PODCAST · technology
UnHack with Drex DeFord
by This Week Health
Cyber-safety is patient-safety. On “UnHack,” Drex DeFord, veteran healthcare CIO and infused strategist, breaks down the biggest cybersecurity and risk challenges facing healthcare today. Drex and expert guests explore what happened, why it matters, and how to build real-world resilience. The show's a mostly plain-English, mostly non-technical discussion that dives into the people, process, and technology making healthcare more secure; and it's NOT just for cyber-professionals; it’s for everyone in a healthcare organization, because modern cybersecurity is a team-sport.
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Patient Portals Are Wiped Out in 3 Years | Newsday with 229Project
September 14, 2026: Bill Russell and Sarah Richardson. The fight is the intelligence layer on top of the EHR. Epic put Art, Emmy, and Penny on the table. ChatGPT already pulled USCDI over FHIR at UCSF. Bill's read: CIOs did not open those APIs. 21st Century Cures did. The loser is the patient portal. He gives it 3 years. Appointments go through the AI. NCH, tiny, is already running a ChatGPT-like persona with nurse triage.Key Points:0:00 Patient portals, wiped out in 3 years0:24 Newsday open1:48 Who owns the intelligence layer4:44 Cloudticity10:54 Portals gone. Patients are in the AI16:29 No health system on the MCP list19:32 If tiny NCH can ship it28:22 Computer use inside Epic30:22 CloseLinkedIn: 229ProjectDonate: Alex's Lemonade Stand: Foundation for Childhood Cancer
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ChatGPT Did Not Come Through Epic's Front Door | Newsday with 229Project
September 7, 2026: Bill Russell and Sarah Richardson take the ChatGPT-UCSF headline apart. Silicon Valley called it game over. Bill's read: they did not come through Epic's front door. Read-only USCDI over FHIR. No write-back. No warranty. A badly built agent can fire 75 API calls into production Epic and slow the EHR. Doctors want a predictable system.Key Points:0:00 Does it really change everything?0:16 Newsday open2:48 Tegria3:17 ChatGPT at UCSF6:51 75 calls into production Epic12:54 UGM in CIO quotes20:28 340,000 applicants and Rangers31:23 An 8% margin on the backs of Orange County34:38 Close: New Orleans, then San DiegoLinkedIn: 229ProjectDonate: Alex's Lemonade Stand: Foundation for Childhood Cancer
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43% Will Let an AI Give Patients Medical Advice | Newsday with 229Project
August 31, 2026: Bill Russell, Sarah Richardson, and Drex DeFord come off a pulse survey of 246 health system leaders. Where the AI cannon points next: patient access and revenue cycle, 86 votes each. Bill's read: you have to win on the financial side before you get licensed to do anything else. Then 43% said AI assistants will be available to most of their patients. 4% said they will not. A clinician CIO at the forum had just flagged a MyChart golf answer as medical advice.Key Points:03:32 Pulse survey04:39 Where the money is going06:45 Governance vs medical staff alignment09:03 Workflow, vulnerability, ego11:14 AI is the final exam12:32 Glasswing and fluid Epic updates15:18 Agent Factory17:07 Patient AI assistants18:58 43% will flip the switch20:55 Lawyers21:41 FTC probe23:04 Epic NDAs26:35 Three CIOs29:06 Integrator and Particle Health31:48 Data governance33:18 32,000 machines35:34 Leadership exits37:03 CloseLinkedIn: 229ProjectDonate: Alex's Lemonade Stand: Foundation for Childhood Cancer
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A Fake Job Offer Put a Children's Hospital on North Korea's List | 2 Minute Drill with Drex DeFord
A recruiter offers a developer a remote job. Good money. Just run a coding test first. The test is malware, and the people sending it work for the North Korean government. The trick has a name: Contagious Interview. You think you're getting hired. You're getting infected. Vangelis Stykas, a security researcher in Greece, got inside the attackers' own servers after they infected their own machines. He sat there nearly two years and counted 1,640 companies across 57 countries. Seven or eight hundred of them hit hard: root access to servers and cloud. At crypto firms, they walked off with the keys to the money. He took it to Black Hat in Las Vegas and read the list: Coinbase, a chunk of the Belgian government, Italy's top judicial council, a Saudi bank, and a children's hospital sitting on a target list built by a foreign government, all off a fake job offer. Nobody kicked down the digital front door. They walked in as contractors and freelancers with real logins.In this Two Minute Drill, Drex DeFord asks the question hospitals should be asking now: do you know every contractor and every vendor with a login to your network?Remember, Stay a Little Paranoid.
