PODCAST · society
This One Time On Psychedelics
by Ryan Sprague
Welcome, fellow explorers of the infinite. If you’re here, it means you’re ready to step beyond the ordinary and into the great unfolding mystery of existence itself. Because psychedelics? They’re not just substances—they’re a doorway to a new way of seeing reality, a lens that reveals the hidden layers of reality we walk through every day. And that’s exactly what we explore here. I’m Ryan Sprague, and This One Time On Psychedelics isn’t just about trippy stories and wild journeys (though trust me, we have plenty of those). It’s about the conversations that hold the power to awaken us, to shift our consciousness, and to remind us that there is far more to this reality than meets the eye. These are the conversations that expand hearts, challenge perspectives, and guide us back to the wisdom that has always been within us. Whether through plant medicines, altered states, or the everyday magic wove
Episodes
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Ep. 213: It’s Not Goodbye, It’s See Ya Later! (feat. Rachel Varitimos)
Alrighty guys, this episode is extra special to my heart because it’s officially my last episode (for now) on this show before I transition back to the Highly Optimized podcast, my first project that was birthed in 2019 when I chose to start paving my own path, leave my job & go into the unknown....
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Ep. 212: The Trifecta Of MDMA, Psilocybin & Intramuscular Ketamine (feat. Adam Schell)
One of the main reasons I started this podcast was to showcase the stories, experiences & impact these medicines have made upon people’s lives. That being said, I still get goosebumps when I hear those stories as they remind me of the immense power that not only these medicines hold within them,...
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Ep. 211: Adventures In Decentralization & Why This Movement Excites Me SO Much (feat. Amethyst Flame)
For anyone with eyes to see, it’s no secret the world is changing at a rapid rate these days. From political hysteria, to new technology emerging almost daily, it’s safe to say that it’s easier than ever to feel overwhelmed while simultaneously doing your best to keep up. In my opinion, one of…
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Ep 210: How The 2018 Farm Bill *Accidentally* Legalized Cannabis (feat. Rand Gifford)
Every episode I do I am excited about, however, this one holds a special place in my heart for a few reasons. First, anytime I get to speak with someone who is as passionate as I am around regenerative agriculture, I geek out like a small school child. This being said, when I get to speak to...
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Ep. 209: An In Depth Look At How Astrology Has Changed My Life (feat. Rachel Varitimos)
Whenever I have the opportunity to do a podcast with the love of my life, I jump at the opportunity & this week’s episode is no different. Many of you love the episodes here & I do together & our intention with todays episode is to give you a window into our personal life, what astrological…
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Ep. 208: Psychedelic Experiences, Presence & What Really Matters In Life (feat. Seibo Shen)
One of the main reasons I love podcasting so much is, yep, you guessed it, I adore speaking, however, speaking to myself alone in a room is a little weird & definitely not the same experience as when I get to speak to others who stimulate my curiosity, peak my inspiration & remind me of how epic…
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Ep. 207: You Don’t Need A Guru: Here’s How To Heal Yourself (feat. Christopher August)
Whenever today’s guest & I get together, I know it’s going to be an epic conversation. From working together the last two years creating the Breathe With Cannabis brand that many of you have attended already, to traveling to epic places together, creating memories & more, to say I am grateful for...
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Ep. 206: Opening Up To A Brand New World Through Psychedelic Medicines (feat. Kyle Langan)
One of, if not my favorite types of stories I enjoy hearing from the psychedelic space are the stories that come from individuals who, at one point, did not resonate with psychedelic medicines at all. You guys have heard me say before & I’ll say it again that for me, I never judge anyone who is...
