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All Episodes

Journal of Clinical Oncology (JCO) Podcast — 462 episodes

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Title
1

Phase 2 Study of Multi-Cancer Detection from Breath Samples

2

JCO at ASCO 2026: Individualized Neoantigen Therapy Plus Pembrolizumab in Melanoma

3

JCO at ASCO 2026: Pemigatinib Phase 3 FIGHT-302 Trial in Cholangiocarcinoma

4

JCO at ASCO 2026: Individual Patient Pooled Analysis of Low-Dose Tamoxifen in DCIS

5

JCO at ASCO 2026: Neoadjuvant Sacituzumab in MIBC

6

JCO at ASCO 2026: Intravesical Recombinant BCG with Chemo-Immunotherapy in MIBC

7

Adjuvant Durvalumab and the Future of Early-Stage NSCLC

8

JCO Article Insights: LEAP-010 Study in Recurrent/Metastatic Head and Neck Cancer

9

Infections in Two Diet Strategies in HSCT and Leukemia Patients

10

JCO Article Insights: ctDNA in DLBCL - Ready for Prime Time?

11

The CISTO Study: Radical Cystectomy or Bladder-Sparing Therapy for Recurrent NMIBC

12

JCO Article Insights: Atezolizumab, Bevacizumab, and Non-Platinum Chemotherapy for PROC

13

JCO Article Insights: Ribociclib Plus Letrozole in Recurrent LGSOC: GOG 3026

14

NCI Working Group on Biochemically Recurrent Prostate Cancer

15

Association Between EOL SACT and Healthcare Utilization

16

Milan Consensus Endpoints for Bladder Preservation in MIBC

17

JCO at 2025 ASH: Pirtobrutinib in Untreated CLL

18

JCO at ASH 2025: A New Validated Staging System for AL Amyloidosis: AL-ISS

19

JCO Article Insights: Simultaneous Durvalumab and CRT in Unresectable Stage III NSCLC

20

Health Outcomes in Older Childhood Cancer Survivors

21

Long-Term Remission After Cilta-cel in Patients With RRMM

22

JCO Article Insights: Xevinapant Plus Chemoradiotherapy in Unresected LA SCCHN

23

Income Among Adolescents and Young Adults Surviving Cancer

24

JCO Article Insights: Phase I DLL3/CD3 T-Cell Engager in DLL3-Positive SCLC or NECs

25

TTFields in Locally Advanced Pancreatic Adenocarcinoma

26

JCO at WCLC: Multinational Pivotal Study of Sunvozertinib in Exon20ins NSCLC

27

Racial and Ethnic Disparities Among Medicare Beneficiaries

28

JCO Article Insights: Lymph Node Dissection for Lung Cancer

29

JCO Article Insights: IMS-IMWG Consensus on High-Risk Multiple Myeloma

30

JCO Article Insights: Pooled Taletrectinib Efficacy and Safety

31

JCO at ASCO Annual Meeting: Neoadjuvant Osimertinib for Resectable EGFR-Mutated NSCLC

32

JCO at ASCO Annual Meeting: Use of Low-Value Cancer Treatments in Medicare

33

JCO at ASCO Annual Meeting: Avelumab Plus Cetuximab vs. Avelumab in Advanced cSCC

34

JCO at ASCO Annual Meeting: TTFields in Locally Advanced Pancreatic Adenocarcinoma

35

JCO at ASCO Annual Meeting: Lenvatinib Plus Pembrolizumab and Chemotherapy in Gastric Cancer

36

JCO Article Insights: Double Hit Myeloma Correlates With Adverse Patient Outcome

37

Pembrolizumab and Bevacizumab for Melanoma Brain Metastases

38

JCO Article Insights: ESPAC4 Long-Term Follow-Up in Pancreatic Cancer

39

Longitudinal Results from the Nationwide Just ASK Initiative to Promote Routine Smoking Assessment

40

JCO Article Insights: Smoking Assessment

41

Botensilimab Plus Balstilimab in Advanced Sarcomas

42

JCO Article Insights: Long-Term Outcome of Neoadjuvant Chemotherapy for Rectal Cancer

43

High Omega-3, Low Omega-6 Diet with Fish Oil and Prostate Cancer

44

JCO Article Insights: TROPION-Lung01 Dato-DXd in NSCLC

45

Air Pollution and Breast Cancer Incidence

46

JCO Article Insights: Adoption of Capivasertib in Metastatic Hormone Receptor–Positive, HER2-Negative Breast Cancer – Efficacy, Toxicity and Treatment Sequencing

47

Overcoming Barriers to Make Patient-Partnered Research a Reality

48

JCO Article Insights: Nivolumab + Relatlimab v Nivolumab + Ipilimumab in Melanoma

49

Quality of Treatment Selection

50

JCO Article Insights: HLA-Mismatched Unrelated Donor HCT With PTCy

51

Adjuvant Pembrolizumab for High-Risk, dMMR Endometrial Cancer

52

Combining Response and Toxicity Data to Implement Project Optimus

53

CBT-I for Cancer-Related Cognitive Impairment

54

JCO Article Insights: Assisted Reproduction in Breast Cancer Patients

55

Multi-Cancer Early Detection Testing for High-Risk Patients

56

JCO Article Insights: Back to the Drawing Board: Overcoming Resistance to PD-1 Blockade

57

Functional Disability Among US Cancer Survivors

58

CAR T-Cell Therapy for Richter's Transformation

59

EAZ171: Predictors of TIPN in Black Women with Breast Cancer

60

JCO Article Insights: Final Analysis of the Ro-CHOP Trial

61

Methylphenidate for Fatigue in Advanced Cancer

62

Introducing JCO Oncology Advances with Dr. Jonathan Friedberg and Dr. Pamela Kunz

