All Episodes
Depresh Mode with John Moe — 312 episodes · page 1 of 4
E (from Eels) Talks Art, Persistence in the Face of Tragedy, and Cookie Monster
EShowbiz! For Murray Hill, it’s an Industry, Memoir, and Mantra
EAndy Frasco Is Figuring Out Who He IS When He’s NOT a Good Time Rock & Roll Frontman
EGabrielle Moss On Midlife Plot Twists and Just Not Talking To Your Mom Anymore
EMental Illness Before and After Pregnancy with Dr. Kara Zivin, Who Has Been There
ESinger Nicole Atkins Doesn’t Recommend Insomnia, Alcoholism, Falling Down Sinkholes
EAI Chatbots Destroyed His Reality. Dr. Jeremy Heffner Explains Why He Believed Them.
EBest of Depresh Mode: Cameron Esposito on Comedy, Rehab, and Bipolar Disorder
ECat Grief is Real. So is Human Grief. We’re Underestimating and Misunderstanding Both.
EOh, It’s Autism, Mary H.K. Choi Learned at 43. Okay, She Thought, That Explains a Lot.
EMargaret Glaspy Ends Her Instagram Addiction and Sings From Her Original Thought
EDepression, Loneliness, and Memory Problems Are Worse In Middle Age, But Only in America
ECodependency and Covid on a Tiny Boat in the Middle of the Ocean, with Angela Harger-Thompson
EMaybe It IS Time to Panic Over AI Chatbots and Mental Health with Maggie Harrison Dupré
EJo Dee Messina on Hard Times, Jesus, and Her First Album in 12 Years
EBest of Depresh Mode: Hanif Abdurraqib on Cultivating a Support System, Depression, Anxiety, and Basketball
EWe Should Praise Addiction, Not Condemn It, Says Anthropologist Elizabeth Roberts
ECartoonist Gemma Correll Saw a Therapist with a Clown-Festooned Office. Once.
ERFK Jr. Wants To Take Your SSRIs Away. So What Are Democrats Doing About It?
ERobyn Hitchcock is Fundamentally Delusional, Welcomes Birds
EBlake Mycoskie Helped the World, Got Rich, Retired to a Life of Ease, Then Fell Apart
EAn Episode About the Grind, Singer Zayna Youssef of Sweet Pill, and YOU
ETerrifying Times for Immigrants in America and Cristina Jimínez is Incredibly Hopeful
EClaude Steele on Churn, the Awkward Social Distress That Divides Us All
EConnecting Childhood Events To Your Stress Issues Today with Benjamin Wagner
ESampler Episode Depresh Meals
EBonus mini-sode: Checking In with Bill Corbett
EBonus Mini-Sode: A Dramatic Reading by Helen Hong and Interview with Playwright Sunny Kase
ECasters on Casters: John Moe and Brenda Snell
EAndy Richter on Divorce, Dating, Depression, and Dancing with the Stars
EBonus mini-sode: Checking In with Felicia Day
EBONUS CONTENT PREVIEW: All-Star Sad Songs That Make You Feel Better with Neko Case, Gavin Rossdale, and more
EJimmy Pardo on Being Funny, Depression, Anxiety, Trauma, Alcoholism, Contentment, and Being Funny Some More
EJoshua Roman on Long Covid, Cello, Charging Hard, and Brick Walls
EFeaturing Proxy with Yowei Shaw: Is it time to break up the band?
EAnnabelle Gurwitch: Author, Actor, Unexpectedly Still Alive
ETaking Small Steps That Form Great Strides with Eric Zimmer
EBonus Episode from In This Family: Ka Vang on War in Southeast Asia, ICE in Minnesota, and Mental Health Echoes
EBubbles of Love: Your Burnout Treatment, with Emily Nagoski
EGroup Therapy Royalty and First-Time Movie Star Elliot Zeisel From GROUP
EJonathan Edward Durham Was In Horrible Mental Shape But Didn’t Realize It
EHuge Scientific Breakthroughs Are Changing How You’ll Think About Eating Disorders
EAre Dating Apps a Mental Health Grenade? And, How Are Kids Doing in ICE-Era Minnesota?
