an unexpected addiction that reshaped her creative process.-Her photo series explores four stages of personal collapse: high, disintegration, dissolution, and healing.-Shadow work—common in psychedelic therapy—is reflected in her night photography and themes of home, loss, and self.-Rachel's upcoming show invites others into the conversation around addiction, recovery, and visual storytelling.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psychedelic-healing-through-photographyHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

96. Why Functional Mushroom Coffee Might Be the Future of WellnessCurious about the magic behind mushroom coffee? In this episode, we’re sharing a feed drop from the Mush Love Podcast hosted by Tim Keck, featuring Wonderground founder Jody Hall. From Cupcake Royale to cannabis edibles to mushroom adaptogens, Jody's journey is one of bold pivots and deep purpose. Tune in as she unpacks the science and story behind functional mushroom coffee, why she believes fungi are the future, and how her brand Wonderground is making this wellness ritual as joyful and powerful as your favorite cup of joe. Whether you're mushroom-curious or already sipping adaptogens daily, this episode offers a fresh, grounded perspective on stress, connection, and what makes a business truly healing.🔵 Key Takeaways-Functional mushroom coffee blends mood-boosting adaptogens with familiar rituals—without sacrificing taste.-Mushrooms like reishi, lion’s mane, cordyceps, and chaga offer brain, immune, and stress support.-Jody Hall's journey from cupcakes to cannabis to coffee shows how connection drives innovation.-Cupping and roasting techniques at Wonderground ensure both flavor and efficacy in each brew.-Mushroom wellness is growing fast—and it’s not just hype. It’s rooted in ancient medicine and modern science.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/functional-mushroom-coffee-for-mood-brain-healthHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

95. What’s Really in Your Mushroom Bar? The Truth About Psilocybin Product SafetyWhat if your “mushroom chocolate” has no mushrooms at all? In this eye-opening episode, April Pride continues her conversation with Joe Robinson, founder of PsiloSafe, to unpack the chaotic world of unregulated psychedelics. They dive deep into psilocybin product safety, how to find a trustworthy facilitator, and why synthetic alternatives like 4-ACO-DMT are complicating the therapeutic landscape. Whether you're sourcing for a therapeutic journey or just trying to avoid a gas station gummy trip gone wrong, this episode brings clear, grounded advice on navigating the modern mushroom marketplace.🔵 Key Takeaways-Not all mushroom products contain actual mushrooms—many include synthetic compounds like 4-ACO-DMT.-Ask for referrals and trust your gut when choosing a psychedelic facilitator.-PsiloSafe is working to standardize safety practices from “spore to cure.”-Unregulated products pose risks—from potency issues to contamination and false labeling.-Safe psychedelic use requires ethical sourcing, trusted guides, and informed communities.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psilocybin-product-safetyHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

94. Can We Trust Psychedelics? Inside PsiloSafe’s Mission to Keep You SafeHow do we reduce harm as psychedelics move from sacred circles to Shopify carts? In this eye-opening episode, April Pride is joined by Joe Robinson, founder of PsiloSafe—a self-regulating initiative working to bring transparency, education, and safety standards to unregulated psilocybin products. They discuss the rise in psilocybin contamination, synthetic analogs like 4-ACO-DMT, and the urgent need for safe sourcing and consumer screening tools. Joe draws from his two decades in the medical industry and current role in branding psychedelic products to explain how PsiloSafe is raising the bar for safety—without waiting on the FDA. If you’ve ever wondered whether your mushroom chocolate is actually psilocybin, or how to avoid risk as a consumer or practitioner, this one’s for you.🔵 Key Takeaways-Not all psychedelics are what they claim. Products labeled as “psilocybin” often contain synthetic alternatives like 4-ACO-DMT—which may pose more risk.-Testing matters. PsiloSafe is creating standards for clean psilocybin products, even in unregulated markets, to prevent contamination and overdose.-Joe’s medical background informs his mission. With 20+ years in healthcare and pharma, Joe applies clinical thinking to psychedelic product safety and education.-Consumer screening is a game-changer. PsiloSafe is piloting tools to help users self-assess whether psychedelics are safe for them—based on health history.-Long-term use isn’t risk-free. April flags emerging evidence of cardiovascular concerns from repeated psilocybin use, urging listeners to stay curious—and cautious.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psilocybin-harm-reduction-with-psilosafeHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