63

JCO Article Insights: Atezolizumab Plus Bevacizumab, Chemotherapy in EGFR, ALK NSCLC

64

Commonly Held Beliefs About Cancer Survivorship

65

JCO Article Insights: Long Term Follow Up of the RESORT (E4402) and LYSA Study

66

Pembrolizumab in Patients With Advanced Cancers With HTMB

67

JCO Article Insights: Axillary Soft Tissue Involvement and Breast Cancer Prognosis

68

Omission of Radiotherapy after Breast-Conserving Surgery

69

Costs of Cancer Prevention in CDH1 Variant Carriers

70

JCO Article Insights: Low and Moderate Grade Adverse Events and the Patient Experience in Clinical Trials

71

Debunking Sex and Disentangling Gender From Oncology

72

Germline EGFR Mutations and Familial Lung Cancer

73

JCO Article Insights: DYPD-Guided Dose Individualization and Survival Outcomes

74

Negative Impact of Prior Authorization on Patients with Cancer

75

Role of Molecular Classification in Predicting Response to Radiation in Early Endometrial Cancer

76

JCO Article Insights: Impact of Physical Activity on Mortality and of BMI on Treatment-Related Adverse Events

77

Durvalumab Plus Carboplatin/Paclitaxel Followed by Maintenance Durvalumab With or Without Olaparib as First-Line Treatment for Advanced Endometrial Cancer: The Phase III DUO-E Trial

78

JCO Article Insights: Safety and efficacy of a Novel ADC Targeting TROP-2 in Metastatic Non-Small Cell Lung Cancer (NSCLC)

79

Economic Evaluation of a Non-Medical Financial Assistance Program on Missed Treatment Appointments Among Adults With Cancer

80

Disparities in End-of-Life Cancer Care

81

Advance Care Planning in Adolescents and Young Adults with Cancer

82

JCO Article Insights: Improving Lung Cancer Screening Using Blood-Based Biomarkers

83

Impact of Smoking Cessation on Mortality From Kidney Cancer

84

HER3-DXd in EGFR-Mutated NSCLC: HERTHENA-Lung01

85

JCO Article Insights: Introducing The Childhood Cancer Data Initiative

86

Impact of Heatwaves on the Care of Patients With Cancer

87

JCO Article Insights: Immunotherapy in People Living with HIV and Cancer

88

Racial/Ethnic Differences Discovered in Multigene Germline Testing of Early-Onset Colorectal Cancer

89

JCO Article Insights: Two New Prediction Models for Risk of Venous Thromboembolism in Cancer Patients

90

Olanzapine for Chemotherapy-Related Anorexia

91

PROSPECT Trial (Alliance N1048): PROs During and After Treatment for Locally Advanced Rectal Cancer

92

JCO Article Insights: Smoking Cessation for Patients with Cancer

93

JCO Article Insights: Use of Independently-Assessed vs Investigator-Assessed DFS in the APACT Trial

94

Peritumoral Anesthetic Infiltration Impacts Survival in Early Breast Cancer

95

Intensive Caring: Reminding Patients They Matter

96

Barriers to Clinical Trial Participation for Transgender People

97

JCO Article Insights: Trial Update on Development of Children After Maternal Cancer During Pregnancy

98

Cancer Screening During the 2nd Year of the COVID-19 Pandemic

99

Sequencing Matters – Combination Dabrafenib/Trametinib Versus Nivolumab/Ipilimumab for Advanced BRAF-Mutant Melanoma: The DREAMseq Trial

100

JCO Article Insights: Phase III POSEIDON Clinical Trial Results

101

One-Stop-Shop Comprehensive Cancer Screening Center Focused on Asymptomatic Screening

102

Improving Transparency in Phase 1 Clinical Trials

103

JCO Article Insights: Elderly Patients Receiving Chemotherapy for Early-Stage Breast Cancer

104

Ensuring Employment After Cancer Diagnosis

105

Intersectional Maxims for a New Era in Modern Medicine

106

Does Medicare Advantage Lead to a Disadvantage for Patients Who Need Surgery for Cancer?

107

Lack of Gender Equity in Oncology Clinical Trial Advisory Board Membership

108

Universal Germline Genetic Testing in GI Malignancies

109

Light From Darkness - Navigating Postmortem Tissue Donation

110

Physical Activity Improves Survival in Colorectal Cancer

111

Food Insecurity Interventions for Cancer Survivors With Dr. Francesca Gany and Dr. Theresa Hastert

112

How to Confront Climate Change: A Framework for Change in the Operating Room and Hospital as a Whole. A Conversation with Dr. Anaeze Offodile and Dr. Elizabeth Yates

113

JCO After Hours: A Discussion With Veena Shankaran and Scott Ramsey

114

JCO After Hours: A Discussion With Virginia Sun

115

JCO After Hours: A Discussion With Antonio Di Meglio

116

JCO After Hours: A Discussion With Abby Rosenberg and Reshma Jagsi

117

JCO After Hours: A Discussion With Michael Gnant and Kathy Miller

118

JCO After Hours: A Discussion With Kirsten Beyer and Jennifer Griggs

119

Is Dose-Adjusted EPOCH-R the Optimal Treatment for Children with Primary Mediastinal B-Cell Lymphoma?

120

Steroid Dose and Taxanes

121

Commentary on GROINSS VII

122

Harnessing the Power of Registries to Understand the Impact of Treatment for Hodgkin Lymphoma on Fertility

123

Subspecialty Palliative Care Involvement May Lessen the Need for High-Intensity End-of-Life Care for Adolescents and Young Adults With Cancer

124

Can the Incorporation of Minimal Residual Disease Detection Enhance Post-CAR T Outcomes in Patients With Large B-Cell Lymphoma?

125

Moving Forward With Venetoclax-Based Combinations in Younger Adults With Acute Myeloid Leukemia

126

A Deep Dive Into HLA Typing For Unrelated Donor Hematopoietic Cell Transplantation

127

PENELOPE-B: Exploration of CDK4/6 Inhibition in the Adjuvant Setting

128

ctDNA in DLBCL: A Blueprint for Better Clinical Trials?

129

How Can We Expand Eligibility Criteria for Diffuse Large B-Cell Lymphoma Clinical Trials to Serve More Patients?

130

The Pathologist, the Surgeon, and the Rare Phyllodes Tumor

131

Cancer Surgery in COVID-19-Free Facilities

132

Finding a Needle in a Haystack of Mutations: Using Whole Genome Sequencing to Identify Patients with Low-Risk Myeloma

133

Advancing Knowledge on the Use of Dexrazoxane in Children With Acute Myeloid Leukemia and Other Childhood Cancers

134

Better Diet – Fewer Side Effects?

135

Genetic Testing in Breast Cancer Patients: Striking the Balance Between Over Versus Undertesting

136

High Reward, High Toxicity: Combination Pembrolizumab and Lenvatinib in Advanced Endometrial Cancer

137

Optimizing Treatment Strategies for Germline BRCA/PALB2 Mutant Pancreatic Adenocarcinoma

138

Immune Checkpoint Inhibitor Use in Patients With Inflammatory Bowel Disease: A Closer Look

139

The High Prevalence of Exercise Intolerance in Adult Survivors of Childhood Cancer Is Predictive of All-Cause Mortality

140

Leptomeningeal Disease in EGFR-Mutated Lung Cancer: Can We Finally Define a Standard Treatment?

141

Advancing Treatment Options for Mismatch Repair-Deficient Metastatic Colorectal Cancers

142

Keeping Mycosis Fungoides in Check: A Study of Pembrolizumab for Relapsed/Refractory MF and Sezary Syndrome

143

What's in a Name? An Introductory Guide

144

Resuming Life After Cancer Therapy: Treatment-Free Survival

145

Intratumoral Immune Infiltration in Follicular Lymphoma: Novel Insights into Early Relapse and Survival

146

MYC Rearrangements in Diffuse Large B-Cell Lymphoma: Impact and Implications for Diagnostic Testing

147

Centralization of High-Risk Surgery: Real Benefits for Patients From Health Systems

148

Microsatellite Instability as a Prognostic Marker for Resectable Gastric Cancer and a Potential Biomarker for Perioperative Chemotherapy Benefit

149

Radiotherapy Dose Reduction Is Possible With Induction Chemotherapy for Pediatric Nasopharynx Cancer

150

Fine Tuning Therapy for Intermediate-Risk Neuroblastoma Using Clinical Response and Tumor Biology

151

Déjà Vu or Predicted: The Failure of Dose Adjusted EPOCH-R to Improve Outcomes in Diffuse Aggressive Lymphomas

152

Tackling Stage III EGFR Mutation-Positive Lung Cancer: Do We Really Know How?

153

The Need for Continued Vigilance in Patients with Diffuse Large B-Cell Lymphoma

154

A Second Chance at Checkpoint Inhibition After Initial Immune-Mediated Diarrhea and Colitis

155

Anticipating the Future of Hodgkin Lymphoma

156

An Advance for the Treatment of Osteosarcoma

157

The Heartbreak of Cancer Treatment: The Latest in Late Cardiac Toxicity

158

Programmed Cell Death-1 Pathway Inhibitors Enter Center Stage as First-Line Treatment of Advanced Merkel Cell Carcinoma

159

Potential for Parenthood After Childhood Cancer: Perceptions and Reality

160

How Should We Interpret Indeterminate Pulmonary Nodules at Diagnosis in Children With Rhabdomyosarcoma?

161

The End of ENDoxifen Metabolite and CYP2D6 Testing in Tamoxifen-Treated Women?

162

Less is More: Precision Surveillance Imaging for Wilms Tumor

163

How Low Can You Go? Impact of Baseline Corticosteroid Use on Immunotherapy Outcomes in Patients With Advanced Non-Small-Cell Lung Cancer

164

Expanding Treatment Options for Hormone Receptor-Positive, HER2-Positive Metastatic Breast Cancer

165

The Addition of Another Camptothecin Fails to Improve Outcomes in Patients With Intermediate-Risk Rhabdomyosarcoma

166

The Addition of IKZF1 Deletion in Risk Stratification for Children with Newly Diagnosed B-Acute Lymphoblastic Leukemia Leads to Improved Survival: Results of the Malaysia-Singapore ALL 2010 Study

167

Psychosocial Outcomes Following Contralateral Prophylactic Mastectomy: Insights and Opportunities

168

Risky Business: PD-1 Immune Checkpoint Blockade in Thymic Epithelial Neoplasms

169

Don't Treat Me Like a Child: The Intensification of Conventional Chemotherapy in Adults With Acute Lymphoblastic Leukemia

170

Multiple Myeloma Joins the Car T Race

171

Cardiotoxicity After Breast Cancer Radiotherapy: Which Part of the Heart Matters Most?

172

Should Prophylactic Cranial Irradiation Be Used in Patients with Stage III Non-Small Cell Lung Cancer?

173

The Medical Marijuana Conundrum: When Public Interest Outpaces Medical Knowledge

174

Racial Disparities in Medical Financial Hardship Among Cancer Survivors

175

Late Infectious Death: Asplenic Adult Survivors of Child Cancer

176

Extending the Reach of Targeted Therapy for Hormone Receptor-Positive Advanced Breast Cancer

177

An International Phase II Trial of Single-Agent Nivolumab for Hodgkin Lymphoma Relapsed or Refractory After Autologous Stem Cell Transplant

178

Exploring a New Delivery Model for Germline Genetic Testing for Patients With Ovarian Cancer

179

Is Earlier Treatment Better For Patients? The Case of Docetaxel in Metastatic Castration-Sensitive Prostate Cancer

180

The Decision to Image Breast Cancer Patients with Local-Regional Recurrence

181

The Importance of Reading Clinical Trial Protocols Simultaneously With Published Studies

182

Understanding the 'Value-Added' by Specialized Pediatric Palliative Care Teams in the Care of Children With Cancer at the End of Life

183

Survival Following Radiofrequency Ablation Versus Stereotactic Body Radiotherapy for Early-Stage Hepatocellular Carcinoma

184

The True Costs of the 21-Gene Assay in a Cohort of 1,000 Patients

185

Persistent Use of Opioids After Cancer Surgery

186

Discussion on the Cost–Effectiveness Analysis of the CALGB/Alliance Trial and the Use of Zoledronic Acid Generic in Women With Metastatic Breast Cancer

187

Can We Simplify the Treatment of Myelofibrosis?

188

Lessons to be Learned about the Significance of Educational Level in Adults with Acute Myeloid Leukemia

189

More Often but Not Early: Hospice Use Among Older Adults With AML

190

T-cell Therapy for Viral Infections after Stem Cell Transplant

191

Shared Risk Factors in Cancer and Cardiovascular Disease: Can We Make a Difference?

192

Should Metabolic Imaging to Assess Minimal Residual Disease (MRD) Become a Clinical Endpoint in Multiple Myeloma?

193

Considerations in Predicting Neuropsychological Outcomes in Children Treated for ALL

194

Low-Income Subsidy and Financial Barrier to Access Costly Oral Chemotherapy Drugs for Myeloma Patients Enrolled in Medicare Part D

195

Beyond the Beam: Thinking about Subsequent Malignancy Risk Outside of the Radiation Paradigm,"

196

Discussion of the SWORD-Study and Fear of Cancer Recurrence Intervention Research Randomized Controlled Trial

197

Optimizing Up-Front Therapy for Double-Hit Lymphoma

198

Chronic Conditions in Cancer Survivors

199

Do Treatment Summary Survivorship Plans Make Any Difference?

200

The Impact of Cigarette Smoking on Survival in Patients with Pancreatic Cancer

201

Better Patient-Reported Outcomes After Autologous Breast Reconstruction Compared to Implant-Based Reconstruction Study

202

Drugs Don't Work in Patients Who Don't Take Them

203

Pembrolizumab is Safe and Active in Platinum- and Cetuximab-Refractory Head and Neck Squamous Cell Carcinoma

204

Long-Term Follow-up of AF-001JP: A Phase I/II Study of Alectinib in ALK-Positive NSCLC

205

Late Relapse in Hodgkin Lymphoma Persisting Even at 20 Years: Implications for Therapeutic Intensity and Disease Biology

206

Intensification of Consolidation Therapy for Acute Myeloid Leukemia by the Addition of Clofarabine to Cytarabine Improves Relapse-Free Survival

207

Characterizing the Patterns of Clonal Evolution in Ibrutinib-Treated CLL: A Roadmap for Continued Progress

208

Prevalence of Germline Mutations in Individuals With Colorectal Cancer as Determined Using a Multi-Gene Panel Test

209

Financial Barriers to Cancer Care for Patients Obtaining Insurance on the Federal Exchange

210

Mindfulness-Based Interventions in Oncology: Not for Everyone?

211

The Impact of Oral Targeted Therapies on the Cost of Care for Patients With Chronic Lymphocytic Leukemia

212

Watching Nivolumab's Balancing Act: How Immune Activation May Affect Both Safety and Efficacy in Patients With Advanced Melanoma

213

Getting to the Heart of the Matter: Biomarkers for the Assessment of Trastuzumab-Induced Cardiac Dysfunction

214

Listen to Your Patients

215

Impact of Organizational Characteristics and Process of Care on Hospital Mortality and Resource Use in Cancer Patients Admitted to Intensive Care Units

216

Health-Related Quality of Life: Increasingly Important in the Era of Effective, Modern Myeloma Therapy

217

Chemotherapy Induced Peripheral Neuropathy: A Novel Method of Exploration

218

Changes in the Epidemiology of AIDS-Related Kaposi's Sarcoma and Lymphomas: How This Informs the Clinician

219

Implicit Racial Bias Affects Key Aspects of Physician Communication

220

Nivolumab Monotherapy is Safe and Active in Hematologic Malignancies

221

Minimizing Frailty in Cancer Survivors: A Meaningful Goal for All Ages

222

1q Gain, a Prognostic Biomarker in Nephroblastoma, and What's Next?

223

Therapy Impacts Long-Term Survival for Patients in Germany With Heritable Retinoblastoma

224

Dexamethasone and High-Dose Methotrexate in High-Risk B Cell Acute Lymphoblastic Leukemia—Where Should We Go From Here?

225

Unraveling the Significance of Mismatch Repair Deficiency in Women With Endometrioid-type Endometrial Adenocarcinoma

226

Nodal Status After Neoadjuvant Chemotherapy Determines Prognosis in Localized Gastric Cancer

227

Restrictions on Nutrition, Social Contacts, and Pets Are Not Effective Anti-Infective Measures in Children With Acute Myeloid Leukemia

228

Current Status of Supplemental Screening in Dense Breasts

229

Selective Internal Radiation Therapy for Liver-Dominant Metastatic Colorectal Cancer: Time to Put the Brakes On?

230

Prognostication Based on Site of Metastatic Disease in Castration Refractory Prostate Cancer: Implications for Patient Care and Clinical Trial Design

231

IgM-Related AL Amyloidosis: A Rare Form of a Rare Disease

232

Quality of Life: A Critical Consideration in Women Diagnosed with Ductal Carcinoma in Situ

233

Very Late Outcomes of Wilms Tumor Survivors: British Childhood Cancer Study

234

Web-Based Technology Can Improve Patient Understanding and Preparedness to Discuss Cancer Clinical Trials: One Step Towards a Goal of Increased Enrollment

235

How Should We Manage the Financial Toxicity of Cancer Treatment?

236

Prognostication in Mantle Cell Lymphoma

237

Sunbelt Melanoma Trial: A Seminal Adjuvant Interferon Trial with Long Term Results

238

Hepatocellular Carcinoma in Children and Adolescents: Time for a Strategy and a Trial

239

Clinical Drug Development for Non-Muscle-Invasive Bladder Cancer…Definitions Matter

240

Race for the Cure: How differences in Race and Ethnicity Impact the Diagnosis and Survival of T-Cell Lymphoma

241

Epidural Spinal Cord Compression: The Importance of Multi-disciplinary Treatment Planning

242

Hard to RECIST: Updating and Simplifying Primary Tumor Response Guidelines for the Revised International Neuroblastoma Response Criteria (INRC)

243

Expanding Immunotheapy Benefit in Metastatic RCC

244

A New Oncogene Target in Lung Cancer: Exon 14 Alterations in the MET Gene

245

The Evolution of the Polycythemia Vera Symptom Burden: Implications for a Changing Treatment Paradigm

246

The Emerging Role of Gallium-68 Somatostatin-Receptor PET Imaging in Neuroendocrine Tumors

247

Dexrazoxane for childhood cancer patients – ready for prime time?

248

Uterine lavage: a new approach to gynecologic cancer detection?

249

Hormonal Therapy is Out for Meningiomas: Time to Change Tactics?

250

Defining the Optimal Interval for Colonoscopic Screening in Individuals with a Family History of Colorectal Cancer

251

Using the CLIC Study of Outcome in Advanced Stages of Mycosis Fungoides and Sezary Syndrome to Guide Treatment And Clinical Research

252

Geographic Access as a Barrier to Adjuvant Chemotherapy for Patients with Stage III Colon Cancer

253

Host Factors and Lynch Syndrome Patients: Weighing Role of Obesity and Aspirin and Risk of Colorectal Cancer

254

To Stop or Not to Stop: That is the Question

255

Breast Cancer and Weight Loss: Where Do We Go from Here?

256

The Promise and the Pitfalls of Population-Wide Screening of BRCA1 and BRCA2

257

Intraperitoneal Therapy for Ovarian Cancer: No More Excuses

258

Balancing Safety and Efficacy in the Treatment Hodgkin Lymphoma: Early Discontinuation of Certain Drugs Can and Should Be Done

259

When Toxicity and Efficacy Collide

260

First Results of Euramos I and Logistics of International Collaboration for Clinical Trials of Rare Diseases

261

Treatment Advances in Local-Regionally Advanced and Stage IVB/Recurrent Cervical Cancer: Can We Agree that More Isn't Always Better?

262

Androgen Deprivation Therapy for Prostate Cancer - Friend or Foe to the Psyche?

263

Building Blocks in the Case for Adjuvant Therapy in Biliary Tract Cancers

264

Aromatase Inhibitor Arthralgias: Identification, Treatment Options and Research Perspectives

265

Deciphering the Heterogeneity Within EGFR-mutant Lung Cancer

266

Precision Immunology: The Promise of Tumor Immunotherapy for the Treatment of Cancer

267

The Importance of Discussing Genetics with Every Breast Cancer Patient

268

Hematopoietic Stem Cell Transplant for Children With Acute Lymphoblastic Leukemia at BFM Centers: Comparable Results With Matched Sibling Donors and Matched Unrelated Donors

269

Is It Biology or Brawn in Ovarian Cancer Surgery?

270

Mirror Views: Reflections of Complementary Perspectives in Patient and Clinician Toxicity Reporting

271

Dynamic Evolution of ALK Positive Non-Small Cell Lung Cancers and Management of Associated Brain Metastases

272

Prediction of Breast Cancer Risk After a Benign Breast Biopsy: A Practical Model?

273

Prophylactic Anticoagulation in High-Risk Metastatic Germ Cell Tumor Patients: Who Should We Treat?

274

The Risk of Second Cancers for Patients with Endometrial and Rectal Cancer Receiving Radiation Therapy

275

Better Outcome of Chemo-Irradiation of Head and Neck Cancer in High-Patient-Volume Institutions

276

Is There a Future for Cyclooxygenase-2 Inhibition in Non-Small Cell Lung Cancer?

277

The Treatment of Insomnia in Cancer Patients

278

The Biopsy Study: How the Use of Multiple Colposcopic-Directed Biopsies Improves Detection of Cervical Precancers

279

Intensified Frontline Chemoimmunotherapy with R-ACVBP May Improve Outcomes for Younger Patients with Non-Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma

280

A Positive Study of DTC-Guided Secondary Adjuvant Treatment in Early Breast Cancer: Ready for Prime Time?

281

A Second Course of Radiation Therapy for Painful Osseous Metastases Improves Patient Function and Quality of Life

282

Adjuvant Trastuzumab Passes the Test of Time

283

Prognostic Value of BRAF V600 E Mutation in Papillary Thyroid Cancer

284

Biochemotherapy: As Time Goes By?

285

The First Prospective Trial of Proton Therapy for Children With Rhabdomyosarcoma: What We Learn From Preliminary Results

286

Intermediate Risk Pediatric Hodgkin Lymphoma: Early Response-Adapted Treatment Is Key

287

Keeping Older Cancer Patients out of the Hospital: A Community Affair

288

Optimal Duration of MRD Monitoring During Therapy for Childhood ALL

289

Hepatitis B Reactivation in Patients Receiving Rituximab Can Be Detected Early and Managed with Antivirals

290

CT or No CT: An Important Question in Diffuse Large B-Cell Lymphoma

291

Glembatumumab Vedotin (CDX-011, CR011-vcMMAE): On The Brink Of Targeted Therapy For Triple-Negative Breast Cancer?

292

Post-Transplant Cyclophosphamide for GVHD Prophylaxis: Back to the Future

293

The Price Of A Drug is Not the Whole Cost

294

Cabozantinib in Advanced Prostate Cancer: Is the Therapeutic Window Too Narrow?

295

Fracture Risk after Cystectomy: Don't Ignore It

296

Is Hematopoietic Stem Cell Transplantation of Value in Treating Systemic Mastocytosis?

297

Significant Dose Effect of Radiotherapy to the Pancreas and Risk of Diabetes Mellitus in Long-Term Hodgkin Lymphoma Survivors

298

The End of Rituximab Maintenance for Low Tumor Burden Follicular Lymphoma

299

Use of Mutational Analysis to Help Decide Whether Patients with Myelodsysplastic Syndromes Should Receive Allogeneic Hematopoietic Cell Transplant

300

Why are Fellows' Burnout Rates as High as Those of Practicing Oncologists?

301

Surprisingly Good Results in BCR-ABL1-like Pediatric Acute Lymphoblastic Leukemia: What Do They Mean?

302

Should Corticosteroids Be Used for the Treatment of Pain, Fatigue and Loss of Appetite in Cancer Patients Receiving Opioids?

303

Breast Reconstructions: Inequities in Access Affecting Choice and Quality

304

Recurrent/Metastatic Human Papillomavirus-Associated Oropharynx Cancer: What Happens When This Good Prognostic Cancer Misbehaves?

305

Long Term Cardiac Safety Data from the HERA Adjuvant Trastuzumab Trial

306

Breast Needle Core Biopsy: The Impact Surgeons and Geography Have on Utilization and the Impact on Patient Care

307

Identifying High-Risk Myeloma

308

Attempting to Avoid Chemotherapy in CLL with Lenalidomide and Rituximab

309

Breast Cancer Chemotherapy Effects on Brain Activation During Multitasking and Relation to Cognitive Complaints

310

Delayed Diagnostic Lumbar Puncture to Optimize Central-Nervous-System-Directed Therapy in Childhood Acute Lymphoblastic Leukemia

311

Capecitabine Versus Continuous Infusion 5-FU for Rectal Cancer Neoadjuvant Chemoradiation: Equivalent Effectiveness Raises Real-World Questions About Efficacy, Adherence and Economic Implications

312

Evolving Treatment Paradigms for Primary Mediastinal Diffuse Large B-Cell Lymphoma

313

Response Assessment in Hodgkin Lymphoma: Size Matters!

314

Second Tumors in PTEN Mutation-Positive Patients: Are They Recurrences or New Primaries?

315

Are Partners of Patients HPV-Positive Oropharyngeal Cancer at Increased Risk of Infection and Cancer?

316

Planning to Survive: The Role of Physicians

317

Minimal Residual Disease (MRD) Study to Optimize Definition and Therapy of High-Risk Acute Lymphoblastic Leukemia

318

Risk-Reducing Oophorectomy in Women with BRCA1 and BRCA2 Mutations: An Opportunity to Personalize Recommendations for Cancer Prevention

319

Anti-EGFR Monoclonal Antibodies in the First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The PEAK Experience

320

Accuracy of BRCAPRO in Women with Ovarian Cancer

321

Serious Bevacizumab-Associated Gastrointestinal Toxicity

322

The Efficacy of Bevacizumab Combined with Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer Patients and Its Effects On Patient-Reported Outcomes

323

Nivolumab: Promising Survival Signal Coupled with Limited Toxicity Raises Expectations

324

Decision Shared or Otherwise-: The Ongoing Evolution of Local Therapy for Breast Cancer

325

Is Early Initiation of Adjuvant Chemotherapy for Breast Cancer Better?

326

Single Agent Rituximab Active in Nodular Lymphocyte Predominant Hodgkin Lymphoma

327

Adjuvant Treatment for Gastric Cancer: The Story Continues to Evolve

328

Benefits of Modified Craniospinal Radiation Therapy for Children Treated for Medulloblastoma: Preserving Long-Term Neurocognitive Function

329

Breast MRI As It Is, In Contrast To How We Wish It To Be

330

New Adoptive T Cell Therapy Has EBV-Positive Lymphomas on the Run

331

Adjuvant High-Dose Interferon: New Evidence Regarding Treatment Duration and Survival Impact in Melanoma

332

Some like It Even Hotter: Escalating Radioimmunotherapy in Follicular Lymphoma?

333

Increasing Cytarabine Dose in AML Induction Improves Outcomes in Younger Patients

334

The Value of Preoperative MRI in Predicting Outcome in Patients with Rectal Cancer

335

Refining Stringency of Response in Myeloma

336

When Hodgkin Lymphoma Relapses in The Older Patients

337

How Do We Decide Who Should Be Offered a Sentinel Node Biopsy When Their Melanoma Is Less than 1mm in Thickness?

338

FISH for Smoldering Multiple Myeloma

339

External Beam Accelerated Partial Breast Irradiation: Exploring the Limits of Tolerability

340

Minimal Residual Disease (MRD) in Acute Myeloid Leukemia- Are we Ready for Individualized Risk Assessment Based on MRD?

341

Functional Imaging as a Biomarker for Survival in Locoregionally Advanced Non-Small Cell Lung Cancer Patients

342

EORTC 18961 GMK Vaccine Adjuvant Trial: Unfulfilled Promise for Another Vaccine Trial

343

Lenalidomide Monotherapy for Relapsed Mantle Cell Lymphoma

344

Flying Solo: Chemotherapy Without Radiation for Primary Central Nervous System Lymphoma

345

Second Hematopoietic Transplants for Relapsed AML

346

In End-Of-Life Decision-Making, Does DNR Measure Up?

347

A Clear Answer to the Wrong Question

348

Bisphosphonate-Related Osteonecrosis of Jaw (BOJN) in the Adjuvant Breast Cancer Setting: Risks and Perspective

349

Should Myeloma Residual Disease Become a Standard Assay for Large Cooperative Groups and Myeloma Referral Centers?

350

The Prognosis of Breast Cancer Diagnosed During Pregnancy

351

The SUCCEED Trial: Maintenance Ridaforolimus for Metastatic Soft- Tissue Sarcomas

352

Who Needs What Therapy? The Elusive Search for Predictive Markers

353

Micro RNAs and Other Molecular Markers in AML Therapeutics

354

Neuroanatomic and Neuropsychological Outcomes in Adults after Treatment for Childhood Acute Lymphoblastic Leukemia

355

HERA Indicates that Adjuvant Trastuzumab Confers Equal Benefit for HER2-Positive Invasive Ductal and Invasive Lobular Breast Cancers

356

New Evidence of the Clinical Significance of Cigarette Smoking by Colon Cancer Patients

357

Radiotherapy for Pediatric Hodgkin Lymphoma: Are We Ready To Say Goodbye?

358

Minimal-Intensity Conditioning: A Decade Later

359

Evolution of Concurrent Chemoradiation Treatment Approaches in Head and Neck Cancer

360

Off-Label Cancer Therapy Use: How Much is Too Much?

361

Caring For Patients With Transformed Follicular Lymphoma

362

Outpatient Therapy for Fever and Neutropenia is Safe But Implementation is the Key

363

Outcomes in Cancer Survivors Who Develop Second Malignant Neoplasms

364

Molecular Profiling of Gastric Cancer: Toward Personalized Cancer Medicine

365

Reflections on "Cancer Survivorship": Evolution, Utility, and Acceptability

366

Estimating the Risk for Contralateral Breast Cancer as a Guide for Surgical Treatment

367

Revisiting Combination TACE-RFA Treatment for HCC

368

Novel Insights From a Phase II MEK Inhibitor Trial in BRAF Mutant Melanoma

369

Successful Non-Intensive Bridging of MDS Patients Towards Allografting

370

Using a Video Decision Support Tool for CPR Decision-Making

371

Radioimmunotherapy for the Initial Treatment of Follicular Lymphoma

372

Management of Metastases to the Brain: A Therapeutic Conundrum

373

Understanding the Role of MET Kinase in Cancer Therapy

374

AIDS Related Lymphomas - More Options and More Questions

375

Long Term Follow-up of NSABP B-31: How Well Can We Predict Cardiac Toxicity with Trastuzumab?

376

More Adjuvant Chemotherapy is Not Always Better

377

Hodgkin Lymphoma: Protecting the Victims of Our Success

378

Beyond the Plasma Cell: Proteasome Inhibition in Acute Myelogenous Leukemia

379

Breast Brachytherapy in the United States: Increasing Use Despite Increased Complication Rates

380

Referral Practices to Palliative Care Among Canadian Oncologists

381

Clinical Utility of Screening Tests in Asymptomatic Long-Term Childhood Cancer Survivors

382

Is Lymphatic Mapping Ready for Clinical Use in the Treatment of Squamous Vulvar Cancer?

383

Rituximab Maintenance Therapy After Autologous Stem Cell Transplantation: Final Analysis of the CORAL Trial

384

Informed Consent for Pediatric Phase I Cancer Trials: An End-of-Life Decision

385

Outcome in Systemic Anaplastic Large Cell Lymphoma: Beyond ALK

386

Should Gemtuzumab Ozogamicin Be Re-added to the Therapeutic Armamentarium for Acute Myeloid Leukemia?

387

Immunohistochemical Double Hit Score in Diffuse Large B-Cell Lymphoma: The Potential to Screen All Tumors for High-Risk Biology

388

In a Sea of Data the Water is Still Murky: Meta-Analysis of Cognition in Breast Cancer

389

KRAS G13D Mutations in Metastatic Colorectal Cancer: Are They Different From Codon 12?

390

Taxane Induced Peripheral Neuropathy: A Continued Challenge but Not a Biomarker of Treatment Efficacy

391

Is This Nomogram Ready To Roll?

392

Adjuvant Chemotherapy in Older Patients with Stage III Colon Cancer

393

The Combination of Bortezomib, Thalidomide, and Dexamethasone in Relapsed Multiple Myeloma

394

Personalized Therapy for Breast Cancer: Is It Really Happening?

395

Routine Second Pathology Review for Node-Negative Breast Cancer: What is Learned and What is the Effect on Patient Care?

396

Pre-Operative Metformin in Early-Stage Breast Cancer

397

Fulvestrant and Anastrozole in Combination: FACT or Fiction?

398

A New Day Dawning for Hodgkin Lymphoma?

