PODCAST · health
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
by Karen Martel: Certified Hormone Specialist
The Hormone Solution is a top-ranked women's health podcast focused on perimenopause, menopause, hormone replacement therapy (HRT), weight gain, metabolism, thyroid health, and midlife transformation.Hosted by Certified Hormone Specialist Karen Martel, this show helps women in their 40s and 50s understand what's really happening with their hormones — and what to do about it.If you're struggling with perimenopause symptoms, menopause weight gain, estrogen dominance, low progesterone, testosterone decline, brain fog, poor sleep, thyroid dysfunction, or metabolic slowdown, this podcast breaks it down in a clear, practical, no-nonsense way.Each episode features:• Evidence-based hormone education• Expert interviews• Real-world HRT guidance• Midlife weight loss strategies• Thyroid and metabolic health insightsWith over 2.5 million downloads and ranked in the Top 30 on iTunes, The Hormone Solution is trusted by women worldwide who want real answers about bioidentical hormones, menopa
Episodes
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Quick Hits: Breathwork for Women: Igniting Inner Empowerment with Kyla Erlandson
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode. Listen to the full…
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Tired, Wired, Puffy, and Foggy? Minerals May Be the Missing Piece with Caroline Alan
You are taking the supplements. Drinking the water. Maybe you are even on HRT. And yet you still feel tired, puffy, anxious, inflamed, constipated, foggy, wired at night, and completely drained during the day. What if one of the missing pieces is far more basic than another hormone, peptide, or...
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Quick Hits: Reversing Hashimoto's Disease: Insights from Dr. Anshul Gupta
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode. Listen to the full…
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HRT & GLP-1 Q&A: Progesterone Problems, Hair Loss, Weight Gain, and More
What do you do when you finally start HRT and instead of feeling amazing, you feel exhausted, puffy, bloated, or like something is just not right? Or you start a GLP-1, lose weight, and suddenly your hair starts falling out? Today's episode is another listener Q&A, and we are getting into the...
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Quick Hits: The No BS Guide: Ditching Excuses and Taking Charge of Your Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode. Listen to the full…
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GLP-1s and Menopause: What Every Woman Over 40 Needs to Know
You cannot open your phone anymore without hearing about Ozempic, Wegovy, Mounjaro, Zepbound, retatrutide, and before-and-after transformations. One person says GLP-1s are the greatest thing ever. Another says they are going to destroy your health. As usual, the truth is somewhere in the middle.…
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Estrogen Dominance Explained: What Every Woman on HRT Needs to Know
If you are taking HRT, it is not enough to only ask how much estrogen you are using. You also have to ask a second question: how well is your body actually processing and clearing that estrogen? In this episode, I sit down with David Roberts and John Gilday from Mara Labs to unpack estrogen...
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Your Body Isn't Broken: Why Doing More Can Make Midlife Worse with Debbie Potts
Have you ever felt like you are doing everything right and your body is just not cooperating? You are eating well, exercising, tracking your protein, fasting, taking supplements, getting your steps in, and still gaining weight, feeling exhausted, sleeping poorly, and wondering why the strategies...
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Part 1 The Midlife Stress Crash: Why You Feel Wired, Tired, Anxious & Done
If you are waking up between 2:00 and 4:00 AM, lying there wide awake with your heart beating a little too fast and your mind solving every problem in your life, this episode is for you. Because this is not just about bad sleep. It is about what happens when the hormonal, adrenal, and nervous...
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Quick Hits: The Great Menopause Myth: The Truth on Mastering Midlife Hormonal Mayhem
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode Listen to the full…
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JJ Virgin: The Untold Story of Aging, Weight Gain, HRT, Peptides, Facelifts, and Muscle
This conversation is not just about menopause symptoms. It is about what it actually feels like to live inside a changing female body in midlife. The grief, the confusion, the vanity, the softness, the strength, the reinvention. All of it. In this episode, I sit down with fitness hall of famer…
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Quick Hits: GLP-1s (Ozempic & Mounjaro) Masterclass: Busting Myths, Mastering Micro Dosing, Retaining Muscle and Unlocking Benefits Beyond Weight Loss with Dr. Gus Vickery
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode here. How can GLP-1s like...
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The Brain Fog Fix No One Is Talking About: Nicotine, Methylene Blue and the Midlife Brain with Dr. Scott Scherr
We talk a lot about hormones in midlife, hot flashes, weight gain, sleep issues, low libido. But one of the biggest complaints I hear from women is actually about their brain. The brain fog. The anxiety that comes out of nowhere. The flat motivation. The unpredictable sleep. The feeling that you...
