All Episodes
Depresh Mode with John Moe — 291 episodes
Best of Depresh Mode: Hanif Abdurraqib on Cultivating a Support System, Depression, Anxiety, and Basketball
We Should Praise Addiction, Not Condemn It, Says Anthropologist Elizabeth Roberts
Cartoonist Gemma Correll Saw a Therapist with a Clown-Festooned Office. Once.
RFK Jr. Wants To Take Your SSRIs Away. So What Are Democrats Doing About It?
Robyn Hitchcock is Fundamentally Delusional, Welcomes Birds
Blake Mycoskie Helped the World, Got Rich, Retired to a Life of Ease, Then Fell Apart
An Episode About the Grind, Singer Zayna Youssef of Sweet Pill, and YOU
Terrifying Times for Immigrants in America and Cristina Jimínez is Incredibly Hopeful
Claude Steele on Churn, the Awkward Social Distress That Divides Us All
Connecting Childhood Events To Your Stress Issues Today with Benjamin Wagner
Sampler Episode Depresh Meals
Bonus mini-sode: Checking In with Bill Corbett
Bonus Mini-Sode: A Dramatic Reading by Helen Hong and Interview with Playwright Sunny Kase
Casters on Casters: John Moe and Brenda Snell
Bonus mini-sode: Checking In with Felicia Day
BONUS CONTENT PREVIEW: All-Star Sad Songs That Make You Feel Better with Neko Case, Gavin Rossdale, and more
Jimmy Pardo on Being Funny, Depression, Anxiety, Trauma, Alcoholism, Contentment, and Being Funny Some More
Joshua Roman on Long Covid, Cello, Charging Hard, and Brick Walls
Featuring Proxy with Yowei Shaw: Is it time to break up the band?
Annabelle Gurwitch: Author, Actor, Unexpectedly Still Alive
Taking Small Steps That Form Great Strides with Eric Zimmer
Bonus Episode from In This Family: Ka Vang on War in Southeast Asia, ICE in Minnesota, and Mental Health Echoes
Bubbles of Love: Your Burnout Treatment, with Emily Nagoski
Group Therapy Royalty and First-Time Movie Star Elliot Zeisel From GROUP
Jonathan Edward Durham Was In Horrible Mental Shape But Didn’t Realize It
Huge Scientific Breakthroughs Are Changing How You’ll Think About Eating Disorders
Are Dating Apps a Mental Health Grenade? And, How Are Kids Doing in ICE-Era Minnesota?
Niko Stratis on Dad Rock, Glasswork, Depression, Addiction, and Becoming Herself
SPECIAL EPISODE: Mental Health and ICE in Minnesota
Amanda Knox on Facing Her Prosecutor, Her Past, Her Trauma, and Her Future
Intentionally Blunt and Very Useful Talk About Suicide with Clancy Martin
Stephanie Foo on Complex PTSD, Finding Recovery, and This American Life
A.J. Daulerio on Bipolar, Substances, Depression, Suicide, and the Psychic Weight of Hulk Hogan
Two Truths To Make 2026 a Better Mental Health Year
Tom Johnson Advised LBJ, Ran CNN, and Drove Himself to Severe Depression
Anger: Let’s Talk About It, Learn About It, Not Fear It, Use It For Good
Unemployment Hurts Mental Health, Horror Movies Might Help It. Really!
Maureen Johnson Became Friends with Her Anxiety Monster
A Holiday Family Survival Mini-sode
Esmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife
Is Your Mental Health Diagnosis an Identity or Something More Meaningless?
The Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs
Seasonal Affective Disorder and Why It Sucks So Bad
Is Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So.
Is the U.S. Government Going To Take Away Your Antidepressants?
P.E. Moskowitz on Whether Your Mind is Broken or the World Is
Kendall Toole Gets Knocked Down, Never Knocked Out
Bruce Springsteen as Over-The-Counter Depression Treatment
Emma Swift Had a Complete Mental Breakdown. Found Health. Made Music About It.
