A Dose of Reality with Charles Spence cover art

All Episodes

A Dose of Reality with Charles Spence — 72 episodes

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Title
1

Juho Jalkanen, CEO at Faron Pharmaceuticals on From Surgeon to CEO, Rethinking Boards, and Fighting for the Right Science

2

Tobias Kampfenkel, MD, MHBA, Vice President of Early Clinical Development and Translational Research at Miltenyi Biomedicine, on Transformative Drugs in Oncology and Autoimmunity: It's Always the Team!

3

Sofia Heigis, CEO of OncoPeptides, From Sales Rep to CEO, Being "Present", and Hiring for Self-Insight

4

Jens Lindberg, CEO at Medivir, on The Biotech Rollercoaster - Medivir´s Previous Four Months (and Biotech Today in 2026)

5

Hubert Truebel, Managing Director at DEBRA Research, on Creating Own Career Opportunities...and a Practical Approach to Longevity

6

Sampreet Ramachandra, Head of Hematology Business Unit at Novartis Germany, on Launching Without a Playbook, Hiring Mistakes, and Leading with Equity

7

Volker Wacheck, SVP at Taiho Oncology in Speaking Up, Asking vs. Accusing and Why Culture is So Important

8

Dena Grayson, MD, PhD, SVP Clinical Development & Medical Affairs at Kyverna Therapeutics on Media Training, Communication within Biotech, and Dealing with Fake CVs

9

Richard Nkulikiyinka, Chief Medical Officer at Antag Therapeutics, on Career Pivots, Trust and Why Leadership Is Never Linear

10

Prof. Dr. med. Markus Kosch, Head of Oncology Europe & Canada at Daiichi Sankyo on Perseverance, Patient-Centricity Beyond Slogans, and Leadership within Oncology

11

Myriam Cherif, Founder of Kalyx Medical, on The Future of MSLs, Adapting to AI, and Why Curiosity Keeps You Moving Forward

12

Sven Van den Berghe, CEO of Pantera on Overpromises in Isotope Marketing, Why Culture is the Company, and Discussions in RLT Development

13

Catello Somma, Partner at Seroba on Working in VC, Non-Linear Biotech Careers, and advice for those seeking VC careers

14

Kevin N. Heller, MD, Chief Medical Officer and Advisor to Funds and VCs, on Culture Shifts, Tough Lessons In Leadership, And The Reality Of Biotech Fundraising

15

Carl Deutsch, CSO at NBE Therapeutics in Non-Linear Careers, Age Bias, and Building Great Teams

16

Aleksandra Filipovic, Chief Medical Officer at Gallop Oncology on Perfectionism, Intuition, and the Risk of Building Unsafe Teams

17

Heidi Wang, CEO at OBI Pharma & Chairwoman at OBIGEN Pharma on Losing Her Father to Cancer, Hiring Without Humility, and Building a Culture That Lasts

18

András Strassz, MD, MBA, CMO at Heidelberg Pharma – Career Crossroads, Recruiting, and Culture Fit Over CVs

19

Steven Katz, MD, CMO and SVP of Translational Science for Shinobi Therapeutics & Professor of Surgery at Brown University - Hiring Without Regret, Team Mismatches, and the Cost of Playing It Safe in Biotech

20

Christian Mueller, CDO at Immutep on Career Crossroads, Culture Missteps, and the Recruitment Disconnect in Biotech

21

Kirsty Crame-van Nierop, Director of Shiaba Consulting, Specialist on Clinical Drug Development, in Broken Hiring Cycles, IND Wins, and Surviving Biotech Burnout

22

Bernhardt Zeiher, M.D. Member of the board of directors for Entrada Therapeutics, Amylyx Pharmaceuticals, and Abeona Therapeutics on Lessons from Leading a Global Development Organization

23

Ilya Gipp, CMO at GE Healthcare – Imaging’s Role in Oncology, Hiring Lessons, and How Culture Really Works

24

Michael Lahn, CMO at iOnctura – Osimertinib Success, TGF-Beta Lessons, Building Curious Teams, and More

25

Johan Baeck, EVP and CMO at Promontory Therapeutics – Cultural Fit in Hiring, Immunogenic Small Molecules, and Building Resilience in Biotech

26

Peter Tummino, President of R&D at Nimbus Therapeutics – Drugging the Undruggable, The TYK2 Success Story, and Overhyping AI in Drug Discovery

27

Abigail Jenkins, CEO and Board Member – From Government Scientist to CEO, Launching a Stem Cell Therapy During Crisis, and Lessons in Commercial Strategy