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Quick Hits: The Histamine Connection to Estrogen Dominance, Acid Reflux, Insomnia, & MORE with Joanne Kennedy
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode on iTunes Joanne Kennedy…
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The Problem With 'I Did Menopause Naturally, So Should You'
Menopause is finally having a moment, but with more conversation has come a whole lot more confusion. In this solo episode, Karen breaks down the three camps she sees in the menopause conversation: women who are informed and empowered, women who shame or dismiss HRT, and the large group of women...
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Quick Hits: The Great Estrogen Debate with Dr. Felice Gersh, Dr. Daved Rosensweet, Dr. Lindsey Berkson, Dr. Julie Taguchi & Karen Martel
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode: https://karenmartel.com/blogs/podcast/the-great-estrogen-debate iTunes:...
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The Thyroid Myths That Keep Women Tired, Fat, and Dismissed with Dr. Amie Hornaman
If you have ever been told your thyroid is "normal" while you are exhausted, gaining weight, losing hair, constipated, freezing cold, and barely making it through the day, this episode is going to hit a nerve. Because the truth is, thyroid care is still failing women in a big way. Too many…
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Quick Hits: Are Toxins Hijacking Your Hormones? What Every Woman Needs to Know with Dr. Paul Anderson
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Discover innovative therapies like low-dose…
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Meno Besties Unfiltered: Bones, Hormones & Hot Hockey Players
What happens when three menopause podcasters sit down together with zero intention of staying surface level? You get a smart, honest, hilarious, and deeply validating conversation about some of the biggest midlife topics women are trying to figure out right now. In this roundtable episode, we get...
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The Menopause Gut: What Hormone Loss Is Really Doing to Digestion, Inflammation, and Weight with Cynthia Thurlow
In this episode, I sit down with Cynthia Thurlow, nurse practitioner, TEDx speaker, and author of The Menopause Gut, to unpack what is really happening inside the body during this transition. We get into why so many women suddenly feel bloated, constipated, reactive to foods, inflamed, and...
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Quick Hits: Metals & Menopause: The Impact of Heavy Metals on Your Sex Hormones, Thyroid, and Energy with Dr. Chris Shade
Join our FREE upcoming masterclass: Why Midlife Weight Gain Won't Budge A smarter way to use GLP-1s in midlife without wrecking muscle or metabolism When: April 30th 11 am PST Register here: https://coaching.karenmartel.com/glp1-masterclass Welcome to Quick Hits — where we bring you the most...
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We've Used GLP-1s for 3 Years: What Worked, What Backfired, and What Women Need to Know
Three years ago, GLP-1 peptides were barely being talked about in the midlife women's health space. Since then, Jessica and I have personally used them, experimented with different approaches, and helped over a thousand women inside our peptide program navigate what works, what backfires, and…
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The Real Reason Your Menopause Belly Shows Up Even When You're Doing Everything Right with Siobhan Mitchell
Join our FREE upcoming masterclass: Why Midlife Weight Gain Won't Budge A smarter way to use GLP-1s in midlife without wrecking muscle or metabolism When: April 30th 11 am PST Register here: https://coaching.karenmartel.com/glp1-masterclass There comes a point for so many women in their late 30s...
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Part 2: What Midlife Women Need to Know About Testosterone & Steroids with Victoria Felkar
In this second of two parts, I sit down with Victoria Felkar again to unpack the complicated, often glamorized world of androgens, testosterone therapy, and anabolic steroids for women. Are these hormones empowering tools—or ticking time bombs? How do you know the difference? We dive into what's...
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Quick Hits: Cracking the Genetic Code: Unlocking the Link Between Genetics, Hormones, Detox, Diets, Mood, and More
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode iTunes Have you ever...
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Part 1: Women Have Been Lied To About Testosterone with Victoria Felkar
In this episode, I'm joined by the brilliant Victoria Felkar, and we go where most conversations in women's health simply don't: anabolic steroids. Why has this topic been so misunderstood—and even feared—by women, especially in midlife? Are we lumping very different hormones into one "scary"...
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Quick Hits: The Hidden Role of Melatonin in Hormones, Aging, and Sleep with Deanna Minich
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full peptide here:...
