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PODCAST · science

The Long Run with Luke Timmerman

"The Long Run"Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina and resilience to achieve something meaningful. Biotech’s relationship with the society that sustains it has never been more tenuous. Join host Luke Timmerman for in-depth, thought-provoking conversations with biotech newsmakers pursuing these great opportunities of the 21st century.

  1. 200

    Ep202: Becky Pferdehirt on Reimagining Science for the AI Era

    Becky Pferdehirt, CEO of Emeryville, CA-based Radial, the life sciences unit of Astera Institute, on reimagining biology to take advantage of advances in AI.

  2. 199

    Ep201: Jeremy Levin on Biotech in the Balance

    Jeremy Levin, executive chair of Ovid Therapeutics, discusses his new book "Biotech in the Balance: Saving a Strategic Industry in an Age of Distrust."

  3. 198

    Ep200: Richard Pops Reflects on a 35-Year Career in Biotech

    Alkermes CEO Richard Pops reflects on his 35-year career leading the company and its new opportunity in orexin biology for sleep disorders and more neurological conditions.

  4. 197

    Ep199: Martin Burke on Making Small Molecule Medicines for the AI Era

    Marty Burke, a professor of chemistry at the University of Illinois and co-founder of Excelsior Sciences, on making small molecule synthesis more automated for AI.

  5. 196

    Ep198: Abbas Kazimi on Computation and Culture for Drug Discovery

    Abbas Kazimi, CEO of Boston-based Nimbus Therapeutics, on computation and culture for drug discovery.

  6. 195

    Ep197: Viswa Colluru on Discovering Drugs Inspired by Mother Nature

    Viswa Colluru, founder and CEO of Boulder, Colo.-based Enveda, on drug discovery with a chemistry platform inspired by natural products.

  7. 194

    Ep196: Otello Stampacchia on Europe's Biotech Crisis

    Otello Stampacchia, founder and managing director of Omega Funds, on attempting to reform Europe's biotech investment climate.

  8. 193

    Ep195: Ken Song on T-cell Engagers for Autoimmune Diseases

    Ken Song, CEO of San Diego-based Candid Therapeutics, on developing bispecific T-cell engaging antibodies for autoimmune disease.

  9. 192

    Ep194: Ansu Satpathy on Cancer and Autoimmune Drug Discovery

    Ep194: Ansu Satpathy on Cancer and Autoimmune Drug Discovery by Timmerman Report

  10. 191

    Ep193: Ron Renaud on Helping People Lose Weight With GLP-1 Medicines

    Ron Renaud, CEO of Waltham, Mass.-based Kailera Therapeutics, on developing GLP-1 based medicines to help people lose weight and live healthier lives.

  11. 190

    Ep192: Kate Haviland on Following the Science to Precision Immunology

    Kate Haviland, former CEO of Blueprint Medicines, on how the company transitioned to a precision immunology company and was acquired by Sanofi for $9.5 billion.

  12. 189

    Ep191: Emily Conley on Small Molecules to Correct a Rare Kidney Disease

    Emily Conley, CEO of Berkeley, CA-based Renasant Bio, on developing small molecule correctors and potentiators for autosomal dominant polycystic kidney disease (ADPKD).

  13. 188

    Ep190: Neil Kumar on Building a Rare Disease Drug Company

    Neil Kumar is founder and CEO of Palo Alto, Calif.-based BridgeBio Pharma, a rare disease drug developer.

  14. 187

    Ep189: Marc Tessier-Lavigne on Reinventing Drug Discovery with AI

    Marc Tessier-Lavigne, CEO of South San Francisco-based Xaira Therapeutics, on reinventing drug discovery with AI.

  15. 186

    Ep188: Art Krieg on Innate Immune System Activators for Cancer

    Art Krieg, founder and CEO of Zola Therapeutics, on developing innate immune system activators for cancer.

  16. 185

    Ep187: Eric Fischer on Creating a New Class of Medicines

    Eric Fischer, a professor at Dana-Farber Cancer Institute, on creating a new class medicines -- targeted protein degraders.

  17. 184

    Ep186: Bruce Levine & Mags McCarthy on a Song About Science and Hope

    Bruce Levine, a CAR-T cell therapy researcher at the University of Pennsylvania, and Mags McCarthy, a country music star, discuss their new song about science and hope for cancer patients.

  18. 183

    Ep185: Dr. Lachelle Weeks on Predicting Leukemia Risk At Scale

    Dr. Lachelle Weeks is a physician-scientist at Dana-Farber Cancer Institute working on a project to predict leukemia risk based on widely available blood samples.

  19. 182

    Ep184: Jen Adair on Affordable, Accessible Gene & Cell Therapies

    Jen Adair, professor and associate director of the Horae Gene Therapy Center at the University of Massachusetts Chan Medical School, on creating more affordable and accessible cell and gene therapies.

  20. 181

    Ep183: Sabah Oney on CAR-T Cells Against Solid Tumors

    Sabah Oney, CEO of Philadelphia and San Francisco-based Dispatch Biotherapeutics, on engineering CAR-T cells that can kill solid tumors.

