PODCAST · health
The Peptide PhDs Podcast
by MAKE Wellness
The Peptide PhDs — the show where two science geeks with PhDs turn the complex world of peptides into stories you’ll enjoy. Dr. Mark Bartlett sees peptides as the secret language immune cells use to gossip, negotiate, and sometimes throw shade. Dr. Alan Jones looks at muscle as an endocrine powerhouse, flexing out a vocabulary of peptides that strengthen body and brain.Each week we break down new discoveries from the lab, chat with guest experts, and unleash our cringy dad jokes. We hope it's a fun way to understand how these tiny molecules have a huge impact on health and wellness.
Episodes
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Don't Sleep on Muscle - A Conversation with Crystal
Remember when fitness was all about endless cardio, tiny pink dumbbells, and avoiding muscles at all costs? Yeah, we might owe our bodies an apology. In this episode of The Peptide PhDs, Dr. Mark welcomes his wife, Crystal, for a conversation that connects emerging peptide science with the…
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The Adventures of One Tiny Peptide
A tiny peptide. Stomach acid. Digestive enzymes. A whole lot of molecular scissors. So, what actually happens during digestion? In this episode of The Peptide PhDs, Dr. Mark and Dr. Jones tackle one of the biggest questions surrounding natural peptides: Can they actually survive digestion? With a...
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This Time, It's All About Muscle
Muscle has apparently been running a group chat with the rest of your body this entire time, you might have just had it on mute. This week, The Peptide PhDs dive into the surprisingly chatty world of muscle. Active muscle can release hundreds of chemical messengers called myokines, communicating...
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When Peptides Attack
Peptides usually get talked about for things like sleep, muscle, skin and metabolism. This week? Rattlesnakes and deadly spiders enter the chat. The Peptide PhDs explore the surprisingly wild side of peptide science, from venom and nature-made defense systems to the discoveries that have helped...
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Beauty Is More Than Skin Deep - Part 3
You did it. You are about to know about everything beauty! This episode of The Peptide PhDs breaks down how collagen gives skin structure, elastin provides bounce, hyaluronic acid helps with hydration, and peptides act like tiny text messages telling skin cells what to do. They also cover what…
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Beauty Is More Than Skin Deep - Part 2
The Peptide PhDs are back for round 2 of their deep dive into beauty. Apparently, skin has a language, but it is not fluent in expensive moisturizer. In this episode, the Peptide PhDs explore how collagen fragments and bioactive peptides act as biological messages, telling the skin’s fibroblasts...
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Beauty Is More Than Skin Deep - Part 1
What if we told you, in this episode, Dr. Jones and Dr. Mark are talking about tanning and new clothes? Don't worry, our PhDs aren't out on the town going for a new look. No, in this episode of The Peptide PhDs, they are talking about a different outward appearance: the skin. Our skin is more…
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Maintaining Physical Independence as We Age
What do our founding fathers and peptide signaling have in common? More than you might think. In this special Independence Day episode, Dr. Mark and Dr. Allen dive into myokines, metabolism, muscle, and modern peptide science. Along the way, they explore why muscle is the currency of healthy…
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Get Under the Hood of Protein
Protein is having a moment—and, as usual, social media has made things complicated. Are you eating too little, consuming too much, or just aggressively shaking powder into a bottle and hoping for the best? In this episode, the Peptide PhDs get under the hood of protein to explore what actually...
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Conversations Between Brain and Body
This week, The Peptide PhDs are putting your brain on peptides—and no, this is not another scrambled-egg public service announcement. Dr. Mark Bartlett and Dr. Alan Jones break down how peptides and amino acids help create a communication network between the brain and the rest of the body. From…
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There's More to Your Body Than Just a Scale
After a long hiatus, we're back! Dr. Mark and Dr. Alan dive into body composition—aka why the number on the scale is not the whole story, and sometimes not even the right story. Come unpack the difference between weight loss and improving the ratio of lean muscle to body fat, explaining how…
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The 12 Hallmarks of Aging Part 3: The Final Four
In this episode of Peptide PhDs, Dr. Mark and Dr. Alan wrap up their three-part tour through the 12 hallmarks of aging by tackling the final four: stem cell exhaustion, altered cellular communication, chronic inflammation, and dysbiosis. Translation: the body’s repair crews get tired, the…
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The 12 Hallmarks of Aging Part 2: More Zombie Cells and Removing Loud Cells
In part 2 of our Hallmarks of Aging series, the PeptidePhDs are back on the case — detective hats, zombie cells, muscle talk, and all. This episode dives into five more biological “clues” behind aging. From proteins that stop folding properly to cells thatforget how to take out the trash, the...