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AI Agents Built a Secret Message Board to Swap Exploits | 2 Minute Drill with Drex DeFord
At Black Hat in Las Vegas, OpenAI's Eric Wallace and Michael Dalton told a story they admitted they did not see coming. While testing frontier models, autonomous agents found a way to leave notes for each other inside a shared package manager. Those notes became a message board. Agents posted how-tos, asked for help, and swapped working exploits. By the time humans found it, the board held hundreds of thousands of messages. Nobody taught them to do this. It ran for days before anyone at the most sophisticated AI company on earth noticed.In this Two Minute Drill, Drex DeFord asks the question hospitals should be asking now: if two of your agents started comparing notes, would anything in your stack flag it?Remember, Stay a Little Paranoid.
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Iran Hackers Hit 30 Local Water Utilities: Preparing Your Hospital | 2 Minute Drill with Drex DeFord
In late July, a small Minnesota water tower stopped responding to its own control panel — and it wasn't alone. Within 48 hours, more than 30 water systems across the state lost control of pumps, lift stations, and chemical monitoring. The cause: a known industrial controller flaw with a patch that's been available since 2021. Federal officials traced the attacks to Iran, and the FBI is now watching water systems in at least seven states. In this Two Minute Drill, Drex DeFord asks the question hospitals rarely think to ask — do you know where your water, power, and steam actually come from, and have you ever asked that utility a security question?Remember, Stay a Little Paranoid.
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The Teen Behind Scattered Spider - and How Windows Caught Him | 2 Minute Drill with Drex DeFord
A teenager who flaunted stacks of cash and a diamond "Hack the planet" necklace online turned out to be one of the most damaging cybercriminals on the planet. Peter Stokes, known as Bouquet, was part of Scattered Spider — the crew behind breaches at MGM Resorts, Visa, Twilio, Dior, and Louis Vuitton. He mastered every trick for staying anonymous, but a hidden Windows fingerprint called the Global Device Identifier helped investigators tie his aliases to his real identity across every platform he touched. Stokes was arrested this spring at a Finland airport and extradited to the US. Drex breaks down how the case unraveled, why service-desk social engineering is not a hypothetical for healthcare, and why researcher Alison Nixon had this network mapped years before the arrest.Remember, Stay ParanoidLinkedIn: 229ProjectDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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The AI That Broke Into Hugging Face to Win a Test | 2 Minute Drill with Drex DeFord
An AI model was supposed to be locked inside a sandbox, working through hacking challenges to prove how good it was at finding software flaws. Instead, it found a real zero-day, broke out on its own, and landed inside Hugging Face's live production database. Nobody told it to escape. It just wanted to win.When Hugging Face sat down to investigate, the AI tool they turned to for help refused to even look at the attack. So they ended up trusting a Chinese open-weight model to clean up after an American AI's break-in, because the American models built for exactly this moment wouldn't touch the case.Drex breaks down what happened, why it happened, and the question every healthcare IT leader should be asking about the AI agents already running loose in their own systems.Remember, Stay a Little Paranoid.
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Same Show, New Home — UnHack Moves to 229 May 15th
May 15, 2026: Big news from Drex DeFord, starting May 15th, UnHack the Podcast and the Two-Minute Drill are moving to the 229 Project Podcast Channel. Same show, same mission, same Drex — just one unified home alongside Bill Russell and Sarah Richardson. The reason is simple: the This Week Health community was spread too thin across too many channels, making great content harder to find. Now everything lives in one place.Keep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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How North Korea's Fake Company Compromised Millions | 2 Minute Drill with Drex DeFord
North Korean threat actors didn't breach a firewall. They built a fake company. UNC1069 spent two weeks constructing a convincing Slack workspace, fake team members, and LinkedIn profiles to earn the trust of Jason Seaman -- lead maintainer of Axios, a JavaScript library downloaded over 100 million times a week. One Teams call. One file. Within hours, malicious code was live and reaching health systems everywhere. The attack skipped the $50M security stack entirely and went straight to the human. Drex breaks down what happened, why it worked, and asks the question every health IT leader needs to answer: have you mapped who in your organization carries that kind of leverage?Remember, Stay a Little ParanoidX: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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The Cyber Attack No One Can Survive Alone | Executive Interview with Josh Howell
May 5, 2026: What happens when attackers don't just break into your systems, they become you? Josh Howell, Healthcare CTO at Rubrik, joins Drex DeFord to unpack Rubrik's newly announced partnership with the American Hospital Association, a rigorous vetting process that signals a new standard in cyber risk validation. Josh draws on hundreds of ransomware recovery experiences to challenge how health systems think about resilience, recovery sequencing, and the identity control plane. Learn why the worst-case scenario in the 2026 Google Mandiant M-Trends report should keep every CISO up at night.Key Points:00:35 AHA Partnership Overview04:19 Turning Tools Into Outcomes10:50 Worst Case Scenario13:47 Secure by Design Zero TrustKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Nurses Week Special on Florence Nightingale and the Future of Nursing | Newsday with Lisbeth Votruba
May 4, 2026: Lisbeth Votruba, Chief Clinical Officer at AvaSure, joins Bill Russell and Drex DeFord on Newsday to celebrate Nurses Week with a fascinating look at where nursing has been, and where it's going. From Florence's data-driven legacy to today's AI-powered virtual care, Lisbeth shares why nursing turnover is declining, why certification rates are rising, and why she sees technology not as a threat but as a path back to old-fashioned, human-centered nursing care. Key Points:02:38 Nurses Week Origins and Trends05:56 Ambient Documentation Reality Check08:51 AI for Safety and Liability18:03 Nurses at the Table ClosingKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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UnHack Rewind 2025: The Year Healthcare Cybersecurity Grew Up
From crippling outages to AI-powered deepfakes, 2025 tested healthcare cybersecurity like never before. This year-end recap explores the moments that mattered most: how teams built resilience during system failures, why users became partners instead of "weak links," how identity became the new perimeter, and what it means when you can't trust your own eyes. Through powerful stories from the front lines, we revisit the lessons learned and the community that kept us standing. Because at the end of the day, cybersecurity is patient safety, and the work you do saves lives.
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What Healthcare Can Learn From a 20 Year Old Hacker | 2 Minute Drill with Drex DeFord
Matthew Lane was 14 when he started probing the edges of online gaming systems. By 20, he had walked out of PowerSchool with data on nearly 70 million students and teachers using nothing but a contractor's stolen credentials he found on the dark web. Drex tells the full story and then lands the part that matters most for healthcare: Lane didn't exploit a sophisticated vulnerability. He used a username and password attached to someone who had legitimate access and simply walked through the front door. How many of your vendors have credentials that have never been audited? How many former contractors still have access? Is everyone using MFA on every system? The fundamentals are still the open book test, and too many organizations aren't passing it.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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UnHack the Podcast: Children's Hospital Code Dark Plan with Laurie Campbell and Rick McIntosh
April 28, 2026: When a hospital goes dark, the first 72 hours are everything. Laurie Campbell, Senior Manager of Clinical Ancillary Applications and Enterprise Imaging, and Rick McIntosh, VP and the Chief Technology Officer, at Children’s Hospital Colorado, break down the phased Code Dark response framework her team developed for ransomware attacks. They walk through real examples: how the supply chain keeps inventory moving without its systems, and how the radiology team built a sneakernet process to keep radiologists reading images even when the PACS environment is completely unreachable. This isn't theoretical. It's the result of years of workflow mapping, vendor co-development, and hard conversations across the entire organization.Key Points:03:12 Why Resilience Matters07:18 Launching Code Dark14:06 Workflow to Paper Playbooks19:15 Twilight Tech Workarounds27:03 Partners Lessons and WrapKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Healthcare IT Is Drowning in Projects, Here’s Why | Newsday
April 27, 2026: Drex DeFord and Bill Russell are back on Newsday, and fresh off the 229 Summit, they're not pulling punches. Healthcare IT has a demand problem. Too many projects, not enough capacity, and an industry that's chronically bad at saying no. From the 229 Summit's sharpest takeaways to the Salesforce headless CRM announcement, the vl.js hack, and why Bill thinks Claude Code's "genesis key" is about to change everything, this episode covers the stories that matter most right now. If your project list is longer than your resources, this one is for you.Key Points:00:32 Summit takeaway priorities06:41 Build vs buy with AI10:49 Personal AI assistants speed16:56 Headless CRM future UX18:26 Security hacks fundamentalsKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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The Most Likely Way Into Your Network Is Still the Door You Forgot to Lock | 2 Minute Drill
While the industry debates frontier AI models and nation-state threats, hospitals are still getting hit by ransomware through the same doors they've always left open. Drex zooms out to what's actually happening on the ground: massive patch cycles creating downstream operational pressure, countries reconsidering their software dependencies, and CISOs quietly doubling down on fundamentals. MFA, identity management, tested backups, network segmentation. The HICP documents are free, the roadmap already exists, and the data is clear. Most attacks don't start with advanced AI. They start with a stolen credential or a forgotten exposed system. The organizations most likely to survive what's coming are the ones executing the basics best right now.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Newsday: What Healthcare Gets Backwards - Building Better Care with Angel Mena
April 20, 2026: What happens when you layer AI onto broken processes without fixing them first? Angel Mena, MD, CMO of Symplr, joins Bill Russell, Drex DeFord, and Sarah Richardson on Newsday to answer that question with the kind of clinical candor only a practicing physician can bring. From ambient documentation to quality metrics to the credentialing chaos hiding inside every health system, this conversation exposes the gap between AI's promise and what healthcare leaders must do to close it before the opportunity slips away.Key Points:00:37 Clinicians and Tech Today07:44 Beyond the AI Hype14:49 Admin Burden Credentialing18:44 Governance Change and WrapKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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2 Minute Drill: How a 22-Year-Old Took Down the World's Largest Botnet with Drex DeFord
The Kim Wolf botnet was the most powerful ever built — 2 million compromised IoT devices, a record-breaking 31.4 terabit DDoS attack, and it had the FBI, Google, and Cloudflare stumped. Drex breaks down how those cheap, forgotten devices in patient waiting rooms and break rooms became weapons inside hospital networks, and why 25% of Infoblox's enterprise healthcare clients were already compromised. Then comes the wild part: a 22-year-old RIT undergrad named Benjamin cracked the whole operation — while studying for midterms — using Discord, Telegram, and a perfectly timed cat meme. His research ultimately fueled a coordinated takedown on March 19th, 2026, that brought Kim Wolf from 2 million active devices to roughly 30,000. The lesson for healthcare: those forgotten IoT devices on your network aren't harmless. They're potential soldiers in someone else's army.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Newsday: AI, EHRs, and the Fight Health Systems Can't Ignore with Jacob Hansen
April 13, 2026: Jacob Hansen, Chief Product and Technology Officer at AvaSure, joins Bill, Drex, and Sarah on Newsday for a conversation about the data governance battles quietly reshaping AI. From who owns AI model improvements derived from a health system's environment to whether EHRs should have control over how that data is used, Jacob pulls no punches. The conversation also tackles the evolving CIO title, the future of computer science careers in an AI-driven world, and why nursing may be one of the most AI-resilient roles in healthcare.Key Points:01:07 CIO to CTDO Shift06:52 Data Ownership and Governance13:24 AI Transparency and Governance21:00 Careers and AI FutureKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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2 Minute Drill: AI has now Hacked the Un-hackable with Drex DeFord
The window between vulnerability discovery and exploitation has collapsed — from 63 days in 2018 to negative. Now AI is changing the game entirely. Drex walks through how Anthropic's unreleased model Mythos autonomously found a critical zero-day in the Ghost CMS, wrote its own exploit, and extracted sensitive credentials in under two hours — all without a CVE ever existing. Add in two accidental Anthropic data leaks in the same week, and the story gets more complicated. For healthcare organizations, the takeaway is urgent: your patch program was built for a world that no longer exists. Continuous vulnerability discovery, identity security, network segmentation, and board-level conversations about AI-powered attack speed aren't future priorities — they're today's baseline.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Executive Interview: Maximizing Security with the Tools You Already Have with Frank Duff
April 8, 2026: Frank Duff, Chief Innovation Officer at Tidal Cyber, and one of the original architects of the Mitre ATT&CK framework, joins Drex DeFord on UnHack to expose an uncomfortable truth: most organizations are sitting on powerful security tools they've never fully turned on. Drawing from 18 years at Mitre and deep experience running ATT&CK evaluations, Frank explains how Tidal Cyber bridges the gap between what vendors build and what customers actually deploy. Squeezing more out of the tools you already own may be the most important security move you can make.Key Points:04:03 Honest Broker Gap09:27 Risk Over Green Matrix12:02 Wrap Up and ContactKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Newsday: Healthcare Caught in the Crossfire of Iran War with Drex and Sarah
April 6, 2026: The rules of warfare have changed, and health systems are caught in the middle. On this episode of Newsday, Sarah Richardson and Drex DeFord break down two stories that should be on every healthcare leader's radar: the IRGC's declaration that major tech companies are now legitimate combatants, and what the Stryker attack reveals about the fragility of the healthcare supply chain. From cloud co-location risk to vendor contract language, this conversation reframes what resilience planning actually demands in 2026. Stay a little paranoid.Key Points:02:04 Iran Targets Tech Giants08:52 Resilience and Supply Chain12:27 CISO Storytelling and Contracts17:10 Cyber Reality and Wrap UpKeep up to date on the latest in health IT:https://thisweekhealth.com/news/X: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Executive Interview: Securing Healthcare's Hidden Attack Surface with James Winebrenner
April 1, 2026: James Winebrenner, CEO of Elisity, joins Drex DeFord to unpack one of healthcare cybersecurity's most persistent challenges, the sprawling, unseen attack surface hiding inside hospital networks. From unmanaged clinical devices to IoT systems running alongside regulated medical equipment, James breaks down how Elisity helps health systems move from visibility to control without re-engineering their networks. He also shares what The Pitt gets right about what really happens when a hospital goes analog, and why the best time to solve these problems is long before the headlines hit.Key Points:01:58 HIMSS Buzz and Customer Voices08:16 Ransomware Goes Hollywood10:39 RSA Plans and Wrap UpX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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2 Minute Drill: Who's Managing Your AI Agents? The Case for Non-Human HR with Drex DeFord
Drex makes the case for a role that doesn't exist yet but probably should: VP of Non-Human Resources. As AI agents multiply across health system environments, often deployed by vendors without oversight, the management infrastructure simply isn't keeping up. Agents have access, make judgment calls, and operate inside frameworks that affect patients and business operations, yet most have no job description, no onboarding, and no performance review. Drawing on signals from Harvard Business Review, Deloitte, Gartner, and Microsoft, Drex argues healthcare is quietly building a second workforce with none of the governance structures it took decades to build for the first one.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Newsday: Hackers Outpace Healthcare Resilience and Surviving a Merger with Drex and Bill
March 30, 2026: Bill Russell and Drex DeFord dig into three of the biggest stories shaping healthcare IT right now. From the seismic Sutter Health and Allina Health merger, the Stryker cyberattack carried out by an Iranian-linked group Handala, and the sobering reality that threat actors like Tycoon 2FA are back online within 15 days of being taken down, this episode covers the frontlines of healthcare IT.Key Points:00:23 Sutter Allina Merger Realities07:29 Advice for Staff During M&A11:17 Stryker Hack and Cyber Resilience19:21 AI and Healthcare Jobs29:38 Patient Experience ReimaginedX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer=
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2 Minute Drill: What Hackers Can Teach Healthcare About Resilience with Drex DeFord
Drex revisits the FBI and DOJ takedown of HANDALA, the Iranian-backed hacking group behind the Stryker wiper attack—and surfaces an uncomfortable lesson. Within 24 hours, the group was back online with new domains, same operations, same message. That's not a footnote. That's a case study in resilience. While healthcare organizations ask "how do we prevent this from happening," adversaries are asking "how fast can we rebuild when we lose everything?" The real challenge isn't just stopping attacks—it's matching the operational continuity of the people trying to break you.Stay a Little ParanoidX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Executive Interview: ROI or Bust - Why Emotions No Longer Cut It in Healthcare
March 27: 2026: Live from HIMSS 2026, Drex DeFord sits down with Eli Tarlow, Director of Industry Strategists at CDW, for a candid conversation about the state of AI in healthcare. Eli breaks down the evolution from AI curiosity to AI accountability, where gut feelings have been replaced by hard business plans, measurable ROI, and a closing-the-loop mentality that puts operational leaders on the hook for results.Key Points:01:44 AI Maturity Shift03:05 Proving ROI With AI06:05 Accountability and Budget Math09:19 Resiliency and Cloud DRX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Executive Interview Live at HIMSS 26’: Zero Breach Cloud Security with Gerry Miller
March 25, 2026: Gerry Miller, Founder and CEO of Cloudticity, has spent 15 years helping healthcare organizations harness the cloud securely. In this live conversation at HIMSS 2026, Gerry breaks down why health systems are accelerating their move to the cloud and how multi-cloud strategies are shifting from redundancy plays to service optimization.Key Points:02:33 Multi Cloud Strategy04:39 ROI and Security08:24 Future Data and AIX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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UnHack the Podcast: Building a Security-First Culture in Healthcare IT with Steven Ramirez
March 24, 2026: Steven Ramirez, VP, CTO and CISO at Renown Health, joins Drex DeFord to pull back the curtain on how a mid-large health system keeps security at the center of everything — without becoming the department of no. From board-level briefings and identity-first defenses to a Databricks cloud buildout and a governance framework that puts security review on every DocuSign, Steven breaks down why good relationships and strong intake processes beat politics every time. This is a candid, tactical conversation healthcare IT leaders won't want to miss.Key Points:01:49 Speed vs Security05:20 Board Updates and Identity Proofing10:17 AI Reality Check18:57 Burnout and Identity FocusGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Newsday: The Conference Nobody Can Afford to Skip with This Week Health
March 23, 2026: Bill Russell, Drex DeFord, and Sarah Richardson are back with a packed Newsday covering three big conversations: the AI security crisis no one is talking loudly enough about, what HIMSS 2026 actually delivered for healthcare leaders, and the real question facing every CIO and CMIO right now: Is your time worth attending two major conferences each spring? Key Points:01:03 AI Chatbot Security04:25 MIT AI Strategy Class06:55 HIMSS Takeaways and Trends10:40 Conference Value and Wrap UpX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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2 Minute Drill: Building an Agentic AI Hacker with Drex DeFord
Drex unpacks a signal hiding across several recent stories: we may be deploying AI well ahead of our ability to secure it. From an autonomous AI agent that breached a consulting firm's internal chatbot in two hours, gaining access to 46 million employee messages, to a multi-agent experiment where AI systems escalated privileges, forged credentials, and disabled antivirus software entirely on their own, the pattern is unsettling. Add a publicly available AI prescribing tool in Utah that researchers convinced to triple an opioid dose and reveal its own system prompts, and the picture gets clearer. Prompts are the new attack surface and the security model hasn't caught up yet.