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Ep. 205: The Mysteries Of 12 Strand DNA Decoded (feat. Dr. Samuel Lee)
I am sure you guys know what I mean when I say that sometimes I find someone new out there in the world & just cannot get enough of their content & perspective of the world. For me, I take these types of experiences as signs. Signs that perhaps we knew each other in a previous lifetime, signs…
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Ep. 204: Utilizing Psychedelics In The Grieving Process To Heal (feat. Mia Cosco)
One of the areas within the psychedelic space that is extremely important, yet often overlooked, is the ability for these medicines to assist in the process of grief. Grief is something that all of us, no matter what background, ethnicity or age group, go through from time to time. This being…
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Ep 203: Demystifying The World Of Ayurveda (feat. Ivette Desai)
Chances are this isn’t the first time you’re hearing the term “Ayurveda”. For those of us who identify as spiritual seekers, the world of ayurveda is one we hear of often & already practice to some degree in our lives (where my shilajit lovers at?”. However, I know for me, that although I knew a...
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Ep. 202: Exploring Quantum Shifts & Synchronistic Moments (feat. Shawna Pelton)
Sometimes in life, I meet people that just feel like a breath of fresh air in my life. It’s hard to put into words what I mean by that, but for those of you who have experienced this notion, I imagine you know exactly what I mean & todays guest is a woman who I can confidently say has done that...
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Ep. 201: Journeys In Psil-osophy, Hermetics & Psychedelica (feat. Austin West)
As you guys may have heard on my episode 200 solo cast last week, my favorite part of this podcast is meeting individuals that once I meet, I truly have no idea how I’ve gone my whole life not knowing. The truth is that the relationships in our life are designed to act as mirrors, allowing us to...
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Ep. 200: What A Journey It’s Been…
Wow guys…what a journey it’s been. It’s hard to believe that this podcast is already at episode 200, but, like they say, time flies when you’re having fun. In this episode, I decided to do something I’ve only done once before & do a solo cast where you guys can hear more of how this journey has...
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Episode 199: The Psychedelic Frontier: Navigating Entrepreneurship & Safety (feat. Matthew Ritchey)
The emerging world of psychedelic medicines, accompanied by the ancillary industries associated with them, is bringing with it a LOT of opportunities. For me, being as how I grew up in the world not generally interested in most of what other people did, I have long been excited at the thought of...
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Ep. 198: Opening Up To More Magic & Purpose Through Psychedelic Medicines (feat. Sofiya Skakri)
Each time I have the opportunity to do a podcast with someone who fills my heart up with joy & inspires me to dig deeper into my mission I have a blast. This being said, todays guest on the show is a woman who although I only met recently, has become a fast friend of mine & in that, we’ve found a...
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Ep. 197: How Psychedelics, Hypnosis & Biohacking Can Help You Create The Life Of Your Dreams (feat. Elia Bean)
For any of us that love psychedelic medicines, one thing that quickly becomes apparent is their ability to rapidly transform our mental landscape, including shifting belief systems, architecting new stories for us to live life through & ultimately allowing us to wake up to the truth of who & what...
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Ep. 196: Combining The Powers Of Cannabis & Tantra (feat. Zipporah “The High Priestess” Gongora)
I am fortunate enough in my life to be able to do what I love each day of my life & a BIG part of that is the love I have for podcasting. As such, I truly love & deeply enjoy all the episodes I get to do & have a blast connecting with new people, however, some episodes just touch my heart in ways...
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Ep. 195: How Psychedelics Can Make You A Better Entrepreneur (feat. Ani Manian)
One of the things that most people who do not utilize psychedelic medicines in their life would not immediately see a link between is how psychedelics can allow us to become better business owners & leaders, however, in my opinion, these things being linked together make SO much sense, as has…
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Ep. 194: Tales From The Water Shaman Himself (feat. Samson “The Water Shaman” Luce)
You guys know that feeling you get when you meet someone who makes you feel more safe knowing they’re walking the planet the same time you are? This is the exact feeling I got when I originally met the guest for today’s episode. This man is someone who is SO full of love, joy, magic & FUN that it...