93. Life Clarity Practice and Microdosing: The Self-Inquiry Ritual You Didn’t Know You NeededHow do we actually begin again—when the road ahead feels foggy, when our energy’s off, or we just feel like we’ve lost ourselves in the grind? In this episode, April Pride welcomes creative strategist and author Bonnie Wan to guide us through the Life Clarity Practice: a deceptively simple journaling ritual that gets to the heart of what we want, what’s in our way, and how to move toward what matters. Originally born from a moment of marital crisis, Bonnie’s “life brief” evolved into a published book—and a radically honest framework for personal transformation. This conversation maps how combining the life clarity practice with microdosing psilocybin can unlock clarity, creativity, and courage. Whether you’re in a midlife transition, facing relationship questions, or just need a reset, this practice is your invitation to begin again—with intention.🔵 Key Takeaways-The Life Clarity Practice is a journaling method rooted in creative strategy—and designed to clarify what you truly want.-It starts with getting messy: stream-of-consciousness writing without judgment to surface what’s been buried.-Once you’re honest on the page, your five “life brief” declarations can emerge—and guide small, meaningful daily actions.-Pairing this practice with microdosing opens up emotional honesty and access to your own internal truth.-Tiny changes can create massive shifts when rooted in clarity.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/life-clarity-practice-microdosing-guideHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

92. Amanita Muscaria for Anxiety and Focus: Beyond the TripIn this second half of her conversation with Christian Rasmussen, host April Pride explores the broader applications of Amanita muscaria beyond addiction recovery. Christian shares real-world stories from his customers, tips for safe preparation, and how this often misunderstood mushroom is helping people ease anxiety, restore emotional balance, and even sharpen cognitive function. From microdosing protocols to dream-enhancing Blue Lotus, this episode offers insight into Amanita’s powerful but subtle role in modern mental wellness.🔵 Key Takeaways-Amanita’s unique action on the GABA and glutamate systems may reduce anxiety and improve focus.-Unlike psilocybin, Amanita can deliver unconscious emotional healing without intense visuals.-Microdosing 2–3x/day with 0.5–1g consistently supports clarity and emotional regulation.-Amanita tea must be prepared with heat and acid (lemon) to reduce nausea and activate compounds.-Other legal herbs like Blue Lotus and Kava complement Amanita’s heart-opening and calming effects.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/amanita-muscaria-for-anxiety-and-focusHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

91. Amanita Muscaria and Addiction Recovery: One Man’s Path Off BenzosIn this episode, host April Pride talks with Christian Rasmussen, founder of MN Nice Ethnobotanicals and the largest Amanita muscaria merchant in the U.S. Christian shares his powerful story of overcoming addiction to opiates and benzodiazepines—and how the red-capped mushroom often dismissed as toxic helped him reclaim his life. The conversation dives deep into Amanita’s therapeutic potential, how it differs from psilocybin, and why microdosing this ancient fungus may be one of the most overlooked tools in addiction recovery and mental wellness.🔵 Key Takeaways-Amanita muscaria affects the GABA system, making it useful for tapering off benzos and alcohol.-Unlike psilocybin, Amanita works subconsciously, with minimal visuals or emotional flooding.-Microdosing Amanita 2–3x daily may help reduce anxiety, insomnia, and even trauma responses.-Proper drying and tea preparation are critical for safe use and reduced nausea.-MN Nice Ethnobotanicals is pioneering access to responsibly sourced and prepared Amanita.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/amanita-muscaria-addiction-recoveryHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

90. Therapeutic Microdosing for Emotional Clarity and Identity HealingIn this conversation between April Pride and Amy Wong Hope, we dive into the therapeutic power of microdosing psilocybin—not as a productivity hack, but as a personal practice to gently unravel conditioned identities and foster emotional clarity. Amy, a licensed social worker and psychedelic facilitator, shares how “small doses” became a tool for healing shame, reclaiming her cultural identity, and supporting clients through transitions. The episode traces the evolution of her co-authored book, Small Doses of Awareness, and the nuanced interplay between science, somatics, and spirituality. Whether you're new to psychedelics or seeking a more integrative microdosing protocol, this episode offers real talk on DIY approaches, the risks and rewards of self-led healing, and how to honor ancestral practices in modern therapeutic use.🔵 Key Takeaways-Therapeutic microdosing isn't about numbing or optimizing—it's about fine-tuning awareness and reconnecting with your body and emotions.-Amy Wong Hope’s microdosing journey began as a response to fertility questions—and unfolded into a healing modality for intergenerational shame.-The book Small Doses of Awareness is both journal and gentle guide, with prompts and space to track your experience.-Not everyone should DIY microdose alone—seek community or trusted resources before starting.-Integration means slowing down, questioning habits, and choosing presence over productivity.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/therapeutic-microdosing-with-amy-wongHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

