Can Antibiotics Ever Beat Evolution?

What this episode covers

Antibiotics made modern medicine possible, but every prescription runs a global selection experiment for resistant bacteria. This episode explores the evolutionary arms race between humans and microbes — from horizontal gene transfer and the hidden resistome in soil bacteria to the market failures that have dried up the antibiotic pipeline. We examine NDM-1, the enzyme that collapsed an entire drug class, and mcr-1, the colistin resistance gene that jumped from pig farms to human pathogens. Plus: the PASTEUR Act's subscription model for drug development and LpxC inhibitors that could turn resistance into a self-defeating strategy.

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How long is this episode of My Weird Prompts?

This episode is 30 minutes long.

When was this My Weird Prompts episode published?

This episode was published on June 8, 2026.

What is this episode about?

Antibiotics made modern medicine possible, but every prescription runs a global selection experiment for resistant bacteria. This episode explores the evolutionary arms race between humans and microbes — from horizontal gene transfer and the hidden...

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