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Ep. 193: Master Your Breath, Transform Your Life (feat. Christopher August)
If there is one modality aside from psychedelic medicines that has assisted me immensely over the last decade of my life, it is breathwork. From all the varying styles available to us to the fact that no matter who we are or where we are in the world that we always have access to our breath, I...
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Ep. 192: How Psychedelics Can Help You Be A Good Steward For Planet Earth (feat. JR “The Bear” Hendry)
After many years of podcasting, coaching & otherwise talking non stop, I’ve truly come to realize, understand & appreciate the art of conversation. When I meet individuals who I can have an off the cuff, pure flow state deep dive with, my heart lights up more than almost any other scenario in…
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Ep 191: From Wall Street To Psychedelics, Spirituality & More (feat. Jason Pickard)
Every once in a while in my life, I meet someone who as soon as I meet, I wonder how in the hell I ever lived my life without them in it. Typically, these people are people that I feel an instant connection with & who, along with many other facets, really spark my curiosity, inspiration &…
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Ep. 190: The Complete Deep Dive Into Cannabis Genetics (feat. Joe Colletta & Patrick)
The world of Cannabis genetics today looks much different than it did even just 5 years ago. With more & more breeders coming forth & more strain selection than ever, I find many people are confused on how to navigate this world & be able to truly understand how to find high quality genetics....
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Ep. 189: Finding Strength, Courage & Love Through Psychedelics & Sound Healing (feat. Shelley DeMarco)
In the current psychedelic renaissance, many people who otherwise had never been interested in psychedelic medicines are now finding interest in working with them. Whether it’s through the mainstream, the self development/spiritual industries or otherwise, it’s clear that with this many people…
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Ep. 188: Why Choosing To Get Uncomfortable Equips You For Psychedelic Experiences (feat. Taylor Budd)
If there’s one thing I’ve learned in the realm of psychedelic medicines, it’s that it REALLY helps to have a solid foundation of spiritual practice before connecting with these medicines. The truth is that much of what we face in these experiences is going to be challenging & by allowing yourself...
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Ep. 187: Why Decentralization & Psychedelics Go Hand In Hand (feat. Amethyst Flame)
If you guys have been following the show for even a small amount of time now, then you already know how much I absolutely adore the idea of decentralization. I am careful to ever make anything into a “cure all”, however, for many of the issues we face as a collective today, the topic of...
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Ep. 186: Rejoining The Polarities Of The Savage & The Saint Within Men (feat. Michael Holt)
For men, one of the challenges we face is how to find balance between the polarities of the savage & the saint within us. In order to express as a truly healthy man, we require both of these polarities to be expressed within our experience of life. That being said, in the modern day world,...
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Ep. 185: The Magic Of Microdosing For Peak Performance & Health (feat. Adam Schell)
As I’ve said before on this show, one of my favorite parts of hosting this show is the ability to share the epic & awesome people I meet with each of you who tune into the show. There is nothing I like more in life than connecting with others & then connecting them with more & more people. That…
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Ep. 184: Utilizing Somatic Practices To Unlock Heaven On Earth (feat. Katherine Smailis)
When I think of all of my psychedelic experiences & the tools that have come in the most handy during these experiences, no realm comes to mind quicker than that of Somatics. Somatics, said simply, is any practice that uses the mind-body connection to help you survey your internal self & today’s...
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Ep. 183: From The Depths Of Despair To A Triumphant Return Through Psychedelics (feat. Ryan Graves)
You’ve probably heard me say before that pain in our lives can be a teacher that educates us on what is either in or out of alignment with our souls mission in life. For years, I have been fascinated by this concept because it allows pain, which is something that many of us, including myself for...