89. MDMA-Assisted Healing & the Psychedelic Shift: A Therapist’s TakeWhat happens when the FDA says no to MDMA therapy—but the healing continues anyway? In this two-part conversation, April Pride sits down with Amy Wong Hope, a licensed social worker and MAPS-trained MDMA-assisted therapy facilitator, to explore how clinicians are navigating the shifting legal landscape and how healing can happen with or without the medicine. From altered states in trauma work to why integration (not the trip) is where transformation lives, this episode offers both grounded clinical insight and spiritual resonance. Whether you’re a skeptic, seeker, or somewhere in between, Amy’s perspective on MDMA-assisted healing invites us to think differently about what therapy can be—and what it demands of us.🔵 Key Takeaways-MDMA-assisted therapy offers access to self-love, compassion, and trauma healing—especially where talk therapy alone falls short.-The FDA’s rejection of MAPS’ application reveals deeper misunderstandings about non-linear, integrative approaches to mental health.-Healing is a system-level intervention: changing your life, not just your brain chemistry, is what sustains breakthroughs.-“Altered states for healing” can happen without substances—via mindfulness, deep therapeutic connection, or embodied practice.-Integration is a daily act of self-love—chop wood, carry water, repeat.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/mdma-assisted-healing-psychedelic-therapyHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

88. Set and Setting in a Box: How Psilocybin Integration Cards Spark Real ConnectionIn this episode, April Pride invites listeners into her Seattle high-rise past for a raw, unscripted session with the psilocybin integration cards. You’ll meet Summer, a first-time participant, and Tilson, the voice guiding her through the experience. No scripts, no substances—just prompts that help surface real insight and emotional vulnerability. April breaks down the set and setting design of these cards and explains why most people prefer using them while microdosing (or not dosing at all). Whether you're prepping for your first group mushroom ceremony or simply looking to deepen your next dinner party, this episode helps you understand how psychedelics—and tools like these—can shift the way we relate.🔵 Key Takeaways-The psilocybin integration cards create structured connection and support microdose prep without needing to be high.-Set and setting in a box refers to the way these cards prep your mindset and environment for meaningful altered-state experiences.-People open up more when they’re relaxed, curious, and prompted in non-obvious ways.-Most participants found under 1 gram—or just a microdose—the ideal pairing with the cards.-Even without medicine, the cards prompt authentic, lasting connection—no trip required.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psilocybin-integration-cards-for-connectionHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

87. High Tech Weed & Design-Forward Devices: Reimagining the RitualWhat happens when cannabis goes digital—and women lead the conversation? In this design-forward episode, April Pride continues her conversation with writer Clare Sausen of High Design, diving into how tech meets tradition in today’s cannabis world. From elegant weed hookahs to concentrate vapes, the duo covers form, function, and how gendered design shifts what we smoke—and how we socialize around it. This episode explores the evolution of cannabis gadgets, the aesthetics of homegrown vs. high tech, and why accessibility, aging, and user experience matter more than ever.🔵 Key Takeaways-High tech weed devices like dry herb vapes and digital hookahs are elevating the smoking experience while softening the stigma.-Accessibility, aesthetics, and lung-friendliness matter—especially for new or older users reentering cannabis culture.-Design-forward brands are reshaping the traditionally male-dominated cannabis tech space.-Flower rituals still hold power, but smoother and subtler methods are expanding the definition of social smoking.-Terpenes, tech, and intention are changing how women explore the plant.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/high-tech-weed-for-modern-smokersHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