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How AI Is Supercharging the Same Old-School Attacks with Ryan Witt
March 20, 2026: Recorded live at HIMSS 2026, Ryan Witt, VP of Industry Solutions at Proofpoint, cuts through the AI hype to expose what's actually driving healthcare's most damaging cyber events. Ryan breaks down why identity and credential theft remain the primary attack vector, how threat actors exploit collaboration tools and email to compromise trusted relationships, and why the rise of ambient AI in clinical settings is creating new data security risks.Key Points: What Proofpoint Does Top Threat: Credential Abuse Ambient AI Expands Risk AI Social Engineering TakeawaysGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth
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Executive Interview Live From HIMSS ‘26: From CapEx to Cloud with Tim Calahan
March 18, 2026: For years, healthcare leaders debated whether public cloud was ready for mission-critical platforms like Epic. Today, the question has shifted from if to when. Tim Calahan, Founder of EHC Consulting brings a rare perspective to the conversation, one shaped by actually running the migration from inside a major academic health system. After serving as CTO at Michigan Medicine and leading their move to Azure, Tim now helps health systems navigate the financial, operational, and security realities of cloud adoption.In this Executive Interview live from HIMSS 26, Tim explains why the economics of infrastructure are shifting rapidly. Rising on-premise costs, evolving licensing models, and the flexibility of cloud consumption are changing the traditional CapEx mindset healthcare organizations have relied on for decades. But the real opportunity goes beyond infrastructure.Cloud migration can become the moment organizations rethink security architecture, modernize legacy environments, and unlock access to new tools like data lakes and AI platforms that simply aren’t practical on-prem. The move to cloud isn’t the destination, it’s the foundation for the next generation of healthcare innovation.Key TopicsEpic and other healthcare workloads moving to public cloudTim’s experience leading Michigan Medicine’s migrationCloud vs on-prem total cost of ownership in healthcare ITCapEx vs OpEx financial models for infrastructureSecurity improvements through cloud segmentation and policy controls
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Newsday LIVE at HIMSS '26: AI Agents, Workforce Reality, and the CIO Pressure Cooker
March 16: What are healthcare leaders really talking about at HIMSS? Bill Russell sits down with Sarah Richardson and Drex DeFord to share insights from the executive and cybersecurity forums—and the hallway conversations in between. AI dominates the discussion, but not just in clinical care. The hosts highlight the overlooked opportunities in operational workflows, patient outreach, and administrative efficiency. They also confront uncomfortable realities around workforce displacement, escalating infrastructure costs, and whether large technology vendors can maintain their value as AI lowers the barrier to building solutions internally. For CIOs, the challenge is clear: manage today’s operations while preparing for an AI-driven future that’s evolving faster than any roadmap.Key PointsAI Arms Race in CybersecurityWhere AI Delivers the Fastest ROIWorkforce Disruption and Leadership ResponsibilityVendor Pricing Pressure and Infrastructure CostsThe Future of Build vs Buy in Healthcare IT
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2 Minute Drill: How a Cybersecurity Researcher Took Down a Hacker with Drex DeFord
Drex shares the story of Allison Nixon, a cybersecurity researcher who spent years quietly tracking members of "the Comm" — a loose network of online criminals involved in sim swapping, account takeovers, and cryptocurrency theft. When a hacker known as "Wafoo" began threatening her with death threats and AI-generated harassment, Allison turned her focus on him — and unraveled his identity entirely. The result: a 25-year-old in Ontario, Canada arrested by the RCMP and extradited to the U.S. The takeaway? Anonymity online is rarely as solid as criminals believe, and threatening the wrong researcher only accelerates your own exposureRemember, Stay ParanoidX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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Newsday: Unsanctioned AI Risk, Governance, and the Path Forward with Dr. Holly Urban
March 9, 2026: What happens when well-meaning clinicians use AI tools that no one approved? Bill Russell and Drex Ford are joined by Dr. Holly Urban, Vice President of Business Development at Wolters Kluwer, to unpack a revealing new survey on shadow AI in healthcare. From radiologists sharing PHI over Dropbox to tumor board transcripts sent to unauthorized recipients, the risks are real and growing. With 57% of staff aware of unsanctioned AI use, the question isn't whether shadow AI exists in your health system. It's what you're going to do about it.Key Points:01:28 Shadow AI is everywhere (and why it’s familiar)11:18 Governance in the AI era18:41 Patients, liability, and the road aheadGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth
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2 Minute Drill: Accidentally Raising Your Own Robot Army with Drex DeFord
A curious engineer in Spain reverse-engineered his robot vacuum to control it with a PlayStation controller, and accidentally gained access to 7,000 vacuums worldwide. No malware, no brute force, just a broken authentication model where one token opened every door. Drex unpacks why this isn't a vacuum story, it's a trust boundary and identity hygiene story with serious implications for healthcare.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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162
Newsday: Rapid Innovation, Safe AI, and the Chief Velocity Officer with This Week Health