28

Joseph Birkett, Executive Director at Aura Biosciences – Obinutuzumab's Approval, CDK9 Trial Regret, CRO Reliance, and Building Respectful Cultures

29

Bruce Dezube, Senior Vice President, Clinical Development at Xilio Therapeutics – HIV & Cancer Drug Development, Career at 60, Building Respectful Teams, and More

30

Chris Lowe, CEO at Nusano - Radioisotopes, Volunteering in Hospitals, Culture Building, and More

31

Kevin Lynch, co-Founder PopulusBio - Career at Celgene, How Culture Influences Drug Development and more

32

Victor Paulus, SVP Regulatory Affairs at ARTBIO - Lutathera Approval and Lessons, Falling from Trees, ARTBIO's Culture

33

Chris Leamon, CSO at Fusion Therapeutics - Acquisition of Endocyte, Career reflections and more

34

Dawn Rubel, President R&D at NexEos Bio - Eosinophilic Esophagitis, Purposeful Leadership and more

35

Örn Almarsson, Co-Founder of Axelyf - Modernas SpikeVax, the challenge of mRNA delivery and Salmon's inspiration behind Axelyf?

36

Leila Jaafar, CEO at Nuclidium - from PhD to Radiotherapy CEO

37

CMO at Indaptus, Roger Waltzman, on Dangers of Pushing Uncertain Data into Phase III

38

Gertjan Bartlema, Co-founder Populus Bio and CEO of Immodulon Therapeutics. on Innovation in Biotechs

39

The 3 Most Common Rejection Reasons During an Interview

40

The Most Common Hiring Mistakes by Hiring Managers in 2024 ft. Caroline Vermeulen, Eminence

41

How and When to Ask Intelligent Interview Questions

42

Troels Jordansen, Executive Chairman of Keli Therapeutics, on Cell Therapy and Biotech Recession Talks

43

Negotiation Strategies and Insights from Harvard Course ft. Sophie He, Head of M&A and Partnering at Bracco

44

The 3 Interview Questions You Must Succeed In

45

Nikolaus Trede, SVP Clinical Development at Century Therapeutics - Lessons from Breyanzi and Global Cell Therapy Trials

46

Re-Entering the Workforce and Career Growth in Regulatory Affairs with Mary Christian

47

From Neuroscientist to Biotech Innovator ft.Anita Scheuber

48

Future-Proofing Your Organization Ft. Jackie Donovan

49

The Critical Role of Recruiters ft. Patrizio Renzetti

50

Bad Science vs. Good Leadership in Biotech ft. Sonal Kothari-Gupta, MD, PhD

51

Recruitment Strategies for High-Impact Hires with John Goldener

52

Hiring Strategies for Biotech Success ft. Sumeet Ambarkhane CMO at Alligator Bioscience

53

How to Outsource Your Job Search

54

Stealth biotech work, moving China trials to the US and more ft. Li Yan, former CMO of Brii and current CEO of upcoming stealth biotech

55

Building powerful relationships ft. Val Nassiri, previous VP of Medical Affairs at ITM and AAA.

56

Using Empathy to Build Internal Support

57

Sabine Brookman May VP Janssen - Listening in leadership, making beer and a career in drug development

58

The Biggest Selling Myth: Selling Through Talking

59

Effective Layoffs and treating people as humans ft. Crystal Zuckerman

60

Improve Your Selling Ability to Help Your Career

61

BIOSECURE Act - The potential $3.6bn+ gap, Impact on Jobs and Skills shifts with Amber Tong, Senior Editor at EndPoint News

62

My 10 Commandments to Recruitment

63

Discussions on Leadership, Hard decisions and Radiotherapy Ft. Collin Hayward, former CMO of Telix Pharma

64

3 Ways to Protect Your Reputation as a Hiring Manager

65

The Big Picture - Discussing Clinical Entry to Commercial Planning in Radiotherapy With Ben Pais, SVP Aricieum

66

Creating Shit Hot Authentic Stories to Sell Your Achievements

67

Discussing radiotherapy, AAA and CEO leadership with Riccardo Canevari: CEO of Radiopharm Theranostics

68

Radiotherapy 2024: Quick Look into the Radiotherapy Landscape

69

Ilaria Conti VP ADC Therapeutics - Female Leadership, Challenges in ADCs and Working in the US

70

Masterful Salary Negotiations: Less Fear, More Preparations and Get More of What You Want

71

Mats Hansen, CEO Spago Nanomedical: How to Lead a Radiotherapy Biotech

72

Podcast Trailer