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Hallmarks of Aging Part 1 - Aging at the cellular level...and zombie cells?! Oh my!
Ever wonder why we age... at the cellular level? Have you ever heard of "zombie cells"? Well, you should, because they’re currently throwing a party inside your body—and they didn't invite you. This week, Dr. Mark and Dr. Alan kick off a brand-new series breaking down the 12 Hallmarks of…
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Natural Peptides Explained--and where is Dr. Jones?!
Has Dr. Jones been replaced?! With him away in Barcelona, Dr. Mark flies solo—luckily, Crystal is here to keep him honest! This week, we're diving into a major Science News article asking the big questions: Are peptides truly proven health aids, and is the FDA about to open the door regardless?…
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What's really happening when you're low on energy?
The mitochondria is the powerhouse of the cell. Great. Now that we’ve cleared high school biology, let’s talk about why you’re actually exhausted. Most people think "low energy" is just a sleep deficit. Spoiler alert: It’s usually not. In this episode, Dr. Mark Bartlett and Dr. Alan Jones go...
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Body Composition Part Deux
Dr. Mark Bartlett and Dr. Alan Jones are back on the Peptide PhD Podcast to remind us that weight loss is great, but muscle is better. They continue their deep dive into body recomposition and why building and keeping muscle matters way more than just losing weight. In this episode, they break…
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Body Composition Part 1: Don't Trust the Scale
Stop letting a piece of bathroom floor plastic gaslight you every morning. In this episode, Dr. Mark and Dr. Alan break down why "losing weight" and "getting healthy" aren't always on speaking terms. If you’ve ever hit your goal weight only to realize you still feel like a bag of smashed…
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Pirate’s Disease, GLP-1s & The Brain’s “Silent Janitor
Turns out, "Pirate’s Disease" isn't just for 17th-century sailors on wooden ships. This week, we’re breaking down why your modern weight loss journey shouldn't leave you looking like a scurvy soldier. In this episode, we cover: The GLP-1 Nutrition Gap: "Yo ho ho" and a bottle of... Vitamin C? Why...
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Beyond the Gym Bro: The Actual Science of Not Falling Apart
We usually blame aging on gray hair and sensible shoes, but the real culprit is The Great Muscle Vanishing Act. Science is now proving that muscle isn’t just for mirror selfies—it’s actually your primary organ of longevity and your best defense against "throwing your back out while sneezing." In...
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The Other Peptides: What’s Really Behind the Hype?
This week, we take a closer look at the "gray market" peptides often found in fitness circles. These are not FDA-approved medications or natural bioactives; they are "research use only" compounds that sit in a regulatory legal gray area. We looked past the anecdotes to see what the data really...
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The Myths of a Slow Metabolism
In this episode, we’re debunking the biggest myth in fitness: that turning 30 (or 40, or 50) means your metabolism is headed for a permanent vacation. Spoiler alert: Your internal engine is actually doing just fine! The real issue is that we tend to trade the gym for the couch and muscle for......
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Peptides 101 Part Deux
Sorry, we nerded out a little too hard last time. If our last episode felt like a 400-level biochemistry lecture, consider this your palate cleanser. We heard your feedback: the science was heavy, and your brains were full. This week, we’re stripping back the jargon and getting back to basics....
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Peptides 101: Let's get back to the basics!
Think of peptides as the body’s internal group chat—and this week, we’re eavesdropping on the conversation. Join Dr. Mark and Dr. Alan as they strip peptides down to the bare essentials. We’re moving past the buzzwords to explain how these short-chain amino acids act as the ultimate biological...
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GLP-1RA Therapy - Part 2
Welcome back to the sequel your metabolism has been waiting for. In Part 2 of our GLP-1RA deep dive, Dr. Mark Bartlett and Dr. Alan Jones make sure you don’t accidentally trade your biceps for a smaller belt size. While these drugs certainly move the needle, we’re peeling back the curtain on the...
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GLP-1RA Therapy - Part 1
In this opening episode of our two-part series, Dr. Mark Bartlett and Dr. Alan Jones introduce the fundamental science behind GLP-1 receptor agonists, moving beyond the headlines to explore how these therapies actually function within the body. We weigh the significant metabolic benefits against...
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The Pillars of Health - #4: Mental Wellness
In the series finale of the Four Pillars, we’re diving into mental and emotional well-being: the glue that holds your health together (or the reason it falls apart when you see an unwashed dish). From the "overnight therapy" of REM sleep to why your muscles are actually secret mood-boosting…
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The Pillars of Health - #3:Sleep
Welcome to the third leg of our Four Pillars of Health journey, where we’re finally giving sleep the spotlight it deserves. We will dive deep into the world of circadian rhythms, REM dreams, and why your body is actually busier than you think while you’re "resting." We explore everything from the...