ENiko Stratis on Dad Rock, Glasswork, Depression, Addiction, and Becoming Herself
ESPECIAL EPISODE: Mental Health and ICE in Minnesota
EAmanda Knox on Facing Her Prosecutor, Her Past, Her Trauma, and Her Future
EIntentionally Blunt and Very Useful Talk About Suicide with Clancy Martin
EStephanie Foo on Complex PTSD, Finding Recovery, and This American Life
EA.J. Daulerio on Bipolar, Substances, Depression, Suicide, and the Psychic Weight of Hulk Hogan
ETwo Truths To Make 2026 a Better Mental Health Year
EMike Doughty Was Recently Hospitalized for Depression Twice. It Helped.
ETom Johnson Advised LBJ, Ran CNN, and Drove Himself to Severe Depression
EAnger: Let’s Talk About It, Learn About It, Not Fear It, Use It For Good
EUnemployment Hurts Mental Health, Horror Movies Might Help It. Really!
EMaureen Johnson Became Friends with Her Anxiety Monster
EA Holiday Family Survival Mini-sode
EEsmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife
EIs Your Mental Health Diagnosis an Identity or Something More Meaningless?
EThe Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs
ESeasonal Affective Disorder and Why It Sucks So Bad
EIs Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So.
EIs the U.S. Government Going To Take Away Your Antidepressants?
EP.E. Moskowitz on Whether Your Mind is Broken or the World Is
EKendall Toole Gets Knocked Down, Never Knocked Out
EBruce Springsteen as Over-The-Counter Depression Treatment
EEmma Swift Had a Complete Mental Breakdown. Found Health. Made Music About It.
ESycophantic Chatbots and Alarming Cases of “AI Psychosis”
EAlex Edelman on ADHD, Grief, Infiltrating White Nationalists, and The Paper
EBetter Home Design for Better Mental Health with Dr. Beverly Walpole
EDenise Winkelman: Comedian/Trans Woman/Former Pro Wrestler/Chronic Pain Sufferer
EAshly Burch Delivers Mental Health Insight Using Puppets and Swear Words
EAuthor/Comedian Tiffany Jenkins on Anxiety, Addiction, Felonies, Success, and Not Wanting to Exist
EWe Have Two Guests This Week: Comedian Aaron Foster and His Depression
ENurse Blake on Gay Conversion Therapy, Panic Attacks, and, Well, Nursing
EGavin Rossdale of Bush on Loss, Xanax, and New Emotional Landscapes
EInsomnia and Mental Health Problems: Each Horrible, Each Feeding the Other
EPrison, Addiction, Bipolar, and Four Loko with Author Brandon Stickney
ESure, Maria Bamford Will Join Your Cult
EGinny & Georgia Creator Sarah Lampert on Getting Mental Health Right On Screen
EAlexandra Savior on bipolar disorder and being discovered by Courtney Love
EYou’re Not Imagining It, Climate Change IS Messing With Your Mental Health
ECan a Bipartisan Congressional Caucus Save Mental Health in America?
EEthan Sacks and Daughter Naomi Tackle Mental Health in Comics Form with A Haunted Girl
EFelicia Day on Depression, Anxiety, Achievement, Burnout, and Failed Prodigies
EThe Head And The Heart’s Kenny Hensley Injured Both Shoulders and That’s Where the Trouble Started
E988’s Future, Funding, and Online Fables
EGenerative AI Chatbot Delivers Great Results for Mental Health. Is “Therabot” the Future?
EPerfectly Hidden Depression: Do You Have It? With Dr. Margaret Rutherford
ECameron Esposito on Comedy, Rehab, and Bipolar Disorder
EThe Thorny Issue of Airline Pilots and Mental Illness
EHanif Abdurraqib on Cultivating a Support System, Depression, Anxiety, and Basketball
EChecking in With Friends: Open Mike Eagle
EWelcome, New Listeners
EJim James of My Morning Jacket on Depression, EMDR, Gratitude, and Taking Care of Jim
EBONUS CONTENT PREVIEW: Depresh Mode: The Game Show
EJohn Moe helps kick off MFD Spring Break
EJ. Kenji Lopez-Alt on Food, Booze, Weed, Anxiety, Depression, and Living a Healthy Life
EChecking in With Friends During Scary Times: Paul F. Tompkins, Ana Marie Cox, and Gary Gulman
EHeavy Substance Use, Heavy Depression, and Heavy Metal with Randy Blythe from Lamb of God
EMicrodosing with James Fadiman and Jordan Gruber
E