86. How Cannabis Design Transforms Psychedelic Spaces and ToolsWhat does it mean to design a high? In this first episode of a two-part series, April Pride sits down with Claire Sausen, the writer behind High Design on Substack, to explore the evolving world of cannabis design. From ashtrays as status symbols to bongs with psychological intent, Claire shares how form, function, and cultural nuance intersect to shape our altered states. Whether you’re navigating sobriety, rethinking your relationship with weed, or obsessed with stylish stoner gear, this episode dives into the future of cannabis rituals—and how women are reclaiming it. Claire also shares her unconventional path from lobbying with NORML to ghostwriting for a global cannabis architecture firm, and eventually launching her own creative practice. It's part memoir, part manifesto—and all about designing with intention.🔵 Key Takeaways-Cannabis design is more than aesthetic—it's about intention, function, and emotional resonance.-Claire’s journey spans NORML, High Times, and a cannabis architecture firm before launching High Design.-Functional weed products, like covered ashtrays and lighter cases, reveal how deeply behavior shapes design.-Cannabis design often reflects and reinforces gentrification—especially when it excludes women and people of color.-There’s a growing need for psychedelic and cannabis tools made with empathy and real-world use in mind.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/how-cannabis-design-shapes-altered-statesHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

85. From Fame to Fatherhood: Adrian Grenier on Psychedelics and ParentingHow do psychedelics influence how we show up as parents, partners, and people? In this episode, April Pride visits Adrian Grenier at his Texas ranch during SXSW to talk about identity, intention, and healing across generations. Known for his Hollywood fame, Grenier reveals the more grounded mission he’s embraced: building a sanctuary for his son—and for himself. From his first ayahuasca journey to the parenting lessons no one teaches, Adrian opens up about masculinity, midlife growth, and what it means to raise a child differently than you were raised.🔵 Key Takeaways-Adrian’s journey with psychedelics moved from escape and creativity to deep emotional integration and healing.-His current mission is creating a safe, nurturing home for his wife and son—a response to his own fatherless upbringing.-MDMA helped open his heart in intimate relationships and supported deeper compassion and connection.-Texas, especially Austin, offers unexpected openness to psychedelic healing, especially when framed through religious or family values.-Raising children on the land—not in classrooms—can encourage curiosity, presence, and emotional resilience.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/adrian-grenier-psychedelics-parentingHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

84. MDMA for Connection & Healing: A Guide to the Love DrugIn this Valentine’s Day edition, April Pride explores MDMA’s unique ability to unlock empathy, boost connection, and dissolve emotional barriers. Once known as Ecstasy, MDMA has a rich history of therapeutic use before its clubland fame and eventual classification as a Schedule I substance. April reflects on her favorite entheogen, shares listener stories, trip tips, and personal insights on why MDMA may be the best place to start your psychedelic journey. This episode includes a crash course in safe dosing, duration, and what makes MDMA such a powerful ally for healing—and love.🔵 Key Takeaways-MDMA was first synthesized in 1912 and became popular in therapy before being banned in 1985.-It’s not a psychedelic but an empathogen, promoting emotional openness and connection.-Typical doses range from 80–125 mg, but always test and start with half.-Effects include heightened mood, empathy, and warmth—but can also affect body temperature.-MDMA is resurging in therapeutic contexts, especially for PTSD and trauma work.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/mdma-connection-healingHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

83. From Film to Full Spectrum: Stephanie Wang’s Journey with Kanna Plant MedicineHow do you build a brand around a South African plant most people have never heard of—without losing its soul? In this episode, April Pride reconnects with Stephanie Wang, founder and CEO of KA!, a company producing empathogenic tinctures and gummies made from Kanna. Stephanie shares how a heart-blasting first journey changed her life, how colonialism disrupted indigenous connection to Kanna, and why commercialization requires not just good intentions—but deep inquiry. You’ll also hear about her work at The Alchemist Kitchen, the soul of KA!’s design, and how KA! sources with reverence from Khoi and San communities. If you’re curious about psychedelic alternatives, ethical sourcing, or how to live a heart-led life—this one’s for you.🔵 Key Takeaways-Kanna is a non-addictive, legal empathogen that promotes presence, peace, and heart-opening states.-Stephanie Wang's journey with Kanna began with a profound emotional breakthrough that sparked her career pivot.-KA! sources directly from South African stewards and reinvests into Khoi and San communities.-Commercializing plant medicine ethically means navigating colonial history, cultural gaps, and giving back with integrity.-KA!’s mission is to restore full-spectrum aliveness—not bypassing grief or rage, but embracing the entire human experience.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/kanna-plant-medicine-part-2Hosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

