#26 Your mitochondria run the engine. MOTS-C keep it firing. episode artwork

EPISODE · Mar 15, 2026 · 15 MIN

#26 Your mitochondria run the engine. MOTS-C keep it firing.

from Peptalk: Peptides Unpacked · host Dr. Kylie Burton & Jessica Briecke

MOTS-C is a peptide your mitochondria actually produce — a native signal that tells your cells to pull in glucose, burn fat, and build new energy infrastructure. When that signal fades with age, the results are familiar: stubborn weight, sluggish energy, brain fog, and workouts that stop paying off.This episode breaks down exactly how MOTS-C flips your body's master energy switch, AMPK, in plain English — no biology degree required. We cover who benefits most, from blood sugar swings and weight plateaus to athletic performance and longevity, and why women in menopause are finding it especially powerful without touching hormones.We also answer the question everyone's thinking: are peptides even natural? Spoiler — your body's been making them all along.By the end you'll know:Why mitochondrial decline tracks directly with aging and metabolismHow to pair MOTS-C with training, nutrition, and sleep for compounding resultsWhich labs and performance cues to track progressThis isn't a miracle. It's a map — rooted in how your cells already work.MOTS-C just became available this month — it's next for Jess and I.  Get it on your list. Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.comReady to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop. Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com. Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.You have the science. You have the tools. Now it's time to take the next step.This is PepTalk: Peptides Unpacked—science made simple, re...

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MOTS-C is a peptide your mitochondria actually produce — a native signal that tells your cells to pull in glucose, burn fat, and build new energy infrastructure. When that signal fades with age, the results are familiar: stubborn weight, sluggish energy, brain fog, and workouts that stop paying off. This episode breaks down exactly how MOTS-C flips your body's master energy switch, AMPK, in plain English — no biology degree required. We cover who benefits most, from blood sugar swings and wei...

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#26 Your mitochondria run the engine. MOTS-C keep it firing.

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This episode was published on March 15, 2026.

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