Sycophantic Chatbots and Alarming Cases of “AI Psychosis”
Alex Edelman on ADHD, Grief, Infiltrating White Nationalists, and The Paper
Better Home Design for Better Mental Health with Dr. Beverly Walpole
Denise Winkelman: Comedian/Trans Woman/Former Pro Wrestler/Chronic Pain Sufferer
Ashly Burch Delivers Mental Health Insight Using Puppets and Swear Words
Author/Comedian Tiffany Jenkins on Anxiety, Addiction, Felonies, Success, and Not Wanting to Exist
We Have Two Guests This Week: Comedian Aaron Foster and His Depression
Nurse Blake on Gay Conversion Therapy, Panic Attacks, and, Well, Nursing
Gavin Rossdale of Bush on Loss, Xanax, and New Emotional Landscapes
Insomnia and Mental Health Problems: Each Horrible, Each Feeding the Other
Prison, Addiction, Bipolar, and Four Loko with Author Brandon Stickney
Sure, Maria Bamford Will Join Your Cult
Ginny & Georgia Creator Sarah Lampert on Getting Mental Health Right On Screen
Alexandra Savior on bipolar disorder and being discovered by Courtney Love
You’re Not Imagining It, Climate Change IS Messing With Your Mental Health
Can a Bipartisan Congressional Caucus Save Mental Health in America?
Ethan Sacks and Daughter Naomi Tackle Mental Health in Comics Form with A Haunted Girl
The Head And The Heart’s Kenny Hensley Injured Both Shoulders and That’s Where the Trouble Started
988’s Future, Funding, and Online Fables
Generative AI Chatbot Delivers Great Results for Mental Health. Is “Therabot” the Future?
Perfectly Hidden Depression: Do You Have It? With Dr. Margaret Rutherford
Cameron Esposito on Comedy, Rehab, and Bipolar Disorder
The Thorny Issue of Airline Pilots and Mental Illness
Hanif Abdurraqib on Cultivating a Support System, Depression, Anxiety, and Basketball
Checking in With Friends: Open Mike Eagle
Welcome, New Listeners
Jim James of My Morning Jacket on Depression, EMDR, Gratitude, and Taking Care of Jim
BONUS CONTENT PREVIEW: Depresh Mode: The Game Show
John Moe helps kick off MFD Spring Break
J. Kenji Lopez-Alt on Food, Booze, Weed, Anxiety, Depression, and Living a Healthy Life
Checking in With Friends During Scary Times: Paul F. Tompkins, Ana Marie Cox, and Gary Gulman
Heavy Substance Use, Heavy Depression, and Heavy Metal with Randy Blythe from Lamb of God
Microdosing with James Fadiman and Jordan Gruber
Surviving Trauma and Having a Few Laughs with Ophira Eisenberg
Your Vagus Nerve: Key to Depression Relief? / Actor-Writer Kit Williamson
Neko Case on Pain, Neglect, Music, and Confidence
Dr. Emily Nagoski on Sex, Long Term Relationships, and Depression
Hari Kondabolu’s Life Was Transformed in Seattle
When Treating One Problem Creates A Whole Other Problem, with Alex Goldman
Truly Depressing Movies with Dana Stevens, Dan McCoy, and Drea Clark
Cory Richards on Climbing Mountains, Wrestling with Mental Health, Owning Up to His Past
Lead in Gasoline Has Damaged Your Mental Health and IQ, with Dr. Aaron Reuben
Richard Sarvate’s Mom Had Problematic Schizophrenia but Made Some Mean Chapatis
Comedian Ellie Hino and Her Later-In-Life ADHD Diagnosis
David Shaw of The Revivalists Finds His Heart Mode
LISTENER’S CHOICE: Adventures in the Army with the Bipolar General
Comedian Youngmi Mayer on Cultural Dissonance, Depression, Anxiety, Trauma, and Barry Gibb
13 Reasons For Hope in Mental Health
Mysterious Cancellations Block Veterans’ Mental Health Care
The Promising World of Precision Treatment for Depression
Bishop Briggs on Loss, Despair, and Finding Hope
Dr. Jessi Gold and the Precarious Mental Health of the Medical Profession
Xiu Xiu’s Jamie Stewart on Charting a Healing Path from Trauma
Zac Carper of FIDLAR on Bipolar, Drugs, Meds, and Intense Journaling
For Mental Health, Covid F***ed Our S*** Up and We’re Just Starting To Figure Out How
Election Stress Disorder and What To Do About it with Theresa Nguyen
Moon Unit Zappa on Family Trauma, Neglect, and Building a Self
The Muddy Ethical Ground of AI Mental Healthcare with Dr. Jodi Halpern
Rainbow Kitten Surprise’s Ela Melo on Music, the Stars, Psychosis, and Reality
Gut Health, Resilience, and What the Heck Is TMS Anyway?