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The Menopause Metabolic Storm: Why Estrogen Loss Makes Weight Gain So Hard to Escape
Are you ready for a true masterclass? In this solo episode, I'm diving deep into estrogen and metabolic health—and trust me, this one challenged even me. Is estrogen really making you gain weight, or is the real problem what happens when it drops? If you've hit your 40s or 50s and suddenly…
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Quick Hits: From Breast Cancer to Bone Health: The Uncharted Territory of HRT & Chronic Diseases in Menopause with Dr. Elizabeth Yurth
Listen to the full peptide here: https://karenmartel.com/blogs/podcast/from-breast-cancer-to-bone-health-the-uncharted-territory-of-hrt-chronic-diseases-in-menopause-with-dr-elizabeth-yurth Download on Apple and on your favorite podcast platform....
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The Mental Health Crisis No One Is Linking to Hormones with Dr. Louise Newson
Why are so many of us blindsided by anxiety, depression, rage, or even suicidal thoughts in midlife? And why are hormones so often left out of the conversation? I'm joined by the incredible Dr. Louise Newson, a UK-based GP and menopause specialist, to talk about something far too many women...
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Copper Peptides & Exosomes: The Skin Regeneration Breakthrough for Women Over 40
Have you looked in the mirror lately and wondered, when did my skin change like this? In this episode, I'm joined by Debbi Barber (founder of Vitali Regenerative Skincare) and Dr. Jordan Plews (a stem cell scientist and co-founder of Xytogen Biotech) to unpack what's really happening to our skin…
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The Hormone–Histamine Connection Doctors Aren't Talking About
In this Hormone Hotline episode, I'm answering a powerful question about estrogen HRT, histamine intolerance, and mast cell activation during perimenopause and long COVID. Why do histamine flares explode when hormones start shifting? Is estrogen really the villain—or is something deeper driving…
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Quick Hits: The New Science of Midlife Fat Gain + The Top Strategies for Menopause Weight Loss with Dr. Bill Campbell
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. Listen to the full episode here:...
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The Gut–Vagina–Brain Connection: The Hidden Reason Women Lose Libido After 40 with Dr. Betsy Greenleaf
Vaginal dryness, recurrent infections, low libido...why are we told this is "just hormones" and something we have to tolerate? In this episode, I sit down with Dr. Betsy Greenleaf, founder of the International Pause Institute, and we unpack what's really happening down there during perimenopause...
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Quick Hits: The Women's Hormone Masterclass: A Deep Dive Into Testosterone, Dutasteride, SHBG, & Menopause Weight Gain with Dr. Kyle Gillett
Listen to the full episode Download the full episode on Apple or on your favorite podcast platforms. In this quick hits I sit down with Dr. Gillett, to exam the complex world of women's hormones today. We'll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their...
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Am I in Perimenopause? How to Tell What Phase You're In
If you had told me at 40 that perimenopause would turn my world upside down, I would've laughed. As a nutritionist specializing in women's hormones, I thought I had it handled. So why did I gain 15 pounds, lose my sleep, and feel like a stranger in my own body? In this episode, I'm sharing what I...
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Quick Hits: Navy SEAL Health Hacks: Sleep, Peptides, Psychedelics, Brain Health, and Hormones with Dr. Kirk Parsley
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today's clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. In this quick hits episode you will hear a clip from...
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The Peptide Revolution: GLP-1s — What Works, What's Hype, What's Risky with Jay Campbell
Jay Campbell—five-time international bestselling author, founder of BioLongevity Labs, and one of the original voices in the peptide world—is here to unpack what's really going on behind the GLP-1 explosion. Are these drugs miracle tools or misunderstood villains? And why are so many smart people...
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Menopause Ages You 9–20 Years… Unless You Do This with Nikolina Lauc
In this episode, I sit down with Nikolina Lauc, CEO and Co-Founder of GlycanAge, and we dive into a questions that should stop every midlife woman in her tracks: is menopause actually accelerating your biological aging? What if the shift from perimenopause to menopause could age you up to nine...
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Estrogen Dominance… or Estrogen Deficiency? Is It Safe to Start Estrogen in Perimenopause?
Welcome to the very first Hormone Hotline episode of The Hormone Solution! I'm getting straight into your real-life questions about estrogen—because why, in 2026, are we still being told we're "estrogen dominant" with rock-bottom levels? If your doctor has warned you against HRT, this episode is...
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From Toe Curling Orgasms to Healthy Poops: Why Oxytocin Is Essential for Midlife Women with Dr. Lindsey Berkson
What if your mood swings, anxiety, sleep issues, or loss of motivation aren't just "getting older?" What role does oxytocin really play in midlife, and why has it been overlooked for so long? In this episode, I'm joined by the brilliant hormone scholar Dr. Lindsey Berkson, and we dive into a part...