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Ep. 182: Tuning The Human Biofield & Unlocking Electric Health (feat. Eileen Day McKusick)
As you guys have all heard me say enough times by now, we really don’t need psychedelics to invoke a psychedelic experience, as all these medicines do is open us up to the true reality that is always all around us, but Is not always perceptible to us due to the human condition. Today’s guest on…
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Ep. 181: Expanding Reality To New Heights (feat. Brandon Thomas)
One of my absolute favorite parts of doing this show & podcasting overall are the incredible connections I make with like minded individuals who are also on a path to light up the world with their unique magic. When I find these people, I like to have them on the show periodically to not only...
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Ep. 180: More God, Less Dogma (feat. Mark Anthony Lord)
I feel for many of us who find our way into the realm of psychedelic medicines, that we’re “searching” for something. I know for me, I had no idea what I was searching for, yet that didn’t stop it from finding me & for me personally, what I was truly searching for was a deeper connection with…
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Ep. 179: How Viewing Life AS The Psychedelic Can Assist Us In Reaching Our Full Potential (feat. Charlie Trinh)
Sometimes when I have a guest on the show, it becomes apparent to me that we could have done 10 hours straight of talking without running out of ideas or energy. When I find guests like these, it not only fires me up because of the connection & conversation we share, but also because I am always...
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Ep.178: An End To An Upside Down World (feat. Mark Gober)
Ep.178: An End To An Upside Down World (feat. Mark Gober) I think for most of us that have found our way into the world of psychedelic medicines in the present day, that we can agree that pretty much everything in life is upside down when viewed through the lens of the mainstream narrative. From...
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Ep. 177: The Psychedelic Reality Of Web3, Blockchain & Decentralization (feat. Amethyst Flame)
A couple of the areas that I have found in the last few years that has been earth shatteringly psychedelic are those of web3, blockchain & decentralization as a whole. I feel for many of us who have found our way into psychedelic medicines, that the idea of decentralization, in which centralized...
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Ep. 176: A Great Example Of How Psychedelics Can Allow Us To Be The Change We Wish To See In The World (feat. Dr. Edith Ubuntu Chan)
For me, the “goal”, if you will, of my psychedelic experiences has always been to live in a more psychedelic daily reality through utilizing these experiences to take action on creating the life of my dreams. I feel many of us know there is more to life than what we see each day, yet, if you’re...
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Ep. 175: Generational Healing & Creating A More Beautiful World Through Self Love & Empowerment (ft. Leah Drew)
One of my favorite aspects of hosting this podcast is the opportunity to meet new people & also to feature some of my closest & dearest friends in the world as I truly believe that human connection is the most important medicine in very short supply in the world right now & my hope is that by...
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Ep. 174: The True Mysteries Of Cannabis Revealed (feat. JR “The Bear” Hindry)
It’s no mystery for any of you who have been following me for any length of time now that I am a huge proponent of the medicine of Cannabis. That being said & like I say often, even though this may be the most popular plant medicine in existence & the most widely used, I have also found that this...
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Ep. 173: Opening Up New Doorways To More Purpose Through Ayahuasca (feat. Sam Believ)
When I entered the realm of psychedelic medicines, no medicine was more popular & talked about more than that of Ayahuasca. I have been fascinated with this medicine for years in hearing so many stories & featuring so many people on the show that have had experiences with it & being as how I have...
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Ep. 172 How Early Psychedelic Experiences Can Open You Up To A Psychedelic Life (feat. Dawn Lester)
Many of us who come to the realm of psychedelic medicines innately understand that much of what we are told is true in our world is completely backwards. From medicine & healthcare, to how we grow our food, our laws, what we understand about consciousness & more, it’s clear that many of us come…
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Ep. 171: Going On The Quest To Discover The Mystery Of DMT (feat. John Chavez)
For those of us in the psychedelic space, no molecule is more popular & well known than that of DMT. This being said, for how popular this molecule is, it is shrouded in just as much mystery as it has been for millennia & in addition, many of us are unaware that we actually produce DMT…
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Episode 170: The Hero’s Journey Of Overcoming Addiction & Discovering Plant Allied Recovery (feat. Luke Storey)
For many of us who embark into the world of plant medicine, we may come from a background of addiction challenges or substance abuse in which in order to heal our addictions, we must swing the polarity to that of complete sobriety for a period of time. For some of us, that period may be the...