  21. 180

    Ep182: Andy Rachleff & Yung Lie on Creative Ways to Back Science

    Andy Rachleff and Yung Lie, board chair and CEO of Damon Runyon Cancer Research Foundation, on creative ways to support science amid budget cuts.

  22. 179

    Ep181: Claire Mazumdar on a Two-Pronged Attack Against Cancer

    Claire Mazumdar, CEO of Boston-based Bicara Therapeutics, on developing a bifunctional antibody for head and neck cancer.

  23. 178

    Ep180: John Rinn on Discovering Drugs Based on Long Non-Coding RNA

    John Rinn, professor at the University of Colorado and co-founder of Lincswitch Therapeutics, on exploring long non-coding RNA.

  24. 177

    Ep179: Ethan Weiss & Josh Lehrer on a New Idea for Cardiovascular Disease & Diabetes

    Marea Therapeutics CEO Josh Lehrer and CSO Ethan Weiss on a new angle of attack against cardiovascular disease and diabetes.

  25. 176

    Ep178: Peyton Greenside on ML-Guided Biologics Discovery

    Peyton Greenside, co-founder and CEO of BigHat Biosciences, on machine-learning guided biologic drug discovery.

  26. 175

    Ep177: Kevin Parker on Finding Cancer Drug Targets

    Kevin Parker, CEO of Cartography Biosciences, on finding new cancer drug targets.

  27. 174

    Ep176: David Roblin on Building a TechBio Company

    David Roblin, CEO of London-based Relation Therapeutics, on building a techbio discovery company.

  28. 173

    Ep175: Andy Scharenberg on in vivo CAR-T cell therapies

    Andy Scharenberg, CEO of Seattle-based Umoja Biopharma, on developing in vivo CAR-T cell therapies.

  29. 172

    Ep174: Najat Khan on the TechBio Movement

    Najat Khan, chief R&D and chief commercial officer of Recursion, on using technology to improve drug discovery.

  30. 171

    Ep173: Robert Blum on Building a Fully Integrated Biopharma For Muscle Disorders

    Robert Blum, CEO of South San Francisco-based Cytokinetics, on building a fully integrated biopharma to treat muscle disorders.

  31. 170

    Ep172: Mostafa Ronaghi on Studying Live Cells at Scale

    Mostafa Ronaghi, co-founder and executive board member of Cellanome, on developing technology to look at live cells and cellular interactions at scale.

  32. 169

    Ep171: Ram Aiyar on RNA Editing Medicines

    Ram Aiyar, CEO of Cambridge, Mass.-based Korro Bio, on RNA editing medicines.

  33. 168

    Ep170: David Schenkein on Investing in the Future of Biotech

    David Schenkein, general partner at GV, on investing in the future of biotech.

  34. 167

    Ep169: Kevin Fitzgerald on the Past & Future of RNAi Medicines

    Alnylam Pharmaceuticals chief scientific officer Kevin Fitzgerald on the past, present & future of RNA interference medicines.

  35. 166

    Ep168: Jonathan Bricker on How to Quit Smoking & Prevent Cancer

    Jonathan Bricker, professor in the cancer prevention program at Fred Hutchinson Cancer Center, on how to quit smoking with help from tech and biotech tools.

  36. 165

    Ep167: Leslie Williams on transfer RNA therapies

    Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.

  37. 164

    Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity

    Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.

  38. 163

    Ep165: Zach Hornby on Tackling Cancer Drug Resistance

    Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.

  39. 162

    Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients

    Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.

  40. 161

    Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases

    Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.

  41. 160

    Ep162: Sean McClain on AI for Biologic Drug Discovery

    Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.

  42. 159

    Ep161: Jeff Stein on a Long-Lasting Flu Drug

    Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.

  43. 158

    Ep160: Abe Ceesay on Precision Neuroscience

    Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.

  44. 157

    Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease

    Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.

  45. 156

    Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery

    David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.

  46. 155

    Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery

    Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.

  47. 154

    Ep156: David Liu on New Tools and Techniques for Biology

    David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.

  48. 153

    Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's

    Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.

  49. 152

    Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer

    Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.

  50. 151

    Ep153: Rick Young on Studying Gene Expression for Drug Discovery

    Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.

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ABOUT THIS SHOW

"The Long Run"Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina and resilience to achieve something meaningful. Biotech’s relationship with the society that sustains it has never been more tenuous. Join host Luke Timmerman for in-depth, thought-provoking conversations with biotech newsmakers pursuing these great opportunities of the 21st century.

HOSTED BY

Timmerman Report

Produced by The Long Run with Luke Timmerman

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How many episodes does The Long Run with Luke Timmerman have?

The Long Run with Luke Timmerman currently has 50 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.

What is The Long Run with Luke Timmerman about?

"The Long Run"Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and...

How often does The Long Run with Luke Timmerman release new episodes?

The Long Run with Luke Timmerman has 50 episodes. Check the episode list to see recent publication dates and frequency.

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The Long Run with Luke Timmerman is created and hosted by Timmerman Report.
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