82. CBD for Sleep Support: What Actually Works for Women 40+Can CBD really help you sleep—or is it just hype? In this episode, April Pride takes a science-backed and story-driven look at CBD for sleep support, breaking down what research and real women say actually helps them fall—and stay—asleep. From full-spectrum tinctures to targeted product picks, you’ll learn the difference between CBD, THC, and CBN for sleep. April shares insights from her dad’s cannabis routine, interviews with female founders, and a hot list of strains and boosters that help you unwind without grogginess. Whether you’re struggling with perimenopause, racing thoughts, or 3am wakeups, this episode offers tangible tools for deeper rest and daily balance.🔵 Key Takeaways-CBD helps regulate your sleep-wake cycle, but THC is what puts you to sleep fast.-For best results, use a product with both CBD and THC to support all stages of rest.-Tinctures and full-spectrum products offer better absorption and longer-lasting effects.-Herbal and hemp-based blends like Blue Lotus or kin slips add a gentle, non-psychoactive boost.-Quality sleep improves mood, memory, and resilience—especially in midlife.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/cbd-for-sleep-supportHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

BONUS. Microdosing for the Heart: How Kana Builds Daily ConnectionIn this episode, host April Pride sits down with Stephanie Wang, founder and CEO of Ka Empathogenics, to talk about microdosing Kana—a psychoactive, non-psychedelic plant medicine that’s quickly gaining attention for its heart-opening effects. If you’re looking for an accessible way to integrate plant medicine into daily life, Kana might be your new ally. Stephanie shares how Ka products offer a grounded, euphoric alternative to traditional stimulants and SSRIs—and why the future of emotional wellness starts with connection, not control. Expect practical insights, personal stories, and a radically refreshing take on microdosing that centers subtlety, presence, and ritual. This episode is especially for women ready to feel more and force less.🔵 Key Takeaways-Kanna is a natural empathogen—a heart-opening plant medicine that enhances connection and emotional availability without altering perception.-Unlike stimulants or psychedelics, Ka’s Kanna formula is adaptogenic, non-addictive, and supportive of daily use for mood, focus, and nervous system regulation.-A 30-day microdosing journey helps users build deeper self-awareness, emotional resilience, and healthier habits.-Taking Kanna with intention—through journaling or morning ritual—amplifies its integrative benefits, especially for those healing from isolation or burnout.-Ka Empathogenics offers guided programs and a journal to support consistent, mindful use of the supplement.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/kanna-plant-medicine-1Hosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

81. CBD for Inflammation: Why It Works and How Women Use ItWhat if your supplement routine could ease pain, reset your nervous system, and help you stay calm—without getting high? On this episode, host April Pride dives into CBD for inflammation with clinical insight, firsthand stories, and a sharp look at the cannabis industry's shift toward wellness. You'll learn how CBD helps with chronic pain, why inflammation is often overlooked in women’s health, and how even top athletes like UFC’s Michelle Waterson use it to recover and rebalance. Joined by cannabis physician Dr. Jessica Knox, April unpacks the endocannabinoid system and how CBD works differently from THC. Whether you're new to CBD or ready to rethink your current dosage, this episode offers grounded, science-backed guidance for women navigating midlife transitions.🔵 Key Takeaways-CBD for inflammation needs higher doses than most products recommend—200–400mg is closer to effective.-UFC fighter Michelle Waterson uses CBD like a supplement: for muscle recovery, nervous system regulation, and focus.-The endocannabinoid system helps the body maintain balance, and CBD supports its function under stress, aging, and poor diet.-Topicals and tinctures work differently—what you choose depends on your pain type and lifestyle.-CBD can reduce reliance on opioids and improve quality of life for caregivers, athletes, and everyday women.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/cbd-for-inflammationHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

80. How to Dose Psilocybin Mushrooms: From Micro to Museum to MacrodoseHow much psilocybin is too much? How do you know if Golden Teacher or Albino Penis Envy is right for your journey? In this episode, April Pride tackles one of the most common—and misunderstood—questions in the psychedelic space: “What dose should I take?” Drawing from lived experiences, expert advice, and a clear-eyed look at mushroom potency, this episode is a smart, irreverent guide to navigating your dose based on intention, strain, and context. Whether you're microdosing for creativity, planning a weekend trip, or exploring ego dissolution, April helps listeners calibrate safely and intentionally—without getting kicked out of a museum.🔵 Key Takeaways-There’s no “right” dose—only the right dose for your intention. A microdose, museum dose, and ego-dissolving macrodose all serve different purposes.-Strain matters. Golden Teacher is a great entry point; Albino Penis Envy is up to 4x more potent and better for seasoned trippers.-Body weight doesn’t determine dose. Fixed doses deliver consistent results across body types, according to new research.-Psilocybin potency peaks in the first 90 minutes. Use timers to dose smartly and avoid underwhelming or overwhelming experiences.-Methods matter. Lemon tekking and tea each change the onset and intensity—choose based on how fast or slow you want to go.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psilocybin-mushroom-dosing-101Hosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

