The Popkin Method

Welcome back to The Popkin Method Podcast, where we break down the science of health, longevity, performance, weight loss, and healthy aging into simple, actionable principles. In this special Q&A episode, Dr. Matthew Popkin answers your most pressing questions on topics ranging from the most effective supplements for overall wellness and weight loss, the truth about sunscreen ingredients, and practical strategies for healthier skin, to proven lifestyle methods for managing blood pressure and reducing Alzheimer’s risk. We’ll dive into trending topics like peptides, separating fact from fiction when it comes to health advice on social media, and the latest insights on GLP-1 medications. As always, our focus is on building a solid foundation - sleep, nutrition, exercise, stress management, and smart supplementation to help you make informed choices and achieve sustainable results. Get ready for a fact-filled episode tailored to the real-world issues that matter most to you!Timestamps:00:00 Importance of gut health and magnesium07:53 Meeting Protein Goals with Supplements13:30 Using sunscreen with glycolic acid18:49 Daily walk and magnesium benefits26:09 Risks of Buying Peptides Online32:55 GLP1 medications and cancer research35:51 GLP1 meds and cancer research43:48 Dietary indiscretion and weight loss challenges44:38 Understanding metabolic blocks and solutions53:22 Managing GLP1 side effects56:24 Adjusting tirzepatide dosage and timing01:02:54 How to connect with Dr. PopkinYou can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected] Website - https://thepopkinmethod.com/Matthew C. Popkin, M.D. - https://thepopkinmethod.com/aboutPodcast Partner - TopHealth - https://tophealth.care/“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome back to The Popkin Method, where we connect symptoms to science, and science to solutions. In today’s episode, we're tackling one of the biggest blind spots in modern medicine: perimenopause and menopause. Millions of women are told their labs are normal while silently struggling with fatigue, anxiety, weight gain, sleep disruption, and a loss of vitality. But what if these symptoms aren’t random? What if they’re actually signals from your body?Dr. Matthew C. Popkin breaks down the complex physiologic transition of midlife hormonal change and reveals how the Popkin Method offers a systems-based, whole-body approach. We’ll dive into lifestyle medicine, nutrition, exercise, strategic supplementation, hormone modulation, peptides, regenerative medicine, and the science of longevity. If you’ve ever felt dismissed or misunderstood during this phase of life, or you want a better strategy than band-aid solutions and social media fads, this episode is for you. Let’s get started and redefine what thriving through menopause can look like.Timestamps:00:00 Understanding menopause and the Popkin method06:07 Weight gain frustrations and body changes06:57 Menopause and weight gain issues12:28 Diet tips for maintaining muscle16:06 Choosing quality supplements19:15 Importance of individualized hormone therapy22:00 Importance of Testosterone in Women26:44 Testosterone therapy options for women27:47 Testosterone treatment methods and issues31:29 Benefits of Testosterone Therapy33:57 Testosterone and breast cancer risk37:47 Testosterone therapy side effects42:33 Discussing peptide treatments and benefits44:47 Discussing GLP-1 medications usage48:01 Discussing regenerative medicine basics52:07 Discussing effective menopause treatments54:22 Discussing women's health and longevityYou can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected] Website - https://thepopkinmethod.com/Matthew C. Popkin, M.D. - https://thepopkinmethod.com/aboutPodcast Partner - TopHealth - https://tophealth.care/“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome to The Popkin Method, where we cut through the noise of miracle weight loss solutions and trendy shortcuts dominating social media and advertising today. In this episode, Dr. Matthew C. Popkin takes a deep, clinical dive into GLP-1-based therapies like semaglutide and tirzepatide, some of the most talked-about tools in modern medicine. But here’s the catch: these medications aren’t magic fixes. Instead, Dr. Matthew C. Popkin unpacks the importance of a comprehensive, sequenced approach that prioritizes lifestyle optimization, strategic nutrition, resistance-based training, and targeted supplementation before even considering medication.We’ll explore why so many struggle to keep weight off after stopping these peptides, why even lean individuals can battle insulin resistance, and how stacking the right peptides with solid foundational habits creates sustainable results. This isn’t about chasing the next health trend, it’s about reclaiming control of your physiology and building a system that actually works for the long-term. Let’s get into it.Timestamps:00:00 Success with GLP1 weight loss peptides03:58 Critiquing wellness influencer marketing10:22 Navigating modern