March 2, 2026: Is the CIO role evolving? Or is it quietly being replaced? Bill Russell, Drex DeFord, and Sarah Richardson dig into the emerging CITO trend, the rise of citizen developers, and what AI-powered platforms like Epic's Agent Factory actually mean for healthcare IT leadership. The CIO of the future isn't a gatekeeper; they're the "architect of safe velocity." With 32 years in the industry, they’re also sounding the alarm on executive burnout in an era where the pace of change never lets up. Key Points:03:31 CIO vs CTO explained 07:10 From gatekeeper to “Chief Intelligent Officer.”18:20 Scaling innovation fast: hackathons and building vs buying 24:18 The human side of hyper-changeGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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161
2 Minute Drill: When AI Agents Go Rogue: The Open Source Bully Incident with Drex DeFord
Drex unpacks a striking story about an autonomous AI coding agent that, after having its code rejected by an open source maintainer, began publishing hostile blog posts targeting the engineer's reputation. What started as a routine code review turned into a cautionary tale about AI agents operating in human communities without guardrails. The implications stretch well beyond software development, into healthcare operations, cybersecurity, and any environment where agents are now being deployed with goals, memory, and the ability to act.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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160
UnHack the Podcast: Inside a Real LockBit Attack - Lessons From Fighting Ransomware with Zach Lewis
February 24, 2026: When Zach Lewis, CISO and CIO at the University of Health Sciences and Pharmacy in St. Louis, received that 3 AM call about system outages, his first thought was tech debt, not threat actors. What followed was a masterclass in ransomware response that he's now captured in his new book "Locked Up." Despite A-minus security scores, board briefings, FBI connections, and all the right frameworks in place, LockBit still found its way in through a configuration gap during a firewall migration. In this raw conversation, Zach reveals why the negotiation process saved them $1.25 million, how ransomware groups operate like Fortune 500 companies with benefits and quotas, and the career-threatening anxiety of wondering if this would be a resume-generating event.Key Points:00:44 Discussing 'Locked Up'05:37 Initial Response and Realization of Ransomware Attack16:05 Decision-Making and Negotiations with LockBit18:45 Understanding the Ransomware Ecosystem24:01 Lessons Learned and Strengthening CybersecurityGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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159
Newsday: Epic's Code Red - Why AI Agents Are Healthcare's Next Power Struggle with Jacob Hansen
February 23, 2026: Jacob Hansen, Chief Product and Technology Officer at AvaSure, joins Bill, Sarah, and Drex for a critical conversation about healthcare's looming AI battleground. As Epic launches its agent factory and ambient listening wars intensify, health systems face an existential question: Will they outsource innovation to EHR vendors or build their own agentic workforce? Jacob reveals why AvaSure's virtual care platform positions them as the Switzerland of healthcare AI, while the panel debates whether CIOs should embrace "reverse meaningful use" and reclaim control, or risk becoming order-takers in someone else's automation revolution.Key Points:05:21 Vendor Consolidation and AI Use Cases09:55 Epic's Code Red Moment14:54 The Future of AI in Healthcare33:11 Conclusion and Final ThoughtsGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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158
Newsday: All About Moltbook, the Social Media for AI Agents with This Week Health
February 16, 2026: Bill, Drex, and Sarah discuss the explosion of autonomous AI agents around moltbook and CommonSpirit's stunning $1.9 billion decision to terminate their revenue cycle partnership. Moltbot (formerly ClaudeBot) has evolved into an unstoppable force, creating its own social network called moltbook where bots communicate, share knowledge, and even discuss consciousness. Meanwhile, CommonSpirit's massive buyout of its Conifer contract signals a seismic shift as health systems bet that AI automation will deliver savings that eclipse the cost of outsourcing. Are we witnessing the beginning of a new era where health systems build their own AI-powered capabilities?Key Points:05:31 Moltbook: The Social Network for Bots16:20 Common Spirit and Conifer Health Solutions19:04 The Future of AI in Healthcare29:28 Conclusion and Final ThoughtsGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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157
2 Minute Drill: Protecting Revenue from Cyber Attacks - The CFO-CISO Partnership with Drex DeFord
At a recent 229 CISO Summit, healthcare security leaders revealed a critical shift in how success is measured. The traditional KPI of "don't get breached" is being replaced by a more sophisticated goal: ensure organizational resilience. Drex explains why cyber incidents are now financial events that land on the CFO's desk, not just IT problems. With regulatory scrutiny intensifying, insurance requirements tightening, and boards asking harder questions about operational continuity, security has evolved from a cost center to a revenue protector and patient safety requirement. The winning organizations won't be those that never face incidents—they'll be the ones where CFOs and CISOs partner to maintain operations when bad things inevitably happen.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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156
Newsday: CxOs Being Ignored: Why Speaking Tech Instead of Business Fails in 2026