Mike Doughty Was Recently Hospitalized for Depression Twice. It Helped.
Reframing Your Memories, Even the Terrible Ones, To Help Your Mental Health
Life Inside a Psych Unit and Therapy for Rock Bands
Gracie Gold, Olympic Figure Skater and Human with Mental Illness
The Decemberists’ Colin Meloy Opens Up About Lifelong Anxiety, Impostor Syndrome
A Regular Guy, Managing Trauma, Who Happens to Be Paul Scheer
Comedian Liz Miele on Depression, Trauma, Violence, and Live On-Stage Panic Attacks
Comedian Sierra Katow on Big Time Achievement and Persistent Depression
Chris Gethard is Less Ego-Driven, More Peaceful, No Longer Losing Teeth
The New York Times’ Ernesto Londoño Dives Deep Into the Psychedelic Treatment Experience
Our Guests Are Musician Judah Akers and, In a Sense, Elizabeth Kübler-Ross
Shannon & the Clams’ Shannon Shaw on Building Something Beautiful in the Wake of Tragedy
Shanti Das Turns From Helping Musicians to Helping Minds
Gary Gulman on Childhood, Depresh, and Leaving Food Comedy Behind
Advice on Mental Health in the Workplace with Megan Delp
Lindy West on Dealing with Online Jerks and Navigating Depression and ADHD
Todd Glass on Controlling One’s Environment
Leah Rudick: Stand Up Comedian, TikTok Superstar, Anxiety Haver
BONUS CONTENT PREVIEW: The Tables Have Turned and YOU Are the Interviewer
Jenny Lawson on Ketamine, Books, and Wendy’s Potatoes
WHY I'm Glad You're Here
Go Fact Yourself #MaxFunDrive Kick-off Spectacular featuring Jackie Kashian, Jeremy Bent, John Moe, and Dan McCoy
Joel Kim Booster Returns and Climbs Out of a Pit
Gracie Gold, Olympic Figure Skater and Human with Mental Illness
Kari Faux Stands Up to Her Original Bully
The Huge Importance of Human Support with Paul Gilmartin
Do You Need Some Financial Therapy?
Adventures in the Army with the Bipolar General
A Mental Health Crisis on College Campuses
Empathy, Compassion, and Trying To Read the News with Megan Devine
Devendra Banhart Is Sick of the Persistent Negative Internal Voice
So You Want To Be a Therapist? Interesting. Let’s Talk About That.
Susan Cain on Reaching a Quiet Life
Samantha Irby is Very Nervous About the Driver Behind Her
Noah Kahan’s Mental Health Is In His Songs
Seasonal Affective Disorder and Why It Sucks So Bad
The Best, Most Depressing Songs
Josh Ritter On Music, Depression, Religious Crises, and Bipolar II
Roxane Gay on Depression and the Trauma We Are All Sharing
Kevin Drew on Making Beautiful Music Out of Grief and Aging
Making Friends, Losing Friends, Anxiety, and Laughs
You’re Doing Self-Care All Wrong
Podcaster Jane Marie hires professional help for a life turned difficult
What is Anxiety Really Like? Author Jason Pargin Will Tell You.