marketing challenges11:57 Supervised weight loss and lifestyle changes14:42 Understanding Skinny Fat and Metabolic Health19:29 Prioritize fiber and healthy fats21:46 Spacing Protein Intake26:23 Maintaining Muscle with Diet and Exercise28:22 GLP1 therapies and liver health32:50 Prepping your body for medication34:20 GLP1 Medication Reset Protocol37:31 Peptide stacking with physician guidance40:54 Choosing the right peptides46:51 Addressing Insulin Resistance Strategies50:47 Avoiding medication dependency53:22 Understanding the Popkin Method55:04 Introduction to the Popkin MethodYou can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected] Website - https://thepopkinmethod.com/Matthew C. Popkin, M.D. - https://thepopkinmethod.com/aboutPodcast Partner - TopHealth - https://tophealth.care/“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the most misunderstood, yet critical, obstacles to lasting weight loss and wellness: fatty liver disease. Most people think of it as just a byproduct of poor diet or being overweight, but as you’ll learn today, fatty liver is actually a hidden metabolic bottleneck that could be sabotaging your best efforts to get healthy.If you’ve ever felt inexplicably stuck with your weight, tired for no clear reason, frustrated by slow progress even with medications, or overwhelmed by conflicting health advice online, this episode is for you. Dr. Matthew C. Popkin will break down what fatty liver disease really is, why it develops silently, and most importantly, how his signature four-phase Popkin Method can help you reverse it with a sustainable, physician-guided approach that goes far beyond gimmicks, fad diets, or quick fixes.We’ll cover the common symptoms, the pitfalls of “magic bullet” solutions, and exactly which steps you need to take, from food choices and sleep, to advanced therapies, to restore your liver health, unlock your metabolism, and finally achieve lasting change. Whether you’re new to The Popkin Method or following along since episode one, you’ll walk away with a clear, actionable blueprint to take control of your health.Ready to cut through the noise? Let’s dive into the truth about fatty liver disease and discover how to get truly unstuck.Timestamps:00:00 Understanding fatty liver disease09:57 Understanding fatty liver and GLP1 meds14:04 Supporting fat utilization strategies19:21 Understanding fasting and diet choices25:06 Common intermittent fasting mistakes30:07 Replacing carbs with veggies and fats36:32 Anti-inflammatory foods and coffee benefits37:44 Choosing the right protein shake47:04 Trustworthy supplements for fatty liver50:05 Discussing stem cell therapies59:29 Hormone modulation with supplements01:03:48 Steps for improving liver health01:09:32 Understanding the Popkin Method01:11:14 Sharing The Popkin MethodYou can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected] Website - https://thepopkinmethod.com/Matthew C. Popkin, M.D. - https://thepopkinmethod.com/aboutPodcast Partner - TopHealth - https://tophealth.care/“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Welcome back to The Popkin Method! In this episode, Dr. Matthew C. Popkin takes us beyond the surface of anti-aging, exploring the science of aging from the inside out. We’re all familiar with visible signs like wrinkles and graying hair, but what really drives aging happens deep within our cells. Dr. Matthew C. Popkin uncovers the critical role of mitochondrial function and the powerful molecule NAD, revealing how their decline accelerates aging and chronic disease.You’ll learn why energy production at the cellular level is at the heart of longevity, how lifestyle choices like diet, sleep, and exercise can naturally support NAD, and which trendy supplements may be less effective than you think. We’ll break down The Popkin Method’s sequential, practical approach to staying young, touching on gut health, muscle preservation, cognitive function, and the science behind advanced therapies. If you’re ready to understand anti-aging on a whole new level and get real, actionable strategies to improve your healthspan, tune in now!Timestamps:00:00 How NAD affects aging04:17 Understanding mitochondria and energy production07:32 Understanding nad depletion factors10:41 Importance of muscle preservation15:29 Importance of gut health17:19 Gut health and diet impacts21:49 Morning light and sleep patterns24:33 Caloric cycling and fasting strategy27:24 Balancing healthy living with treats31:13 Understanding the epigenome and PARPs33:23 The role of NAD in DNA repair37:01 Different ways to boost NAD levels40:15 Improving brain health naturally44:20 Discussing plastics and hormone disruption49:16 Stem cell and exosome therapies51:25 Introducing the Popkin MethodYou can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at [email protected] Website - https://thepopkinmethod.com/Matthew C. Popkin, M.D. - https://thepopkinmethod.com/aboutPodcast Partner - TopHealth - https://tophealth.care/“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”