#44 The Ripped Guy at the Gym Has a Secret — Steve Smith on Peptides and Beating the Odds episode artwork

EPISODE · Jun 14, 2026 · 59 MIN

#44 The Ripped Guy at the Gym Has a Secret — Steve Smith on Peptides and Beating the Odds

from Peptalk: Peptides Unpacked · host Dr. Kylie Burton & Jessica Briecke

What does it look like to spend your entire life fighting a body that attacks itself — and win?Steve was diagnosed with dermatomyositis at 11 years old. It's a rare autoimmune disease where the immune system turns on its own muscle fibers, stealing strength, movement, and for a kid who lived for sports, identity. He couldn't lift a half-gallon of milk. At a young age, he was put on a cocktail of medications that caused him to balloon in weight, and then a routine school vaccination triggered a relapse that derailed his entire junior year of high school. By the time he was a teenager, he had already survived a ruptured appendix, a near-fatal surgery, and years of being dismissed, misdiagnosed, and judged for a body that was doing things nobody could help resolve.Now at 46, he's the guy people accuse of being on steroids.Steve didn't get there with a magic protocol or a shortcut. He got there by making health-conscious decisions starting at age 11, never touching soda once in 35 years, studying the science of movement rather than chasing ego lifts — and four years ago, discovering peptides.In this episode, Steve sits down with Jess and Dr. Kylie to talk about what peptides actually did for someone who had every reason to give up on his body, and why he believes they're the great equalizer for anyone who's been told their best days are behind them.What we cover in this episode:What dermatomyositis actually is — and why it took four doctors and a Yale-trained specialist to finally diagnose itHow an MMR vaccine triggered a relapse that changed the course of his teenage yearsThe BPC-157 + TB-500 combo: how he went from a hamstring tear to running on a treadmill in two and a half weeksWhy he lifts for science, not ego — and what that philosophy has saved him fromHis honest take on Retatrutide: why it works for some people and why it's not for himMOTS-C: the peptide he's researching next to compensate for his one non-negotiable bad habit — sleeping only four and a half hours a nightMelanotan II: the air fryer story (you'll understand when you hear it)Why he believes peptides are the opposition to an industry that profits from people staying sickSteve's current stack:BPC-157/TB-500 — maintenance dose, every 72 hours (non-negotiable)GHK-Cu (copper peptide) — adding back in now that sourcing costs have come downTesamorelin + Sermorelin — for GH support and muscle compositionMelanotan II — situationalMOTS-C — next on deckWhat's next for you? Want to connect more with the hosts? We'd love it! Connect with Jess at B2BwithJess.com/peptides or on Instagram @jessb.talkshealth. Grab your Blood Work & Peptides Mini Guide for free at drkylieburton.com. Ready to explore peptide therapy for yourself? Visit the company we recommend for pharmaceutical peptides and receive all the one-on-one support that comes included at drkylieburton.comWant to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.comLegal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.You have the science. You have the tools. Now it's time to take the next step.This is PepTalk: Peptides Unpacked—science made simple, results made real.

What does it look like to spend your entire life fighting a body that attacks itself — and win? Steve was diagnosed with dermatomyositis at 11 years old. It's a rare autoimmune disease where the immune system turns on its own muscle fibers, stealing strength, movement, and for a kid who lived for sports, identity. He couldn't lift a half-gallon of milk. At a young age, he was put on a cocktail of medications that caused him to balloon in weight, and then a routine school vaccination tri...

NOW PLAYING

#44 The Ripped Guy at the Gym Has a Secret — Steve Smith on Peptides and Beating the Odds

0:00 59:19

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

Circana Unpacked Circana Circana Unpacked delves into the data to reveal consumer, shopper, and other insights that fuel market changes and growth for those in the CPG, retail, health care and media industries. Join Circana thought leaders, industry partners and guests to learn how opportunities, trends and market disruptions will impact your business. Out of the Box Judaism Podcast Out of the Box Judaism Podcast by Esther Goldenberg This podcast is for people who are interested in Out-of-the-Box Judaism -- whether Jewish or not.What does out of the box mean?Out-of-the-Box can mean… thinking outside the box. Many people have an impression or idea of what it means to be Jewish or what you have to do to be Jewish or what you have to believe to be Jewish. Out-of-the-Box can mean thinking outside the box of preconceived notions and creating the Jewish experience that is right for you.Out-of-the-Box can mean… being outside of the synagogue. Many people feel that joining or going to a synagogue doesn’t fulfill their desire for a deeper connection. Out-of-the-Box can mean finding and creating meaningful spiritual experiences on your own, with your family, or with a community that is not based in a synagogue.Out-of-the-Box can mean… unpacking your heritage. If you or someone in your family is Jewish, you have a box of hand-me-downs and treasures waiting to be unpacked. Out-of-the-Box can mean examining those contents, Politics Unpacked Times Radio Hugo Rifkind unpacks the the politics of the day - and the stuff that's even more important - with the brightest brains from the Times and Sunday Times.You can listen to Hugo on DAB, smart speaker or app 10am-1pm Monday to Friday. If you like what you hear, then read more at http://www.thetimes.com/ Hosted on Acast. See acast.com/privacy for more information. The Human Upgrade: Biohacking for Longevity & Performance Dave Asprey For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger

Frequently Asked Questions

How long is this episode of Peptalk: Peptides Unpacked?

This episode is 59 minutes long.

When was this Peptalk: Peptides Unpacked episode published?

This episode was published on June 14, 2026.

What is this episode about?

What does it look like to spend your entire life fighting a body that attacks itself — and win?Steve was diagnosed with dermatomyositis at 11 years old. It's a rare autoimmune disease where the immune system turns on its own muscle fibers, stealing...

Can I download this Peptalk: Peptides Unpacked episode?

Yes, you can download this episode by clicking the download button on the episode player, or subscribe to the podcast in your preferred podcast app for automatic downloads.
URL copied to clipboard!