A Dose of Reality with Charles Spence cover art

All Episodes

A Dose of Reality with Charles Spence — 71 episodes

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Title
1

Tobias Kampfenkel, MD, MHBA, Vice President of Early Clinical Development and Translational Research at Miltenyi Biomedicine, on Transformative Drugs in Oncology and Autoimmunity: It's Always the Team!

2

Sofia Heigis, CEO of OncoPeptides, From Sales Rep to CEO, Being "Present", and Hiring for Self-Insight

3

Jens Lindberg, CEO at Medivir, on The Biotech Rollercoaster - Medivir´s Previous Four Months (and Biotech Today in 2026)

4

Hubert Truebel, Managing Director at DEBRA Research, on Creating Own Career Opportunities...and a Practical Approach to Longevity

5

Sampreet Ramachandra, Head of Hematology Business Unit at Novartis Germany, on Launching Without a Playbook, Hiring Mistakes, and Leading with Equity

6

Volker Wacheck, SVP at Taiho Oncology in Speaking Up, Asking vs. Accusing and Why Culture is So Important

7

Dena Grayson, MD, PhD, SVP Clinical Development & Medical Affairs at Kyverna Therapeutics on Media Training, Communication within Biotech, and Dealing with Fake CVs

8

Richard Nkulikiyinka, Chief Medical Officer at Antag Therapeutics, on Career Pivots, Trust and Why Leadership Is Never Linear

9

Prof. Dr. med. Markus Kosch, Head of Oncology Europe & Canada at Daiichi Sankyo on Perseverance, Patient-Centricity Beyond Slogans, and Leadership within Oncology

10

Myriam Cherif, Founder of Kalyx Medical, on The Future of MSLs, Adapting to AI, and Why Curiosity Keeps You Moving Forward

11

Sven Van den Berghe, CEO of Pantera on Overpromises in Isotope Marketing, Why Culture is the Company, and Discussions in RLT Development

12

Catello Somma, Partner at Seroba on Working in VC, Non-Linear Biotech Careers, and advice for those seeking VC careers

13

Kevin N. Heller, MD, Chief Medical Officer and Advisor to Funds and VCs, on Culture Shifts, Tough Lessons In Leadership, And The Reality Of Biotech Fundraising

14

Carl Deutsch, CSO at NBE Therapeutics in Non-Linear Careers, Age Bias, and Building Great Teams

15

Aleksandra Filipovic, Chief Medical Officer at Gallop Oncology on Perfectionism, Intuition, and the Risk of Building Unsafe Teams

16

Heidi Wang, CEO at OBI Pharma & Chairwoman at OBIGEN Pharma on Losing Her Father to Cancer, Hiring Without Humility, and Building a Culture That Lasts

17

András Strassz, MD, MBA, CMO at Heidelberg Pharma – Career Crossroads, Recruiting, and Culture Fit Over CVs

18

Steven Katz, MD, CMO and SVP of Translational Science for Shinobi Therapeutics & Professor of Surgery at Brown University - Hiring Without Regret, Team Mismatches, and the Cost of Playing It Safe in Biotech

19

Christian Mueller, CDO at Immutep on Career Crossroads, Culture Missteps, and the Recruitment Disconnect in Biotech

20

Kirsty Crame-van Nierop, Director of Shiaba Consulting, Specialist on Clinical Drug Development, in Broken Hiring Cycles, IND Wins, and Surviving Biotech Burnout

21

Bernhardt Zeiher, M.D. Member of the board of directors for Entrada Therapeutics, Amylyx Pharmaceuticals, and Abeona Therapeutics on Lessons from Leading a Global Development Organization

22

Ilya Gipp, CMO at GE Healthcare – Imaging’s Role in Oncology, Hiring Lessons, and How Culture Really Works

23

Michael Lahn, CMO at iOnctura – Osimertinib Success, TGF-Beta Lessons, Building Curious Teams, and More

24

Johan Baeck, EVP and CMO at Promontory Therapeutics – Cultural Fit in Hiring, Immunogenic Small Molecules, and Building Resilience in Biotech

25

Peter Tummino, President of R&D at Nimbus Therapeutics – Drugging the Undruggable, The TYK2 Success Story, and Overhyping AI in Drug Discovery

26

Abigail Jenkins, CEO and Board Member – From Government Scientist to CEO, Launching a Stem Cell Therapy During Crisis, and Lessons in Commercial Strategy