79. Albino Penis Envy Mushrooms: A Potent Strain for the Bold PsychonautWhat makes Albino Penis Envy mushrooms (APE) so powerful—and why do psychonauts and facilitators alike treat them with reverence? In this episode, April Pride breaks down the myth, potency, and practical wisdom behind one of the most infamous psilocybin strains. From trip settings to dose adjustments, she shares personal notes, expert-backed protocol tips, and what happened when four women at a Seattle Q&A confessed to unexpectedly intense experiences—all traced back to APE. Whether you’re considering whole fruit bodies or curious about microdosing caramels, this guide helps you trip smarter and safer. Expect lived experience, humor, and no-fluff advice.🔵 Key Takeaways-Albino Penis Envy (APE) is 3–4x more potent than other Psilocybe cubensis strains and should be approached with caution.-Timing your trip with ovulation may enhance the experience, especially for women.-APE is ideal for “museum doses” (250–500mg), but not recommended for microdosing beginners.-Alcohol and psilocybin don’t mix well—especially with potent strains like APE.-Trip setting, trust, and emotional readiness are critical—especially with strains that amplify both visuals and vulnerability.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/albino-penis-envy-mushroom-strain-guideHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

BONUS. How Psychedelics Are Redefining Purpose-Driven CareersIf you're mid-career and mid-transition, you're not alone—and you’re not late. In fact, you're right on time. According to a new report from Psychedelics Today, purpose-driven psychedelic careers are not only trending, they're transforming what professional success looks like. In this bonus episode, April Pride interviews David Drapkin, Director of Education at Psychedelics Today and lead on their Vital certification program. The conversation unpacks why people—especially women—are entering the psychedelic space, what kind of work they’re doing, and why almost no one is doing it for the money. Nearly 98% of Vital graduates say financial gain is not their motivator. Instead, they’re choosing healing, service, and a new kind of career alignment—especially women in midlife. Whether you're a therapist, educator, or entrepreneur, this episode offers an inside look at how psychedelics are creating pathways to personal and professional renewal. 🔵 Key Takeaways-Purpose, not profit: 98.3% of graduates said financial gain was not their main reason for enrolling in Vital’s psychedelic integration training. -Personal experience fuels career change. 87% had transformative healing experiences that sparked their shift into the psychedelic workforce. -Women are leading. Two-thirds of Vital students identify as women—many mid-career, seeking more aligned and integrative work. -Roles go beyond facilitation. Vital grads are working in biotech, media, policy, education, and finance, expanding what purpose-driven psychedelic careers can look like. -Community and collaboration matter. From underground facilitators to licensed therapists, new legal and ethical models are forming through creative partnerships. Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psychedelic-careers-with-purposeHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

78. Golden Teacher Mushrooms: The Beginner’s Psychedelic AllyHow does a mushroom become the most beloved beginner trip of all time? In this episode, April Pride wraps up her mini-series on psilocybin mushroom varieties with the golden, glowing favorite: Golden Teacher. April explains why this strain is the “Fisher-Price My First Mushroom” of the psychedelic world. From potency and visuals to spiritual insights and microdosing potential, you’ll learn why GT continues to be a trusted choice. Plus, trip tips for new psychonauts and how to get started with whole fruit bodies, caramels, or microdose offerings from Of Like Minds.🔵 Key Takeaways-Golden Teacher mushrooms are ideal for first-time users due to their low potency and short trip duration.-Effects include mild visuals, emotional clarity, and spiritual insights—often described as gentle but profound.-Whole fruit bodies offer the purest form of psilocybin; edibles and microdose options also available.-Set and setting matter: plan your dose, environment, and mindset with care for a safe experience.-The GT strain is easy to cultivate and consistent in effect, making it a staple for psychedelic exploration.Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/golden-teacher-mushrooms-beginnersHosted by April PrideSign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠youtube.com/@getsetset⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@getsetset Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe