The NatureCity Podcast

PODCAST · health

The NatureCity Podcast

The Nature City Podcast dives into the world of supplements and nutrition to help you make the best decision for your health and lifestyle needs. Hosted by CEO and Founder Carl Pradelli, The Nature City Podcast is your go-to podcast for all things supplements, nutrition, and much more.To learn more about Nature City and our work, visit https://www.naturecity.com/You can also follow us on Youtube to watch the latest episodes, of the Nature City Podcast

  1. 135

    Why Taking Collagen Alone Isn't Enough (And the 5 Nutrients Most People Miss)

    Most collagen advice stops at the supplement aisle. Subscribe for what comes next: https://www.youtube.com/@naturecitysupplements In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, walks through what the body actually does with collagen peptides — and the five nutrients that turn those fragments into actual collagen for healthy skin, hair, joints, and connective tissue.Collagen is the most abundant structural protein in the human body, and it holds together everything from skin and cartilage to tendons, ligaments, bones, and blood vessels. Production declines with age, which is why collagen has become one of the largest categories in supplements for skin, hair, joints, and healthy aging.Reaching for a collagen supplement is a reasonable response. The confusion starts with what happens next. Collagen peptides are not finished collagen. They are fragments — broken-down pieces of collagen protein that the body still has to digest, absorb, and use as raw material before any of it ends up in your skin or joints.That distinction reframes the entire question. Rather than asking whether to take collagen, Carl walks through what the body actually needs to build and maintain it. Vitamin C is non-negotiable for collagen synthesis — without enough of it, the body cannot properly form collagen, which is one reason vitamin C has been linked to skin health and wound healing for as long as nutrition science has existed.Silica, a mineral containing the element silicon, supports the architecture of skin, hair, nails, and connective tissue. Glycine, one of the primary amino acids inside collagen itself, is a major part of its structure. OptiMSM provides sulfur, a key structural element across the connective-tissue matrix, which is why MSM has earned its place in both beauty and joint-health conversations. None of these are alternatives to collagen peptides. They are the building blocks and structural supports that determine whether the peptides you take get used. Building collagen is only half the work. The collagen already in your body is under constant pressure from oxidative stress, UV exposure, an unhealthy inflammatory response, and normal aging — and protecting it matters as much as building more. This is where astaxanthin earns its reputation as one of nature's most powerful antioxidants.The skin cells that produce collagen, called fibroblasts, can have their output reduced or shut down entirely when free radicals attack them. Astaxanthin's antioxidant properties help defend fibroblasts so they can keep producing collagen, while protecting the tissues collagen already holds together. For anyone focused on skin health, joint health, or visible aging, that protective layer is the piece a collagen-only routine misses.Collagen support is a system, not a single supplement. Collagen peptides supply raw material, but vitamin C, silica, glycine, OptiMSM, and astaxanthin do the building, structural, and protective work the body relies on to turn that raw material into healthy tissue.NatureCity's TrueNuGrow+ formula combines collagen with nutrients that support hair, skin, and connective tissue from several angles, and TrueJointFLX uses the NEM eggshell membrane complex — which contains collagen alongside supporting nutrients — for joints, muscles, and surrounding connective tissue.ABOUT NATURECITYNatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. Over 500,000 customers served.LEARN MORETrueNuGrow+: https://www.naturecity.com/products/truenugrow?_pos=1&_psq=truenugro&_ss=e&_v=1.0TrueJointFLX: https://www.naturecity.com/products/true-joint-flx?_pos=1&_psq=truejoint&_ss=e&_v=1.0Visit naturecity.com or contact us with any questions: https://www.naturecity.com/ or [email protected] #NatureCity #Collagen #HealthyAging #Astaxanthin #Supplements

  2. 134

    Why Most Curcumin Supplements Underperform (And the Absorption Fix)

    Turmeric and curcumin are not the same thing — and most curcumin supplements are poorly absorbed. Subscribe for more supplement truth from Carl Pradelli.In this episode, Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down the real reason so many curcumin supplements underperform: absorption. The milligram number on the bottle is only half the story. What matters is how much your body can actually use.Turmeric is the yellow-orange spice used in cooking. Curcumin is the key compound inside turmeric that research has linked to a healthy inflammation response, joint comfort, cognitive support, immune function, mood balance, and cardiovascular health. Raw turmeric powder only contains about 2 to 5 percent curcumin, which means reaching a meaningful supplemental dose from turmeric alone would require roughly eight grams per day — not practical for almost anyone.Once curcumin is isolated, it becomes poorly absorbed during digestion. That is where many supplement companies mislead consumers. A bottle can list 500 milligrams or even 1,000 milligrams of curcumin and still deliver very little to the bloodstream. A common fix is combining curcumin with piperine, a black pepper extract, but piperine is a foreign absorption enhancer and can raise questions about interactions with other substances.Carl explains why NatureCity uses BCM-95 in True Curcumin. BCM-95 reunites curcumin with turmeric's own essential oils — no foreign enhancers, all from the turmeric plant itself. Just 400 milligrams of BCM-95 has been shown to be equivalent to about 2,500 milligrams of regular curcumin in terms of absorption and sustained presence in the bloodstream. BCM-95 is backed by over 90 published independent research papers and an 18-year track record in 60 countries.He also covers True Joint FLX, which uses TamaFlex — a research combination of turmeric and tamarind seed backed by three separate human clinical studies for joint health. The takeaway for every supplement buyer: look past the milligram number. Ask two questions instead. Is it absorbed? And does the specific extract have human clinical research behind it?ABOUT NATURECITYNatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served across 20+ years, NatureCity is committed to quality, honesty, and results.LINKSTrue Curcumin: https://www.naturecity.com/products/true-curcumin?srsltid=AfmBOoqm6l-h5VGsz_Ul9npMMuA1LC9--5rXxhP-JSTmflrO97ZLAF3GTrueJoint FLX: https://www.naturecity.com/products/true-joint-flx?srsltid=AfmBOopmkl90VG77ZY8zLnEfuXUhgB_I5E3RHxJ0Fesg46kjQVIBXuHvNatureCity website: https://www.naturecity.comSubscribe: https://www.youtube.com/@naturecitysupplements#NatureCity #Curcumin #Turmeric #JointHealth #Supplements

  3. 133

    Calming Energy: How to Stay Focused Without Caffeine Crashes

    Struggling to stay focused without reaching for another cup of coffee? Carl Pradelli, CEO and Co-Founder of NatureCity, explains why stimulation is not the same as focus and how calming energy can transform your productivity. WHAT YOU'LL LEARN✓ Why caffeine creates short energy spikes followed by crashes that hurt focus✓ What "calming energy" means and why it outperforms stimulation for sustained productivity✓ How enXtra Thai ginger supports alertness for up to five hours without caffeine or sleep disruption✓ How PharmaGABA promotes calm focus without drowsiness✓ How LandKind salidroside helps your body handle stress and reduce mental fatigue This episode of the NatureCity Podcast arrives during Stress Awareness Month, and Carl Pradelli connects the dots between everyday stressors and the focus and energy problems most people try to solve with more caffeine. The issue, Carl explains, is that caffeine delivers short-lived stimulation, not focus. When your stress response system is constantly activated, flooding your body with cortisol and adrenaline, true mental clarity becomes difficult regardless of how much caffeine you consume. Carl introduces a concept NatureCity calls calming energy: steady, controlled mental energy that supports focus without the jitters, crashes or feelings of anxiety that may come with repeated stimulant use. A calming energy approach is about maintaining consistent focus, steady energy, and a calm mental state throughout the day. He breaks down three key ingredients that can work together to help create this balanced state. enXtra, derived from Thai ginger, has been shown in placebo-controlled studies to support alertness, improved reaction time and fewer errors for up to five hours. PharmaGABA, a natural form of the neurotransmitter GABA, promotes relaxation and a calm mental state without drowsiness. LandKind salidroside (the key adaptogen compound from the Rhodiola plant) supports cognitive performance under stress and can help protect against mental fatigue. These three ingredients are the foundation of NatureCity's TrueMind formula, which also includes active forms of key B vitamins for cellular energy production. Carl shares his personal routine of taking TrueMind between 10 and 11 a.m. for sustained productivity through the rest of the business day.SUBSCRIBE to the NatureCity Podcast for weekly episodes on natural health, science-backed supplements and wellness strategies that actually work.ABOUT NATURECITYNatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty and results.https://www.naturecity.com/#NatureCity #CalmingEnergy #StressRelief #NaturalFocus #TrueMind

  4. 132

    Magnesium Bisglycinate Chelate vs. Glycinate: What You’re Not Being Told

    Is your magnesium supplement actually what it claims to be? Carl Pradelli, CEO and Co-Founder of NatureCity, breaks down the critical difference between magnesium glycinate and magnesium bisglycinate chelate so you stop wasting money on supplements that may look good on the label but don’t deliver. Subscribe for weekly supplement truths. WHAT YOU’LL LEARN✓ Why magnesium glycinate and magnesium bisglycinate chelate are NOT always the same thing✓ How some brands blend magnesium oxide with glycine and still call it magnesium glycinate✓ The 10% elemental magnesium rule that exposes low-quality supplements instantly✓ Why Albion is considered the gold standard for chelated mineral sourcing✓ How NatureCity-’s TrueMagnesium delivers 200mg of pure bisglycinate chelate in a drink powder Magnesium is involved in over 300 processes in your body, from sleep and muscle function to energy, mood, and heart health. Most people are not getting enough magnesium from diet alone, which makes supplementation important. But here is the problem: not all magnesium supplements are created equal, and the labels could be misleading. In this episode, Carl Pradelli explains the details behind magnesium bisglycinate chelate, a fully reacted form of magnesium bound to two glycine molecules. This form has been shown to be absorbed up to 3x to 4x times better than other magnesium options with significantly fewer digestive issues. This makes it one of the most desirable forms of magnesium for supplements. Usually, magnesium bisglycinate chelate is labeled as such, but technically it could be also labeled as “magnesium glycinate.” However, here is the important part you need to know: not all magnesium glycinate is magnesium bisglycinate chelate. Carl exposes how some supplement companies use partially reacted magnesium or blend magnesium oxide with glycine, and label it as magnesium glycinate - but this is not a true and pure magnesium bisglycinate chelate and will not perform like it in the body. Carl walks through how to read a supplement label to spot the difference, including the 10% elemental magnesium benchmark. You’ll also see why high milligram-per-capsule magnesium claims are a red flag, and why Albion’s patented chelation process matters. He also explains why NatureCity chose a raspberry-flavored drink powder format for TrueMagnesium to deliver a full 200mg dose of pure Albion magnesium bisglycinate chelate without requiring a handful of capsules. NatureCity was founded over 20 years ago by Carl Pradelli and his wife Beth with a mission to deliver transparent, science-backed natural health supplements. Since then, NatureCity has served over 500,000 customers and remains committed to quality, honesty, and results. TIMESTAMPS0:00 — Why your magnesium supplement might not be working0:38 — Why magnesium matters for sleep, energy, and overall health1:20 — The confusion: glycinate vs. bisglycinate2:05 — The key difference that actually matters2:50 — What makes this form easier for your body to absorb4:35 — The problem with most magnesium supplements5:45 — Why some “glycinate” isn’t really glycinate6:25 — The truth about “buffered” magnesium7:10 — How to read a magnesium label the right way8:05 — How to spot a low-quality supplement fast9:05 — Recap: how to choose the right magnesium Learn more about TrueMagnesium and NatureCity’s full supplement line at naturecity.comABOUT NATURECITYNatureCity was founded by Carl Pradelli with a mission to deliver transparent, science-backed natural health supplements. With over 500,000 customers served, NatureCity is committed to quality, honesty, and results.#NatureCity #MagnesiumSupplement #MagnesiumBisglycinate #NaturalHealth

  5. 131

    Biotin and Silica for Hair: New Study Shows Real Results

    Hair thinning and excess shedding are common concerns — but can targeted nutrition help?In this episode of the NatureCity Podcast, Carl Pradelli breaks down a new placebo-controlled study evaluating plant-based biotin (RGen-Bio®) and silica (RGgen-Si™), and their impact on hair loss, hair growth, thickness, and overall appearance. Plus, you’ll see how these nutrients helped skin and nails too.You’ll learn how these nutrients support the hair growth cycle, why mitochondrial activity matters at the follicle level, and what the research actually showed after 90 days.Watch now to see what the science says. → Learn more about TrueNuGrow+ at https://www.naturecity.com/products/truenugrow WHAT YOU'LL LEARN IN THIS EPISODE ✓ How a 90-day placebo-controlled trial measured real improvements in hair loss, thickness, density, and shedding ✓ The three phases of hair growth and what causes follicles to shift into the shedding phase ✓ The role of biotin in keratin production and follicle metabolism ✓ How silica supports collagen formation to anchor hair follicles and strengthen the hair shaft ✓ Bonus benefits: skin elasticity, hydration, wrinkle reduction, and smoother nails from the same nutrients EPISODE BREAKDOWNA newly published randomized, double-blind, placebo-controlled study tested plant-based biotin (from RGen-Bio, extracted from the sesbania plant) and silica (from RGen-Si, extracted from bamboo shoots) on 97 men and women aged 20 to 60. All participants reported hair appearance concerns at baseline. Over 90 days, participants taking 2.5 mg of biotin daily — or the biotin combined with 40mg of silica — experienced significant reductions in daily hair fall (normal hair loss), meaningful increases in hair thickness and density measured by advanced scalp imaging, and faster hair growth rates compared to placebo. Carl explains how these results connect to the three-phase hair growth cycle: anagen (active growth), catagen (transition), and telogen (resting and shedding). When nutritional deficiencies, stress, or aging push more follicles into the telogen phase, shedding accelerates. Biotin supports keratin production and cellular energy metabolism in follicles, while silica supports the collagen and connective tissue that anchor hair in the scalp. Researchers also observed improvements in skin elasticity, hydration, crow’s feet wrinkle appearance, and fingernail smoothness — because hair, skin, and nails share the same structural proteins and may all benefit from biotin and silica support. NatureCity’s TrueNuGrow+ formula uses these exact plant-based biotin and silica sources at the same doses proven effective in this study, plus additional research-backed nutrients for comprehensive hair and skin support.SUBSCRIBE to the NatureCity Podcast so you never miss an episode on evidence-based nutrition and supplement science.🌿 RESOURCESTrueNuGrow+ Hair & Skin Formula: [INSERT LINK]NatureCity Website: https://www.naturecity.comABOUT NATURECITYFounded over 20 years ago by Carl and Beth Pradelli, NatureCity has served more than 500,000 Americans with premium, research-backed supplements. Every product is built on four ironclad commitments to quality, transparency, potency, and purity.Follow NatureCity:Instagram: https://www.instagram.com/NatureCitySupplements/ Facebook: https://www.facebook.com/naturecitysupplements#NatureCity #BiotinForHair #HairGrowthSupplements #PlantBasedBiotin #HealthyHairScience

  6. 130

    Beyond Heart Health: Ubiquinol Supports Brain, Muscle & Bone Health Too

    Your body runs on cellular energy, and your cells constantly need to produce new energy.In the last episode, we explored how ubiquinol, the active form of CoQ10, supports heart health by fueling the massive energy demands of the heart. But the heart is not the only organ that relies heavily on cellular energy.In this episode of the NatureCity Podcast, CEO and co-founder Carl Pradelli expands the conversation beyond cardiovascular health and explains how ubiquinol can also support healthy function of the brain, skeletal muscle, and bone tissues.Carl explains how ubiquinol helps mitochondria produce ATP, the cellular energy your body runs on, while also helping protect cells from oxidative stress. Both processes become increasingly important as we age.Subscribe to the NatureCity Podcast for weekly science-backed supplement insights.WHAT YOU'LL LEARN✅ Why the brain uses about 20 percent of the body’s total energy✅ How mitochondrial decline contributes to fatigue, muscle loss, and cognitive aging✅ The connection between cellular energy and healthy brain function✅ How CoQ10 may support muscle performance and exercise recovery✅ Why researchers are exploring ubiquinol’s role in bone metabolism and bone health✅ How supporting mitochondrial health may promote whole body resilience as we ageEPISODE SUMMARYMost people associate CoQ10 and ubiquinol with heart health, and for good reason. In our previous episode, we discussed how the heart beats about 100,000 times per day and depends heavily on mitochondrial energy production to keep working nonstop. But the heart is only one of several tissues in the body that rely on efficient cellular energy production.In this episode, Carl expands the conversation to three additional areas where mitochondrial energy plays a critical role: the brain, skeletal muscle, and bone.Although the brain represents only about 2 percent of body weight, it consumes roughly 20 percent of the body’s energy supply. Every thought, memory, and nerve signal depends on ATP produced inside brain cells. Research suggests that maintaining mitochondrial efficiency may be one of the most important strategies for supporting cognitive health as we age.Skeletal muscle is another tissue that relies heavily on energy production. Muscle cells require ATP for every contraction, whether you are walking, exercising, or simply standing. Studies suggest CoQ10 supplementation may help support muscle energy production, reduce exercise related fatigue, and promote recovery.Emerging research also suggests ubiquinol may support healthy bone metabolism. Bone is constantly being remodeled through the balance of bone-forming osteoblasts and bone-breaking osteoclasts. Oxidative stress and mitochondrial dysfunction may influence this balance, making cellular energy an important factor in maintaining healthy bone density.Across all these systems, a clear pattern emerges. The brain, muscles, bones, and heart all depend on efficient cellular energy production and protection from oxidative stress. Ubiquinol supports both of these processes by helping mitochondria produce energy while also acting as a powerful antioxidant.TIMESTAMPS00:00 Introduction00:47 Recap of last episode on ubiquinol and heart health01:27 Why cellular energy matters beyond the heart01:45 The brain’s massive energy demand02:30 How ubiquinol may support brain health03:21 Skeletal muscle and mitochondrial energy04:00 CoQ10 research on exercise and recovery04:26 Why muscle health supports independence as we age04:44 Ubiquinol and emerging research on bone health05:06 Osteoblasts vs osteoclasts and how bone remodeling works06:05 The bigger picture of mitochondria and healthy aging07:06 How TrueCoQ10 supports cellular energy production07:22 NatureCity’s advanced ubiquinol delivery system07:37 Final thoughts and episode wrap-upSUBSCRIBE to the Nature City Podcast for science-backed supplement education from a company that's served over 500,000 Americans in 20+ years.LINKS AND RESOURCESLearn more about True CoQ10:https://www.naturecity.com/products/true-coq10-100mg?_pos=2&_sid=6aff9fd22&_ss=rBrowse all Nature City supplements:https://www.naturecity.com/Watch more Nature City Podcast episodes:https://www.youtube.com/playlist?list=PLRwO7b_fPoq6knehENg5yRD3O5IuoMBmkABOUT THE HOSTCarl Pradelli is the CEO and co-founder of Nature City, a supplement company he started over 20 years ago with his wife Beth. Nature City has served over 500,000 Americans with science-backed, quality-first nutritional supplements.#NatureCityPodcast #Ubiquinol #HealthyAging #Mitochondria #CoQ10

  7. 129

    Your Heart Stores Only 10 Seconds of Energy — Why Ubiquinol Matters

    Your heart beats 100,000 times a day and pumps up to 10 tons of blood — but most people never think about the energy it takes to keep it going. In this American Heart Month episode, NatureCity CEO and co-founder Carl Pradelli breaks down the critical connection between heart health and cellular energy — and explains why ubiquinol, the active form of CoQ10, may be the most overlooked supplement for long-term cardiovascular support. Subscribe to the NatureCity Podcast for weekly science-backed supplement insights. WHAT YOU'LL LEARN ✅ Why your heart needs more energy than any other organ — and what happens when it doesn't get enough ✅ The 4 ways ubiquinol supports heart and cardiovascular health ✅ Why CoQ10 levels drop by 40% between ages 20 and 40 — and keep declining ✅ The difference between ubiquinone and ubiquinol (and why the form you take matters) ✅ How the formulation used in NatureCity's TrueCoQ10 supplement showed 4.3x greater absorption in a double-blind study EPISODE SUMMARY Most conversations about heart health focus on cholesterol, blood pressure, and exercise – all very important . But your heart is also the most energy-demanding organ in your body. A single heart muscle cell contains thousands of mitochondria working around the clock to produce ATP — and your heart stores only about 10 seconds' worth at any given moment. That constant demand makes the heart uniquely dependent on efficient energy production. Ubiquinol, the active antioxidant form of CoQ10, plays a direct role in the electron transport chain that generates ATP. It also protects mitochondrial membranes from the free radicals that energy production creates as a byproduct. Unfortunately, natural CoQ10 levels peak around age 20 and decline steadily from there — dropping approximately 40% in heart cells by age 40. Carl walks through four specific ways ubiquinol supports heart health: fueling the heart's ATP production and supporting healthy ejection fraction, protecting mitochondria from oxidative stress, shielding LDL cholesterol from oxidation (which research suggests ubiquinol may do even more effectively than vitamin E), and supporting nitric oxide production for healthy blood flow and vascular flexibility. The episode also covers why the form and formulation of CoQ10 matters. Carl explains the difference between ubiquinone and ubiquinol, why conversion efficiency declines with age, and how NatureCity's TrueCoQ10 uses Kaneka Ubiquinol with an advanced delivery system that demonstrated 4.3 times greater blood plasma levels in a published double-blind study. Scroll down to the timestamps to jump straight to any of the four heart health benefits. TIMESTAMPS 00:00 Introduction and American Heart Month00:31 The heart's extraordinary energy demands01:23 Mitochondria, ATP, and why ubiquinol matters02:36 CoQ10 levels decline with age03:33 CoQ10 basics: ubiquinone vs. ubiquinol04:41 Benefit 1: Fueling heart energy and ejection fraction06:04 Benefit 2: Protecting mitochondria from oxidative stress07:34 Benefit 3: Shielding LDL from oxidation09:08 Benefit 4: Nitric oxide and healthy blood flow11:04 Why supplementing after age 20 makes sense11:34 Why the form of CoQ10 matters12:09 Kaneka Ubiquinol and quality sourcing12:29 TrueCoQ10's advanced delivery system13:46 The 4.3x absorption study14:46 Dosage recommendations15:09 Summary: ubiquinol at the intersection of energy, oxidative balance, and blood flow SUBSCRIBE to the Nature City Podcast for science-backed supplement education from a company that's served over 500,000 Americans in 20+ years. LINKS AND RESOURCES Learn more about True CoQ10:https://www.naturecity.com/products/true-coq10-100mg?_pos=2&_sid=a66fd410e&_ss=r Browse all Nature City supplements:https://www.naturecity.com/ Watch more Nature City Podcast episodes:https://www.youtube.com/playlist?list=PLRwO7b_fPoq6knehENg5yRD3O5IuoMBmk ABOUT THE HOST Carl Pradelli is the CEO and co-founder of Nature City, a supplement company he started over 20 years ago with his wife Beth. Nature City has served over 500,000 Americans with science-backed, quality-first nutritional supplements. #NatureCityPodcast #Ubiquinol #HeartHealth

  8. 128

    Astaxanthin Update: Vision, Skin, Muscle Recovery & Emerging Brain Health Research

    In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli welcomes back Dr. Karen Hecht, Vice President of Science at AstaReal, along with Dr. Susan Hamrahi, who leads scientific communications.Astaxanthin has long been recognized as one of nature’s most powerful antioxidants — but since Carl and Dr. Hecht’s original deep dive in Episode 9, a wave of new human research has expanded our understanding of how this unique carotenoid supports vision, skin health, muscle endurance and recovery, immune resilience, and even emerging areas of cognitive performance.In this updated conversation, the group breaks down why astaxanthin is structurally different from other antioxidants, how it uniquely protects cells without becoming pro-oxidant, and why its ability to support mitochondrial function makes it relevant for both everyday energy and athletic performance.They also explore why AstaReal® natural astaxanthin, derived from Haematococcus pluvialis algae, has become the gold standard for research-backed supplementation — with over 85 human scientific studies supporting its safety, bioavailability, and effectiveness.If you’re looking for a science-driven update on one of the most versatile nutrients in healthy aging — and want practical guidance on dosing, benefits, and who may benefit most — this episode delivers a comprehensive, evidence-based overview.WHAT YOU'LL LEARNWhat astaxanthin is and why it’s different from other carotenoidsWhy natural astaxanthin from algae matters vs synthetic sourcesHow astaxanthin protects cells without becoming pro-oxidantWhy astaxanthin is considered a mitochondrial nutrientHow it helps with eye fatigue, visual accommodation, and screen-related eye strainWhy astaxanthin complements lutein and zeaxanthin for vision healthHow astaxanthin supports skin hydration, elasticity, and collagen protectionWhy a scientific review ranked astaxanthin among top skin nutrientsNew findings on muscle endurance, recovery, and delayed-onset sorenessHow astaxanthin may support immune resilience during physical stressEmerging research on cognitive performance, reaction time, and moodHow much astaxanthin to take — and how to personalize dosingREFERENCESThe Lopresti Study: https://pubmed.ncbi.nlm.nih.gov/38892705/The ISSN Position Stand on Antioxidants: https://pubmed.ncbi.nlm.nih.gov/41701327/ SUBSCRIBE & CONNECTDon’t miss future episodes packed with supplement science and practical healthy aging insights.✅ Subscribe to the NatureCity YouTube channel🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform💬 Comment below with your biggest takeaway from this episodeExplore NatureCity supplements at 👉 https://www.naturecity.comFOLLOW USInstagram: @NatureCitySupplementsFacebook: NatureCity Supplements#NatureCityPodcast #Astaxanthin #AstaReal #VisionHealth #SkinHealth#MuscleRecovery #MitochondrialHealth #HealthyAging #SupplementScience

  9. 127

    Omega-3s, Brain Health, and Why Blood Levels Matter

    In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli breaks down a newly published study that takes a deeper — and more impactful — look at omega-3s and brain health.Rather than relying on food questionnaires or supplement surveys, this new research measured omega-3 blood levels, offering a clearer picture of how EPA and DHA status relates to the earliest biological stages of age-related cognitive decline. The findings reinforce an idea Carl has emphasized before: when it comes to omega-3s, long-term blood levels matter far more than short-term intake.Carl revisits key insights from Episode 115 on omega-3s and brain health, then explains what makes this study different — including its focus on the Omega-3 Index as a predictor of cognitive aging risk. The research showed that individuals with an Omega-3 Index above 8% had significantly better brain aging outcomes, while most people in Western populations fall far below that range.The episode also explores why simply “taking fish oil” doesn’t guarantee results. Carl explains the importance of consistent intake, proper dosing, balanced EPA and DHA ratios, and — critically — absorption and bioavailability. He breaks down why some people see meaningful benefits from omega-3s while others don’t, and how advanced delivery systems can dramatically impact results.If you’re interested in protecting brain health decades before symptoms appear — and want practical, measurable strategies instead of guesswork — this episode offers clear guidance grounded in human research.WHAT YOU’LL LEARNWhy this new omega-3 study focused on blood levels, not dietary intakeHow omega-3 status relates to early biological stages of cognitive declineWhat “early onset” cognitive changes mattersWhy the Omega-3 Index is the most reliable marker of omega-3 adequacyWhat an Omega-3 Index above 8% means for long-term brain healthWhy most people never reach protective omega-3 blood levelsThe distinct roles of DHA (structure) and EPA (healthy inflammation response & blood flow) in the brainGenetics don’t determine destiny – lifestyle and nutrition matter alsoHow absorption and delivery systems impact omega-3 effectivenessHow omega-3 testing turns supplementation into a measurable strategySUBSCRIBE & CONNECTDon’t miss future episodes packed with supplement science and practical healthy aging insights.✅ Subscribe to the NatureCity YouTube channel🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform💬 Comment below with your biggest takeaway from this episodeExplore NatureCity supplements at 👉 https://www.naturecity.comFOLLOW USInstagram: @NatureCitySupplementsFacebook: NatureCity Supplements#NatureCityPodcast #Omega3 #BrainHealth #CognitiveAging #HealthyAging#Omega3Index #EPA #DHA #LongevityScience #SupplementScience #HealthSpan

  10. 126

    New Science: Resveratrol Can Help Skin Appearance

    In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli breaks down a newly published human study on resveratrol — and why its findings go beyond skin-deep benefits.Resveratrol has long been discussed for its role in healthy aging, heart health, and longevity. But this new research shifts the spotlight to something many people notice first as they age: visible changes in skin firmness, elasticity, and wrinkles. What makes this study especially noteworthy is that it didn’t use just any resveratrol — it used Veri-te® resveratrol, the fermented form found in NatureCity’s TrueResveratrol.Carl walks through exactly what the study showed, who participated, the surprisingly low dose that was used, and why this specific form of resveratrol appears to work differently than many high-dose products on the market. He also explains why improvements in skin health often reflect broader biological support — including antioxidant protection, a healthy inflammation response, mitochondrial function, and cellular repair.Beyond skin aging, the episode explores how resveratrol — particularly the low dose Veri-te® — has also been studied for bone health, cardiovascular support, metabolic function, and brain health, reinforcing its role as a foundational, multi-system aging nutrient rather than a cosmetic-only supplement.If you’re curious about resveratrol but want evidence-based guidance — not hype or mega-dose guesswork — this episode offers clarity, context, and practical takeaways grounded in human research.WHAT YOU’LL LEARNWhy this new resveratrol study focused on visible skin agingWho was studied and why the results are especially relevant for adults over 40The specific skin aging markers that improved in the studyWhy the study used just 150 mg per day — and why that mattersHow skin health reflects deeper cellular aging processesWhy not all resveratrol supplements are created equalHow fermented resveratrol differs from conventional sourcesThe connection between resveratrol, bone health, and agingHow resveratrol supports cardiovascular, metabolic, and brain healthWhy ingredient form and purity matter more as we ageSUBSCRIBE & CONNECTDon’t miss future episodes packed with supplement science and practical healthy aging insights.✅ Subscribe to the NatureCity YouTube channel🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform💬 Comment below with your biggest takeaway from this episodeExplore NatureCity supplements at 👉 https://www.naturecity.comFOLLOW USInstagram: @NatureCitySupplementsFacebook: NatureCity Supplements#NatureCityPodcast #Resveratrol #HealthyAging #SkinHealth #BoneHealth #LongevityScience #AntiAgingResearch #SupplementScience #HealthSpan #VeriteResveratrol

  11. 125

    Do You Really Need Expensive Longevity Supplements?

    In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a step back from the hype surrounding cutting-edge longevity supplements to ask a more practical — and important — question: Do you really need expensive, trendy longevity products to support healthy aging?With longevity now dominating wellness headlines, many supplements promise to slow aging, lengthen telomeres, boost NAD+, or activate autophagy — often at a steep monthly cost and with limited long-term human research. Carl explains why longevity isn’t driven by a single “magic molecule,” but by a network of systems including a healthy inflammation response, oxidative stress protection, cardiovascular health, immune system regulation, brain function, and cellular integrity.In this episode, Carl breaks down how well-established nutrients — backed by decades of human research — already support many of the same biological pathways targeted by newer longevity compounds. He highlights three foundational supplements that almost everyone should prioritize first for both health span and longevity:Vitamin D (especially when paired with Vitamin K2)Omega-3 fatty acids from high-quality fish oilVitamin E tocotrienolsCarl explains how these nutrients support the same health systems targeted by newer longevity compounds, and even mitochondrial function and  telomere integrity too — all without the uncertainty and cost of newer longevity “stacks.”You’ll also learn why optimizing the fundamentals can deliver powerful aging benefits today, not just theoretical lifespan gains decades from now.If you’re curious about longevity but want science-backed, realistic guidance before spending hundreds of dollars a month on supplements, this episode is for you.WHAT YOU’LL LEARNWhy longevity isn’t controlled by one single nutrient or pathwayThe hidden downside of expensive, cutting-edge longevity supplementsNetwork of systems that influence agingWhy Vitamin D is one of the most underestimated longevity nutrientsThe role Vitamin K2 plays alongside Vitamin DWhy omega-3s are often called the “original longevity supplement”How omega-3s support heart health, brain health, and telomeresWhat tocotrienols are — and why most vitamin E supplements miss themHow tocotrienols support cellular, mitochondrial, and brain healthWhat telomeres really are and how you can protect themWhy consistency beats novelty when it comes to healthy agingSUBSCRIBE & CONNECTDon’t miss future episodes packed with supplement science and practical longevity insights.✅ Subscribe to the NatureCity YouTube channel🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform💬 Comment below with your biggest takeaway from this episodeExplore NatureCity supplements at 👉 https://www.naturecity.comFOLLOW USInstagram: @NatureCitySupplementsFacebook: NatureCity Supplements#NatureCityPodcast #Longevity #HealthyAging #VitaminD #Omega3 #Tocotrienols #Telomeres #AntiAgingScience #HealthSpan #SupplementScience

  12. 124

    Do Coffee & Tea Affect Bone Health?

    Is your daily coffee helping you… or quietly harming your bones? And could tea actually strengthen them?In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli revisits a popular question from a past episode: Is caffeine bad for bone health? This time, he breaks down new research published in late 2025 that followed nearly 10,000 women over age 65 for a decade — revealing some surprising differences between coffee and tea when it comes to bone mineral density.Carl explains why moderate coffee intake is usually safe, when it can become a concern (especially for postmenopausal women), and why tea — particularly green and white tea — may actually support stronger bones thanks to powerful polyphenols. He also shares practical, realistic strategies for protecting bone health without giving up your morning cup of coffee.Finally, Carl explains why bone health requires far more than calcium alone, and how NatureCity’s Tru Osteo® and Tru Osteo Plus® formulas are designed to support not just slowing bone loss — but potentially improving bone density over time.If you care about aging well, staying active, and keeping your bones strong for the long haul, this episode is a must-listen.WHAT YOU’LL LEARNWhat the newest long-term study reveals about coffee, tea, and bone densityWhy tea drinkers showed higher bone mineral density over 10 yearsWhen coffee consumption may negatively affect bone healthHow caffeine impacts calcium absorption (and why the effect is smaller than you think)Why postmenopausal women and low-calcium diets need extra cautionThe surprising role alcohol plays in worsening coffee’s bone effectsHow tea polyphenols and catechins support bone-building activitySmart ways to enjoy coffee while protecting your bonesWhy calcium alone isn’t enough for strong, healthy bonesHow Tru Osteo® and Tru Osteo Plus® support comprehensive bone healthSUBSCRIBE & CONNECTDon’t miss future episodes packed with supplement science and practical wellness insights.✅ Subscribe to the NatureCity YouTube channel🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform💬 Comment below with your biggest takeaway from this episodeExplore Tru Osteo® and Tru Osteo Plus® at 👉 https://www.naturecity.comFOLLOW USInstagram: @NatureCitySupplementsFacebook: NatureCity Supplements#NatureCityPodcast #BoneHealth #CoffeeAndBones #TeaBenefits #HealthyAging #Calcium #VitaminD #VitaminK2 #OsteoporosisPrevention

  13. 123

    The PEA Advantage: Joint Comfort, Faster Recovery, Sleep & Stress Support

    Joint discomfort, sore muscles, restless nights, and being overwhelmed by daily stress seem like separate challenges — but did you know your body naturally makes a nutrient that offers support for all of them?In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a deep dive into PEA (palmitoylethanolamide)—a naturally occurring fatty compound your body uses to manage discomfort, stress, and support a healthy inflammation response.Carl explains how PEA levels tend to decline with age (when we need PEA most), why most PEA supplements fall short, and how the best studied form of PEA, called Levagen+, overcomes absorption challenges and delivers results using the novel LipiSperse delivery technology. With over 14 published human studies, Levagen+ has been shown to support joint comfort, flexibility, muscle recovery, sleep quality, cognitive performance, immune health, and more.This is why we made Levagen+ a cornerstone ingredient in TrueJoint FLX, NatureCity’s premium joint formula, which was designed to help you start feeling better within days — and help keep you mobile and active with better joint function over time.If you want to support joint health, recover faster, sleep better, and support long-term resilience as you age, this episode is a must-listen.WHAT YOU’LL LEARNWhat PEA is and how your body naturally uses itPEA production declines with age — so supplementation makes senseWhy Levagen®+ is the best PEA for supplementsResearch-backed benefits for joint comfort and flexibilityHow Levagen+ supports faster muscle recovery and performanceThe role PEA plays in sleep quality, stress support, and cognitionEmerging research on immune, gut, metabolic, and menstrual supportWhy NatureCity includes Levagen+ in its TrueJoint FLX formulaTIMESTAMPS 0:00 – Welcome & why PEA deserves attention1:04 – What PEA is and where it comes from1:51 – PEA levels decline with age2:15 – The absorption problem with standard PEA supplements2:38 – Why Levagen®+ is different3:02 – LipiSperse® technology & absorption benefits3:30 – Joint comfort, stiffness, and flexibility research4:40 – Muscle recovery, soreness, and performance support5:42 – Sleep quality, stress balance, and nervous system support6:15 – Cognition, BDNF, and mental alertness findings6:58 – Heart rate variability support & stress resilience7:21 – Emerging research: menstrual comfort, gut & metabolic health8:04 – Final thoughts & where to learn more SUBSCRIBE & CONNECTDon’t miss future episodes packed with supplement science and practical wellness insights.✅ Subscribe to the NatureCity YouTube channel🎧 Listen on Spotify, Apple Podcasts, and more💬 Comment below with your biggest takeaway from this episodeExplore the full TrueJoint FLX formula at https://www.naturecity.comFOLLOW USInstagram: @NatureCitySupplementsFacebook: NatureCity Supplements#NatureCityPodcast #PEA #LevagenPlus #JointHealth #MuscleRecovery #SleepSupport #StressSupport

  14. 122

    Keeps Your Skin Hydrated – With Less Hair Loss Too

    Skin creams and serums can only do so much to keep your skin and hair looking their best. Support starts from within your body.This is especially true when it comes to reinforcing your skin’s moisture barrier and protecting hair cuticles with ceramides.In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli introduces Ceramosides®—a plant-based, gluten-free ceramide supplement that’s changing the way we support skin and hair health.Carl explains how Ceramosides® works from within to help increase skin hydration and elasticity, while reducing the appearance of fine lines and wrinkles. More recently, Ceramosides®  has also been shown it can help create a healthier scalp environment that supports stronger, fuller-looking hair, and reduces normal hair loss. Backed by five published scientific studies and a new consumer trial with 95 men, this episode is a must-listen if you’re interested in aging more gracefully, reducing hair shedding, or optimizing your skincare routine.You'll also find out why Ceramosides® is uniquely effective compared to other ceramide ingredients - and how it perfectly complements other researched ingredients like keratin and collagen in NatureCity’s new TrueNuGrow+ Hair & Skin Formula.If you want to keep your skin and hair looking its best, or you’re just curious about how science-backed supplement ingredients can boost your natural glow—this episode is for you.WHAT YOU’LL LEARNWhat ceramides are and how they help protect your skin and scalpHow Ceramosides® complements collagen, keratin, and topical creamsWhy this ingredient can be a game-changer for both men and womenWhat the recent studies reveal about skin hydration and appearance, hair loss and hair growthWhy NatureCity uses this patented ingredient in its TrueNuGrow+ formulaSUBSCRIBE & CONNECTDon't miss future episodes packed with supplement science and real wellness solutions. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and more 💬 Let us know your favorite part of this episode in the comments!Explore the full True NewGrow Plus formula at https://www.naturecity.comWELCOME TO THE NATURECITY YOUTUBE CHANNELHere you'll find expert-led insights into natural supplements and holistic health. Hosted by Carl Pradelli, NatureCity’s co-founder, our videos blend trusted science with practical advice to help you make informed wellness decisions.Each episode dives deep into key ingredients, emerging research, and proven supplement stacks designed to support energy, beauty, digestion, and longevity.FOLLOW USInstagram: @NatureCitySupplementsFacebook: NatureCity Supplements#NatureCityPodcast #Ceramides #HairSupplements #SkinHealth #Ceramosides

  15. 121

    Over 50% Of Berberine Supplements Tested Failed

    Fraudulent products are a real concern for supplement buyers.  The latest example of this was revealed in lab testing of top selling berberine supplements purchased on Amazon.  The results were pretty shocking with the majority of supplements seemingly containing less than 10% of the berberine claimed on the product label – with a couple containing none at all.In this eye-opening episode of the NatureCity Podcast, host and supplement industry veteran Carl Pradelli breaks down the findings and why if a supplement price seems too good to be true, it probably is.  You’ll also find out why solely relying on Amazon star ratings and badges may not protect you from purchasing a fraudulent supplement.Carl also dives into why berberine has become a target for fraudulent supplement makers: it's growing in popularity for supporting blood sugar, metabolic health, and weight management, but a high dose is required for results (which make it more costly to produce). This has opened the door for bad actors to cut corners.Carl also outlines the biological role of berberine, including how it supports AMPK enzyme activity, blood sugar metabolism, and insulin function. He also discusses GlucoVantage, a newer form of berberine (dihydroberberine) that offers superior absorption and far fewer stomach and gastrointestinal issues—making it a game-changer for anyone interested in the benefits of berberine.This episode doesn’t just warn you—it equips you. Learn how to spot quality supplements, why price matters, and how combining berberine with strength training can improve body composition and reduce fat storage.If you’re looking to optimize your supplement stack or protect your health investment, this episode is a must-listen. Don’t risk your health or waste your money. Subscribe for honest supplement insights and insider tips that protect your wellness journey.WHAT YOU’LL LEARNHow top selling berberine supplements failed a basic quality test.Why low prices often mean low quality. What makes berberine effective—and how to get the most from it.How new ingredient technology like GlucoVantage solves major challenges with berberine.Why combining berberine with exercise can help your body composition.Subscribe for weekly supplement science breakdowns and wellness tips.What’s your biggest takeaway from this episode? Let us know in the comments.Shop NatureCity’s TrueBerberine at https://www.naturecity.comWELCOME TO THE NATURECITY YOUTUBE CHANNELOn the NatureCity YouTube Channel, you’ll find expert-led insights into natural supplements and digestive health. With over 20 years of experience, Carl creates videos packed with practical, science-backed information to help you make informed health choices.Our channel provides in-depth overviews of our top supplements, like the TrueDYB formula. We break down how each ingredient supports digestive health, immunity, and overall wellness, so you can see exactly how our products are designed to maximize benefits. If you’re curious about what makes these supplements effective, we’ll guide you through the science and thought behind each one.Our videos cover essential digestive health topics, such as managing leaky gut and boosting nutrient absorption. You’ll find straightforward tips to support your gut health and better understand the role of supplements in your daily wellness. Each video simplifies complex nutritional concepts, explaining how popular ingredients interact to support your body’s natural functions.Subscribers also gain access to honest Q&A sessions and product reviews. If you have questions about a specific supplement or a health concern, we provide clear, direct answers to help you choose products that meet your needs. With real testimonials and our honest approach, you’ll feel confident about the supplements you choose.Beyond supplements, we share guidance for a balanced, holistic lifestyle. Our wellness videos offer actionable tips on diet, lifestyle adjustments, and strategies for boosting energy and longevity. We believe health goes beyond products, so we’re here to support your journey to better well-being.By subscribing to our channel, you’ll join a community that values transparency, quality, and above all, your health. Let NatureCity be your trusted source for reliable, science-based wellness information, helping you take meaningful steps toward a healthier life.FOLLOW NATURECITY ON SOCIAL MEDIAInstagram: https://www.instagram.com/NatureCitySupplements/Facebook: https://www.facebook.com/naturecitysupplements#NatureCityPodcast #SupplementScam #BerberineBenefitsKeywords: berberine supplement fraud, GlucoVantage, blood sugar support, supplement quality control, Amazon supplement reviews

  16. 120

    New Melatonin Study Raises Red Flags: What Does It Mean?

    A new study sponsored by the American Heart Association links long-term melatonin use to increased risk of heart failure and early death—but is the data trustworthy?  What does this mean for supplement users?In this episode, Carl Pradelli breaks down the controversial melatonin study making headlines and the potential issues with how the study was conducted.  Carl also shares his concerns with taking melatonin regularly or taking excessive amounts. He also reveals the spice that can be a better option as a supplement because it supports your body’s natural melatonin production process and has been shown to help increase sleep quality and mood upon awakening.Subscribe to stay ahead of the health curve. What You’ll Learn:The limitations of the “preliminary” results linking long term melatonin use to risk of heart failureThe significant flaws in the study structureOthe concerns with regular melatonin use A natural way to support your body’s own melatonin productionSupporting healthy melatonin levels without disrupting the sleep/wake cycleSubscribe for weekly natural health insights and supplement strategies.What do you think about melatonin—have you had a positive or negative experience? Drop your thoughts in the comments 👇Explore TrueZs and support natural melatonin production: https://www.naturecity.com#NatureCityPodcast #MelatoninRisks #SleepSupplements

  17. 119

    The Benefits of DE111: The Spore-Forming Probiotic That Delivers

    In this episode of The NatureCity Podcast, host Carl Pradelli, CEO and co-founder of NatureCity, explores the benefits of one of the best probiotic strain options available for supplements.  It’s a strain of Bacillus subtilis called DE111®.Carl explains how your gut is estimated to contain more than 100 trillion bacteria, which is why supplementing with a diverse group of probiotic strains may help you maintain a healthy balance of beneficial gut bacteria – which is believed to be foundational to good health.You’ll hear how DE111 stands apart from the more common Lactobacillus and Bifidobacterium probiotic strains (which are also important) by forming protective spores that ensure survival during manufacturing, storage, and digestion.DE111 has been the subject of much research, and Carl also details some of the key benefits highlighted in these scientific studies.  These benefits go beyond the expected digestive and immune health support.This episode is a must-listen for anyone interested in practical, science-based ways to improve digestion and strengthen the gut microbiome and wellness naturally.What You’ll Learn in This EpisodeHow DE111’s spore-forming structure protects it from moisture, oxygen and stomach acid. Why gut microbial diversity matters for long-term digestive and immune health.What makes Bacillus subtilis DE111 unique among probiotic strains.How DE111 can support digestion, regularity, nutrient absorption, and more. Why pairing TrueDYB with TrueLife PB can provide full-spectrum gut support.Links & ResourcesLearn more about True DYB (“Digest Your Best”) and True Life PB:https://www.naturecity.comSubscribe for weekly science-backed gut health insights:YouTube: NatureCity ChannelApple Podcasts | SpotifyWhat was your biggest takeaway from this episode? Share your thoughts in the comments below.About Carl PradelliCarl Pradelli is the co-founder and CEO of NatureCity, a trusted supplement company serving over 500,000 Americans for more than two decades. Through The Nature City Podcast, Carl shares science-driven insights on nutrition, gut health, and the pursuit of natural wellness.Calls to ActionSubscribe for weekly gut health and nutrition strategies at naturecity.comComment below with your experience using probiotics.#NatureCityPodcast #GutHealthTips #ProbioticScience

  18. 118

    Supplement Shopping Tip #3 – Understanding the Brand Owners’ Motivations

    Finding the right supplements and a brand you can trust can feel overwhelming. How do you know which ones truly care about your health? In this episode of the NatureCity Podcast, host and CEO Carl Pradelli shares his 3rd essential tip for buying dietary supplements: know who owns and runs the brand - and why the brand exists.Carl explains why transparency, integrity, and experience matter more than ever in a marketplace filled with counterfeit and fraudulent products, subpar formulas and low-quality imitators. You’ll learn how to spot red flags, avoid wasted money, and confidently choose quality supplements that help you.Whether you’re new to natural health or a long-time supplement user, this insider advice from a 24-year industry veteran helps you become a more informed and empowered consumer.Subscribe for weekly wellness tips.WHAT YOU’LL LEARN:• Why the people behind a supplement company matter.• Brands with nothing to hide, hide nothing, and share ingredient sources, manufacturing details, and consumer friendly policies.• Why it can take years in the industry to figure out who in the supply chain can be trusted, and deliver for you• How mergers, investor buyouts, and rebranding can change product quality almost overnight.• What the length of a money back guarantee reveals about a company’s confidence in its products.Don’t miss the earlier deep-dive:The #1 Tip for Choosing Quality Supplements: https://www.youtube.com/watch?v=lpXEJXxtnvUWhy the supplement manufacturer matters more than the brand: https://www.youtube.com/watch?v=fSRqjG-M8FY📣 CALL TO ACTION Visit https://www.naturecity.com to explore trusted, high-quality supplements backed by over 20 years of experience. Comment below with your biggest takeaway from Carl’s supplement-buying tips!#NatureCity #SupplementShoppingTips #DietarySupplements #WellnessPodcast #NaturalHealth #SupplementAdvice #HealthyLiving

  19. 117

    New Science: OptiMSM Boosts Muscle Recovery

    Staying active is key to good health.  But it’s hard to do if your muscles don’t recover quickly and soreness lingers. New scientific evidence shows how OptiMSM can help your body recover faster.In this episode of the NatureCity Podcast, host and CEO Carl Pradelli dives into the latest research with OptiMSM, which is a premium form of MSM (methylsulfonylmethane). Find out how this sulfur-rich compound helps your body bounce back faster, reduce oxidative stress, and support healthy post-exercise immune and inflammation responses.Whether you're a runner, gardener, weekend warrior or just trying to stay fit, this natural recovery aid can help your feel better today and get you ready for tomorrow.Even better, there are many other ways OptiMSM can help you, especially for hair, skin and joint health because it plays a vital role in supporting collagen, keratin, and connective tissue throughout the body. Tune in to discover how OptiMSM may help you.Subscribe for weekly wellness tips.✅ WHAT YOU’LL LEARN:OptiMSM benefits for muscle recovery and reducing post-exercise soreness.Benefits can be experienced with just 500–1000 mg/day of OptiMSM.Study results from half-marathon runners and why they matter to you.How TrueNuGrow+ delivers pure OptiMSM in daily servings.Benefits of 13 powerful ingredients in one supplement.Don’t miss the earlier deep-dive: Episode 110 – OptiMSM for Hair, Skin & Joints⏱️ TIMESTAMPS:0:00 Welcome + Why Recovery Matters More With Age1:40 What Is OptiMSM? The Sulfur Containing Compound Behind Faster Recovery3:00 New Study Breakdown – OptiMSM vs. Placebo in Marathon Runners4:55 Biomarker Improvements – How MSM Reduces Oxidative Stress and Muscle Damage6:00 Surprising Results at Lower Doses (500–1000mg)7:10 OptiMSM Can Work for Everyday Movement, Not Just Athletes8:00 Recap 📣 CALL TO ACTION Visit https://www.naturecity.com to explore OptiMSM.

  20. 116

    More Evidence of Tocotrienol Brain Benefits – Why Your Vitamin E Supplement May Be Incomplete

    You’ve heard of vitamin E—but have you heard of tocotrienols? These powerful compounds are also part of the vitamin E family, but hard to get from the food we eat, and are usually missing from regular vitamin E supplements.  Research is finding tocotrienols may be more beneficial than alpha-tocopherol (the more well-known member of the vitamin E family) for certain key areas of our health – including aspects of brain, heart, and liver function.In this episode of the NatureCity Podcast, host and CEO Carl Pradelli highlights key findings from two newly published studies showing the potential of tocotrienols protecting brain cells supporting memory and focus, and promoting healthy brain aging.Carl explains the crucial difference between tocopherols and tocotrienols, and why the latter may be up to 60x better at fighting oxidative stress. This episode is a must-listen if you want to stay mentally sharp, focused, and vibrant through the years. Discover why NatureCity’s TrueE formula includes all four tocotrienols along with alpha-tocopherol — all naturally sources, to give your body the best of what vitamin E has to offer.Tocotrienols may be the brain's best-kept secret. Learn how to unlock their power—subscribe now!What You’ll Learn:The lesser-known members of the vitamin E family (vitamin E isn’t just alpha tocopherol)How tocotrienols support memory, learning, and brain cell formationWhy most supplements are missing these powerful nutrientsWhat the latest studies say about “super” vitamin E and cognitive agingHow NatureCity’s TrueE formula delivers the best vitamin E has to offer💡 Enjoy this episode? Subscribe and leave a review on YouTube or your favorite podcast app.🔎 Learn more about TrueE and tocotrienols at https://www.naturecity.com📧 Share this episode with a friend who’s focused on healthy aging!#BrainHealth #Tocotrienols #VitaminESupplement #CognitiveSupport #HealthyAging

  21. 115

    Why Omega-3s Matter for Brain Health

    In this week’s episode of the NatureCity Podcast, we explore the importance of the omega-3 fatty acids DHA and EPA for brain health and cognitive function – particularly as we age.NatureCity co-founder and CEO, Carl Pradelli, covers what DHA and EPA actually do for your brain and why Americans, on average, only get about 10% of the ideal amount of these omega-3s daily from diet.Taking a supplement is a smart way to help bridge this shortfall. Carl explains what you need to look for to effectively boost your omega-3 levels and get the most for your money. 👉 Don’t forget to like, comment, and subscribe to stay connected with future episodes!What You’ll Learn in This Episode:Why DHA and EPA are critical for brain structure and functionHow Omega-3s support memory, learning, focus, and emotional balanceWhat research shows about Omega-3 levels and brain performance as we ageWhy most people fall short on Omega-3 intake from dietHow the Omega-3 Index blood test works and what it revealsThe difference absorption makes in supplement effectivenessThe ideal fish oil supplement formulation for purity, freshness, sustainability and promoting healthy omega-3 levelsFollow NatureCity on Social MediaInstagram: https://www.instagram.com/NatureCitySupplements/ Facebook: https://www.facebook.com/naturecitysupplements

  22. 114

    Tart Cherry: The Muscle Recovery Secret of World-Class Athletes

    Why were many elite Tour de France cyclists drinking tart cherry juice during this grueling event?  In this episode of the NatureCity Podcast, host Carl Pradelli explores what makes these cherries unique – and how they can aid joint and muscle recovery, and support performance during physical activity.Carl also details the premier form of tart cherry powder for supplements, called CherryPure®.  You’ll hear how it can help support a healthy inflammation response, healthy uric acid levels, and other scientific findings.  Whether you’re training, gardening, or just keeping up with a busy lifestyle, tart cherry can help you bounce back faster and feel your best.Our TrueBerry7 drink powder is formulated with CherryPure and six other high potency super fruit extracts, each offering unique benefits. You can find out more about TrueBerry7 here:  https://www.naturecity.com/products/true-berry-7👍 Like this video 💬 Comment with your experience using tart cherry🔔 Subscribe to the channel so you never miss an episode of the NatureCity Podcast#TartCherry #MuscleRecovery #AthleteSupplements #TrueBerry7 #MontmorencyCherries #NatureCity #JointHealth #InflammationSupport #TourdeFrance

  23. 113

    Sicilian Beauty Secret Offers Better Skin from Within

    In this episode of the NatureCity Podcast, host Carl Pradelli sits down with Jodi-Ann Blackwood from BIONAP USA to discuss the award winning Red Orange Complex® from Sicily, Italy.  A blend of three Sicilian oranges, the Red Orange Complex® was recently named the 2025 NutraIngredients USA Ingredient of the Year in the Beauty from Within category, one of the hottest areas in the supplement world.Tune in to discover what makes this Sicilian blood orange extract so powerful and why this blend is considered a breakthrough for skin health, healthy aging, and overall wellness. Jodi-Ann and Carl break down the science, sustainability, and the incredible benefits of this antioxidant-rich ingredient.In This Episode, You’ll Learn:Why Sicily’s Mount Etna creates the perfect growing conditions for ultra-potent blood oranges.What makes Red Orange Complex® different from regular oranges and other extracts?Insights from 8 published studies, including how it can help:Skin hydration, elasticity, and wrinkle depth.Protect against environmental stressors and reduce oxidative stress.Reduce appearance of dark spots.Relieve menopausal symptoms and improve quality of life.Why just 100mg per day starts delivering results in as little as 2 weeks.What won the judges over and sealed the Ingredient of the Year award.Red Orange Complex® is featured in NatureCity’s own TrueNuGrow+ Hair & Skin Formula.👉 If you’re passionate about natural wellness, healthy aging, and looking your best, this is an episode you don’t want to miss!🔔 Subscribe & Stay ConnectedDon’t miss future episodes of the NatureCity Podcast!🌐 Visit us at: NatureCity.com

  24. 112

    Why Magnesium Matters for Your Health

    Magnesium is one of the most important minerals for your health—and one of the hardest to get enough of from diet alone. It’s estimated that 75% of adults in the U.S. fail to reach the Recommended Daily Allowance (RDA).  This isn’t just unfortunate, it’s a true health concern. In this episode of the NatureCity Podcast, CEO and co-founder Carl Pradelli breaks down why magnesium diet shortfalls are such a widespread issue, why magnesium is so important, and signals from your body that your magnesium intake may be too low.  You’ll also hear where some common forms of magnesium in supplements come up short and why Magnesium Bisglycinate Chelate is the gold standard. Carl also shares his personal experience (and his wife Beth’s story) about how this form of magnesium made a real difference in their lives.👉 Whether you struggle with muscle cramps, sleep troubles, mood swings, or simply want to feel and function your best, this episode will help you understand how to get the magnesium your body truly needs.Key Takeaways:Magnesium supports over 300 biochemical reactions in the body.Most people only get 150–300 mg/day from food (well below the RDA).Deficiency can show up as poor sleep, muscle cramps, low energy, or mood changes.Magnesium Bisglycinate Chelate is gentle, highly absorbable, and effective.TrueMagnesium provides a clean, convenient way to meet your daily needs.Learn more about True Magnesium and True Zs: https://www.naturecity.com/👍 Like this video if you found it helpful🔔 Subscribe & hit the bell so you never miss an episode💬 Comment below: Have you tried supplementing with magnesium? What differences have you noticed?

  25. 111

    How Your Probiotic Packaging Could Be Sabotaging Your Gut Health

    In this week’s episode of the NatureCity Podcast, Carl Pradelli—CEO and Co-founder of NatureCity— tackles an often overlooked, but surprisingly critical topic that could significantly impact the potency and effectiveness of your probiotics: how they’re packaged.Many users don’t realize that elements like moisture, heat, and air exposure are the enemies of live probiotic cells - and can drastically reduce the potency of your probiotic supplement before you’ve even opened the bottle. And it gets worse – each time you open the cap to take a capsule, moisture and air enter the bottle and further destroy probiotic CFU (number of probiotic cells) counts.Carl reveals the innovative new bottle that you should seek out for your probiotic supplements. Research studies have found it’s far superior to other common packaging options in protecting live probiotics – even after you begin taking the product.In this episode, you’ll find out:Why traditional probiotic packaging (like standard bottles and blister packs) may not offer enough protectionHow the Activ-Vial bottle technology helps preserve potency—even after openingWhat scientific studies say about probiotic degradation in the various probiotic packaging optionsWhy NatrueCity switched to the Activ-Vial bottle for its premium TrueLife PB probiotic/prebiotic supplement blendOther important “must have” supplement features that help ensure the probiotics “arrive alive” and maximize benefits and health impactIf you’re relying on probiotics to support your immune system, digestive health, gut balance, or overall wellness, you don’t want to miss this episode.Learn more or shop TrueLife PB: https://www.naturecity.com📩 Have questions? Contact us anytime at [email protected]🔔 Subscribe for more science-backed supplement insights every week💬 Comment below: Have you ever thought about how your probiotic is packaged?

  26. 110

    Not Just for Joints - The Overlooked Beauty Mineral

    In this episode, Carl Pradelli unpacks the surprising power of methylsulfonylmethane (MSM), especially in its ultra-pure OptiMSM® form.  OptiMSM® provides sulfur, which may not sound exciting, but is essential for life and aging well.  Traditionally, taken for joints, immune heath and antioxidant support, OptiMSM® might be your secret weapon for glowing skin and healthier looking hair.Often called the “beauty mineral,” MSM is needed to help the body produce collagen, elastin, keratin, and hyaluronic acid — essential compounds for youthful looking skin, resilient nails, and thicker, shinier hair.OptiMSM® helps your body inside and out. In addition to helping your appearance, it supports your body’s key antioxidant, glutathione, to help reduce oxidative stress, and can help you stay active with greater joint comfort and faster muscle recovery from activities.OptiMSM® is one of the cornerstone ingredients in NatureCity’s advanced TrueNuGrow+ hair and skin formula.What You’ll Discover:What MSM is and why it’s essential for beauty and joint healthHow it supports collagen, keratin, and hyaluronic acid production naturallyWhy OptiMSM® is the best choice for supplementsStudy-backed results for smoother skin, shinier hair, and stronger nailsHow OptiMSM® enhances joint and muscle recovery, reduces aging signs, and boosts glutathioneLike what you heard? Subscribe on YouTube and drop a comment if you’ve tried OptiMSM® or TrueNuGrow+!🔗 Learn more: https://naturecity.com 🎧 Listen on Spotify, Apple, or your favorite podcast platform 📩 Have questions? Reach out—we’d love to hear from you.

  27. 109

    Flavonoids for Longevity: Extend Your Healthspan Naturally

    Is your diet unknowingly limiting your healthspan – and perhaps even your longevity?In this episode of the NatureCity Podcast, host and NatureCity CEO Carl Pradelli breaks down compelling new research from scientists in the UK and Australia, published in Nature Food, revealing that not just the quantity—but the diversity—of flavonoids in your diet can play a critical role in how long and how well you live.Using data from over 125,000 adults in the UK Biobank initiative, this study found that higher, more diverse flavonoid intake was linked to improved heart, immune, blood sugar, and cognitive health outcomes—and even reduced mortality rates.Carl reviews what this means for your daily nutrition, how to make smarter choices when selecting foods and supplements, and how NatureCity's approach supports this science-backed strategy for healthy aging.What You’ll Learn in This Episode:What flavonoids are and how they support healthy agingWhy flavonoid diversity matters more than just quantityWhich foods are rich in different types of flavonoidsHow a single-source diet (like relying only on tea) can limit benefitsWhy supplement ingredient variety may be key to better healthspan outcomesHow the flavonoids in the TrueBerry7 formula support multiple systems in the bodyLearn more about the TrueBerry7 formula and its scientifically supported ingredients:https://naturecity.comSubscribe to the channel for future episodes and actionable health tips.

  28. 108

    The Hidden Hero Behind Your Supplements with Lauren Samot of Vitaquest

    In Tip #2 for supplement shopping, Carl Pradelli, co-founder and CEO of NatureCity, is joined by Lauren Samot, Commercial Innovation Leader at Vitaquest International to discuss the importance of knowing the actual manufacturer of the supplements you’re taking. The supplement brand is usually not the manufacturer because making supplement products is a highly specialized (and regulated) activity requiring many layers of expertise to deliver quality and safe products you can trust.What You'll Learn:Why the manufacturer behind your supplement brand matters more than you may have known.What standards and certifications like cGMP, FSSC 22000, and NSF can actually mean for the health of you and your loved ones. The importance of robust in-house labs and protocols to protect against adulteration, contamination, and dosage errors.The transparency practices that distinguish trustworthy supplement brands and manufacturers.Questions you should ask before buying any supplement.Behind the Scenes of Supplement SafetyWhile most consumers focus on the supplement brand, it's the manufacturer who often plays a pivotal role in determining product quality. In this episode, Lauren and Carl pull back the curtain on the manufacturing world—from rigorous testing protocols and audits to third-party certifications and in-house labs. Lauren breaks down why it's vital to know where and how your supplements are made, emphasizing transparency and trust.You'll learn about the manufacturing tiers that separate premium producers like Vitaquest from less capable (and often questionable) operations, and why third-party testing alone isn't enough. Carl and Lauren discuss real examples of how early detection in quality labs prevents low quality and potentially harmful products from reaching your home. Plus, they reveal why branded, scientifically studied ingredients are your best bet for effectiveness and safety.Like what you heard? Subscribe on YouTube, Spotify, or Apple Podcasts. Leave a review to help others discover smarter supplement shopping tips!Links & Resources:Website: https://naturecity.com Email: [email protected] Instagram: https://www.instagram.com/naturecitysupplements/===== ABOUT NATURECITY ===== NatureCity is dedicated to helping people live healthier, longer lives through transparency, education, and premium supplements. Founded over 20 years ago, we make products we personally take and are proud to recommend to our loved ones. Learn more at https://naturecity.com.

  29. 107

    This Marine Collagen Breakthrough Works at Just 500mg

    In this eye-opening episode, Carl Pradelli, co-founder of NatureCity, dives into the benefits, science, and sourcing of Cartidyss, a marine collagen breakthrough sourced from upcycled wild fish cartilage. Special guest Jocelyn Bérubé, EVP of Scientific Affairs at innoVactiv, unpacks why this clean, sustainable, and research backed collagen stands out from the crowd—offering powerful skin, hair and nail benefits at just 500mg per day.What You’ll Learn:What sets Cartidyss apart from bovine and porcine collagen and other marine sources.How the combination of collagen peptides and GAGs like hyaluronic acid benefit your skin, joints, and hair.Research results showing wrinkle reduction, hydration improvements, and more youthful looking skin.Why sourcing, hydrolysis and digestibility, and purity matter more than dosage.The sustainable story behind Cartidyss from upcycled skate cartilage from Brittany, France.This is more than just another supplement chat—it’s a masterclass in how to choose a collagen supplement that really works for skin and joint health. Whether you’re in your 30s, 60s or older, this episode provides actionable insights on choosing the best collagen product.Subscribe for more inside wellness insights!Loved this episode? Subscribe and leave us a review on Apple Podcasts or Spotify! Find out more about TrueNuGrow+, featuring Cartidyss: https://naturecity.com

  30. 106

    The Truth About Lutein: Vision, Brain Power & Its Essential Partner

    Think lutein is just for your eyes? Think again. In this deep-dive episode, Carl Pradelli, co-founder and CEO of NatureCity, unpacks everything you didn’t know about this essential carotenoid—and why your brain and eyes might be silently craving more of it. Plus, it’s not a solo performer.  To get the most from supplements with lutein, you need two other nutrients from the same antioxidant family.Find out the best natural source of these nutrients for supplements, misconceptions about food options with these nutrients, and what the science found about supplementing with lutein and its essential nutrient partners.What You’ll Discover:What lutein, zeaxanthin, and meso-zeaxanthin actually do.Why most diets fail to deliver enough to maintain healthy vison and cognitive function.Foods that seem rich in lutein and zeaxanthin —but aren’t.How lutein can help protect your brain and eyes from digital strain.What the latest studies say about supplement ingredients like the Lutemax 2020 in TrueVision.Lutein is a powerhouse antioxidant often associated with eye health, but this episode reveals it also plays a crucial role in cognitive function. Carl breaks down why it’s so difficult to get enough lutein, zeaxanthin, and meso-zeaxanthin from food — especially in today’s processed food world — and how the USDA’s early data might still be leading to confusion in your nutrition choices.You’ll learn how lutein and its partner nutrients can help shield your eyes from blue light damage caused by screens, supports macular pigment density, and may even boost memory and stress resilience. Carl explains why foods thought to provide lutein AND the zeaxanthins actually don’t, and some better diet options for these nutrients (which are hard to get from diet alone).The episode also highlights Lutemax 2020, a science backed supplement ingredient that delivers all three essential carotenoids from a single marigold flower source — and why consistent intake may be your best strategy for long-term vision and brain support.Liked this episode? Subscribe to our YouTube channel and leave a review on Apple Podcasts or Spotify! https://www.youtube.com/@naturecitysupplements 🛒 Shop TrueVision with Lutemax 2020 & Affron Eye Saffron Extract: https://naturecity.com

  31. 105

    Tip #1 for Choosing Quality Supplements: Branded Ingredients over Generics

    Do you find shopping for supplements hard or frustrating?  Worried you’re going to choose the wrong one or it’s not going to help you? Or worse – you’ll be wasting your money?In this episode of the NatureCity Podcast, CEO Carl Pradelli kicks off a new series on how to choose high quality supplements and avoid low-quality or fraudulent supplements. Tip #1: Choose branded ingredients over generic supplement ingredients. Carl breaks down what branded ingredients are, why they matter, and how they help ensure potency, purity, and protection from fraud.  You'll also hear why all branded ingredients are not the same (or automatically good to take) and find out the standards companies like NatureCity use to ensure its customers are getting the very best in every capsule or scoop of powder.Branded vs. Generic IngredientsWhy Quality Supplements Use Branded IngredientsCross-Checking to Prevent Fraud in the Supplement Industry👉 Learn more at https://www.naturecity.com🎧 Subscribe on Spotify and Apple Podcasts📺 Subscribe for more tips on supplement quality

  32. 104

    Avoid Fake Aloe Vera! 5 Tips for Picking a Supplement that Actually Works

    In this episode of the NatureCity Podcast, host Carl Pradelli, CEO and co-founder of NatureCity, breaks down his 5 essential tips to help you spot premium Aloe vera supplements and steer clear of products lacking potency or containing outright fake or adulterated Aloe. You’ll hear why USDA organic certification is especially important for Aloe vera, and the importance of choosing Aloe vera made with freeze-drying methods to preserve the Aloe vera “nutrient orchestra” and maximize benefits. Plus, the best way to ensure your Aloe vera isn’t really maltodextrin or cut with starch.  If you're using Aloe vera for gut health, heart and metabolic health, joint health or to improve the appearance of your skin — this one's for you!👉 Subscribe for weekly supplement tips!👉 Leave a review on your favorite streaming platform.Check out the featured products:🌿 TrueAloe Capsules🍹 AloeCran Drink Powder💧 TrueAloe Gel (Topical)

  33. 103

    Top 3 Gut Health Benefits of Aloe Vera

    Discover how aloe vera supports gut health—from soothing your stomach to helping enhance nutrient absorption.In this episode of the NatureCity Podcast, host Carl Pradelli breaks down the top 3 digestive and gut health benefits of Aloe vera – one of the most popular botanicals used in supplements. Find out how Aloe vera can help balance stomach acid, improves nutrient absorption, and supports prebiotic activity and intestinal health to help support your digestive health. Carl also shares research-backed insights and reveals why certain Aloe vera supplements may not work – and gives a sneak peek into what to look for in a quality aloe supplement. Perfect for health-conscious listeners eager to optimize their digestion and gut health naturally. 👉 Subscribe to our YouTube channel for more natural health tips: https://www.youtube.com/@naturecitysupplements ⭐ Love the show? Leave us a review on Apple Podcasts or follow us on Spotify!Links:Check out True Aloe: https://www.naturecity.com/products/truealoe-organic-aloe-vera Check out AloeCran: https://www.naturecity.com/products/aloe-cran

  34. 102

    Taking Regular Vitamin E? This Upgrade is Better

    In this episode, Carl Pradelli, CEO and Co-founder of NatureCity, discusses some little-known facts about vitamin E. For starters, vitamin E is not a single substance, there are eight compounds that make up the vitamin E family – and science is showing the form that makes up most of our vitamin E intake (and used in most supplements) may be much less powerful and beneficial than some of the others.Carl also reveals why you’re shortchanging your health if you take synthetic vitamin E – and how to tell if your supplement is made with synthetic vitamin E.You’ll also hear about some of the latest research discoveries with the combination known as “Super Vitamin E.” This combines the five most potent forms of vitamin E, and research indicates it may offer valuable health benefits not seen with just the “regular” vitamin E (which is called alpha- tocopherol), Carl summarizes some of these findings for the brain, liver and cardiovascular system – and tells you where to find the Super Vitamin E!What You’ll Learn in This Episode✅ Why synthetic Vitamin E supplements fall short ✅ The simple label trick to spot natural vs. synthetic Vitamin E✅ Why tocotrienols may be up to 60x more powerful than regular Vitamin E✅ How Super Vitamin E supports brain function, cardiovascular health, and liver protection✅ The #1 vitamin E supplement you should consider: TrueE with EVNol SupraBioLearn more about TrueE: https://www.naturecity.com/

  35. 101

    Omega-3 Breakthroughs: New Research on Heart, Bone & Aging Health

    Welcome to this episode of the NatureCity Podcast, where host and CEO Carl Pradelli dives deep into the latest scientific discoveries about Omega-3s and why these EPA and DHA fatty acids are so vital for your health. Backed by over 50 years of research, science continues to show the value of Omega-3s for cardiovascular health, bone strength, and longevity.In this episode, Carl reviews three new groundbreaking studies on the EPA and DHA Omega-3s, covering how they may keep circulating vesicles in a heathy range (excess amounts can impede blood flow and lead to blood clots), support bone health (especially in postmenopausal women), and slow biological aging by positively impacting PhenoAge scores.You’ll also learn what to look for in a high-quality fish oil supplement, including potency, purity, sustainability, and absorption. Carl explains why NatureCity’s TrueOmega-3supplement meets all these criteria and more—offering a highly bioavailable source of Omega-3s you can trust.What You’ll Learn from This Episode:✅ The latest study from the British Journal of Nutrition finds that fish oil supplements may reduce harmful levels of circulating vesicles that impact heart health.✅ Research from the journal Frontiers in Nutrition shows Omega-3 intake is linked to better bone health bones, especially in adults under 60.✅ New findings reveal that Omega-3s can slow biological aging by improving blood markers that calculate your PhenoAge.✅ Why EPA might be more important than DHA for circulating vesicle control—but both are essential for good health.✅ How NASA’s astronaut bone loss research helped kickstart Omega-3 bone health studies.✅ What makes a premium fish oil supplement: potency (EPA/DHA content), purity, sustainability, and bioavailability.👉 If you're serious about optimizing your heart, bone, and aging health with Omega-3s, don’t miss this episode.📌 Subscribe for more science-backed supplement education every week.

  36. 100

    enXtra Thai ginger: Alertness, Energy & Focus Without Caffeine Crash

    Looking for a natural way to boost alertness and sustain mental energy throughout the day without relying on caffeine? We are too! In this special 100th episode of the NatureCity Podcast, co-founder and CEO Carl Pradelli takes you behind the science and findings with enXtra—a cutting-edge plant-based ingredient from Thai ginger, which is featured in the new TrueMind supplement.This innovation is timely because increasing mental energy for better cognitive performance topped the charts in a recent survey of consumer health goals.If you're struggling with mental fatigue, lack of focus, making too many mistakes or afternoon crashes, this episode will show you how to level up your productivity with the powerful enXtra plant extract – without resorting to more caffeine.Carl breaks down the research behind enXtra, including how it stacked up in a head-to-head study versus caffeine, and shares how this caffeine-free focus supplement can improve alertness, attention, calmness, and accuracy for at least 5 hours — without the jitters or crashes.What You’ll Learn in This Episode:✅ What enXtra (Alpinia galanga / Thai ginger) is and how it works✅ How enXtra compared to caffeine in head-to-head scientific study✅ Why TrueMind can help you stay energized and focused for 5+ hours✅ How enXtra supports dopamine activity—your brain’s motivation molecule✅ Personal User experience: What were the benefits?✅ How enXtra can improve accuracy and mental clarity within 30 minutes✅ Avoiding the caffeine crash ✅ How Carl uses enXtra + caffeine strategically for peak focus✅ Research found enXtra doesn’t affect sleep, blood pressure, or heart rate—even at double the dose✅ What makes TrueMind ideal for busy professionals, and adults of all agesTrueMind is now available at https://naturecity.comQuestions? Contact us anytime. And don’t forget to subscribe and follow us on Apple Podcasts or Spotify to stay up-to-date on future episodes!

  37. 99

    Best Supplement for Focus and Mental Energy – Without Caffeine

    Struggling with mental fatigue, inability to focus, or low afternoon energy? In this episode of the NatureCity Podcast, co-founder Carl Pradelli introduces a powerful new supplement that’s changing the game for clean, sustained mental clarity and performance: TrueMind.Designed for professionals, young adults and others seeking to boost daytime focus, attention, mental energy, productivity, and stress resilience—without caffeine—the ingredients in TrueMind start working in as little as 30 minutes, with the effects lasting up to 5 hours, to help you stay sharp and productive all day long.Whether you're battling midday brain fog, overwhelmed and constantly interrupted at work, or just want to reduce your caffeine dependency and sleep issues, this episode gives you the science, the story, and the solution.What You’ll Learn in This Episode:✅ Why TrueMind is the best supplement for focus and cognitive performance✅ How it provides natural energy without caffeine or crashes✅ Carl’s personal 6-month experience testing the formula✅ The real reason you can’t stay focused in today’s workplace—and how TrueMind helps✅ The problem with relying on caffeine for productivity✅ How TrueMind promotes long-lasting mental performance and fewer mistakesWhy Try TrueMind?Helps you think clearer, stay calm, and get more done.No caffeine, no jitters, no late-day crashes.Backed by real published scientific research.Supports adults of any age facing modern distractions or need age-related cognitive support.TrueMind is now available at https://naturecity.comQuestions? Contact us anytime. And don’t forget to subscribe and follow us on Apple Podcasts or Spotify to stay up-to-date on future episodes!

  38. 98

    Ashwagandha for Bone Health? New Study Finds Sensoril Can Help

    Stress and elevated cortisol may be silently and slowly hurting your bone health. A new study indicates Sensoril ashwagandha may offer help.In this episode of the NatureCity Podcast, host Carl Pradelli explores groundbreaking new research on Sensoril — a powerful extract from the ashwagandha plant, and a natural adaptogen that helps bring the body back into balance. Sensoril is best known for helping the body better cope with stress and managing cortisol levels.  This new study with post-menopausal women indicates Sensoril can help support bone health and healthy bone formation, and ease certain post-menopausal symptoms.Carl also shares how NatureCity was the first supplement company to include cortisol support in a bone health supplement many years ago – with the inspiration for TrueOsteo+ stemming from the challenges his own family faced with bone loss. If you’re looking for natural bone health support, want help protecting against stress-related bone loss in the fast-paced modern 21st century world, or are curious about adaptogenic herbs like Ashwagandha, this episode is packed with essential takeaways and insights.What You’ll Learn in This Episode:✅ Sensoril Ashwagandha helps maintain healthy cortisol levels, a crucial factor for supporting bone health.✅ New research confirms Sensoril can support markers of healthy bone formation, bone turnover and help with menopause-related symptoms.✅ TrueOsteo+ was created to address numerous bone health challenges, including elevated cortisol levels, using a science-backed, plant-based formula.📣 Want to Learn More?Visit https://naturecity.com or find TrueOsteo+ on Amazon.Questions? Contact us anytime. And don’t forget to subscribe and follow us on Apple Podcasts or Spotify to stay up-to-date on future episodes!

  39. 97

    New Study Verifies Urinary Tract Benefits of Pacran Cranberry

    Can cranberry supplements really help reduce recurring UTIs? Yet another study with the Pacran cranberry powder says yes!In this episode of the NatureCity Podcast, host and CEO Carl Pradelli breaks down the results of a new published research study showing the powerful effects of the Pacran whole cranberry powder in supporting urinary tract health — especially for women prone to recurring UTIs.If you’ve been told to drink cranberry juice for urinary tract health support, this episode explains why that advice may not be ideal. But Pacran, a potent, whole fruit cranberry supplement, is a science-backed alternative that can work without the added sugar and calories of cranberry juice.What You’ll Learn in This Episode:✅ What the latest research reveals about Pacran’s role in reducing recurrent UTIs by over 50%✅ How Pacran compares to traditional cranberry juice and isolated PACs (proanthocyanidins)✅ The science behind whole-fruit cranberry supplements vs. extracts✅ Why Pacran is not only effective but also more sustainable and environmentally friendly✅ How both women and men can benefit from daily cranberry supplementation for urinary tract health✅ Introduction to AloeCran — NatureCity’s sugar-free drink mix with 500mg of Pacran + aloe vera and prebiotic fiberRecurring urinary tract problems can be disruptive and painful. This episode explains why the whole cranberry approach may be your best bet for long-term support — if you use a science backed ingredient.Want to Try Pacran for Yourself?Check out AloeCran by NatureCity – packed with clinically-researched 500mg of Pacran + gut-friendly ingredients:Visit: https://www.naturecity.com

  40. 96

    Best Curcumin Supplement? How BCM-95 Can Help You

    To get the most from your curcumin supplement, make sure it’s made with BCM-95.  It also contains turmeric essential oil, which naturally enhances the absorption and bioavailability of curcumin by up to 7x (BCM-95 is also superior to curcumin with black pepper extract).  Plus, BCM-95 is backed by over 90 published scientific studies and research papers.In this episode of the NatureCity Podcast, we reveal why curcumin is so valuable to your health, and some of the specific benefits you can experience with BCM-95 including for joint discomfort and mobility, mood and brain health, immune system function and more.We’ve featured BCM-95 in TrueCurcumin for over 16 years, tune in to hear why!What You’ll Learn in This Episode:✔️ The challenge with curcumin as a supplement ✔️ How BCM-95 curcumin boosts bioavailability up to 7x higher than regular curcumin✔️ The role of curcumin in supporting a healthy inflammation response, improving joint health, mood and supporting overall immune function✔️ The truth about black pepper extract vs. BCM-95 curcumin—which one is better?✔️ How to track your joint health progress with simple tests✔️ Why free curcumin levels in the blood is the measure of bioavailabilityBCM-95 has been used in TrueCurcumin for over 16 years, with many happy users. If you’re looking to support your joints, improve mobility, boost cognitive function, and promote long-term health, this episode is for you!📌 Try TrueCurcumin with BCM-95: Visit NatureCity.com📌 Subscribe for future episodes & expert health insights!👉 Watch Part 1 here.

  41. 95

    Best Curcumin Supplement? Why BCM-95 Is the Top Choice

    Curcumin is one of the most powerful natural compounds, known for its ability to support a healthy inflammation response, promote joint, brain and immune system health, and provide antioxidant benefits. But with so many curcumin supplement ingredients claiming to be the best, how do you choose the right one? In this episode of the NatureCity Podcast, host Carl Pradelli breaks down the differences between curcumin and turmeric, explains why curcumin absorption and bioavailability is a challenge, and reveals why BCM-95 is the premium source for curcumin supplements.What You’ll Learn in This Episode:✅ Curcumin vs. Turmeric – What’s the difference?✅ Why absorption and bioavailability matter when choosing a curcumin supplement✅ How traditional curcumin supplements fail to deliver effective results✅ A concern with black pepper extract in curcumin supplements✅ Why BCM-95 is superior for maximum absorption (700% better!)✅ How BCM-95’s patented formula uses turmeric’s essential oil for better resultsBCM-95 has been the subject of 90+ published research studies and is known for its high potency and purity. Unlike other curcumin products that rely on outside additives or black pepper extracts, BCM-95 uses a 100% natural turmeric-based approach to ensure better bioavailability, safety and effectiveness.Why This Matters for Your HealthCurcumin isn’t just for joint health—it plays a vital role in supporting heart health, cognitive function, immune system strength, and overall wellness. However, regular curcumin supplements don’t absorb well in the body, meaning you’d have to take huge doses daily to get the full benefits. That’s why choosing the right curcumin supplement is crucial for optimal results.Want to Learn More?📌 Check out our TrueCurcumin product page: NatureCity.com📌 Subscribe for future episodes & expert health insights!

  42. 94

    Suntheanine Review: L-Theanine for Stress, Sleep, and Cognitive Performance

    Welcome back to the NatureCity Podcast! Today, we're picking up where we left off with part two of our deep dive into L-Theanine—one of the best natural ways to help your mind relax, so you can focus better in the daytime, or sleep better at night.If you missed part one, we talked about how L-Theanine helps stimulate alpha brain waves, helping your mind reach a calmer, yet alert state. In this episode, we’re discuss some of the research-backed benefits of Suntheanine, the premier form of L-Theanine. We review its benefits for mental clarity and focus, stress support, and sleep.  Last, we share why we use Suntheanine in our TrueZs formula alongside two other powerful natural ingredients that we believe complement L-theanine. If you're looking for a simple, science-backed way to stay sharp and cope better with stress during the day, or fall asleep faster and sleep better at night, you won’t want to miss this one!What You’ll Learn in This Episode:✔️ How L-Theanine supports cognitive performance and stress relief ✔️ The best dosage for optimal results (200mg of Suntheanine) ✔️ How Suntheanine helps promote relaxation without drowsiness ✔️ Why L-Theanine can enhance focus, reaction time and accuracy in everyday tasks ✔️ The role of L-Theanine in better sleep and reducing nighttime disturbances ✔️ Why TrueZs combines Suntheanine with Ashwagandha and Saffron for the ultimate sleep supportHelpful Links & Resources:👉 Watch Part 1 here👉 TrueZs Sleep Support Formula: here👉 More on Suntheanine Research: here

  43. 93

    L-theanine: Why All the Hype? Part 1

    Looking for a natural way to relax your mind so you can focus and sleep better? 🌿 In this episode of the NatureCity Podcast, host Carl Pradelli discusses the rising popularity of L-Theanine, an amino acid known for its calming properties. It’s one of the key nutrients in green tea, and when taken as a supplement it helps to promote alpha brain wave activity, which helps put the mind in a more relaxed and alert state.  It can be used for stress support and mental clarity during the day, and help you fall asleep faster and sleep better at night. Tune in to discover the form of L-Theanine that’s head and shoulders above the rest, and most likely to give you the best bang for your supplement buck!What You’ll Learn in This Episode:✔️ What is L-Theanine? Natural sources like green tea & mushrooms✔️ L-Theanine benefits: Stress support, improved focus & better sleep✔️ How L-Theanine works: Enhancing alpha brain wave & GABA production✔️ Why Suntheanine® is the best L-Theanine supplement (backed by hundreds of research studies!)✔️ How to take L-Theanine for best results & what to avoidL-Theanine is unique because it can be taken during the day for focus and better cognitive performance, or at night to support restful sleep. It’s important to choose a supplement made with a high-quality L-theanine, like Suntheanine. We also reveal how to maximize its benefits while avoiding common mistakes.Stay tuned for Part 2 next week, where we’ll discuss the key benefits from scientific research with Suntheanine, the premier form of L-Theanine, and how we incorporate it into NatureCity’s premium supplement line.🔥 Want to try a premium L-Theanine supplement? Visit NatureCity.com for more information!

  44. 92

    Aloe Vera Drinks EXPOSED: Not the Health Drink You Thought!

    Have you tried those Aloe vera drinks sold in stores? Sounds like a great way to get the health benefits of the Aloe vera plant, right?You might be surprised to learn that many of these Aloe vera drinks are packed with added sugar, neutralizing any potential health benefits.In this episode, Carl Pradelli, CEO of NatureCity, breaks down why many of these drinks are actually just sugar water with a dash of aloe vera— and how this sugar likely offsets the digestion, skin and metabolic health properties of Aloe vera.Better, you’ll hear what you should be drinking instead!  Tune if you’re paying closer attention to nutrition labels and looking for drinks with low sugar or natural sweeteners.What You'll Learn in This Episode:✅ The truth about many Aloe vera drinks and their high sugar content✅ How excess sugar impacts gut health, digestion, and blood sugar metabolism✅ The real benefits of Aloe vera for digestive health, skin, and metabolic health✅ Sugar-free Aloe vera drinks are a much better option – and can still taste good✅ How AloeCran combines organic aloe vera, dietary fiber, and cranberry for a healthier alternativeInstead of consuming high-sugar aloe drinks, NatureCity’s AloeCran drink mix is a sugar-free blend of organic Aloe vera, dietary fiber, and whole cranberry powder—designed to support digestive health, urinary tract function, and metabolic wellness.  It’s delicious and nutritious!👉 Try AloeCran today! Available at NatureCity.com💬 Have you tried Aloe vera drinks? Have you checked the sugar content? Let us know!

  45. 91

    Solnul Resistant Starch: The Gut & Metabolic Health Connection

    Can a simple fiber from potatoes help transform your metabolic health? In this episode of the NatureCity Podcast, CEO and co-founder Carl Pradelli dives into groundbreaking research on Solnul, a powerful resistant starch dietary fiber derived from Canadian potatoes.  This is Part 2 of our Solnul series, where we break down the latest scientific findings showing how the benefits of just 3.5 grams of Solnul per day can go “beyond the gut”.  In particular, you’ll discover how Solnul can support metabolic function (key for weight management, blood sugar metabolism, and heart health), help protect collagen (which may help skin appearance), as well as provide prebiotic activity in the gut, support healthy intestinal barrier function and healthy bowel movements.  Missed Part 1? Watch it here: https://bit.ly/40EeE4b What You’ll Learn from This Episode: ✅ How Solnul helps regulate free fatty acids—an early marker of metabolic dysfunction✅ The link between friendly gut bacteria (Akkermansia) and improved metabolic health✅ How Solnul may protect healthy collagen from degrading✅ The role of Solnul in supporting a healthy gut barrier (helping protect against “leaky gut”)✅ How Solnul may help promote regular and healthy bowel movements✅ Why Solnul is sustainable & eco-friendly, utilizing upcycled resistant potato starch Want to try Solnul for yourself? It’s a key ingredient in TrueDYB Digest Your Best, our premium digestive support formula. Learn more at NatureCity.com

  46. 90

    Solnul Fiber Supports Metabolic Health

    In this episode,  you’ll discover a new benefit of the powerful prebiotic fiber called Solnul, which comes from potatoes. A recent study indicates Solnul can help improve metabolic health – which is key for weight management, blood sugar and heart health.Even more fascinating, Solnul was found to have a positive impact on the earliest indicator of declining metabolic function.  Join Carl Pradelli on the NatureCity Podcast as he shares the details into this groundbreaking research that suggests Solnul may even benefit healthy adults who aren’t otherwise showing a change in metabolic health and help support your health goals.What You’ll Learn in This Episode:Understand why resistant starch, which works as a dietary fiber in the body, is different from regular starch.Why aren’t we getting nearly as much resistant starch as our ancestors?The importance of healthy metabolic function for weight management and burning fat.Why free fatty acid levels are believed to be the earliest indicator of declining metabolic function.How Solnul improved this marker of metabolic function in just 28 days, even in healthy adults.Mentioned in This Episode:TrueDYB: NatureCity’s digestion super formula featuring Solnul, inulin, and PreforPro. Find it exclusively at NatureCity.com.

  47. 89

    How to Choose the Best Prebiotic Supplement for Gut Health

    Welcome to this week’s episode of the NatureCity Podcast! Hosted by Carl Pradelli, CEO and co-founder of NatureCity, this episode explores what to seek in probiotic ingredients and find the right blend of nutrients - usually one is not enough to optimize gut health and wellness.  A prebiotic is a non-digestible ingredient that stimulates the growth of good probiotic bacteria, helping them flourish and improve health – but not all prebiotics are created equal – some can cause unwanted effects.In this episode, Carl breaks down:What prebiotics are and how they differ from probiotics.The three key criteria for choosing the right prebiotic blend.How a new generation of prebiotics, like PreforPro, can help take gut health to the next level..The need for prebiotic support to promote Akkermansia, Lactobacillus, and Bifidobacterium microorganisms for gut and metabolic health.The unique prebiotic and digestive benefits of NatureCity’s digestion super formula, TrueDYB.If you’ve ever wondered what to look for in a prebiotic supplement or how prebiotics can improve your gut health, this episode is for you.Be sure to listen until the end, as Carl reveals how TrueDYB combines prebiotics, probiotics, postbiotics and herbal support to create a truly comprehensive digestive health supplement.Mentioned in This Episode:TrueDYB: NatureCity’s digestion super formula featuring Solnul, inulin, and PreforPro. Find it exclusively at NatureCity.com.

  48. 88

    Exploring Shoden® Ashwagandha for Stress, Sleep, and Testosterone

    In this episode of the NatureCity Podcast, Carl Pradelli reveals the latest scientific findings with Shoden®, a high-potency ashwagandha extract, which is quickly becoming known for its wide-ranging health benefits.Carl describes how the research found that Shoden® can help the body cope with stress, support healthy cortisol levels, improve sleep quality, and for men, promote increased testosterone levels. He explains what makes Shoden® unique compared to other ashwagandha extracts, and why its effectiveness at smaller doses sets it apart in the supplement industry.Carl also discusses how Shoden® is featured in NatureCity’s TrueZs formula, which combines L-theanine, saffron, and Shoden® ashwagandha into a convenient, flexible product for stress and sleep support.Whether you're interested in improving your sleep, managing stress, or boosting testosterone levels, this episode offers actionable insights and helpful guidance._______Follow NatureCity on Social MediaInstagram: https://www.instagram.com/NatureCitySupplements/Facebook: https://www.facebook.com/naturecitysupplements

  49. 87

    Astaxanthin: The Rising Star for Youthful Looking Skin

    In this week’s episode of the NatureCity Podcast, host and co-founder Carl Pradelli reveals the many skin health benefits of supplementing with astaxanthin – one of the most powerful antioxidants in nature.Carl explores the science behind how astaxanthin can help skin look more youthful, promote skin hydration and smoother skin, reduce the appearance of wrinkles and age spots, and improve skin elasticity and texture.Among the many ways astaxanhin works is by supporting collagen, hyaluronic acid and elastin formation and protecting the skin from oxidative stress.The 6mg of AstaReal astaxantin found in every TrueAsta soft gel is an ideal way to capture the benefits of astaxanthin in a supplement._______Follow NatureCity on Social MediaInstagram: https://www.instagram.com/NatureCitySupplements/Facebook: https://www.facebook.com/naturecitysupplements

  50. 86

    Low Calcium and Magnesium May Hurt Cognitive Function

    In this episode of the NatureCity podcast, Carl Pradelli discusses the results of a recent study involving two essential minerals - calcium and magnesium. You may not associate calcium and magnesium with brain health, but this study underscores why we need to ensure our bodies get adequate amounts of these minerals daily to help our mind stay sharp. The study, conducted with over 1,200 adults aged 60 and older, found that low blood serum levels of calcium and magnesium were associated with poorer cognitive function. This research adds to the growing evidence that maintaining healthy levels of these minerals is important for brain health, especially as we age. You’ll also hear about the best form of these minerals to take in a supplement to help bridge dietary gaps. Visit Nature City for more information on these supplements or reach out with any questions.Thank you for tuning in!

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ABOUT THIS SHOW

The Nature City Podcast dives into the world of supplements and nutrition to help you make the best decision for your health and lifestyle needs. Hosted by CEO and Founder Carl Pradelli, The Nature City Podcast is your go-to podcast for all things supplements, nutrition, and much more.To learn more about Nature City and our work, visit https://www.naturecity.com/You can also follow us on Youtube to watch the latest episodes, of the Nature City Podcast

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Nature City

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