399

The German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow Up of 11 Years: Implications of Long Term Follow Up

400

Carboplatin-Gemcitabine-Bevacizumab: Expanding Treatment Options for Recurrent Platinum Sensitive Epithelial Ovarian Cancer

401

The Use of Adjuvant Therapy in Elderly Patients with Resected Non-Small Cell Lung Cancer (NSCLC)

402

Management and Prevention of Pain Related to Treatment or Disease

403

1 + 1 = 3. Combined Use of Anti-HER2 Agents in the Neoadjuvant Setting

404

Management of Low Stage Ovarian Clear Cell Carcinoma

405

Surviving Childhood Cancer: Defining Risk of Poor Cardiac Outcomes in Early and Middle Adulthood

406

No Advantage to Combining Cetuximab with 5FU, Leucovorin, and Oxaliplatin in Metastatic Colorectal Cancer

407

Sorting Through Early Melanomas to Identify Those at Higher Risk for Metastases

408

Sedation for the Management of Refractory Suffering

409

The Role of the Estrogen Receptor (ER) in Selecting Women, Diagnosed with DCIS for Adjuvant Therapy with Tamoxifen

410

How Cooperative Group Trials Impact Breast Cancer Care in United States

411

What's Different Between One Colorectal Cancer and Another? It's All in the Genes

412

Molecular Tumor Analyses Followed by First Line Oral Tyrosine Kinase Inhibitors in Lung Adenocarcinomas with Driver Abnormalities

413

Placing the P Value into Perspective: Does Paclitaxel Add Value to Gemcitabine and Cisplatin in Advanced Urothelial Cancers?

414

Early Stage Hodgkin Lymphoma -- How Much is Enough?

415

The Rich Get Richer: Another Efficacious Option for Refractory Hairy Cell Leukemia

416

Rethinking Our Use of CSFs in the Adjuvant Treatment of Women Who Have Estrogen Receptor Positive Cancers

417

Recurrence and Survival Results of the GOG Lap2 Trial Confirm Safety of the Laparoscopic Approach to Surgical Staging and Treatment for Uterine Cancer

418

"Anything You Can't Do, I Can't Do Either": Transplantation for High Risk AML

419

Safety and Efficacy of Sequential Adjuvant AI Therapy in ER Positive Breast Cancer

420

The Role of Ovarian Suppression for Fertility Preservation in Women Receiving Adjuvant Breast Cancer Chemotherapy

421

Using BCR-ABL Transcript Levels After 3 Months of Therapy on Imatinib is the Best Way to Predict Long-Term Outcome for Patients with CML Treated with Imatinib

422

The Importance of Tumor Biopsies for Analysis of Mechanisms of Response and Resistance in Prostate Cancer

423

Targeting the Angiopoietin-Tie2 Axis: A Promising Alternative Antiangiogenic Strategy for Epithelial Ovarian Cancer

424

Interim PET Scans in Diffuse Large B-Cell Lymphoma - More Than Another Biomarker?

425

To Biopsy or Not to Biopsy? That is the Question

426

Disparities in Systemic Therapy for Breast Cancer

427

Adjusting for Treatment Cross-Over to Enable Analysis of Longer Term Outcomes in the MA.17 Trial

428

Obesity and Colorectal Cancer: What's the Big Deal?

429

Combinations or Single Agents, Crossover or No Crossover: Considering Chemotherapy Strategies in the Multi-Chaptered Story of Metastatic Breast Cancer

430

Medical Oncologist Attitudes and Practice in Cancer Pain Management: A National Survey

431

Is a "Wait and See" Nonoperative Approach Justified after Chemoradiation for Rectal Cancer

432

Predictive Testing for BRCA1/2 Mutations: The Value of the "True"Negative

433

Trastuzumab in the Adjuvant Setting - Sequential versus Concurrent: Will We Ever Know the Full Answer?

434

Solving the Mystery of Recurrence in "Surgical Cures" for Early Non-Small Cell Lung Cancer

435

Comorbidity Data in Cooperative Trials: Feasible and Non Ignorable

436

Gender Equity and HPV-Associated Cancers in the United States

437

Biomarker Selection for Maintenance Therapy in Advanced NSCLC

438

Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia

439

R-CHOP Chemotherapy as Upfront Treatment for Advanced Stage Follicular Non-Hodgkin Lymphoma

440

Venlafaxine and Clonidine for Treatment of Hot Flashes in Women with Breast Cancer

441

Response to Neoadjuvant Systemic Therapy for Breast Cancer in BRCA Mutation Carriers and Non-Carriers: A Single Institution Experience

442

Individualizing the Risk of Cardiovascular Mortality Following Androgen Deprivation Therapy for Prostate Cancer

443

High Risk Stage II Colon Cancer: What is the Role of Adjuvant Chemotherapy?

444

Is Genotype Guided Tamoxifen Dosing Ready for Prime Time?

445

Menopausal Hormone Therapy, Mammographic Density and Breast Cancer

446

The Growing Value of Risk Calculators for Men Considering Prostate Cancer Screening

447

Interpretation of the Biomarker Analysis and Final Overall Survival Results from IPASS

448

Curing Leukemia with a Single Drug

449

Vaccination with an Autologous Idiotype Based Vaccine Following a Chemotherapy Induced Remission Holds Promise in the Treatment of Patients with Follicular Lymphoma

450

Pathologic Complete Response and Toxicity Results from the STAR-01 Trial Evaluating the Addition of Oxaliplatin to Neodjuvant Chemoradiation for Locally Advanced Rectal Cancer

451

MEK Inhibitors

452

Angiogenic Therapy in Breast Cancer: Axitinib with Chemotherapy Joins the Crowd

453

Advanced Radiation Therapy Technology Improves Survival in Lung Cancer

454

The Dark Side of del(5q) MDS

455

Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer: Is it Ready for Prime Time?

456

Are Lung Cancers with BRAF Mutations Another Molecularly Defined Subgroup of Patients?

457

Targeting the VEGF Receptor in Colon Cancer: Lessons Learned from Negative Trials

458

The Performance of Breast MRI Screening Among Women with BRCA1/2 Mutations

459

Circulating Tumor Cells in Resectable Colorectal Cancer

460

Results From a Phase I Trial of TG101348, a Selective JAK2 Inhibitor with Significant Activity in Symptomatic Myelofibrosis Patients

461

RIBBON-1 Revisited

462

Noninferiority of Denosumab As Compared With Zolendronic Acid With Respect to the Ability to Delay Skeletal Events in Patients With Solid Tumors and Multiple Myeloma