Managing Your Mind When the Music Fades
Parker Molloy on Depression, Anxiety, and Being Trans in America Today
Felicia Day on Depression, Anxiety, Achievement, Burnout, and Failed Prodigies
Comedian Aparna Nancherla is Neither Perfect Nor an Impostor
Investigating Your Family, Uncovering Shame and Secrecy
Lydia Loveless Keeps Laughing and Writing About Suicidal Ideation
Sure, Maria Bamford Will Join Your Cult
Actor Patrick Page Knows How to Get to the Dark Places
The Misnomer That is Impostor Syndrome
Jamie Lee Curtis: Self-Professed Dope Fiend of Show-off Business (Aired August 1, 2022)
Sasheer Zamata on SNL, Buzz Lightyear, and Panic Attacks
Bethany Cosentino On Inner Child Work, ADHD, and Making Sense of the World
Nick Seluk of Those Delightful Heart and Brain Comics
Dr. Laurie Santos on How to Get More Happiness (Aired September 12, 2022)
Emi Nietfeld on Mental Health, Trauma, and Acceptance
Dogs Who Are Always There For You and Friends Who May Not Be
Noah Kahan’s Mental Health Is In His Songs
Michael Landsberg Gives Up the Highs to Escape the Lows
The Dark Nebraska of Bruce Springsteen
Sen. Tina Smith on Mental Health
The Legacy of a Narcissist
Cheryl Strayed on Wise Inner Sage Voices
Samantha Irby is Very Nervous About the Driver Behind Her
It’s Mental Health Awareness Month and We Are Winning
Mental Health Support While You Game
Lori Gottlieb on How to Get the Most Out of Therapy
Ana Marie Cox on Writing Your Recovery Story
Chris Powell: Reality TV Star, Fitness Guru, Person With Mental Illness
Bonus Content Preview: What Works For Me
Gary Gulman Is Feeling Much Better
Dana Gould Was His Own Parent and He Sucked At It Real Bad
Episodes We Just Can’t Stop Thinking About
Rachel Smythe, Creator of Lore Olympus, on Gods and Humanity
Zach Zimmerman Thought He Was Going to Hell, Which Was Depressing
BONUS EPISODE: Sleeping with Celebrities - Andy Daly Tends His Own Lawn
Neal Brennan Has Tried a LOT of Things
Household Chores, Struggle Care, and Your Mental Health
Christian Finnegan Carries Baggage, Makes Jokes
Chris Walla on Quitting, Norway, Alcohol, Perfectionism, and Terrible Music Teachers
Autism In Your Mental Health Mix
Kate Beaton on Isolation, Oil, and Ducks
Paulina Porizkova Without Filters
Stories That David Sedaris is Finally Free to Tell (Aired June 13, 2022)
Kim-Joy of The Great British Bake-Off
Holiday Survival for People With Complicated Minds
Comics Creator Ellen Forney on Bipolar and a Monster Named Smedmerts
The Power of Story in Shaping Mental Health
The Whimsy and Depth of Depressed Cake Shop
Psychedelically Tripping Out For Your Mental Health
Kristin Hersh Wanted to Play Magenta Chords
Jason Kander on War, Politics, and PTSD
Tabitha Soren on Photography, Panic Attacks, and Overwhelming Grief
The Surgeon General Wants Your Boss To Build You a Healthier Workplace
Song Exploder’s Hrishikesh Hirway Becomes a Creative Block Exploder
The Hilarious World of Depression, a memoir
Kevin Love: All-Star in the NBA and in Destigmatization
Mental Health Expert Says YOU are a Mental Health Expert
Annie Weisman on Bulimia, Television, Catharsis, and Rude Internal Monologues
Dr. Laurie Santos on How to Get More Happiness
Jonathan Ames, Detectives, and Your Own Mysteries
Lola Kirke on Body Image, Music, Acting, and Being a Lady For Sale
Elizabeth Ito on Anxiety, Art, and Things You Can’t Control
Gaby Dunn on Bipolar Disorder, Gender, Sexuality, and Personal Finance
Tom Scharpling on Suicidal Ideation, Depression, In-Patient Care, ECT, and Memory Loss
Jamie Lee Curtis: Self-Professed Dope Fiend of Show-off Business
Shane Koyczan Says Sometimes “Bullying” Is Just Assault
Jamie Loftus Wasn’t a Budding Journalist, She Had Friggin’ OCD
Justin McElroy: My Anxiety, My Anxiety, and Me
Faith Salie Was Miss Aphrodite, Then Things Got Complicated
Is Tim Heidecker Depressed or Does He Just Sing About It Very Accurately?
Stories That David Sedaris is Finally Free to Tell
Ginny Hogan Has More Mental Health Issues Than a Plate of Refried Beans Does
Jamie Tworkowski of To Write Love On Her Arms
Maggie Smith on Despair, Hope, Divorce, and Poetry
The Language of Mental Health
Shamir Hits It Big in Music, Looks for Retail Jobs
S.E. Cupp, Panic Attacks, Breakdowns, and Making New Boundaries
John Darnielle of The Mountain Goats on Anxiety, Violence, Drugs, Youth in Peril, and TikTok
Sarah and Nippy Sought Self-Improvement, Ended Up in a Cult
Now We’re Two Years Into Covid and Burnout Has Gotten So Much Worse
You’re Wrong About ADHD with Sarah Marshall from You’re Wrong About
Dylan Marron Has Conversations With People Who Hate Him
Liz Scheier’s Mom Had Borderline Personality Disorder and Some Heavy Secrets
Nick Kroll and Brandon Kyle Goodman Have Emotional Meetings with Human Resources
Joel Kim Booster Is In A Pit
Patty Schemel Was Introduced to Bacardi and The Clash in the Same Moment
When Home DNA Tests Blow Up Everything You Thought You Knew
Shelley Had Dissociative Identity Disorder. You Have Multiple Personalities.