27

Joseph Birkett, Executive Director at Aura Biosciences – Obinutuzumab's Approval, CDK9 Trial Regret, CRO Reliance, and Building Respectful Cultures

28

Bruce Dezube, Senior Vice President, Clinical Development at Xilio Therapeutics – HIV & Cancer Drug Development, Career at 60, Building Respectful Teams, and More

29

Chris Lowe, CEO at Nusano - Radioisotopes, Volunteering in Hospitals, Culture Building, and More

30

Kevin Lynch, co-Founder PopulusBio - Career at Celgene, How Culture Influences Drug Development and more

31

Victor Paulus, SVP Regulatory Affairs at ARTBIO - Lutathera Approval and Lessons, Falling from Trees, ARTBIO's Culture

32

Chris Leamon, CSO at Fusion Therapeutics - Acquisition of Endocyte, Career reflections and more

33

Dawn Rubel, President R&D at NexEos Bio - Eosinophilic Esophagitis, Purposeful Leadership and more

34

Örn Almarsson, Co-Founder of Axelyf - Modernas SpikeVax, the challenge of mRNA delivery and Salmon's inspiration behind Axelyf?

35

Leila Jaafar, CEO at Nuclidium - from PhD to Radiotherapy CEO

36

CMO at Indaptus, Roger Waltzman, on Dangers of Pushing Uncertain Data into Phase III

37

Gertjan Bartlema, Co-founder Populus Bio and CEO of Immodulon Therapeutics. on Innovation in Biotechs

38

The 3 Most Common Rejection Reasons During an Interview

39

The Most Common Hiring Mistakes by Hiring Managers in 2024 ft. Caroline Vermeulen, Eminence

40

How and When to Ask Intelligent Interview Questions

41

Troels Jordansen, Executive Chairman of Keli Therapeutics, on Cell Therapy and Biotech Recession Talks

42

Negotiation Strategies and Insights from Harvard Course ft. Sophie He, Head of M&A and Partnering at Bracco

43

The 3 Interview Questions You Must Succeed In

44

Nikolaus Trede, SVP Clinical Development at Century Therapeutics - Lessons from Breyanzi and Global Cell Therapy Trials

45

Re-Entering the Workforce and Career Growth in Regulatory Affairs with Mary Christian

46

From Neuroscientist to Biotech Innovator ft.Anita Scheuber

47

Future-Proofing Your Organization Ft. Jackie Donovan

48

The Critical Role of Recruiters ft. Patrizio Renzetti

49

Bad Science vs. Good Leadership in Biotech ft. Sonal Kothari-Gupta, MD, PhD

50

Recruitment Strategies for High-Impact Hires with John Goldener

51

Hiring Strategies for Biotech Success ft. Sumeet Ambarkhane CMO at Alligator Bioscience

52

How to Outsource Your Job Search

53

Stealth biotech work, moving China trials to the US and more ft. Li Yan, former CMO of Brii and current CEO of upcoming stealth biotech

54

Building powerful relationships ft. Val Nassiri, previous VP of Medical Affairs at ITM and AAA.

55

Using Empathy to Build Internal Support

56

Sabine Brookman May VP Janssen - Listening in leadership, making beer and a career in drug development

57

The Biggest Selling Myth: Selling Through Talking

58

Effective Layoffs and treating people as humans ft. Crystal Zuckerman

59

Improve Your Selling Ability to Help Your Career

60

BIOSECURE Act - The potential $3.6bn+ gap, Impact on Jobs and Skills shifts with Amber Tong, Senior Editor at EndPoint News

61

My 10 Commandments to Recruitment

62

Discussions on Leadership, Hard decisions and Radiotherapy Ft. Collin Hayward, former CMO of Telix Pharma

63

3 Ways to Protect Your Reputation as a Hiring Manager

64

The Big Picture - Discussing Clinical Entry to Commercial Planning in Radiotherapy With Ben Pais, SVP Aricieum

65

Creating Shit Hot Authentic Stories to Sell Your Achievements

66

Discussing radiotherapy, AAA and CEO leadership with Riccardo Canevari: CEO of Radiopharm Theranostics

67

Radiotherapy 2024: Quick Look into the Radiotherapy Landscape

68

Ilaria Conti VP ADC Therapeutics - Female Leadership, Challenges in ADCs and Working in the US

69

Masterful Salary Negotiations: Less Fear, More Preparations and Get More of What You Want

70

Mats Hansen, CEO Spago Nanomedical: How to Lead a Radiotherapy Biotech

71

Podcast Trailer