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Episode 169: Becoming Liberated From The Inside Out (feat. Omar Nassri)
One of my favorite aspects of the world of psychedelics are not only the stories & experiences people have had with them, but rather, what they have been able to create in their lives as a result of connecting with these medicines & doing the work to integrate them thereafter. What I have found…
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Episode 168: Allowing Psychedelics To Tap Us Back Into Who & What We Truly Are (feat. Charlie Trinh)
For me, psychedelic medicines have truly assisted me in waking up to the truth of who I am & as a result of these experiences, I have been able to find the people, places & passions that are truly meant for me & one of those individuals is todays guest on the show. We met recently at an amazing...
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Episode 167: Tapping Into The Mystical World Of The Amanita Muscaria Mushroom (feat. Christian Rasmussen)
Whether it’s in Mario, the myth of Santa Clause or various other depictions, no other mushroom is as well known & popularized as Amanita Muscaria. That being said, this mushroom has also been shrouded in mystery as other psychedelic mushrooms become more & more popular in todays world. Todays…
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Episode 166: A Tale Of Breaking Societal Patterns & Following The Call Of The Heart (feat. Cooper Montgomery)
One of the first things I noticed about Cannabis & other psychedelics when I first experienced them was their ability to open up more expanded expressions of myself. From enhanced creativity, to deeper flow states & more, it became immediately apparent to me why SO many artists find their way to...
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Episode 165: Healing & Expanding With Cannabis (feat. Alex Morningstar)
Hello & welcome every body to part 3 of our “Conscious Cannabis” series! In part one, we illuminated for each of you the differences between an unhealthy, dependent relationship with Cannabis & a healthy, conscious relationship with Cannabis & in part two, we shared the foundation for how to...
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Episode 164: Connecting With Cannabis As A Personal & Spiritual Growth Tool (feat. Alex Morningstar)
Last week on the show, we dove deep into the process of remediating dependent or dysfunctional patterns with Cannabis & this week, we’re diving even deeper. When someone is able to establish a healthy relationship with Cannabis & one that is co creative in nature, a whole new world emerges where...
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ABOUT THIS SHOW
Welcome, fellow explorers of the infinite.
If you’re here, it means you’re ready to step beyond the ordinary and into the great unfolding mystery of existence itself. Because psychedelics? They’re not just substances—they’re a doorway to a new way of seeing reality, a lens that reveals the hidden layers of reality we walk through every day. And that’s exactly what we explore here.
I’m Ryan Sprague, and This One Time On Psychedelics isn’t just about trippy stories and wild journeys (though trust me, we have plenty of those). It’s about the conversations that hold the power to awaken us, to shift our consciousness, and to remind us that there is far more to this reality than meets the eye.
These are the conversations that expand hearts, challenge perspectives, and guide us back to the wisdom that has always been within us. Whether through plant medicines, altered states, or the everyday magic wove
HOSTED BY
Ryan Sprague
CATEGORIES
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Frequently Asked Questions
How many episodes does This One Time On Psychedelics have?
This One Time On Psychedelics currently has 213 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is This One Time On Psychedelics about?
Welcome, fellow explorers of the infinite. If you’re here, it means you’re ready to step beyond the ordinary and into the great unfolding mystery of existence itself. Because psychedelics? They’re not just substances—they’re a doorway to a new way of seeing reality, a lens that reveals the hidden...
How often does This One Time On Psychedelics release new episodes?
This One Time On Psychedelics publishes regularly with 213 episodes available. Check the episode list for the typical release schedule.
Where can I listen to This One Time On Psychedelics?
You can listen to This One Time On Psychedelics on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts This One Time On Psychedelics?
This One Time On Psychedelics is created and hosted by Ryan Sprague.
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