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Inflammaging Is Hijacking Your Hormones: The Ancient Reset Women Need in Midlife with Dr. Shivani Gupta
Do you know whether you're Vata, Pitta, or Kapha...and could that explain your stubborn symptoms in midlife? In this episode, I'm joined by my brilliant friend Dr. Shivani Gupta, and we dive into Ayurveda, inflammation, and why your body might be asking for a completely different approach right...
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Why So Many Hormone Providers Get It Wrong (And How to Find One Who Doesn't)
This episode comes straight from my own lived experience of spiraling before doctor's appointments and feeling dismissed when it comes to hormones. I dig into why so many hormone providers get it wrong and what's actually happening behind those rushed, frustrating conversations. Why does…
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Why You're Not Healing: Stress, Insomnia, Weight Gain & the Vagus Nerve with Dr. Navaz Nabib
Have you've tried everything from protocols, to supplements, to experts and the healing still hasn't happened? Why do so many of us stay stuck despite doing "all the right things"? In this episode, I sit down with Dr. Navaz Habib, aka "The Vagus Nerve Doc," to explore what might be missing. What…
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Why Waiting for Menopause Is a Mistake: The Case for Earlier HRT and Replacing Hormones the Right Way
I'm diving into why waiting until menopause to address hormones can be an incredibly costly mistake for so many women. Why are we told to "wait it out" when symptoms often start years earlier? And what's really happening inside our bodies long before our periods stop? I walk through the...
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Why Your Gut Is Sabotaging Your Hormones (and Your Hormones Are Sabotaging Your Gut) with Kiran Krishnan
I'm sitting down with microbiome expert Kiran Krishnan to explore a question I see come up all the time: why do hormones sometimes stop responding the way they used to? But what if the real issue isn't your hormones at all, rather what's happening in your gut? In this episode, we dig into the...
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Goodbye 2025: A Year of Healing, Hard Truths, and Growth
It's time to say goodbye to 2025, so let's get real about a year that looked successful for me on the outside, but sometimes felt like a reckoning on the inside. What happens when your body forces you to slow down? And what do you do when growth starts to cost you your peace? I open up about...
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Part 2 Q&A with Karen: Cortisol Replacement, Optimal Levels, HRT Absorption Issues, Estrogen Detox, BIEST Troches, Perimenopause Confusion & More!
This episode picks up right where part one leaves off as I dive into more of your thoughtful, honest questions in the second-part of this year-end Q&A. What happens when hormone therapy doesn't seem to be working the way you expected? And how do you know if your dose is actually doing what you…
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Q&A with Karen: High Ferritin, Injectable HRT, Breakthrough Bleeding, Optimizing Hormones, Histamine Intolerance and MORE!
I'm wrapping up the year by answering your questions in this first of a two-part Q&A, and we cover a lot of ground. From confusing lab results to hormone dosing debates, I dig into the questions so many of you are quietly wondering about. What does high ferritin really mean? Is it iron—or…
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From Belly Fat to Brain Fog: The Top Peptides, & Hormones Helping Women in Menopause with Dr. Aleksandra Gajer
What's really driving the sudden belly fat, brain fog, and sleep chaos so many women hit in midlife? And why do the usual "eat less, move more" solutions stop working overnight? In this episode featuring Dr. Aleksandra Gajer, we dig into the hormones and peptides that may finally explain why your...
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ABOUT THIS SHOW
The Hormone Solution is a top-ranked women's health podcast focused on perimenopause, menopause, hormone replacement therapy (HRT), weight gain, metabolism, thyroid health, and midlife transformation.Hosted by Certified Hormone Specialist Karen Martel, this show helps women in their 40s and 50s understand what's really happening with their hormones — and what to do about it.If you're struggling with perimenopause symptoms, menopause weight gain, estrogen dominance, low progesterone, testosterone decline, brain fog, poor sleep, thyroid dysfunction, or metabolic slowdown, this podcast breaks it down in a clear, practical, no-nonsense way.Each episode features:• Evidence-based hormone education• Expert interviews• Real-world HRT guidance• Midlife weight loss strategies• Thyroid and metabolic health insightsWith over 2.5 million downloads and ranked in the Top 30 on iTunes, The Hormone Solution is trusted by women worldwide who want real answers about bioidentical hormones, menopa
HOSTED BY
Karen Martel: Certified Hormone Specialist
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