Drew Magary on a Mysterious Traumatic Brain Injury, a Coma, an Intolerable Personality, and a Recovery
Jen Kirkman on Anxiety, Epiphanies, and How to be an Unacceptable Airline Passenger
The Sex Episode
Amanda Knox on the Difference Between Exoneration and Freedom
Connor Franta’s Struggles With Identity, Sexuality, and Mental Health Are Available on YouTube
The View From Inside ADHD with Carolina Hidalgo and Dave Holmes
It’s Not You, It’s The World: Covid, Mental Health, and What Comes Next
Our Wildly Speculative and Totally Unqualified Psychological Analysis of Major Christmas Characters
Bridger Winegar Had a Nervous Breakdown on a Mormon Mission, Which is Never Good
Aimee Mann Couldn’t Hear Very Well or Write Songs. That’s Inconvenient Because She’s Aimee Mann.
Broti Gupta Would Prefer Not To Be Serious For Even One Hour, Thank You
Josh Gondelman, the Good Boy of Comedy, is Somehow Just Fine. Gary Gulman is Baffled.
Ivan Maisel Wants To Tell You About His Son Max
Let’s Get Our Minds Ready For the Gig Economy
The Beautiful World of Mentally Nutritious Video Games
Lane Moore on Being Alone, and Not Swiping Right on Naked Blood-Soaked Guys
Meet the Neighbors: Depresh Mode with John Moe x Go Fact Yourself
Amos Lee Gets Deep, Gets Dark, Makes Jokes
Tom Scharpling on Suicidal Ideation, Depression, In-Patient Care, ECT, and Memory Loss
Six Things You Need To Know For Your Mental Health
Alison Rosen on Postpartum Depression, the Anxiety of Scales, and Best Friendship
Janet Varney Wasn’t In Being John Malkovich. But She Lived It.
Movies and TV Shows That Get Mental Illness Right and Some That Get It Wrong
Jackie Kashian Did What You Should Do
School is Starting, Kids are Psychologically Messed Up, and We All Need to Help
Meditation is Good and Helpful and Doesn’t Require All That Woo-Woo Mysticism
Tuca & Bertie’s Lisa Hanawalt on Depression, Anxiety, Panic Attacks, and Funneling All That Knowledge Into Cartoon Birds
How to Express Concern About Someone’s Mental Health and When to Shut Up About It
Griffin Newman with Co-Stars Depression, Anxiety, Comedy, Lousy Bikes, The Tick, Kevin Costner, and Woody Allen
Song Imploder with A.C. Newman of The New Pornographers feat. Anxiety and Depression
Depression, Anxiety, and Devil Horns: Chelsea Ursin Saves Her Soul with Rock n’ Roll
Kelly Williams Brown Has Bad Times With Mental Health, Physical Health, and Marriage But Better Times With Crafts
“Hey, Topics! You’re Not So Tough! Wait! Ow! Yes You Are!” with Anna Sale
Joel Kim Booster Is In A Pit
Eating Disorders, What We Knew Before and What We Know Now, with Alexandra Paul
Grief Feels Like You’re Losing Your Mind. But ARE You?
Stephanie Wittels Wachs and the Pain and Frustration of Watching Addiction Happen
Bipolar 101: What It Is and What It Isn’t with Ana Marie Cox & Dr. Ken Duckworth
Pretty Sure Allison Raskin Knows More About OCD Than Khloé Kardashian
Jarrett Hill and the Quest for the Therapist Who Knows What You’re Talking About
Mental Health Care is On Screens For Good Now, Let’s Get Ready
Zach Kornfeld of The Try Guys, Ira Glass, and Rhett Miller Separately But Related By a Theme
Peter Sagal Has These New People In His House
What To Expect When The Virus Is Gone But COVID Trauma Goes On
Jenny Lawson, Magnets, Puppetry, and Small Business Ownership
Open Mike Eagle, the Former Obfuscating Mike Eagle
If You're Miserable At Work, Maybe It's Not Your Fault
Patton Oswalt Talks About It Because It Happened
Kelsey Darragh Lives Out Loud
Coming March 29th!