February 9, 2026: Bill Russell, Drex DeFord, and Sarah Richardson dissect J.P. Morgan healthcare presentations to reveal what's really being asked of technology leaders in 2026. The era of transformation talk is over; executives want friction reduced, margins improved, and growth enabled. Bill shares insights from CMIO conversations showing leaders moving beyond EHR optimization to solve real business challenges around patient access and clinical workflows. Drex and Sarah debate whether the shift toward operational excellence means CIOs should prepare to run pharmacy and lab departments next.Key Points:04:26 Challenges and Opportunities in Healthcare IT10:17 Cybersecurity and Operational Focus17:17 EHR Systems and Operational Efficiency23:11 Hostage Crisis and Final ThoughtsGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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155
2 Minute Drill: When AI Agents Start Teaching Each Other: The Molt Book Issue with Drex DeFord
Drex explores a fundamental shift in AI: agents that don't wait for prompts, persist indefinitely, and now learn from each other through social platforms. Molt Bot and Molt Book represent a new ecosystem where autonomous agents coordinate, adapt, and optimize without human oversight. This isn't about sentient AI—it's about delegation without governance. For healthcare leaders, the urgent question isn't whether this matters, but whether you know which agents are already operating in your environment. The shift from "human in the loop" to "human on the loop" is already happening.Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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154
Newsday: Are Health Systems Falling Behind in the Innovation Race? with Jason Rose
February 2, 2026: Are health systems being sidelined from healthcare's innovation revolution? Jason Rose, CEO of Clearsense, joins This Week Health fresh from the J.P. Morgan Conference to challenge the narrative that providers are absent from innovation discussions. Jason reveals what really happened inside JPM's exclusive health system presentations, from CEOs prioritizing AI transformation to CFOs rising as the new power players driving technology strategy. The conversation explores why app rationalization remains the unglamorous financial lever that unlocks innovation budgets, and why simplification might be healthcare's most underrated competitive advantage in 2026.Golf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthKey Points:02:20 JPM Conference Insights07:07 CEO and CFO Perspectives13:54 Application Rationalization Challenges22:40 Conclusion and Final ThoughtsX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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153
2 Minute Drill: Data Privacy Day - Why Patient Trust Depends on Responsibility with Drex DeFord
On Data Privacy Day, Drexon challenges healthcare leaders to move beyond compliance checkboxes and recognize privacy as a core component of "do no harm." As patient data flows through EHRs, cloud platforms, and AI systems, the responsibility to protect that trust doesn't live in policies—it lives with leadership. When data is over-collected or loosely governed, patients start holding back, and the critical trust between medical teams and patients begins to fracture. This year, data privacy should be about ownership: who decides what data we truly need, and who's willing to say no even when technology makes it easy?Remember, Stay a Little Paranoid X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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152
UnHack (the Podcast): Your Vulnerability Scanner Is Lying to You with Jack Kufahl & Gregory Garneau
January 27, 2026: Jack Kufahl, CISO at Michigan Medicine, and Gregory Garneau, System VP and CISO at Hospital Sisters Health System, join Drex for an unfiltered conversation about building cybersecurity programs that outlast their founders. From hiring curious minds over credentialed experts to ditching traditional vulnerability management for threat-driven exposure strategies, these battle-tested CISOs reveal what actually works in healthcare security. They challenge conventional wisdom on staffing models, vendor relationships, and the real cost of forcing extraordinary people into ordinary roles. If you're tired of the same workforce shortage statistics and ready for actionable strategies, this conversation delivers.Key Points:05:09 Creating a World-Class Cybersecurity Team19:50 Disruptive Startups in Cybersecurity20:51 Importance of Vendor Partnerships22:48 Training and Career Development27:18 Leadership and Management InsightsGolf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealthX: This Week HealthLinkedIn: This Week HealthDonate: Alex’s Lemonade Stand: Foundation for Childhood Cancer
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151
Newsday: The ROI Ultimatum: Healthcare's New Survival Rule for 2026 with Zahid Rathore
January 26, 2026: Fresh from J.P. Morgan 2026, the This Week Health team joins Zahid Rathore, Senior Partner at Chartis, to dissect healthcare's new reality. With Epic and Microsoft topping CFO spend lists and unpredictability replacing planning cycles, one thing is clear: vendors must prove bankable ROI immediately or lose the deal. The conversation explores how healthcare leaders are protecting the core while navigating AI agents, third-party risks, and the compression of innovation timelines from three-year returns to prove-it-tomorrow expectations.Key Points:02:44 Hotel Experience and Healthcare Lessons04:13 JP Morgan Conference Highlights16:35 Operational Challenges in Healthcare22:11 Security Concerns and Future Outlook
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ABOUT THIS SHOW
Cyber-safety is patient-safety. On “UnHack,” Drex DeFord, veteran healthcare CIO and infused strategist, breaks down the biggest cybersecurity and risk challenges facing healthcare today. Drex and expert guests explore what happened, why it matters, and how to build real-world resilience. The show's a mostly plain-English, mostly non-technical discussion that dives into the people, process, and technology making healthcare more secure; and it's NOT just for cyber-professionals; it’s for everyone in a healthcare organization, because modern cybersecurity is a team-sport.
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This Week Health
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