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The Pillars of Health - #2: Exercise
We’re stepping into the second installment of our Four Pillars of Health series. Today, we’re moving past the "no pain, no gain" clichés to talk about the actual science of Movement. In this episode, our resident PhDs break down why "movement" is a much bigger category than just your time at the...
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The Pillars of Health - #1: Nutrition
Last week, we laid the blueprint for the Four Pillars of Health. This week? We’re zooming in on Nutrition. We aren't just talking about "eating your greens"—we’re diving deep into the science of macronutrient mastery, the hidden dangers of the "under vs. over" eating trap, and the secret vibrance...
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The Four Pillars of Health Overview
Our bodies can’t run entirely on caffeine and sheer willpower. That's why Dr. Jones and Dr. Bartlett are launching a new series on the foundations of health: nutrition, movement, sleep, and emotional wellbeing. We call them the "Four Pillars," mostly because "The Stuff You Know You Should Do But...
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Peptide PhDs go to Vegas!
What happens when three science geeks trade their lab coats for lanyards and hit Las Vegas? In this episode, our hosts brave the neon jungle of the SupplySide Global Trade Convention—think Disneyland for supplement nerds, minus the churros. Together they hunt for peptides, pan for real scientific...
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Peptide Pillow Talk - How Sleep Drives Repair
Just one day after launching RESTORED, our new restorative sleep peptide, The Peptide PhDs dive into the science of what makes great sleep truly great. We unpack sleep architecture, the rhythms of REM and non-REM, and discoveries reshaping how we understand rest. Deep sleep powers the brain’s...
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A Conversation with Dr. Sarah Outlaw
This week on The Peptide PhDs, Dr. Mark and Dr. Alan sit down with holistic health powerhouse Dr. Sarah Outlaw to talk about what to do when your health or fitness journey hits a wall. We dig into the “why” behind stalled progress, explore practical troubleshooting strategies, and look at how…
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Powerhouse Peptides
Join the Peptide PhDs as Alan and Mark take you on a wild ride “from discovery to delivery” in the world of bioactive peptides! This episode dives into how scientists extract, validate, and manufacture nature’s powerful peptides—think AI-powered discovery, behind-the-scenes lab drama, and the…
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What is Restored?
Struggling with sleep in our always-on world? In this episode, the Peptide PhDs break down the science behind deep and REM sleep, why modern life disrupts our natural rhythms, and how true restorative rest is different from just being knocked out by sedatives. Discover the story behind Restored…
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How Lifestyle Effects Peptide Communication
Ever wondered if your organs are secretly jamming together in a full-blown symphony while you’re out for a jog (or, let’s be honest, just walking to the fridge)? This week, Alan Jones and Dr. Mark Barter are here to spill the science tea on “exerkines”—the rockstar messengers that help your...
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Peptides 101
Make peptides fun again. Dive into into fundamental concepts about peptides, their functions, and the science behind them. In this episode of the Peptide PhDs podcast, Dr. Alan Jones and Dr. Mark Bartlett kick off with humor and introduce the episode's focus on basic peptide education. They...
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ABOUT THIS SHOW
The Peptide PhDs — the show where two science geeks with PhDs turn the complex world of peptides into stories you’ll enjoy. Dr. Mark Bartlett sees peptides as the secret language immune cells use to gossip, negotiate, and sometimes throw shade. Dr. Alan Jones looks at muscle as an endocrine powerhouse, flexing out a vocabulary of peptides that strengthen body and brain.Each week we break down new discoveries from the lab, chat with guest experts, and unleash our cringy dad jokes. We hope it's a fun way to understand how these tiny molecules have a huge impact on health and wellness.
HOSTED BY
MAKE Wellness
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Frequently Asked Questions
How many episodes does The Peptide PhDs Podcast have?
The Peptide PhDs Podcast currently has 38 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is The Peptide PhDs Podcast about?
The Peptide PhDs — the show where two science geeks with PhDs turn the complex world of peptides into stories you’ll enjoy. Dr. Mark Bartlett sees peptides as the secret language immune cells use to gossip, negotiate, and sometimes throw shade. Dr. Alan Jones looks at muscle as an endocrine...
How often does The Peptide PhDs Podcast release new episodes?
The Peptide PhDs Podcast has 38 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to The Peptide PhDs Podcast?
You can listen to The Peptide PhDs Podcast on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts The Peptide PhDs Podcast?
The Peptide PhDs Podcast is created and hosted by MAKE Wellness.
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